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Extended cardiac tachyarrhythmias in guinea pigs

Publication ,  Journal Article
Malkin, RA; Eynard, JN; Pergola, NF
Published in: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
December 1, 1997

Guinea pigs are frequently used as models for ventricular tachyarrhythmias, including polymorphic ventricular tachycardia and ventricular fibrillation. However, applications of the model for the development of new cardioversion and defibrillation technology are limited because the arrhythmias typically last less than five seconds. This study demonstrates that a brief period of rapid pacing facilitates the initiation of consistent, sustained ventricular tachyarrhythmias in large guinea pigs, eliminating spontaneous termination as a confounding factor in the study of acute therapies.

Duke Scholars

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 1997

Volume

1

Start / End Page

387 / 388
 

Citation

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Malkin, R. A., Eynard, J. N., & Pergola, N. F. (1997). Extended cardiac tachyarrhythmias in guinea pigs. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 1, 387–388.
Malkin, R. A., J. N. Eynard, and N. F. Pergola. “Extended cardiac tachyarrhythmias in guinea pigs.” Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (December 1, 1997): 387–88.
Malkin RA, Eynard JN, Pergola NF. Extended cardiac tachyarrhythmias in guinea pigs. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1997 Dec 1;1:387–8.
Malkin, R. A., et al. “Extended cardiac tachyarrhythmias in guinea pigs.” Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 1, Dec. 1997, pp. 387–88.
Malkin RA, Eynard JN, Pergola NF. Extended cardiac tachyarrhythmias in guinea pigs. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1997 Dec 1;1:387–388.

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 1997

Volume

1

Start / End Page

387 / 388