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Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI

Publication ,  Journal Article
Song, AW; Truong, TK
Published in: International Journal of Imaging Systems and Technology
March 1, 2010

In this manuscript, we review the development of an alternative functional magnetic resonance imaging (fMRI) contrast mechanism based on the apparent diffusion coefficient (ADC), in light of the recent progress in other complementary functional imaging contrasts sensitive to cerebral blood flow (CBF) and cerebral blood volume (CBV). Specifically, we discuss the spatial and temporal characteristics of ADC fMRI in localizing neuronal activities, and also draw inference on its potential applicability to achieve fast calibrated fMRI. We found that optimized dynamic ADC contrast can lead to improved spatial localization in small vessel networks close to the true neuronal activities, while having the potential to simultaneously generate the blood oxygenation level-dependent (BOLD) and CBF/CBV contrasts required in a calibrated fMRI experiment. With sufficient signal-to-noise ratio (SNR) and temporal resolution, fMRI based on the dynamic ADC contrast may prove to be an efficient technique to achieve accurate and quantitative measures of neuronal activities. © 2010 Wiley Periodicals, Inc.

Duke Scholars

Published In

International Journal of Imaging Systems and Technology

DOI

EISSN

1098-1098

ISSN

0899-9457

Publication Date

March 1, 2010

Volume

20

Issue

1

Start / End Page

42 / 50

Related Subject Headings

  • Artificial Intelligence & Image Processing
  • 4603 Computer vision and multimedia computation
  • 0801 Artificial Intelligence and Image Processing
 

Citation

APA
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ICMJE
MLA
NLM
Song, A. W., & Truong, T. K. (2010). Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI. International Journal of Imaging Systems and Technology, 20(1), 42–50. https://doi.org/10.1002/ima.20220
Song, A. W., and T. K. Truong. “Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI.” International Journal of Imaging Systems and Technology 20, no. 1 (March 1, 2010): 42–50. https://doi.org/10.1002/ima.20220.
Song AW, Truong TK. Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI. International Journal of Imaging Systems and Technology. 2010 Mar 1;20(1):42–50.
Song, A. W., and T. K. Truong. “Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI.” International Journal of Imaging Systems and Technology, vol. 20, no. 1, Mar. 2010, pp. 42–50. Scopus, doi:10.1002/ima.20220.
Song AW, Truong TK. Apparent diffusion coefficient dependent fMRI: Spatiotemporal characteristics and implications on calibrated fMRI. International Journal of Imaging Systems and Technology. 2010 Mar 1;20(1):42–50.
Journal cover image

Published In

International Journal of Imaging Systems and Technology

DOI

EISSN

1098-1098

ISSN

0899-9457

Publication Date

March 1, 2010

Volume

20

Issue

1

Start / End Page

42 / 50

Related Subject Headings

  • Artificial Intelligence & Image Processing
  • 4603 Computer vision and multimedia computation
  • 0801 Artificial Intelligence and Image Processing