Thrombolytic therapy for acute MI in diabetics with retinopathy
Publication
, Journal Article
Mahaffey, KW; Toth, CA; White, HD; Stebbins, AL; Granger, CB; Chatterjee, K
Published in: Cardiology Review
January 1, 1999
Ocular hemorrhage after thrombolytic therapy for acute MI is rare, yet diabetic retinopathy has been considered a contraindication to thrombolysis without clear evidence of an increased risk for ocular hemorrhage. We evaluated 41,021 GUSTO-I trial patients, with and without diabetes, to better define the risk of ocular hemorrhage in acute MI patients treated with thrombolytic therapy. Twelve patients had ocular hemorrhages. Of 6,011 patients with diabetes, only one had an ocular hemorrhage. These data suggest ocular hemorrhage after thrombolytic therapy is extremely uncommon and diabetic retinopathy should not contraindicate thrombolytic therapy in patients with acute MI.
Duke Scholars
Published In
Cardiology Review
ISSN
1092-6607
Publication Date
January 1, 1999
Volume
16
Issue
11
Start / End Page
27 / 32
Related Subject Headings
- Cardiovascular System & Hematology
- 3201 Cardiovascular medicine and haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Mahaffey, K. W., Toth, C. A., White, H. D., Stebbins, A. L., Granger, C. B., & Chatterjee, K. (1999). Thrombolytic therapy for acute MI in diabetics with retinopathy. Cardiology Review, 16(11), 27–32.
Mahaffey, K. W., C. A. Toth, H. D. White, A. L. Stebbins, C. B. Granger, and K. Chatterjee. “Thrombolytic therapy for acute MI in diabetics with retinopathy.” Cardiology Review 16, no. 11 (January 1, 1999): 27–32.
Mahaffey KW, Toth CA, White HD, Stebbins AL, Granger CB, Chatterjee K. Thrombolytic therapy for acute MI in diabetics with retinopathy. Cardiology Review. 1999 Jan 1;16(11):27–32.
Mahaffey, K. W., et al. “Thrombolytic therapy for acute MI in diabetics with retinopathy.” Cardiology Review, vol. 16, no. 11, Jan. 1999, pp. 27–32.
Mahaffey KW, Toth CA, White HD, Stebbins AL, Granger CB, Chatterjee K. Thrombolytic therapy for acute MI in diabetics with retinopathy. Cardiology Review. 1999 Jan 1;16(11):27–32.
Published In
Cardiology Review
ISSN
1092-6607
Publication Date
January 1, 1999
Volume
16
Issue
11
Start / End Page
27 / 32
Related Subject Headings
- Cardiovascular System & Hematology
- 3201 Cardiovascular medicine and haematology