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The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy.

Publication ,  Journal Article
McAdam, LC; Mayo, AL; Alman, BA; Biggar, WD
Published in: Acta Myol
May 2012

Deflazacort is the most commonly prescribed corticosteroid for the treatment of Duchenne muscular dystrophy in Canada. We review the long-term experience with deflazacort treatment at two centers in Canada; Montreal and Toronto. Deflazacort has benefitted both cohorts by prolonged ambulation, preserved cardiac and respiratory function, less scoliosis and improved survival. Common side effects in both cohorts include weight gain, decreased height and cataract formation. The Canadian experience supports the use of deflazacort in treating boys with Duchenne muscular dystrophy.

Duke Scholars

Published In

Acta Myol

ISSN

1128-2460

Publication Date

May 2012

Volume

31

Issue

1

Start / End Page

16 / 20

Location

Italy

Related Subject Headings

  • Weight Gain
  • Walking
  • Spine
  • Spinal Injuries
  • Pregnenediones
  • Neurology & Neurosurgery
  • Muscular Dystrophy, Duchenne
  • Muscle Strength
  • Male
  • Immunosuppressive Agents
 

Citation

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ICMJE
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McAdam, L. C., Mayo, A. L., Alman, B. A., & Biggar, W. D. (2012). The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy. Acta Myol, 31(1), 16–20.
McAdam, Laura C., Amanda L. Mayo, Benjamin A. Alman, and W Douglas Biggar. “The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy.Acta Myol 31, no. 1 (May 2012): 16–20.
McAdam LC, Mayo AL, Alman BA, Biggar WD. The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy. Acta Myol. 2012 May;31(1):16–20.
McAdam, Laura C., et al. “The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy.Acta Myol, vol. 31, no. 1, May 2012, pp. 16–20.
McAdam LC, Mayo AL, Alman BA, Biggar WD. The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy. Acta Myol. 2012 May;31(1):16–20.

Published In

Acta Myol

ISSN

1128-2460

Publication Date

May 2012

Volume

31

Issue

1

Start / End Page

16 / 20

Location

Italy

Related Subject Headings

  • Weight Gain
  • Walking
  • Spine
  • Spinal Injuries
  • Pregnenediones
  • Neurology & Neurosurgery
  • Muscular Dystrophy, Duchenne
  • Muscle Strength
  • Male
  • Immunosuppressive Agents