Current Appointments & Affiliations
Professor of Surgery
·
2006 - Present
Surgical Oncology,
Surgery
Recent Publications
Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial.
Journal Article Ann Oncol · May 1, 2017 BACKGROUND: HER2 (ERBB2) gene amplification and its corresponding overexpression are present in 15-30% of invasive breast cancers. While HER2-targeted agents are effective treatments, resistance remains a major cause of death. The American College of Surge ... Full text Link to item CiteKi67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Journal Article J Clin Oncol · April 1, 2017 Purpose To determine the pathologic complete response (pCR) rate in estrogen receptor (ER) -positive primary breast cancer triaged to chemotherapy when the protein encoded by the MKI67 gene (Ki67) level was > 10% after 2 to 4 weeks of neoadjuvant aromatase ... Full text Link to item CiteComprehensive genomic studies: emerging regulatory, strategic, and quality assurance challenges for biorepositories.
Journal Article Am J Clin Pathol · July 2012 As part of the molecular revolution sweeping medicine, comprehensive genomic studies are adding powerful dimensions to medical research. However, their power exposes new regulatory, strategic, and quality assurance challenges for biorepositories. A key iss ... Full text Link to item CiteRecent Grants
Support for Specimen Banking in ACOSOG GY 6
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2012ACOSOG Competing Renewal
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2011ACOSOG Supplemental Z1072
Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2010View All Grants
Education, Training & Certifications
The University of Chicago ·
1973
M.D.