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Nanomechanics of streptavidin hubs for molecular materials.

Publication ,  Journal Article
Kim, M; Wang, C-C; Benedetti, F; Rabbi, M; Bennett, V; Marszalek, PE
Published in: Adv Mater
December 15, 2011

A new strategy is reported for creating protein-based nanomaterials by genetically fusing large polypeptides to monomeric streptavidin and exploiting the propensity of streptavidin monomers(SM) to self-assemble into stable tetramers. We have characterized the mechanical properties of streptavidin-linked structures and measured, for the first time, the mechanical strength of streptavidin tetramers themselves. Using streptavidin tetramers as molecular hubs offers a unique opportunity to create a variety of well-defined, self-assembled protein-based (nano)materials with unusual mechanical properties.

Duke Scholars

Published In

Adv Mater

DOI

EISSN

1521-4095

Publication Date

December 15, 2011

Volume

23

Issue

47

Start / End Page

5684 / 5688

Location

Germany

Related Subject Headings

  • Temperature
  • Surface Properties
  • Streptavidin
  • Protein Stability
  • Protein Folding
  • Protein Engineering
  • Peptides
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Microscopy, Atomic Force
 

Citation

APA
Chicago
ICMJE
MLA
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Kim, M., Wang, C.-C., Benedetti, F., Rabbi, M., Bennett, V., & Marszalek, P. E. (2011). Nanomechanics of streptavidin hubs for molecular materials. Adv Mater, 23(47), 5684–5688. https://doi.org/10.1002/adma.201103316
Kim, Minkyu, Chien-Chung Wang, Fabrizio Benedetti, Mahir Rabbi, Vann Bennett, and Piotr E. Marszalek. “Nanomechanics of streptavidin hubs for molecular materials.Adv Mater 23, no. 47 (December 15, 2011): 5684–88. https://doi.org/10.1002/adma.201103316.
Kim M, Wang C-C, Benedetti F, Rabbi M, Bennett V, Marszalek PE. Nanomechanics of streptavidin hubs for molecular materials. Adv Mater. 2011 Dec 15;23(47):5684–8.
Kim, Minkyu, et al. “Nanomechanics of streptavidin hubs for molecular materials.Adv Mater, vol. 23, no. 47, Dec. 2011, pp. 5684–88. Pubmed, doi:10.1002/adma.201103316.
Kim M, Wang C-C, Benedetti F, Rabbi M, Bennett V, Marszalek PE. Nanomechanics of streptavidin hubs for molecular materials. Adv Mater. 2011 Dec 15;23(47):5684–5688.
Journal cover image

Published In

Adv Mater

DOI

EISSN

1521-4095

Publication Date

December 15, 2011

Volume

23

Issue

47

Start / End Page

5684 / 5688

Location

Germany

Related Subject Headings

  • Temperature
  • Surface Properties
  • Streptavidin
  • Protein Stability
  • Protein Folding
  • Protein Engineering
  • Peptides
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Microscopy, Atomic Force