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Engineering microbial systems to explore ecological and evolutionary dynamics.

Publication ,  Journal Article
Tanouchi, Y; Smith, RP; You, L
Published in: Current opinion in biotechnology
October 2012

A major goal of biological research is to provide a mechanistic understanding of diverse biological processes. To this end, synthetic biology offers a powerful approach, whereby biological questions can be addressed in a well-defined framework. By constructing simple gene circuits, such studies have generated new insights into the design principles of gene regulatory networks. Recently, this strategy has been applied to analyze ecological and evolutionary questions, where population-level interactions are critical. Here, we highlight recent development of such systems and discuss how they were used to address problems in ecology and evolutionary biology. As illustrated by these examples, synthetic ecosystems provide a unique platform to study ecological and evolutionary phenomena that are challenging to study in their natural contexts.

Duke Scholars

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Published In

Current opinion in biotechnology

DOI

EISSN

1879-0429

ISSN

0958-1669

Publication Date

October 2012

Volume

23

Issue

5

Start / End Page

791 / 797

Related Subject Headings

  • Synthetic Biology
  • Gene Regulatory Networks
  • Ecosystem
  • Biotechnology
  • Biological Evolution
  • 3206 Medical biotechnology
  • 3106 Industrial biotechnology
  • 3001 Agricultural biotechnology
  • 10 Technology
  • 09 Engineering
 

Citation

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ICMJE
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Tanouchi, Y., Smith, R. P., & You, L. (2012). Engineering microbial systems to explore ecological and evolutionary dynamics. Current Opinion in Biotechnology, 23(5), 791–797. https://doi.org/10.1016/j.copbio.2012.01.006
Tanouchi, Yu, Robert P. Smith, and Lingchong You. “Engineering microbial systems to explore ecological and evolutionary dynamics.Current Opinion in Biotechnology 23, no. 5 (October 2012): 791–97. https://doi.org/10.1016/j.copbio.2012.01.006.
Tanouchi Y, Smith RP, You L. Engineering microbial systems to explore ecological and evolutionary dynamics. Current opinion in biotechnology. 2012 Oct;23(5):791–7.
Tanouchi, Yu, et al. “Engineering microbial systems to explore ecological and evolutionary dynamics.Current Opinion in Biotechnology, vol. 23, no. 5, Oct. 2012, pp. 791–97. Epmc, doi:10.1016/j.copbio.2012.01.006.
Tanouchi Y, Smith RP, You L. Engineering microbial systems to explore ecological and evolutionary dynamics. Current opinion in biotechnology. 2012 Oct;23(5):791–797.
Journal cover image

Published In

Current opinion in biotechnology

DOI

EISSN

1879-0429

ISSN

0958-1669

Publication Date

October 2012

Volume

23

Issue

5

Start / End Page

791 / 797

Related Subject Headings

  • Synthetic Biology
  • Gene Regulatory Networks
  • Ecosystem
  • Biotechnology
  • Biological Evolution
  • 3206 Medical biotechnology
  • 3106 Industrial biotechnology
  • 3001 Agricultural biotechnology
  • 10 Technology
  • 09 Engineering