The kindling model of epilepsy: a critical review.
Publication
, Journal Article
McNamara, JO; Bonhaus, DW; Shin, C; Crain, BJ; Gellman, RL; Giacchino, JL
Published in: CRC Crit Rev Clin Neurobiol
1985
Kindling is an animal model of epilepsy induced by electrical stimulation of the brain. This model has attracted the interest of many neuroscientists, in part because it involves a robust, permanent modification of brain function. This report will describe the kindling phenomenon and critically review current understanding of the underlying mechanisms. The review will carefully consider whether this model accurately reflects analogous processes in humans. The review will consider some hypotheses inspired by the kindling studies which may be relevant to human epilepsy.
Duke Scholars
Published In
CRC Crit Rev Clin Neurobiol
ISSN
0742-941X
Publication Date
1985
Volume
1
Issue
4
Start / End Page
341 / 391
Location
United States
Related Subject Headings
- Narcotics
- Kindling, Neurologic
- Humans
- Epilepsy
- Endorphins
- Electrophysiology
- Electroencephalography
- Biomechanical Phenomena
- Biogenic Amines
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
McNamara, J. O., Bonhaus, D. W., Shin, C., Crain, B. J., Gellman, R. L., & Giacchino, J. L. (1985). The kindling model of epilepsy: a critical review. CRC Crit Rev Clin Neurobiol, 1(4), 341–391.
McNamara, J. O., D. W. Bonhaus, C. Shin, B. J. Crain, R. L. Gellman, and J. L. Giacchino. “The kindling model of epilepsy: a critical review.” CRC Crit Rev Clin Neurobiol 1, no. 4 (1985): 341–91.
McNamara JO, Bonhaus DW, Shin C, Crain BJ, Gellman RL, Giacchino JL. The kindling model of epilepsy: a critical review. CRC Crit Rev Clin Neurobiol. 1985;1(4):341–91.
McNamara, J. O., et al. “The kindling model of epilepsy: a critical review.” CRC Crit Rev Clin Neurobiol, vol. 1, no. 4, 1985, pp. 341–91.
McNamara JO, Bonhaus DW, Shin C, Crain BJ, Gellman RL, Giacchino JL. The kindling model of epilepsy: a critical review. CRC Crit Rev Clin Neurobiol. 1985;1(4):341–391.
Published In
CRC Crit Rev Clin Neurobiol
ISSN
0742-941X
Publication Date
1985
Volume
1
Issue
4
Start / End Page
341 / 391
Location
United States
Related Subject Headings
- Narcotics
- Kindling, Neurologic
- Humans
- Epilepsy
- Endorphins
- Electrophysiology
- Electroencephalography
- Biomechanical Phenomena
- Biogenic Amines
- Animals