Determining γδ versus αß T cell development.
Publication
, Journal Article
Ciofani, M; Zúñiga-Pflücker, JC
Published in: Nat Rev Immunol
September 2010
The thymus produces several types of functionally distinct T cell subsets. However, at a more fundamental level only two genetically distinct T cell lineages exist: the γδ and αß T cell lineages. Precisely how these two T cell lineages are generated from common thymocyte progenitor cells remains to be fully elucidated and is under intense investigation. Here, we highlight recent findings that have helped to provide important clues to the mechanisms that underpin the generation of γδ T cells in the mouse thymus.
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Published In
Nat Rev Immunol
DOI
EISSN
1474-1741
Publication Date
September 2010
Volume
10
Issue
9
Start / End Page
657 / 663
Location
England
Related Subject Headings
- T-Lymphocyte Subsets
- Receptors, Antigen, T-Cell, gamma-delta
- Receptors, Antigen, T-Cell, alpha-beta
- Mice
- Immunology
- Cell Lineage
- Cell Differentiation
- Animals
- 3204 Immunology
- 1107 Immunology
Citation
APA
Chicago
ICMJE
MLA
NLM
Ciofani, M., & Zúñiga-Pflücker, J. C. (2010). Determining γδ versus αß T cell development. Nat Rev Immunol, 10(9), 657–663. https://doi.org/10.1038/nri2820
Ciofani, Maria, and Juan Carlos Zúñiga-Pflücker. “Determining γδ versus αß T cell development.” Nat Rev Immunol 10, no. 9 (September 2010): 657–63. https://doi.org/10.1038/nri2820.
Ciofani M, Zúñiga-Pflücker JC. Determining γδ versus αß T cell development. Nat Rev Immunol. 2010 Sep;10(9):657–63.
Ciofani, Maria, and Juan Carlos Zúñiga-Pflücker. “Determining γδ versus αß T cell development.” Nat Rev Immunol, vol. 10, no. 9, Sept. 2010, pp. 657–63. Pubmed, doi:10.1038/nri2820.
Ciofani M, Zúñiga-Pflücker JC. Determining γδ versus αß T cell development. Nat Rev Immunol. 2010 Sep;10(9):657–663.
Published In
Nat Rev Immunol
DOI
EISSN
1474-1741
Publication Date
September 2010
Volume
10
Issue
9
Start / End Page
657 / 663
Location
England
Related Subject Headings
- T-Lymphocyte Subsets
- Receptors, Antigen, T-Cell, gamma-delta
- Receptors, Antigen, T-Cell, alpha-beta
- Mice
- Immunology
- Cell Lineage
- Cell Differentiation
- Animals
- 3204 Immunology
- 1107 Immunology