A classification for genetic disorders of interest to orthopaedists.
Publication
, Journal Article
Alman, BA
Published in: Clin Orthop Relat Res
August 2002
The genetic etiology of many disorders of interest to the orthopaedist now is known. Based on this information, these disorders can be grouped broadly based on the function of the causative gene into five categories: structural, tumor and cell regulatory, developmental, important in nerve or muscle function, and protein processing (enzymes). In addition, some disorders are caused by large chromosomal abnormalities, which comprise a sixth class. Disorders in each of these categories share similarities in their clinical manifestations, treatment, prognosis, and inheritance pattern. This classification is a useful way to remember the major clinical manifestations and treatment principles for genetic disorders of interest to the orthopaedist.
Duke Scholars
Published In
Clin Orthop Relat Res
DOI
ISSN
0009-921X
Publication Date
August 2002
Issue
401
Start / End Page
17 / 26
Location
United States
Related Subject Headings
- Orthopedics
- Orthopedics
- Musculoskeletal Diseases
- Musculoskeletal Abnormalities
- Humans
- Genetic Diseases, Inborn
- Genes, Tumor Suppressor
- Genes, Regulator
- Genes
- Enzymes
Citation
APA
Chicago
ICMJE
MLA
NLM
Alman, B. A. (2002). A classification for genetic disorders of interest to orthopaedists. Clin Orthop Relat Res, (401), 17–26. https://doi.org/10.1097/00003086-200208000-00004
Alman, Benjamin A. “A classification for genetic disorders of interest to orthopaedists.” Clin Orthop Relat Res, no. 401 (August 2002): 17–26. https://doi.org/10.1097/00003086-200208000-00004.
Alman BA. A classification for genetic disorders of interest to orthopaedists. Clin Orthop Relat Res. 2002 Aug;(401):17–26.
Alman, Benjamin A. “A classification for genetic disorders of interest to orthopaedists.” Clin Orthop Relat Res, no. 401, Aug. 2002, pp. 17–26. Pubmed, doi:10.1097/00003086-200208000-00004.
Alman BA. A classification for genetic disorders of interest to orthopaedists. Clin Orthop Relat Res. 2002 Aug;(401):17–26.
Published In
Clin Orthop Relat Res
DOI
ISSN
0009-921X
Publication Date
August 2002
Issue
401
Start / End Page
17 / 26
Location
United States
Related Subject Headings
- Orthopedics
- Orthopedics
- Musculoskeletal Diseases
- Musculoskeletal Abnormalities
- Humans
- Genetic Diseases, Inborn
- Genes, Tumor Suppressor
- Genes, Regulator
- Genes
- Enzymes