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Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom

Publication ,  Journal Article
Faber, TL; Garcia, EV; Lalush, DS; Segars, WP; Tsui, BMW
Published in: Proceedings of SPIE - The International Society for Optical Engineering
January 1, 2001

The spline-based Mathematical Cardiac Torso (MCAT) phantom is a realistic software simulation designed to simulate single photon emission computed tomographic (SPECT) data. It incorporates a heart model of known size and shape; thus, it is invaluable for measuring accuracy of acquisition, reconstruction, and post-processing routines. New functionality has been added by replacing the standard heart model with left ventricular (LV) epicardial and endocardial surface points detected from actual patient SPECT perfusion studies. LV surfaces detected from standard post-processing quantitation programs are converted through interpolation in space and time into new B-spline models. Perfusion abnormalities are added to the model based on results of standard perfusion quantification. The new LV is translated and rotated to fit within existing atria and right ventricular models, which are scaled based on the size of the LV. Simulations were created for five different patients with myocardial infarctions who had undergone SPECT perfusion imaging. Shape, size, and motion of the resulting activity map were compared visually to the original SPECT images. In all cases, size, shape and motion of simulated LVs matched well with the original images. Thus, realistic simulations with known physiologic and functional parameters can be created for evaluating efficacy of processing algorithms.

Duke Scholars

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

ISSN

0277-786X

Publication Date

January 1, 2001

Volume

4319

Start / End Page

22 / 26
 

Citation

APA
Chicago
ICMJE
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Faber, T. L., Garcia, E. V., Lalush, D. S., Segars, W. P., & Tsui, B. M. W. (2001). Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom. Proceedings of SPIE - The International Society for Optical Engineering, 4319, 22–26. https://doi.org/10.1117/12.428050
Faber, T. L., E. V. Garcia, D. S. Lalush, W. P. Segars, and B. M. W. Tsui. “Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom.” Proceedings of SPIE - The International Society for Optical Engineering 4319 (January 1, 2001): 22–26. https://doi.org/10.1117/12.428050.
Faber TL, Garcia EV, Lalush DS, Segars WP, Tsui BMW. Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom. Proceedings of SPIE - The International Society for Optical Engineering. 2001 Jan 1;4319:22–6.
Faber, T. L., et al. “Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 4319, Jan. 2001, pp. 22–26. Scopus, doi:10.1117/12.428050.
Faber TL, Garcia EV, Lalush DS, Segars WP, Tsui BMW. Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom. Proceedings of SPIE - The International Society for Optical Engineering. 2001 Jan 1;4319:22–26.

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

ISSN

0277-786X

Publication Date

January 1, 2001

Volume

4319

Start / End Page

22 / 26