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Prospective phase I trial of conservative management of low rectal lesions.

Publication ,  Journal Article
McCready, DR; Ota, DM; Rich, TA; Thielvoldt, D; Jessup, JM
Published in: Arch Surg
January 1989

The purpose of this study was to assess and function and to compare the morbidity of local excision and postoperative radiotherapy for rectal adenocarcinoma with the morbidity of abdominoperineal resection. A posterior parasacral approach was used for local excision. All patients had negative margins, and all but one were continent after completion of radiotherapy. Seven patients (29%) had either a wound infection or a fistula in the local excision group. No local failures occurred, although follow-up was only 13 months. Thirteen (50%) of the 26 patients who underwent an abdominoperineal resection developed at least one complication. Combined treatment that spares the rectal sphincters may be preferable in selected patients with low rectal cancer, if long-term disease-free survival is maintained.

Duke Scholars

Published In

Arch Surg

DOI

ISSN

0004-0010

Publication Date

January 1989

Volume

124

Issue

1

Start / End Page

67 / 70

Location

United States

Related Subject Headings

  • Surgery
  • Rectal Neoplasms
  • Prospective Studies
  • Postoperative Complications
  • Muscle Contraction
  • Middle Aged
  • Methods
  • Male
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McCready, D. R., Ota, D. M., Rich, T. A., Thielvoldt, D., & Jessup, J. M. (1989). Prospective phase I trial of conservative management of low rectal lesions. Arch Surg, 124(1), 67–70. https://doi.org/10.1001/archsurg.1989.01410010077016
McCready, D. R., D. M. Ota, T. A. Rich, D. Thielvoldt, and J. M. Jessup. “Prospective phase I trial of conservative management of low rectal lesions.Arch Surg 124, no. 1 (January 1989): 67–70. https://doi.org/10.1001/archsurg.1989.01410010077016.
McCready DR, Ota DM, Rich TA, Thielvoldt D, Jessup JM. Prospective phase I trial of conservative management of low rectal lesions. Arch Surg. 1989 Jan;124(1):67–70.
McCready, D. R., et al. “Prospective phase I trial of conservative management of low rectal lesions.Arch Surg, vol. 124, no. 1, Jan. 1989, pp. 67–70. Pubmed, doi:10.1001/archsurg.1989.01410010077016.
McCready DR, Ota DM, Rich TA, Thielvoldt D, Jessup JM. Prospective phase I trial of conservative management of low rectal lesions. Arch Surg. 1989 Jan;124(1):67–70.

Published In

Arch Surg

DOI

ISSN

0004-0010

Publication Date

January 1989

Volume

124

Issue

1

Start / End Page

67 / 70

Location

United States

Related Subject Headings

  • Surgery
  • Rectal Neoplasms
  • Prospective Studies
  • Postoperative Complications
  • Muscle Contraction
  • Middle Aged
  • Methods
  • Male
  • Humans
  • Female