David Masao Ota | Scholars@Duke

David Masao Ota
Professor of Surgery

Current Appointments & Affiliations

Professor of Surgery, Surgical Oncology, Surgery 2006
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2005

Contact Information

7023 North Pavilion, 2400 Pratt Street, Durham, NC 27705
Box 3850 Med Ctr, Durham, NC 27710
david.ota@duke.edu (919) 668-5987

Background
Education, Training, & Certifications
- M.D., The University of Chicago 1973
Duke Appointment History
- Consulting Professor of Surgery, Surgery, Clinical Science Departments 2005 - 2006
Research
Selected Grants
- Support for Specimen Banking in ACOSOG GY 6 awarded by National Institutes of Health 2005 - 2012
- ACOSOG Competing Renewal awarded by National Institutes of Health 2008 - 2011
- ACOSOG Supplemental Z1072 awarded by National Institutes of Health 2008 - 2010
- ACOSOG Grant Year 11 awarded by National Institutes of Health 1998 - 2007
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Lesurf, R., O. L. Griffith, M. Griffith, J. Hundal, L. Trani, M. A. Watson, R. Aft, et al. “Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial.” Ann Oncol 28, no. 5 (May 1, 2017): 1070–77. https://doi.org/10.1093/annonc/mdx048.
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  - Ellis, Matthew J., Vera J. Suman, Jeremy Hoog, Rodrigo Goncalves, Souzan Sanati, Chad J. Creighton, Katherine DeSchryver, et al. “Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).” J Clin Oncol 35, no. 10 (April 1, 2017): 1061–69. https://doi.org/10.1200/JCO.2016.69.4406.
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  - McCarter, Martin D., Cristina R. Antonescu, Karla V. Ballman, Robert G. Maki, Peter W. T. Pisters, George D. Demetri, Charles D. Blanke, et al. “Microscopically positive margins for primary gastrointestinal stromal tumors: analysis of risk factors and tumor recurrence.” J Am Coll Surg 215, no. 1 (July 2012): 53–59. https://doi.org/10.1016/j.jamcollsurg.2012.05.008.
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  - McDonald, Sandra A., Elaine R. Mardis, David Ota, Mark A. Watson, John D. Pfeifer, and Jonathan M. Green. “Comprehensive genomic studies: emerging regulatory, strategic, and quality assurance challenges for biorepositories.” Am J Clin Pathol 138, no. 1 (July 2012): 31–41. https://doi.org/10.1309/AJCPXBA69LNSCVMH.
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  - Ellis, Matthew J., Li Ding, Dong Shen, Jingqin Luo, Vera J. Suman, John W. Wallis, Brian A. Van Tine, et al. “Whole-genome analysis informs breast cancer response to aromatase inhibition.” Nature 486, no. 7403 (June 10, 2012): 353–60. https://doi.org/10.1038/nature11143.
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  - Diehl, Kathleen M., Erin M. Green, Armin Weinberg, Wayne A. Frederick, Dennis R. Holmes, Bettye Green, Arden Morris, et al. “Features associated with successful recruitment of diverse patients onto cancer clinical trials: report from the American College of Surgeons Oncology Group.” Ann Surg Oncol 18, no. 13 (December 2011): 3544–50. https://doi.org/10.1245/s10434-011-1818-9.
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  - Ota, David M., A Marilyn Leitch, and Gary Unzeitig. “American College of Surgeons Oncology Group and the community surgeon.” Surg Oncol Clin N Am 20, no. 3 (July 2011): 439–vii. https://doi.org/10.1016/j.soc.2011.01.006.
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  - You, Y Nancy, Lisa Jacobs, Elizabeth Martinez, and David M. Ota. “The audit process and how to ensure a successful audit.” Cancer Treat Res 132 (2007): 179–97. https://doi.org/10.1007/978-0-387-33225-3_9.
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  - You, Y Nancy, Lisa Jacobs, Elizabeth D. Martinez, Susan C. Budinger, E Jean Wittlief, Shelley K. Myles, David M. Ota, and David M. American College of Surgeons Oncology Group. “Improved surgeon performance in clinical trials: an analysis of quality assurance audits from the American College of Surgeons Oncology Group.” J Am Coll Surg 203, no. 3 (September 2006): 269–76. https://doi.org/10.1016/j.jamcollsurg.2006.05.298.
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  - You, Y Nancy, Kelly K. Hunt, Mitchell C. Posner, Joe B. Putnam, Heidi Nelson, David M. Ota, and Peter W. T. Pisters. “Operative trials: the opportunity beckons-an update on the American College of Surgeons Oncology Group.” Surgery 139, no. 4 (April 2006): 455–59. https://doi.org/10.1016/j.surg.2005.08.008.
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  - Newman, Lisa A., Cheryl T. Lee, Lina Patel Parekh, Andrew K. Stewart, Charles R. Thomas, Robert A. Beltran, Anthony Lucci, et al. “Use of the National Cancer Data Base to develop clinical trials accrual targets that are appropriate for minority ethnicity patients: a report from the American College of Surgeons Oncology Group (ACOSOG) Special Population Committee.” Cancer 106, no. 1 (January 1, 2006): 188–95. https://doi.org/10.1002/cncr.21592.
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  - Redlich, Philip N., Anna C. Purdy, Vinod B. Shidham, Hyun J. Yun, Alonzo Walker, and David Ota. “Feasibility of breast duct lavage performed by a physician extender.” Surgery 136, no. 5 (November 2004): 1077–80. https://doi.org/10.1016/j.surg.2004.08.004.
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  - Lin, Kevin M., Tarak H. Patel, Adrian Ray, Matthew Ota, Lisa Jacobs, Boris Kuvshinoff, Mathew Chung, Michael Watson, and David M. Ota. “Intradermal radioisotope is superior to peritumoral blue dye or radioisotope in identifying breast cancer sentinel nodes.” J Am Coll Surg 199, no. 4 (October 2004): 561–66. https://doi.org/10.1016/j.jamcollsurg.2004.06.018.
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  - Clinical Outcomes of Surgical Therapy Study Group, David, Heidi Nelson, Daniel J. Sargent, H Sam Wieand, James Fleshman, Mehran Anvari, Steven J. Stryker, et al. “A comparison of laparoscopically assisted and open colectomy for colon cancer.” N Engl J Med 350, no. 20 (May 13, 2004): 2050–59. https://doi.org/10.1056/NEJMoa032651.
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  - Annie Yu, Hwei-Ju, Kevin M. Lin, David M. Ota, and Henry T. Lynch. “Hereditary nonpolyposis colorectal cancer: preventive management.” Cancer Treat Rev 29, no. 6 (December 2003): 461–70. https://doi.org/10.1016/s0305-7372(03)00084-7.
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  - Ota, David M. “What's new in general surgery: surgical oncology.” J Am Coll Surg 196, no. 6 (June 2003): 926–32. https://doi.org/10.1016/S1072-7515(03)00296-5.
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  - Heidemann, Jan, Hitoshi Ogawa, Michael B. Dwinell, Parvaneh Rafiee, Christian Maaser, Henning R. Gockel, Mary F. Otterson, et al. “Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2.” J Biol Chem 278, no. 10 (March 7, 2003): 8508–15. https://doi.org/10.1074/jbc.M208231200.
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  - Kuvshinoff, Boris W., and David M. Ota. “Radiofrequency ablation of liver tumors: influence of technique and tumor size.” Surgery 132, no. 4 (October 2002): 605–11. https://doi.org/10.1067/msy.2002.127545.
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  - Ota, David M., Lisa Jacobs, and Boris Kuvshinoff. “Rectal cancer: the sphincter-sparing approach.” Surg Clin North Am 82, no. 5 (October 2002): 983–93. https://doi.org/10.1016/s0039-6109(02)00048-8.
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  - Lin, Kevin M., Fausto Rodriguez, and David M. Ota. “The sentinel node in colorectal carcinoma. Mapping technique, pathologic assessment, and clinical relevance.” Oncology (Williston Park) 16, no. 5 (May 2002): 567–80.
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  - Nelson, H., N. Petrelli, A. Carlin, J. Couture, J. Fleshman, J. Guillem, B. Miedema, D. Ota, D. Sargent, and D. National Cancer Institute Expert Panel. “Guidelines 2000 for colon and rectal cancer surgery.” J Natl Cancer Inst 93, no. 8 (April 18, 2001): 583–96. https://doi.org/10.1093/jnci/93.8.583.
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  - Kuvshinoff, B., I. Maghfoor, B. Miedema, M. Bryer, S. Westgate, J. Wilkes, and D. Ota. “Distal margin requirements after preoperative chemoradiotherapy for distal rectal carcinomas: are < or = 1 cm distal margins sufficient?” Ann Surg Oncol 8, no. 2 (March 2001): 163–69. https://doi.org/10.1007/s10434-001-0163-9.
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  - Ota, D. M., and K. Lin. “Lymphatic mapping and sentinel node identification for colorectal cancer.” Swiss Surg 7, no. 6 (2001): 252–55. https://doi.org/10.1024/1023-9332.7.6.252.
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  - Lin, K. M., and D. M. Ota. “Laparoscopic colectomy for cancer: an oncologic feasible option.” Surg Oncol 9, no. 3 (November 2000): 127–34. https://doi.org/10.1016/s0960-7404(01)00002-0.
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  - Ota, D. M. “Treatment of primary colon cancer with peritoneal carcinomatosis: Comparison of concomitant vs. delayed management - Invited editorial.” Diseases of the Colon & Rectum 43, no. 10 (October 2000): 1347–1347. https://doi.org/10.1007/BF02236628.
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  - John, M. J., G. S. Merrick, L. R. Coia, B. D. Minsky, J. L. Bader, N. A. Janjan, D. Raben, et al. “Anal cancer. American College of Radiology. ACR Appropriateness Criteria.” Radiology 215 Suppl (June 2000): 1501–11.
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  - Rich, T. A., D. Ota, S. A. Rosenthal, B. D. Minsky, J. L. Bader, L. R. Coia, N. A. Janjan, et al. “Management of resectable rectal cancer. American College of Radiology. ACR Appropriateness Criteria.” Radiology 215 Suppl (June 2000): 1473–80.
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  - Saltz, L., D. Raben, B. D. Minsky, J. L. Bader, L. R. Coia, N. A. Janjan, M. J. John, et al. “Rectal cancer: presentation with metastatic and locally advanced disease. American College of Radiology. ACR Appropriateness Criteria.” Radiology 215 Suppl (June 2000): 1491–99.
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  - Tepper, J. E., J. L. Bader, N. A. Janjan, B. D. Minsky, L. R. Coia, M. J. John, G. S. Merrick, et al. “Locally unresectable rectal cancer. American College of Radiology. ACR Appropriateness Criteria.” Radiology 215 Suppl (June 2000): 1481–90.
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  - Ajani, J. A., P. F. Mansfield, P. M. Lynch, P. W. Pisters, B. Feig, P. Dumas, D. B. Evans, et al. “Enhanced staging and all chemotherapy preoperatively in patients with potentially resectable gastric carcinoma.” J Clin Oncol 17, no. 8 (August 1999): 2403–11. https://doi.org/10.1200/JCO.1999.17.8.2403.
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  - Bold, Richard J., David M. Ota, Jaffer A. Ajani, and Paul F. Mansfield. “Peritoneal and serum tumor markers predict recurrence and survival of patients with resectable gastric cancer.” Gastric Cancer 2, no. 1 (May 1999): 1–7. https://doi.org/10.1007/s101200050013.
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  - Bouvet, M., P. F. Mansfield, J. M. Skibber, S. A. Curley, L. M. Ellis, G. G. Giacco, A. R. Madary, D. M. Ota, and B. W. Feig. “Clinical, pathologic, and economic parameters of laparoscopic colon resection for cancer.” Am J Surg 176, no. 6 (December 1998): 554–58. https://doi.org/10.1016/s0002-9610(98)00261-x.
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  - Lieber, K. A., S. B. Standiford, B. W. Kuvshinoff, and D. M. Ota. “Surgical management of aberrant sentinel lymph node drainage in cutaneous melanoma.” Surgery 124, no. 4 (October 1998): 757–61. https://doi.org/10.1067/msy.1998.90943.
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  - Ota, D. M. “Colon cancer.” Cancer Treat Res 90 (1997): 347–56. https://doi.org/10.1007/978-1-4615-6165-1_18.
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  - Ota, D. M. “Laparoscopic resection for colon cancer: a favorable view.” Important Adv Oncol, 1996, 227–29.
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  - Ota, D. M. “Laparoscopic colon resection for cancer--a favorable view.” Adv Surg 29 (1996): 141–53.
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  - Skibber, J. M., D. A. Swanson, F. C. Ames, D. M. Ota, and R. E. Pollock. “Complications of intestinal anastomosis in patients with right colectomy and ileal conduit: The M. D. Anderson Experience.” Journal of Pelvic Surgery 2, no. 5 (January 1, 1996): 234–38.
  - Ota, D. M. “Laparoscopic colon resection for cancer.” Surg Endosc 9, no. 12 (December 1995): 1318–22.
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  - Rich, T. A., J. M. Skibber, J. A. Ajani, D. J. Buchholz, K. R. Cleary, R. A. Dubrow, B. Levin, P. M. Lynch, S. H. Meterissian, and L. D. Roubein. “Preoperative infusional chemoradiation therapy for stage T3 rectal cancer.” Int J Radiat Oncol Biol Phys 32, no. 4 (July 15, 1995): 1025–29. https://doi.org/10.1016/0360-3016(95)00020-y.
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  - Weinstein, G. D., T. A. Rich, C. R. Shumate, J. M. Skibber, K. R. Cleary, J. A. Ajani, and D. M. Ota. “Preoperative infusional chemoradiation and surgery with or without an electron beam intraoperative boost for advanced primary rectal cancer.” Int J Radiat Oncol Biol Phys 32, no. 1 (April 30, 1995): 197–204. https://doi.org/10.1016/0360-3016(94)00481-y.
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  - Ajani, J. A., P. F. Mansfield, and D. M. Ota. “Potentially resectable gastric carcinoma: current approaches to staging and preoperative therapy.” World J Surg 19, no. 2 (March 1995): 216–20. https://doi.org/10.1007/BF00308629.
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  - Ota, D., B. Loftin, T. Saito, R. Lea, and J. Keller. “Virtual reality in surgical education.” Comput Biol Med 25, no. 2 (March 1995): 127–37. https://doi.org/10.1016/0010-4825(94)00009-f.
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  - Kim, Y. H., J. A. Ajani, D. M. Ota, P. Lynch, and J. A. Roth. “Value of serial carcinoembryonic antigen levels in patients with resectable adenocarcinoma of the esophagus and stomach.” Cancer 75, no. 2 (January 15, 1995): 451–56. https://doi.org/10.1002/1097-0142(19950115)75:2<451::aid-cncr2820750207>3.0.co;2-u.
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  - Mansfield, P. F., D. C. Hohn, B. D. Fornage, M. A. Gregurich, and D. M. Ota. “Complications and failures of subclavian-vein catheterization.” N Engl J Med 331, no. 26 (December 29, 1994): 1735–38. https://doi.org/10.1056/NEJM199412293312602.
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  - Feig, B. W., D. H. Berger, T. B. Dougherty, J. F. Dupuis, B. Hsi, R. C. Hickey, and D. M. Ota. “Pharmacologic intervention can reestablish baseline hemodynamic parameters during laparoscopy.” Surgery 116, no. 4 (October 1994): 733–39.
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  - Elftmann, T. D., H. Nelson, D. M. Ota, J. H. Pemberton, and R. W. Beart. “Laparoscopic-assisted segmental colectomy: surgical techniques.” Mayo Clin Proc 69, no. 9 (September 1994): 825–33. https://doi.org/10.1016/s0025-6196(12)61783-2.
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  - Staley, C. A., M. Miller, T. J. King, M. Clem, and D. M. Ota. “Laparoscopic intracorporeal harvest of jejunal tissue for autologous transplantation.” Surg Laparosc Endosc 4, no. 3 (June 1994): 192–95.
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  - Fuhrman, G. M., and D. M. Ota. “Laparoscopic intestinal stomas.” Dis Colon Rectum 37, no. 5 (May 1994): 444–49. https://doi.org/10.1007/BF02076189.
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  - Meterissian, S., J. Skibber, T. Rich, L. Roubein, J. Ajani, K. Cleary, and D. M. Ota. “Patterns of residual disease after preoperative chemoradiation in ultrasound T3 rectal carcinoma.” Ann Surg Oncol 1, no. 2 (March 1994): 111–16. https://doi.org/10.1007/BF02303553.
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  - Mak, A. C., T. A. Rich, T. E. Schultheiss, B. Kavanagh, D. M. Ota, and M. M. Romsdahl. “Late complications of postoperative radiation therapy for cancer of the rectum and rectosigmoid.” Int J Radiat Oncol Biol Phys 28, no. 3 (February 1, 1994): 597–603. https://doi.org/10.1016/0360-3016(94)90184-8.
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  - Nakamori, S., D. M. Ota, K. R. Cleary, K. Shirotani, and T. Irimura. “MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma.” Gastroenterology 106, no. 2 (February 1994): 353–61. https://doi.org/10.1016/0016-5085(94)90592-4.
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  - Irimura, T., Y. Izumi, Y. Kawamura, S. Nakamori, I. J. Fidler, K. R. Cleary, and D. M. Ota. “Carbohydrate-mediated cell adhesion as a determinant of colorectal cancer metastasis.” Cancer Bulletin 46, no. 4 (January 1, 1994): 336–43.
  - Ota, D. M. “Laparoscopic Management of Colon Cancer.” Surgical Innovation 1, no. 1 (January 1, 1994): 18–25. https://doi.org/10.1177/155335069400100105.
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  - Ota, D. M., H. Nelson, and J. C. Weeks. “Controversies regarding laparoscopic colectomy for malignant diseases.” Curr Opin Gen Surg, 1994, 208–13.
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  - Ajani, J. A., R. J. Mayer, D. M. Ota, G. D. Steele, D. Evans, M. Roh, D. J. Sugarbaker, P. Dumas, C. Gray, and D. A. Vena. “Preoperative and postoperative combination chemotherapy for potentially resectable gastric carcinoma.” J Natl Cancer Inst 85, no. 22 (November 17, 1993): 1839–44. https://doi.org/10.1093/jnci/85.22.1839.
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  - Irimura, T., S. Nakamori, Y. Matsushita, Y. Taniuchi, N. Todoroki, T. Tsuji, Y. Izumi, Y. Kawamura, S. D. Hoff, and K. R. Cleary. “Colorectal cancer metastasis determined by carbohydrate-mediated cell adhesion: role of sialyl-LeX antigens.” Semin Cancer Biol 4, no. 5 (October 1993): 319–24.
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  - Grossie, V. B., J. Yick, M. Alpeter, T. C. Welbourne, and D. M. Ota. “Glutamine stability in biological tissues evaluated by fluorometric analysis.” Clin Chem 39, no. 6 (June 1993): 1059–63.
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  - Rich, T. A., J. A. Ajani, W. H. Morrison, D. Ota, and B. Levin. “Chemoradiation therapy for anal cancer: radiation plus continuous infusion of 5-fluorouracil with or without cisplatin.” Radiother Oncol 27, no. 3 (June 1993): 209–15. https://doi.org/10.1016/0167-8140(93)90076-k.
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  - Shumate, C. R., T. A. Rich, J. M. Skibber, J. A. Ajani, and D. M. Ota. “Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma. A report of surgical morbidity.” Cancer 71, no. 11 (June 1, 1993): 3690–96. https://doi.org/10.1002/1097-0142(19930601)71:11<3690::aid-cncr2820711136>3.0.co;2-h.
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  - Rich, T. A., N. H. A. Terry, M. Meistrich, K. Cleary, and D. Ota. “Pathologic, anatomic, and biologic factors correlated with local recurrence of colorectal cancer.” Seminars in Radiation Oncology 3, no. 1 (January 1, 1993): 13–19. https://doi.org/10.1016/S1053-4296(05)80073-6.
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  - Grossie, V. B., K. Nishioka, J. A. Ajani, and D. M. Ota. “Substituting ornithine for arginine in total parenteral nutrition eliminates enhanced tumor growth.” J Surg Oncol 50, no. 3 (July 1992): 161–67. https://doi.org/10.1002/jso.2930500307.
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  - Ellis, L. M., D. B. Evans, D. Martin, and D. M. Ota. “Laparoscopic feeding jejunostomy tube in oncology patients.” Surg Oncol 1, no. 3 (June 1992): 245–49. https://doi.org/10.1016/0960-7404(92)90071-r.
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  - Lippman, S. M., D. R. Parkinson, L. M. Itri, R. S. Weber, S. P. Schantz, D. M. Ota, M. A. Schusterman, I. H. Krakoff, J. U. Gutterman, and W. K. Hong. “13-cis-retinoic acid and interferon alpha-2a: effective combination therapy for advanced squamous cell carcinoma of the skin.” J Natl Cancer Inst 84, no. 4 (February 19, 1992): 235–41. https://doi.org/10.1093/jnci/84.4.235.
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  - Besa, P., T. A. Rich, L. Delclos, C. L. Edwards, D. M. Ota, and J. T. Wharton. “Extramammary Paget's disease of the perineal skin: role of radiotherapy.” Int J Radiat Oncol Biol Phys 24, no. 1 (1992): 73–78. https://doi.org/10.1016/0360-3016(92)91024-h.
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  - Ellis, L. M., and D. M. Ota. “Nutritional support of the critically ill cancer patient.” Cancer Bulletin 44, no. 3 (January 1, 1992): 234–43.
  - Ota, D. M., P. F. Mansfield, and J. A. Ajani. “Operative and adjuvant treatment strategies for gastric carcinoma.” Cancer Bulletin 44, no. 4 (January 1, 1992): 286–91.
  - Simmons, J. R., A. U. Buzdar, D. M. Ota, K. Marts, and G. N. Hortobagyi. “Complications associated with indwelling catheters.” Med Pediatr Oncol 20, no. 1 (1992): 22–25. https://doi.org/10.1002/mpo.2950200105.
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  - Grossie, V. B., D. M. Ota, J. A. Ajani, and K. Nishioka. “Amelioration of thrombocytopenia with concomitant ornithine in sarcoma-bearing rats receiving high dose difluoromethylornithine.” Invest New Drugs 9, no. 4 (November 1991): 321–26. https://doi.org/10.1007/BF00183572.
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  - McCready, D., R. Broadwater, M. Ross, R. Pollock, D. Ota, and C. Balch. “A case-control comparison of durability and cost between implanted reservoir and percutaneous catheters in cancer patients.” J Surg Res 51, no. 5 (November 1991): 377–81. https://doi.org/10.1016/0022-4804(91)90137-b.
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  - Irimura, T., D. M. Wynn, L. G. Hager, K. R. Cleary, and D. M. Ota. “Human colonic sulfomucin identified by a specific monoclonal antibody.” Cancer Res 51, no. 20 (October 15, 1991): 5728–35.
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  - Ajani, J. A., D. M. Ota, J. M. Jessup, F. C. Ames, C. McBride, A. Boddie, B. Levin, D. E. Jackson, M. Roh, and D. Hohn. “Resectable gastric carcinoma. An evaluation of preoperative and postoperative chemotherapy.” Cancer 68, no. 7 (October 1, 1991): 1501–6. https://doi.org/10.1002/1097-0142(19911001)68:7<1501::aid-cncr2820680706>3.0.co;2-l.
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  - Robey-Cafferty, S. S., J. A. Ajani, D. M. Ota, J. A. Roth, and J. M. Bruner. “Histologic observations and P-glycoprotein expression in gastric and esophageal adenocarcinomas treated with preoperative chemotherapy.” Arch Pathol Lab Med 115, no. 8 (August 1991): 807–12.
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  - Lotan, R., Y. Matsushita, D. Ohannesian, D. Carralero, D. M. Ota, K. R. Cleary, G. L. Nicolson, and T. Irimura. “Lactose-binding lectin expression in human colorectal carcinomas. Relation to tumor progression.” Carbohydr Res 213 (June 25, 1991): 47–57. https://doi.org/10.1016/s0008-6215(00)90597-4.
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  - Nishioka, K., V. B. Grossie, T. H. Chang, J. A. Ajani, and D. M. Ota. “Colorectal ornithine decarboxylase activity in human mucosa and tumors: elevation of enzymatic activity in distal mucosa.” J Surg Oncol 47, no. 2 (June 1991): 117–20. https://doi.org/10.1002/jso.2930470211.
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  - Matsushita, Y., S. D. Hoff, E. D. Nudelman, M. Otaka, S. Hakomori, D. M. Ota, K. R. Cleary, and T. Irimura. “Metastatic behavior and cell surface properties of HT-29 human colon carcinoma variant cells selected for their differential expression of sialyl-dimeric Le(x)-antigen.” Clin Exp Metastasis 9, no. 3 (May 1991): 283–99. https://doi.org/10.1007/BF01753731.
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  - Irimura, T., Y. Matsushita, S. D. Hoff, T. Yamori, S. Nakamori, M. L. Frazier, G. G. Giacco, K. R. Cleary, and D. M. Ota. “Ectopic expression of mucins in colorectal cancer metastasis.” Semin Cancer Biol 2, no. 2 (April 1991): 129–39.
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  - Ajani, J. A., D. M. Ota, and D. E. Jackson. “Current strategies in the management of locoregional and metastatic gastric carcinoma.” Cancer 67, no. 1 Suppl (January 1, 1991): 260–65. https://doi.org/10.1002/1097-0142(19910101)67:1+<260::aid-cncr2820671309>3.0.co;2-2.
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  - Irimura, T., Y. Matsushita, R. C. Sutton, D. Carralero, D. W. Ohannesian, K. R. Cleary, D. M. Ota, G. L. Nicolson, and R. Lotan. “Increased content of an endogenous lactose-binding lectin in human colorectal carcinoma progressed to metastatic stages.” Cancer Res 51, no. 1 (January 1, 1991): 387–93.
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  - Broadwater, J. R., M. A. Henderson, J. L. Bell, M. J. Edwards, G. J. Smith, D. R. McCready, R. S. Swanson, M. E. Hardy, R. R. Shenk, and M. Lawson. “Outpatient percutaneous central venous access in cancer patients.” Am J Surg 160, no. 6 (December 1990): 676–80. https://doi.org/10.1016/s0002-9610(05)80773-1.
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  - Matsushita, Y., K. R. Cleary, D. M. Ota, S. D. Hoff, and T. Irimura. “Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases.” Lab Invest 63, no. 6 (December 1990): 780–91.
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  - Irimura, T., A. M. McIsaac, D. A. Carlson, M. Yagita, E. A. Grimm, D. G. Menter, D. M. Ota, and K. R. Clary. “Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.” Cancer Res 50, no. 11 (June 1, 1990): 3331–38.
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  - Hoff, S. D., T. Irimura, Y. Matsushita, D. M. Ota, K. R. Cleary, and S. Hakomori. “Metastatic potential of colon carcinoma. Expression of ABO/Lewis-related antigens.” Arch Surg 125, no. 2 (February 1990): 206–9. https://doi.org/10.1001/archsurg.1990.01410140084013.
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  - Ajani, J. A., D. M. Ota, V. B. Grossie, J. L. Abbruzzese, J. S. Faintuch, Y. Z. Patt, D. E. Jackson, B. Levin, and K. Nishioka. “Evaluation of continuous-infusion alpha-difluoromethylornithine therapy for colorectal carcinoma.” Cancer Chemother Pharmacol 26, no. 3 (1990): 223–26. https://doi.org/10.1007/BF02897204.
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  - Hoff, S. D., Y. Matsushita, D. M. Ota, K. R. Cleary, T. Yamori, S. Hakomori, and T. Irimura. “Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma.” Cancer Res 49, no. 24 Pt 1 (December 15, 1989): 6883–88.
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  - Grossie, V. B., K. Nishioka, T. H. Chang, D. Patenia, M. M. Benitez, J. A. Ajani, and D. M. Ota. “Differential effects of parenteral nutrition on tumor growth and erythrocyte polyamine levels in the rat.” Jpen J Parenter Enteral Nutr 13, no. 6 (November 1989): 590–95. https://doi.org/10.1177/0148607189013006590.
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  - Ajani, J. A., D. M. Ota, V. B. Grossie, B. Levin, and K. Nishioka. “Alterations in polyamine metabolism during continuous intravenous infusion of alpha-difluoromethylornithine showing correlation of thrombocytopenia with alpha-difluoromethylornithine plasma levels.” Cancer Res 49, no. 20 (October 15, 1989): 5761–65.
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  - Kroll, S. S., R. Pollock, J. M. Jessup, and D. Ota. “Transpelvic rectus abdominis flap reconstruction of defects following abdominal-perineal resection.” Am Surg 55, no. 10 (October 1989): 632–37.
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  - Grossie, V. B., D. M. Ota, J. A. Ajani, T. H. Chang, D. Patenia, and K. Nishioka. “Reduction of difluoromethylornithine-induced thrombocytopenia in rats with ornithine while maintaining antitumor activity.” Cancer Res 49, no. 15 (August 1, 1989): 4159–62.
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  - Yamori, T., D. M. Ota, K. R. Cleary, S. Hoff, L. G. Hager, and T. Irimura. “Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases.” Cancer Res 49, no. 4 (February 15, 1989): 887–94.
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  - Jackson, G. L., S. Pathak, L. A. Jones, V. Vogel, K. I. Kemp, D. M. Ota, P. Kulkarni, S. Vernon, P. Conoley, and V. Hopwood. “Breast cancer screening-individualized risk assessment and application of new research technology: non-protein bound estradiol and chromosome analysis.” Prog Clin Biol Res 293 (1989): 271–78.
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  - McCready, D. R., D. M. Ota, T. A. Rich, D. Thielvoldt, and J. M. Jessup. “Prospective phase I trial of conservative management of low rectal lesions.” Arch Surg 124, no. 1 (January 1989): 67–70. https://doi.org/10.1001/archsurg.1989.01410010077016.
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  - Rich, T. A., L. L. Hughes, J. M. Jessup, D. M. Ota, F. C. Ames, D. C. Hohn, R. G. Martin, J. A. Ajani, and J. L. Abbruzzese. “Conservative management of anal and low rectal cancers with combined modality therapy.” Cancer Bulletin 41, no. 2 (January 1, 1989): 71–74.
  - Nishioka, K., V. B. Grossie, J. A. Ajani, D. Patenia, T. H. Chang, and D. M. Ota. “Polyamine-directed preferential nutritional repletion of normal tissues in tumor-bearing hosts.” Int J Cancer 42, no. 5 (November 15, 1988): 744–47. https://doi.org/10.1002/ijc.2910420520.
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  - Grossie, V. B., D. M. Ota, J. A. Ajani, T. H. Chang, D. Patenia, and K. Nishioka. “Influence of total parenteral nutrition on tumor growth and polyamine biosynthesis of fibrosarcoma-bearing rats after induced cachexia.” Jpen J Parenter Enteral Nutr 12, no. 5 (September 1988): 441–44. https://doi.org/10.1177/0148607188012005441.
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  - Irimura, T., D. A. Carlson, J. Price, T. Yamori, R. Giavazzi, D. M. Ota, and K. R. Cleary. “Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues.” Cancer Res 48, no. 9 (May 1, 1988): 2353–60.
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  - Irimura, T., D. A. Carlson, and D. M. Ota. “Electrophoretic analysis of four high molecular weight sialoglycoproteins produced by metastatic human colon carcinoma cells.” J Cell Biochem 37, no. 1 (May 1988): 1–9. https://doi.org/10.1002/jcb.240370102.
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  - Yamori, T., D. M. Ota, K. R. Cleary, and T. Irimura. “Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody.” J Cell Biochem 36, no. 4 (April 1988): 405–16. https://doi.org/10.1002/jcb.240360409.
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  - Irimura, T., M. Nakajima, T. Yamori, D. M. Ota, K. F. Cleary, and G. L. Nicolson. “Glycoconjugates and tumor metastasis.” Adv Exp Med Biol 228 (1988): 677–704. https://doi.org/10.1007/978-1-4613-1663-3_27.
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  - Dimery, I. W., K. Nishioka, V. B. Grossie, D. M. Ota, S. P. Schantz, R. Byers, K. T. Robbins, and W. K. Hong. “Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.” Am J Surg 154, no. 4 (October 1987): 429–33. https://doi.org/10.1016/0002-9610(89)90018-4.
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  - Jones, L. A., D. M. Ota, G. A. Jackson, P. M. Jackson, K. Kemp, D. E. Anderson, S. K. McCamant, and D. H. Bauman. “Bioavailability of estradiol as a marker for breast cancer risk assessment.” Cancer Res 47, no. 19 (October 1, 1987): 5224–29.
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  - Irimura, T., T. Yamori, S. C. Bennett, D. M. Ota, and K. R. Cleary. “The relationship of collagenolytic activity to stage of human colorectal carcinoma.” Int J Cancer 40, no. 1 (July 15, 1987): 24–31. https://doi.org/10.1002/ijc.2910400106.
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  - Yamori, T., H. Kimura, K. Stewart, D. M. Ota, K. R. Cleary, and T. Irimura. “Differential production of high molecular weight sulfated glycoproteins in normal colonic mucosa, primary colon carcinoma, and metastases.” Cancer Res 47, no. 10 (May 15, 1987): 2741–47.
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  - Grossie, V. B., D. M. Ota, J. A. Ajani, and K. Nishioka. “Effect of intravenous alpha-difluoromethylornithine on the polyamine levels of normal tissue and a transplantable fibrosarcoma.” Cancer Res 47, no. 7 (April 1, 1987): 1836–40.
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  - Irimura, T., D. M. Ota, and K. R. Cleary. “Ulex europeus agglutinin I-reactive high molecular weight glycoproteins of adenocarcinoma of distal colon and rectum and their possible relationship with metastatic potential.” Cancer Res 47, no. 3 (February 1, 1987): 881–89.
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  - Jones, L. A., D. M. Ota, G. A. Jackson, P. M. Jackson, K. Kemp, D. E. Anderson, S. K. McCamant, and D. H. Bauman. “Bioavailability of Estradiol as a Marker for Breast Cancer Risk Assessment.” Cancer Research 47, no. 19 (January 1, 1987): 5092–5140.
  - Ota, D. M., V. B. Grossie, J. A. Ajani, L. C. Stephens, and K. Nishioka. “Red blood cell polyamine levels and host toxicity during continuous alpha-difluoromethylornithine infusion.” Int J Cancer 38, no. 2 (August 15, 1986): 245–49. https://doi.org/10.1002/ijc.2910380215.
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  - Grossie, V. B., K. Nishioka, D. M. Ota, and R. G. Martin. “Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats.” Cancer Res 46, no. 7 (July 1986): 3464–68.
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  - Ota, D. M., G. Kleman, and K. Diamond. “Practical considerations in the nutritional management of the cancer patient.” Curr Probl Cancer 10, no. 7 (July 1986): 345–98. https://doi.org/10.1016/s0147-0272(86)80013-7.
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  - Ota, D. M., K. Nishioka, B. Grossie, and D. Dixon. “Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma.” Eur J Cancer Clin Oncol 22, no. 7 (July 1986): 837–42. https://doi.org/10.1016/0277-5379(86)90371-8.
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  - Ota, D. M., L. A. Jones, G. L. Jackson, P. M. Jackson, K. Kemp, and D. Bauman. “Obesity, non-protein-bound estradiol levels, and distribution of estradiol in the sera of breast cancer patients.” Cancer 57, no. 3 (February 1, 1986): 558–62. https://doi.org/10.1002/1097-0142(19860201)57:3<558::aid-cncr2820570326>3.0.co;2-1.
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  - Grossie, V. B., K. Nishioka, and D. M. Ota. “Ornithine decarboxylase activity of normal tissue from tumor-bearing rats.” Journal of Nutrition Growth and Cancer 3, no. 1 (January 1, 1986): 41–46.
  - Jackson, P. M., G. L. Jackson, K. Kemp, D. H. Bauman, D. M. Ota, and L. A. Jones. “Development of a breast cancer screening & research program.” Prog Clin Biol Res 216 (1986): 71–78.
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  - Jessup, J. M., C. M. McBride, F. C. Ames, L. Guarda, D. M. Ota, M. M. Romsdahl, and R. G. Martin. “Active specific immunotherapy of Dukes B2 and C colorectal carcinoma: comparison of two doses of the vaccine.” Cancer Immunol Immunother 21, no. 3 (1986): 233–39. https://doi.org/10.1007/BF00199367.
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  - Miller, W., D. Ota, G. Giacco, V. Guinee, T. Irimura, G. Nicolson, and K. Cleary. “Absence of a relationship of size of primary colon carcinoma with metastasis and survival.” Clin Exp Metastasis 3, no. 3 (July 1985): 189–96. https://doi.org/10.1007/BF01786762.
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  - Ota, D. M., P. Frasier, J. Guevara, and M. Foulkes. “Plasma proteins as indices of response to nutritional therapy in cancer patients.” J Surg Oncol 29, no. 3 (July 1985): 160–65. https://doi.org/10.1002/jso.2930290306.
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  - Ota, D., L. Alvarez, B. Lichtiger, G. Giacco, and V. Guinee. “Perioperative blood transfusion in patients with colon carcinoma.” Transfusion 25, no. 4 (July 1985): 392–94. https://doi.org/10.1046/j.1537-2995.1985.25485273825.x.
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  - Harris, W. B., V. B. Grossie, D. M. Ota, K. Nishioka, J. A. Ajani, T. Chang, and D. Patenia. “Effect of difluoromethylornithine on host and tumor polyamine metabolism during total parenteral nutrition.” J Surg Res 38, no. 6 (June 1985): 592–98. https://doi.org/10.1016/0022-4804(85)90080-0.
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  - Ota, D. M., and B. Drewinko. “Growth kinetics of human colorectal carcinoma.” Cancer Res 45, no. 5 (May 1985): 2128–31.
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  - Ota, D. M., J. M. Jessup, G. F. Babcock, L. Kirschbaum, C. F. Mountain, M. J. McMurtrey, and E. M. Copeland. “Immune function during intravenous administration of a soybean oil emulsion.” Jpen J Parenter Enteral Nutr 9, no. 1 (January 1985): 23–27. https://doi.org/10.1177/014860718500900123.
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  - Pollock, R. E., F. C. Ames, D. M. Ota, and P. Mansell. “A surgical oncology perspective on AIDS.” Semin Surg Oncol 1, no. 3 (1985): 153–60. https://doi.org/10.1002/ssu.2980010306.
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  - Ota, D. M., K. Nishioka, M. Foulkes, and V. B. Grossie. “Nutritional parameters affecting erythrocyte polyamine levels in cancer patients.” J Clin Oncol 2, no. 10 (October 1984): 1157–64. https://doi.org/10.1200/JCO.1984.2.10.1157.
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  - Copeland, E. M., D. M. Ota, and L. C. Cox. “Hyperalimentation and oncologic management: update.” Compr Ther 9, no. 11 (November 1983): 64–69.
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  - Floyd, C. M., D. Ota, J. Corriere, S. J. Dudrick, and E. M. Copeland. “Effect of serum source on protein-free diet lymphocyte blastogenesis.” The Journal of Surgical Research 35, no. 3 (September 1983): 243–48. https://doi.org/10.1016/s0022-4804(83)80010-9.
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  - Grossie, V. B., C. E. Castro, and D. M. Ota. “Modification of polycarbonate cages for individual housing of mice.” Lab Anim Sci 33, no. 4 (August 1983): 365.
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  - OTA, D. M., and E. M. COPELAND. “GASTROINTESTINAL CANCER .5. NUTRITIONAL THERAPY IN CANCER-PATIENTS.” Practical Gastroenterology 6, no. 2 (January 1, 1982): 9–12.
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  - Dudrick, S. J., E. M. Copeland, J. M. Daly, J. M. Long, J. H. Duke, B. V. MacFadyen, B. J. Rowlands, et al. “A clinical review of nutritional support of the patient.” Jpen J Parenter Enteral Nutr 3, no. 6 (November 1979): 444–51. https://doi.org/10.1177/014860717900300608.
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  - Copeland, E. M., J. M. Daly, D. M. Ota, and S. J. Dudrick. “Nutrition, cancer, and intravenous hyperalimentation.” Cancer 43, no. 5 Suppl (May 1979): 2108–16. https://doi.org/10.1002/1097-0142(197905)43:5+<2108::aid-cncr2820430720>3.0.co;2-6.
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  - Floyd, C., D. Ota, J. N. Corriere, S. J. Dudrick, and E. M. Copeland. “Effect of protein depletion on serum factors for lymphocyte transformation.” Surg Forum 30 (1979): 57–60.
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  - Ota, D. M., E. M. Copeland, J. N. Corriere, and S. J. Dudrick. “The effects of nutrition and treatment of cancer on host immunocompetence.” Surg Gynecol Obstet 148, no. 1 (January 1979): 104–11.
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  - Ota, D. M., A. L. Imbembo, and G. D. Zuidema. “Total parenteral nutrition.” Surgery 83, no. 5 (May 1978): 503–20.
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  - Ota, D. M., E. M. Copeland, J. N. Corriere, E. R. Richie, K. Jacobson, and S. J. Dudrick. “The effects of a 10% soybean oil emulsion on lymphocyte transformation.” Jpen J Parenter Enteral Nutr 2, no. 2 (May 1978): 112–15. https://doi.org/10.1177/014860717800200205.
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  - Ota, D. M., E. M. Copeland, H. W. Strobel, J. Daly, E. T. Gum, E. Guinn, and S. J. Dudrick. “The effect of protein nutrition on host and tumor metabolism.” J Surg Res 22, no. 3 (March 1977): 181–88. https://doi.org/10.1016/0022-4804(77)90132-9.
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  - Ota, D. M., E. M. Copeland, J. N. Corriere, K. A. Jacobson, and S. J. Dudrick. “Effects of protein nutrition on lymphocyte transformation.” Surg Forum 28 (1977): 65–66.
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  - Ota, D. M. “The use of histidase for the study of amniotic cell origin and histidinemia.” Am J Obstet Gynecol 117, no. 4 (October 15, 1973): 567–71. https://doi.org/10.1016/0002-9378(73)90123-3.
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- Other Articles
  - Ota, David M., Heidi Nelson, and Armando Giuliano. “Node biopsy vs. full lymph node dissection for breast cancer.” Bull Am Coll Surg, October 2010.
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  - Ota, David M., and Heidi Nelson. “Changing multidisciplinary cancer treatment through ACOSOG trials.” Bull Am Coll Surg, April 2010.
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  - Wilke, Lee Gravatt, Heidi Nelson, and David M. Ota. “Promoting patient safety through peer review.” Bull Am Coll Surg, March 2010.
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  - Nelson, Heidi, and David Ota. “Promoting patient safety.” Bull Am Coll Surg, December 2009.
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  - You, Y Nancy, David Ota, and Heidi Nelson. “The American College of Surgeons Oncology Group.” Surgery, June 2009. https://doi.org/10.1016/j.surg.2009.03.009.
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  - Lind, D. S., N. P. Schaub, M. Hawkins, K. W. Sharp, D. Ota, and K. Bland. “Discussion.” American Surgeon, August 1, 2008.
  - Ota, David, and Heidi Nelson. “A phase II trial for minimally invasive esophagectomy.” Bull Am Coll Surg, February 2008.
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  - Ota, David M., Heidi Nelson, and Heidi ACOSOG Group Co-Chairs. “Local excision of rectal cancer revisited: ACOSOG protocol Z6041.” Ann Surg Oncol, February 2007. https://doi.org/10.1245/s10434-006-9213-7.
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  - Ota, David, and Heidi Nelson. “The surgeon and adjuvant therapy for stage II colon cancer.” Ann Surg Oncol, February 2007. https://doi.org/10.1245/s10434-006-9161-2.
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  - Ota, D. M., and H. Nelson. “Coin of the realm.” Annals of Surgical Oncology, July 1, 2006. https://doi.org/10.1245/ASO.2006.04.0236.
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  - Ota, D. M. “A pilot study of preoperative chemoradiation for gastric cancer.” Ann Surg Oncol, July 2001. https://doi.org/10.1007/s10434-001-0482-x.
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  - Ota, D. M. “The Wexner/Hwang article reviewed.” Oncology, December 1, 2000.
  - Pestieau, S. R., and P. H. Sugarbaker. “Treatment of primary colon cancer with peritoneal carcinomatosis: comparison of concomitant vs. delayed management.” Dis Colon Rectum, October 2000. https://doi.org/10.1007/BF02236627.
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  - Ota, D. M. “Is intraoperative lymph node mapping and sentinel lymph node biopsy for colorectal carcinoma necessary?” Ann Surg Oncol, March 2000. https://doi.org/10.1007/s10434-000-0082-1.
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  - Ota, D. M. “Myocutaneous pedicle flaps after abdomino-perineal resection for recurrent rectal cancer.” Ann Surg Oncol, January 1999. https://doi.org/10.1007/s10434-999-0003-x.
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  - Boddie, A. W., A. W. Mahvi, D. M. Ota, R. A. Prinz, and J. Pickleman. “Perivascular and intralesional tissue necrosis after hepatic cryoablation: Results in a porcine model - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1997.
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  - Dawes, L. G., L. G. Liu, G. M. Fried, and D. M. Ota. “Carcinoma involving the gallbladder in elderly patients presenting with acute cholecystitis - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1997.
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  - DeBord, J. R., R. B. Arenas, B. A. Harms, and D. M. Ota. “Incidence and therapeutic implications of synchronous colonic pathology in colorectal adenocarcinoma - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1997.
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  - Harms, B. A., S. B. Archer, D. M. Ota, T. A. Stellato, R. M. Zollinger, N. C. Estes, and A. Senagore. “Implementation of a clinical pathway decreases length of stay and hospital charges for patients undergoing total colectomy and ileal pouch anal anastomosis - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1997.
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  - Sarr, M. G., P. Iannoli, J. S. Thompson, and D. M. Ota. “Epidermal growth factor and human growth hormone accelerate adaptation after massive enterectomy in an additive, nutrient-dependent, and site-specific fashion - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1997.
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  - Ota, D. M. “Preoperative radiotherapy for rectal cancer: benefits and controversies.” Ann Surg Oncol, September 1996. https://doi.org/10.1007/BF02305757.
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  - Ota, D. M. “Laparoscopic colectomy for cancer: a favorable opinion.” Ann Surg Oncol, January 1995. https://doi.org/10.1007/BF02303695.
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  - Ota, D. M., and D. B. Evans. “Feeding jejunostomy techniques.” Surgery, May 1993.
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- Conference Papers
  - Ellis, Matthew James, Li Ding, Dong Shen, Jingqin Luo, Vera J. Suman, Reece J. Goiffon, John W. Wallis, et al. “Whole genome sequencing to characterize luminal-type breast cancer.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.
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  - Chan, E., Q. Shi, J. Garcia-Aguilar, B. G. Wolff, C. S. Johnson, B. Sanders, X. Carrero, M. C. Posner, D. M. Ota, and C. R. Thomas. “Chemoradiation (CRT) Safety Analysis of ACOSOG Z6041: A Phase II Trial of Neoadjuvant (NEO) CRT followed by Local Excision (LE) in uT2 Rectal Cancer (RC).” In International Journal of Radiation Oncology*Biology*Physics, 78:S53–54. Elsevier BV, 2010. https://doi.org/10.1016/j.ijrobp.2010.07.159.
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  - Brenner, B. M., W. Vandewalle, R. A. Komorowski, and D. M. Ota. “The onset of genomic instability in sporadic colorectal polyps.” In Annals of Surgical Oncology, 11:S85–86. Springer Science and Business Media LLC, 2004. https://doi.org/10.1007/bf02524074.
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  - Jacobs, L. K., B. W. Kuvshinoff, K. M. Lin, M. P. Watson, and D. M. Ota. “Preoperative 5-FU and radiation therapy increases sphincter preservation rates and improves R0 resection rates for rectal cancer.” In Annals of Surgical Oncology, 9:S73–S73. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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  - Lin, K. M., J. Greer, C. Ridpath, M. Miller, L. Jacobs, B. Kuvshinoff, and D. M. Ota. “Incidence of invasive breast cancer following initial diagnosis of nonpalpable ductal carcinoma in-situ by stereotactic core needle biopsy.” In Annals of Surgical Oncology, 9:S57–S57. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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  - Miller, M. L., K. Lin, L. Jacobs, B. Kuvshinoff, T. Loy, F. Rodriguez, M. Watson, and D. M. Ota. “Pathologic features affecting detection of metastasis in breast cancer sentinel lymph nodes during intraoperative frozen section analysis.” In Annals of Surgical Oncology, 9:S60–S60. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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  - Kuvshinoff, B. W., I. Magfoor, B. Miedema, J. Wilkes, S. Westgate, and D. M. Ota. “Preoperative chemoradiotherapy permits <1 CM distal margin and sphincter preservation for distal rectal cancer.” In Gastroenterology, 114:A1403–A1403. Elsevier BV, 1998. https://doi.org/10.1016/s0016-5085(98)85703-x.
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  - Feig, B. W., C. A. Staley, P. F. Mansfield, L. M. Ellis, J. M. Skibber, A. Madary, and D. M. Ota. “The efficacy of laparoscopic colon resection for cancer.” In Gastroenterology, 110:A1383–A1383. W B SAUNDERS CO-ELSEVIER INC, 1996.
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  - FEIG, B. W., D. H. BERGER, J. F. DUPUIS, T. B. DOUGHERTY, D. A. JOHNSTON, R. J. GROSS, and D. M. OTA. “HEMODYNAMIC-EFFECTS OF CO2 ABDOMINAL INSUFFLATION (CAI) DURING LAPAROSCOPY IN HIGH-RISK PATIENTS.” In Anesthesia and Analgesia, 78:U68–U68. WILLIAMS & WILKINS, 1994.
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  - FEIG, B. W., D. H. BERGER, T. B. DOUGHERTY, J. F. DUPUIS, D. A. JOHNSTON, R. J. GROSS, and D. M. OTA. “PULMONARY EFFECTS OF CO2 ABDOMINAL INSUFFLATION (CAI) DURING LAPAROSCOPY IN HIGH-RISK PATIENTS.” In Anesthesia and Analgesia, 78:U67–U67. WILLIAMS & WILKINS, 1994.
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  - Weinstein, Geoffrey D., Tyvin A. Rich, Charles R. Shumate, John M. Skibber, Jaffer A. Ajani, and David M. Ota. “Preoperative chemoradiation and complete surgical excision with or without intraoperative electron beam boost (EB-IORT) for advanced primary rectal cancer.” In International Journal of Radiation Oncology*Biology*Physics, 27:277–277. Elsevier BV, 1993. https://doi.org/10.1016/0360-3016(93)90873-t.
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  - NISHIOKA, K., V. B. GROSSIE, T. H. CHANG, J. A. AJANI, and D. M. OTA. “COLORECTAL ORNITHINE DECARBOXYLASE ACTIVITY IN HUMAN MUCOSA AND TUMORS - ELEVATION OF ENZYMATIC-ACTIVITY IN DISTAL MUCOSA - POSTER.” In Polyamines in the Gastrointestinal Tract, edited by R. H. DOWLING, U. R. FOLSCH, and C. LOSER, 62:522–522. KLUWER ACADEMIC PUBL, 1992.
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  - GROSSIE, V. B., K. NISHIOKA, R. MEDLEY, J. A. AJANI, and D. M. OTA. “ROLE OF ARGININE IN TOTAL PARENTERAL-NUTRITION (TPN)-ENHANCED TUMOR-GROWTH IN THE RAT.” In Faseb Journal, 2:A860–A860. FEDERATION AMER SOC EXP BIOL, 1988.
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  - GROSSIE, V. B., D. M. OTA, J. A. AJANI, and K. NISHIOKA. “MODULATION OF DIFLUOROMETHYLORNITHINE TOXICITY BY CONCOMITANT ORNITHINE TREATMENT IN TUMOR-BEARING RATS.” In Proceedings of the American Association for Cancer Research, 29:346–346. AMER ASSOC CANCER RESEARCH, 1988.
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  - IRIMURA, T., D. A. CARLSON, M. YAGITA, E. A. GRIMM, and D. M. OTA. “INCREASED EXPRESSION OF COLON-CARCINOMA SIALOMUCIN INDUCED BY NORMAL TISSUE FACTORS AND ITS ASSOCIATION WITH IMMUNE EFFECTOR RESISTANCE.” In Proceedings of the American Association for Cancer Research, 29:400–400. AMER ASSOC CANCER RESEARCH, 1988.
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  - YAMORI, T., T. IRIMURA, D. M. OTA, K. R. CLEARY, and S. HOFF. “DETECTION OF SULFOMUCIN EXPRESSION IN COLONIC MUCOSA, PRIMARY COLON-CARCINOMA AND METASTASES USING A SPECIFIC MONOCLONAL-ANTIBODY (91.9H).” In Proceedings of the American Association for Cancer Research, 29:63–63. AMER ASSOC CANCER RESEARCH, 1988.
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  - IRIMURA, T., D. A. CARLSON, M. YAGITA, E. A. GRIMM, and D. M. OTA. “COLON-CARCINOMA SIALOMUCIN PRODUCTION STIMULATED BY MUCOMODULIN AND ASSOCIATION WITH INCREASED IMMUNE EFFECTOR RESISTANCE.” In Glycoconjugate Journal, 5:300–300. CHAPMAN HALL LTD, 1988.
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  - MATSUSHITA, Y., S. HOFF, D. M. OTA, K. R. CLEARY, and T. IRIMURA. “SIALYL DIMERIC-LEWIS-X ANTIGEN EXPRESSED ON MUCIN-LIKE GLYCOPROTEINS IN COLON CANCER METASTASIS.” In Glycoconjugate Journal, 5:322–322. CHAPMAN HALL LTD, 1988.
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  - YAMORI, T., L. HAGER, H. KIMURA, D. M. OTA, K. R. CLEARY, and T. IRIMURA. “HUMAN COLONIC SULFOMUCIN AND AN ANTI-SULFOMUCIN MONOCLONAL-ANTIBODY.” In Glycoconjugate Journal, 5:322–322. CHAPMAN HALL LTD, 1988.
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  - GROSSIE, V. B., D. M. OTA, J. A. AJANI, and K. NISHIOKA. “DIFFERENTIAL EFFECT OF DIFLUOROMETHYLORNITHINE (DFMO) ON HEPATIC AND TUMOR POLYAMINE METABOLISM IN SARCOMA-BEARING RATS.” In Proceedings of the American Association for Cancer Research, 28:319–319. AMER ASSOC CANCER RESEARCH, 1987.
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  - IRIMURA, T., J. E. HESTER, T. YAMORI, P. N. BELLONI, I. J. FIDLER, D. M. OTA, and G. L. NICOLSON. “ADHESIVE PROPERTIES OF HUMAN-COLON CARCINOMA-CELLS ESTABLISHED FROM PRIMARY TUMOR AND METASTASES.” In Proceedings of the American Association for Cancer Research, 28:73–73. AMER ASSOC CANCER RESEARCH, 1987.
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  - NISHIOKA, K., V. B. GROSSIE, D. M. OTA, and J. A. AJANI. “POLYAMINE DIRECTED PREFERENTIAL NUTRITIONAL REPLETION OF NORMAL-TISSUES IN TUMOR-BEARING HOSTS.” In Proceedings of the American Association for Cancer Research, 28:317–317. AMER ASSOC CANCER RESEARCH, 1987.
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  - YAMORI, T., H. KIMURA, K. STEWART, D. M. OTA, K. R. CLEARY, and T. IRIMURA. “DIFFERENTIAL PRODUCTION OF HIGH-MOLECULAR-WEIGHT SULFATED GLYCOPROTEINS IN NORMAL COLONIC MUCOSA, PRIMARY COLON-CARCINOMA, AND METASTASIS.” In Journal of Cellular Biochemistry, 115–115. WILEY-LISS, 1987.
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  - GROSSIE, V. B., D. M. OTA, L. C. STEPHENS, J. AJANI, and K. NISHIOKA. “ANTITUMOR-ACTIVITY AND HOST TOXICITY OF CONTINUOUS INTRAVENOUS (IV) ALPHA-DIFLUOROMETHYLORNITHINE (DFMO).” In Proceedings of the American Association for Cancer Research, 27:292–292. AMER ASSOC CANCER RESEARCH, 1986.
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  - IRIMURA, T., S. C. BENNETT, T. YAMORI, D. M. OTA, and K. R. CLEARY. “COLLAGENOLYTIC ACTIVITIES OF HUMAN COLORECTAL-CARCINOMA AT DIFFERENT STAGES.” In Proceedings of the American Association for Cancer Research, 27:58–58. AMER ASSOC CANCER RESEARCH, 1986.
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  - IRIMURA, T., T. YAMORI, K. STEWERT, S. C. BENNETT, D. M. OTA, K. R. CLEARY, and I. J. FIDLER. “CELL-SURFACE GLYCOCONJUGATES OF HUMAN COLORECTAL-CARCINOMA WITH DIFFERENT METASTATIC POTENTIALS.” In Federation Proceedings, 45:686–686. FEDERATION AMER SOC EXP BIOL, 1986.
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  - YAMORI, T., T. IRIMURA, D. M. OTA, K. R. CLEARY, R. GIAVAZZI, and I. J. FIDLER. “SULFATED GLYCOCONJUGATES PRODUCED BY HUMAN-COLON CARCINOMA CELL-LINES WITH DIFFERENT METASTATIC POTENTIALS.” In Proceedings of the American Association for Cancer Research, 27:63–63. AMER ASSOC CANCER RESEARCH, 1986.
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  - Harris, W., D. Ota, and B. Grossie. “Monitoring difluoromethyl ornithine(DFMO) inhibition of tumor polyamine(PA) synthesis.” In Proceedings of the American Association for Cancer Research, Vol. VOL. 26, 1985.
  - IRIMURA, T., D. M. OTA, K. R. CLEARY, and G. L. NICOLSON. “GLYCOPROTEIN ANALYSIS OF HUMAN RECTUM AND SIGMOID COLON CARCINOMAS AT VARIOUS STAGES OF METASTASES USING LECTINS.” In Proceedings of the American Association for Cancer Research, 26:49–49. AMER ASSOC CANCER RESEARCH, 1985.
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  - Irimura, T., D. M. Ota, K. R. Cleary, and G. L. Nicolson. “Glycoprotein analysis of human rectum and Sigmoid colon carcinomas at various stages of metastases using lectins.” In Proceedings of the American Association for Cancer Research, Vol. VOL. 26, 1985.
  - JONES, L. A., D. M. OTA, D. E. ANDERSON, G. L. JACKSON, P. M. JACKSON, K. KEMP, and D. H. BAUMAN. “PERCENT DISTRIBUTION OF ESTRADIOL (E2) IN SERA OF WOMEN WITH BREAST-CANCER (BCA) AND DISEASE-FREE WOMEN WITH (FHCA) AND WITHOUT (NOFHCA) A FAMILY HISTORY OF BREAST-CANCER.” In Proceedings of the American Association for Cancer Research, 26:197–197. AMER ASSOC CANCER RESEARCH, 1985.
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  - JONES, L. A., D. M. OTA, G. A. JACKSON, K. KEMP, and D. H. BAUMAN. “PERCENT-NON-PROTEIN BOUND (NPBE) AND PERCENT-ALBUMIN BOUND (ABE) ESTRADIOL AS A POSSIBLE BIOMARKER FOR BREAST-CANCER (BCA).” In Breast Cancer Research and Treatment, 6:180–180. KLUWER ACADEMIC PUBL, 1985.
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  - Jones, L. A., D. M. Ota, and D. E. Anderson. “Distribution of estradiol (E2) in sera of women with breast cancer (BCa) and disease-free women with (FHCa) and without (NoFHCa). A family history of breast cancer.” In Proceedings of the American Association for Cancer Research, Vol. VOL. 26, 1985.
  - GROSSIE, V. B., K. NISHIOKA, and D. M. OTA. “NUTRITIONAL-STATUS AND ERYTHROCYTE (RBC) POLYAMINES (PA) LEVELS IN FIBRO-SARCOMA BEARING RATS.” In Proceedings of the American Association for Cancer Research, 25:51–51. AMER ASSOC CANCER RESEARCH, 1984.
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  - OTA, D. M., J. M. JESSUP, G. F. BABCOCK, L. KIRSCHBAUM, C. F. MOUNTAIN, M. J. MCMURTREY, and E. M. COPELAND. “IMMUNE FUNCTION DURING SOYBEAN OIL EMULSION INFUSION.” In Journal of Parenteral and Enteral Nutrition, 8:84–84. AMER SOC PARENTERAL & ENTERAL NUTRITION, 1984.
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  - GROSSIE, V. B., D. M. OTA, R. G. SMITH, and T. L. LOO. “NUTRITIONAL-STATUS AND ANTI-TUMOR ACTIVITY OF CYCLOPHOSPHAMIDE (CP) AGAINST L1210 LEUKEMIA.” In Proceedings of the American Association for Cancer Research, 24:307–307. AMER ASSOC CANCER RESEARCH, 1983.
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  - DUDRICK, S. J., B. J. ROWLANDS, A. M. SPEIR, D. M. OTA, A. C. HENRY, D. M. ENGLERT, and C. W. COLEMAN. “INTRAVENOUS HYPERALIMENTATION (IVH) AS THE SOLE TREATMENT FOR ANEMIA AND ULCERATIVE-COLITIS (UC) IN 2 JEHOVAHS-WITNESSES.” In Federation Proceedings, 39:1114–1114. FEDERATION AMER SOC EXP BIOL, 1980.
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  - OTA, D. M., E. M. COPELAND, J. N. CORRIERE, E. R. RICHIE, K. A. JACOBSON, and S. J. DUDRICK. “EFFECTS OF INTRALIPID ON LYMPHOCYTE-TRANSFORMATION.” In Federation Proceedings, 36:1218–1218, 1977.
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  - Ota, D. M., E. M. Copeland, and J. N. Corriere. “Effects of intralipid on lymphocyte transformation.” In Federation Proceedings, Vol. 36, 1977.

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