Recent Publications
Emerging roles of ubiquitin-specific proteases in the cardiovascular system.
Journal Article Mol Pharmacol · January 2026 The universal posttranslational modification ubiquitination was originally discovered in the 1980s as a tag appended to cellular proteins to mark them for degradation by the 26S proteasomal complex. Subsequent discoveries have established ubiquitination as ... Full text Link to item CiteALDH2 and NFκB Activation Restores VEGFR2 Expression and Angiogenesis Impaired by 4-HNE in Coronary Endothelial Cells.
Journal Article Cell biochemistry and function · January 2026 4-hydroxy-2-nonenal (4HNE), a reactive aldehyde produced during lipid peroxidation, reduces angiogenesis in cultured mouse coronary endothelial cells (MCECs). In our previous studies, we found that 4HNE lowers both mRNA and protein levels of vascular endot ... Full text CiteTargeted Overexpression of Mitochondrial ALDH2 in Coronary Endothelial Cells Mitigates HFpEF in a Diabetic Mouse Model.
Journal Article Biomolecules · July 2025 Heart failure (HF) has become an epidemic, with a prevalence of ~7 million cases in the USA. Despite accounting for nearly 50% of all HF cases, heart failure with a preserved ejection fraction (HFpEF) remains challenging to treat. Common pathophysiological ... Full text CiteRecent Grants
Engineering a New Class of Therapies for Heart Failure
ResearchPostdoctoral Associate · Awarded by American Heart Association · 2025 - 2030Targeting the PAR1/IL-17 signaling axis in Chronic Thromboembolic Pulmonary Hypertension
ResearchPostdoctoral Associate · Awarded by University of Colorado Anschutz Medical Campus · 2025 - 2029Regulation of myocardial GPCRs by USP20 in normal and hypertrophied heart
ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2021 - 2025View All Grants