Skip to main content
Journal cover image

Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin.

Publication ,  Journal Article
Simpson, MJ; Glass, KE; Wilson, JW; Wilby, PR; Simon, JD; Warren, WS
Published in: The journal of physical chemistry letters
June 2013

Melanins are biological pigments found throughout the animal kingdom that have many diverse functions. Pump-probe imaging can differentiate the two kinds of melanins found in human skin, eumelanin and pheomelanin, the distributions of which are relevant to the diagnosis of melanoma. The long-term stability of the melanin pump-probe signal is central to using this technology to analyze melanin distributions in archived tissue samples to improve diagnostic procedures. This report shows that most of the pump-probe signal from eumelanin derived from a Jurassic cephalopod is essentially identical to that of eumelanin extracted from its modern counterpart, Sepia officinalis. However, additional classes of eumelanin signals found in the fossil reveal that the pump-probe signature is sensitive to iron content, which could be a valuable tool for pathologists who cannot otherwise know the microscopic distributions of iron in melanins.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

The journal of physical chemistry letters

DOI

EISSN

1948-7185

ISSN

1948-7185

Publication Date

June 2013

Volume

4

Issue

11

Start / End Page

1924 / 1927

Related Subject Headings

  • 03 Chemical Sciences
  • 02 Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Simpson, M. J., Glass, K. E., Wilson, J. W., Wilby, P. R., Simon, J. D., & Warren, W. S. (2013). Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin. The Journal of Physical Chemistry Letters, 4(11), 1924–1927. https://doi.org/10.1021/jz4008036
Simpson, Mary Jane, Keely E. Glass, Jesse W. Wilson, Philip R. Wilby, John D. Simon, and Warren S. Warren. “Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin.The Journal of Physical Chemistry Letters 4, no. 11 (June 2013): 1924–27. https://doi.org/10.1021/jz4008036.
Simpson MJ, Glass KE, Wilson JW, Wilby PR, Simon JD, Warren WS. Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin. The journal of physical chemistry letters. 2013 Jun;4(11):1924–7.
Simpson, Mary Jane, et al. “Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin.The Journal of Physical Chemistry Letters, vol. 4, no. 11, June 2013, pp. 1924–27. Epmc, doi:10.1021/jz4008036.
Simpson MJ, Glass KE, Wilson JW, Wilby PR, Simon JD, Warren WS. Pump-Probe Microscopic Imaging of Jurassic-Aged Eumelanin. The journal of physical chemistry letters. 2013 Jun;4(11):1924–1927.
Journal cover image

Published In

The journal of physical chemistry letters

DOI

EISSN

1948-7185

ISSN

1948-7185

Publication Date

June 2013

Volume

4

Issue

11

Start / End Page

1924 / 1927

Related Subject Headings

  • 03 Chemical Sciences
  • 02 Physical Sciences