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Cordelia Manickam

Assistant Professor in Surgery
Surgery, Surgical Sciences

Current Appointments & Affiliations


Assistant Professor in Surgery · 2022 - Present Surgery, Surgical Sciences, Surgery

Recent Publications


Knockdowns of CD3zeta Chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity Against Human Immunodeficiency Virus-1.

Journal Article AIDS Res Hum Retroviruses · November 2024 Multifaceted natural killer (NK) cell activities are indispensable for controlling human immunodeficiency virus (HIV)-1 transmission and pathogenesis. Among the diverse functions of NK cells, antibody-dependent cellular cytotoxicity (ADCC) has been shown t ... Full text Link to item Cite

FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and regulates IgA-class specific signaling and functions.

Journal Article Mucosal Immunol · August 2024 Immunoglobulin A (IgA) is the predominant mucosal antibody class with both anti- and pro-inflammatory roles1-3. However, the specific role of the IgA receptor cluster of differentiation (CD)89, expressed by a subset of natural killer (NK) cells, is poorly ... Full text Link to item Cite

NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage.

Journal Article PLoS Pathog · August 2024 Natural killer (NK) cells play a critical role in virus control. However, it has remained largely unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic. To address this deficit, we employed a validated experimental NK ce ... Full text Link to item Cite
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Recent Grants


Role of eosinophils in SIV infection

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2025

Natural killer cell receptor-expressing B cells as regulators of mucosal immunity in SIV infection

ResearchProgram Manager · Awarded by National Institutes of Health · 2021 - 2022

Microbial and innate immune mechanisms of oral inflammation during SIV infection

ResearchInvestigator · Awarded by National Institutes of Health · 2021 - 2022

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Education, Training & Certifications


The Ohio State University, College of Medicine · 2013 Ph.D.
University of Madras (India) · 2006 D.V.M.