Recent Publications
Decoding Tumor Angiogenesis for Therapeutic Advancements: Mechanistic Insights.
Journal Article Biomedicines · April 2024 Tumor angiogenesis, the formation of new blood vessels within the tumor microenvironment, is considered a hallmark of cancer progression and represents a crucial target for therapeutic intervention. The tumor microenvironment is characterized by a complex ... Full text CiteSARS-CoV-2 infection and diabetes: Pathophysiological mechanism of multi-system organ failure.
Journal Article World journal of virology · September 2022 Since the discovery of the coronavirus disease 2019 outbreak, a vast majority of studies have been carried out that confirmed the worst outcome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in people with preexisting health cond ... Full text CiteAldehyde Dehydrogenase 2 Activator Augments the Beneficial Effects of Empagliflozin in Mice with Diabetes-Associated HFpEF.
Journal Article International journal of molecular sciences · September 2022 To ameliorate diabetes mellitus-associated heart failure with preserved ejection fraction (HFpEF), we plan to lower diabetes-mediated oxidative stress-induced 4-hydroxy-2-nonenal (4HNE) accumulation by pharmacological agents that either decrease 4HNE gener ... Full text CiteRecent Grants
Engineering a New Class of Therapies for Heart Failure
ResearchPostdoctoral Associate · Awarded by American Heart Association · 2025 - 2030Regulation of myocardial GPCRs by USP20 in normal and hypertrophied heart
ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2021 - 2025View All Grants