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Daniel Buckland

Assistant Professor of Emergency Medicine
Emergency Medicine
DUMC Box 3096, 2301 Erwin Road, Durham, NC 27710
2301 Erwin Road, DUMC Box 3096, Durham, NC 27710

Selected Publications


Expiration analysis of the International Space Station formulary for exploration mission planning.

Journal Article NPJ Microgravity · July 23, 2024 Effective medications will be required to maintain human health for long-duration space operations. Previous studies have explored the stability and potency of several of the medications used on the International Space Station (ISS). This study is a compre ... Full text Link to item Cite

Incorporation of Drone Technology Into the Chain of Survival for OHCA: Estimation of Time Needed for Bystander Treatment of OHCA and CPR Performance.

Journal Article Circ Cardiovasc Qual Outcomes · April 2024 BACKGROUND: Drone-delivered automated external defibrillators (AEDs) hold promises in the treatment of out-of-hospital cardiac arrest. Our objective was to estimate the time needed to perform resuscitation with a drone-delivered AED and to measure cardiopu ... Full text Link to item Cite

Levels of evidence for human system risk evaluation.

Journal Article NPJ Microgravity · March 20, 2024 NASA uses a continuous risk management process to seek out new knowledge of spaceflight-induced risk to human health and performance. The evidence base that informs the risk assessments in this domain is constantly changing as more information is gleaned f ... Full text Link to item Cite

Causal diagramming for assessing human system risk in spaceflight.

Journal Article NPJ Microgravity · March 19, 2024 For over a decade, the National Aeronautics and Space Administration (NASA) has tracked and configuration-managed approximately 30 risks that affect astronaut health and performance before, during and after spaceflight. The Human System Risk Board (HSRB) a ... Full text Link to item Cite

Development, Deployment, and Implementation of a Machine Learning Surgical Case Length Prediction Model and Prospective Evaluation.

Journal Article Ann Surg · December 1, 2023 OBJECTIVE: To implement a machine learning model using only the restricted data available at case creation time to predict surgical case length for multiple services at different locations. BACKGROUND: The operating room is one of the most expensive resour ... Full text Open Access Link to item Cite

Adequacy of in-mission training to treat tibial shaft fractures in mars analogue testing.

Journal Article Sci Rep · October 23, 2023 Long bone fractures are a concern in long-duration exploration missions (LDEM) where crew autonomy will exceed the current Low Earth Orbit paradigm. Current crew selection assumptions require extensive complete training and competency testing prior to flig ... Full text Open Access Link to item Cite

FedScore: A privacy-preserving framework for federated scoring system development.

Journal Article J Biomed Inform · October 2023 OBJECTIVE: We propose FedScore, a privacy-preserving federated learning framework for scoring system generation across multiple sites to facilitate cross-institutional collaborations. MATERIALS AND METHODS: The FedScore framework includes five modules: fed ... Full text Link to item Cite

Updates to the NASA human system risk management process for space exploration.

Journal Article NPJ Microgravity · September 7, 2023 This paper describes updates to NASA's approach for assessing and mitigating spaceflight-induced risks to human health and performance. This approach continues to evolve to meet dynamically changing risk environments: lunar missions are currently being des ... Full text Link to item Cite

Optimizing a Drone Network to Respond to Opioid Overdoses.

Journal Article West J Emerg Med · September 2023 Introduction:Effective out-of-hospital administration of naloxone in opioid overdoses is dependent on timely arrival of naloxone. Delays in emergency medical services (EMS) response time could potentially be overcome with drones to deliver naloxone efficie ... Full text Link to item Cite

Development and Testing of a Durable and Novel Breast Phantom for Robotic Autonomous Ultrasound Systems

Journal Article Journal of Medical Robotics Research · December 1, 2022 For the safe and effective development of evolving autonomous medical robotic systems that traverse the surface of the body, like in breast ultrasound scans, developing phantoms that are durable and mechanically mimic human tissue is critical. In this work ... Full text Open Access Cite

Estimation of Surgery Durations Using Machine Learning Methods-A Cross-Country Multi-Site Collaborative Study.

Journal Article Healthcare (Basel) · June 25, 2022 The scheduling of operating room (OR) slots requires the accurate prediction of surgery duration. We evaluated the performance of existing Moving Average (MA) based estimates with novel machine learning (ML)-based models of surgery durations across two sit ... Full text Link to item Cite

Estimating medical risk in human spaceflight.

Journal Article NPJ Microgravity · March 31, 2022 NASA and commercial spaceflight companies will soon be retuning humans to the Moon and then eventually sending them on to Mars. These distant planetary destinations will pose new risks-in particular for the health of the astronaut crews. The bulk of the ev ... Full text Open Access Link to item Cite

NASA’s Identified Risks of Adverse Outcomes Due to Inadequate Human Systems Integration Architecture in Human Spaceflight

Conference AHFE International · 2022 The NASA Human System Risk Board (HSRB) has the overall responsibility for tracking the evolution of the top ~30 human system risks that it has identified to be associated with human spaceflight.  As part of this process, the Board is charged with  ... Full text Cite

Durable Breast Phantom with Geometric and Mechanical Properties approximating Human Tissue for Ultrasound Image and Robotic System Testing

Conference 2022 International Symposium on Medical Robotics, ISMR 2022 · January 1, 2022 As robotic movement starts to play a larger role in medical procedures, like breast ultrasound collection, there is an increasing need for mechanically accurate and durable breast phantoms that still have effective imaging properties. In this paper we pres ... Full text Cite

Development and Validation of Machine Learning Models to Predict Admission From Emergency Department to Inpatient and Intensive Care Units.

Journal Article Ann Emerg Med · August 2021 STUDY OBJECTIVE: This study aimed to develop and validate 2 machine learning models that use historical and current-visit patient data from electronic health records to predict the probability of patient admission to either an inpatient unit or ICU at each ... Full text Link to item Cite

Effect of language interpretation modality on throughput and mortality for critical care patients: A retrospective observational study.

Journal Article J Am Coll Emerg Physicians Open · August 2021 OBJECTIVE: Limited data exist describing possible delays in patient transfer from the emergency department (ED) as a result of language barriers and the effects of interpretation services. We described the differences in ED length of stay (LOS) before inte ... Full text Open Access Link to item Cite

CPT to RVU conversion improves model performance in the prediction of surgical case length.

Journal Article Sci Rep · July 8, 2021 Methods used to predict surgical case time often rely upon the current procedural terminology (CPT) code as a nominal variable to train machine-learned models, however this limits the ability of the model to incorporate new procedures and adds complexity a ... Full text Open Access Link to item Cite

Touch-Point Detection Using Thermal Video With Applications to Prevent Indirect Virus Spread.

Journal Article IEEE J Transl Eng Health Med · 2021 Viral and bacterial pathogens can be transmitted through direct contact with contaminated surfaces. Efficient decontamination of contaminated surfaces could lead to decreased disease transmission, if optimized methods for detecting contaminated surfaces ca ... Full text Link to item Cite

Creation of an Automated Fluorescence Guided Tumor Ablation System.

Journal Article IEEE J Transl Eng Health Med · 2021 OBJECTIVE: Create a device that improves the identification and extent of resection at the interface between healthy and tumor tissue; ultimately, using this device would improve surgical outcomes for patients and increase survival. METHODS: We have create ... Full text Link to item Cite

Expiration analysis of the International Space Station formulary for exploration mission planning.

Journal Article NPJ Microgravity · July 23, 2024 Effective medications will be required to maintain human health for long-duration space operations. Previous studies have explored the stability and potency of several of the medications used on the International Space Station (ISS). This study is a compre ... Full text Link to item Cite

Incorporation of Drone Technology Into the Chain of Survival for OHCA: Estimation of Time Needed for Bystander Treatment of OHCA and CPR Performance.

Journal Article Circ Cardiovasc Qual Outcomes · April 2024 BACKGROUND: Drone-delivered automated external defibrillators (AEDs) hold promises in the treatment of out-of-hospital cardiac arrest. Our objective was to estimate the time needed to perform resuscitation with a drone-delivered AED and to measure cardiopu ... Full text Link to item Cite

Levels of evidence for human system risk evaluation.

Journal Article NPJ Microgravity · March 20, 2024 NASA uses a continuous risk management process to seek out new knowledge of spaceflight-induced risk to human health and performance. The evidence base that informs the risk assessments in this domain is constantly changing as more information is gleaned f ... Full text Link to item Cite

Causal diagramming for assessing human system risk in spaceflight.

Journal Article NPJ Microgravity · March 19, 2024 For over a decade, the National Aeronautics and Space Administration (NASA) has tracked and configuration-managed approximately 30 risks that affect astronaut health and performance before, during and after spaceflight. The Human System Risk Board (HSRB) a ... Full text Link to item Cite

Development, Deployment, and Implementation of a Machine Learning Surgical Case Length Prediction Model and Prospective Evaluation.

Journal Article Ann Surg · December 1, 2023 OBJECTIVE: To implement a machine learning model using only the restricted data available at case creation time to predict surgical case length for multiple services at different locations. BACKGROUND: The operating room is one of the most expensive resour ... Full text Open Access Link to item Cite

Adequacy of in-mission training to treat tibial shaft fractures in mars analogue testing.

Journal Article Sci Rep · October 23, 2023 Long bone fractures are a concern in long-duration exploration missions (LDEM) where crew autonomy will exceed the current Low Earth Orbit paradigm. Current crew selection assumptions require extensive complete training and competency testing prior to flig ... Full text Open Access Link to item Cite

FedScore: A privacy-preserving framework for federated scoring system development.

Journal Article J Biomed Inform · October 2023 OBJECTIVE: We propose FedScore, a privacy-preserving federated learning framework for scoring system generation across multiple sites to facilitate cross-institutional collaborations. MATERIALS AND METHODS: The FedScore framework includes five modules: fed ... Full text Link to item Cite

Updates to the NASA human system risk management process for space exploration.

Journal Article NPJ Microgravity · September 7, 2023 This paper describes updates to NASA's approach for assessing and mitigating spaceflight-induced risks to human health and performance. This approach continues to evolve to meet dynamically changing risk environments: lunar missions are currently being des ... Full text Link to item Cite

Optimizing a Drone Network to Respond to Opioid Overdoses.

Journal Article West J Emerg Med · September 2023 Introduction:Effective out-of-hospital administration of naloxone in opioid overdoses is dependent on timely arrival of naloxone. Delays in emergency medical services (EMS) response time could potentially be overcome with drones to deliver naloxone efficie ... Full text Link to item Cite

Development and Testing of a Durable and Novel Breast Phantom for Robotic Autonomous Ultrasound Systems

Journal Article Journal of Medical Robotics Research · December 1, 2022 For the safe and effective development of evolving autonomous medical robotic systems that traverse the surface of the body, like in breast ultrasound scans, developing phantoms that are durable and mechanically mimic human tissue is critical. In this work ... Full text Open Access Cite

Estimation of Surgery Durations Using Machine Learning Methods-A Cross-Country Multi-Site Collaborative Study.

Journal Article Healthcare (Basel) · June 25, 2022 The scheduling of operating room (OR) slots requires the accurate prediction of surgery duration. We evaluated the performance of existing Moving Average (MA) based estimates with novel machine learning (ML)-based models of surgery durations across two sit ... Full text Link to item Cite

Estimating medical risk in human spaceflight.

Journal Article NPJ Microgravity · March 31, 2022 NASA and commercial spaceflight companies will soon be retuning humans to the Moon and then eventually sending them on to Mars. These distant planetary destinations will pose new risks-in particular for the health of the astronaut crews. The bulk of the ev ... Full text Open Access Link to item Cite

NASA’s Identified Risks of Adverse Outcomes Due to Inadequate Human Systems Integration Architecture in Human Spaceflight

Conference AHFE International · 2022 The NASA Human System Risk Board (HSRB) has the overall responsibility for tracking the evolution of the top ~30 human system risks that it has identified to be associated with human spaceflight.  As part of this process, the Board is charged with  ... Full text Cite

Durable Breast Phantom with Geometric and Mechanical Properties approximating Human Tissue for Ultrasound Image and Robotic System Testing

Conference 2022 International Symposium on Medical Robotics, ISMR 2022 · January 1, 2022 As robotic movement starts to play a larger role in medical procedures, like breast ultrasound collection, there is an increasing need for mechanically accurate and durable breast phantoms that still have effective imaging properties. In this paper we pres ... Full text Cite

Development and Validation of Machine Learning Models to Predict Admission From Emergency Department to Inpatient and Intensive Care Units.

Journal Article Ann Emerg Med · August 2021 STUDY OBJECTIVE: This study aimed to develop and validate 2 machine learning models that use historical and current-visit patient data from electronic health records to predict the probability of patient admission to either an inpatient unit or ICU at each ... Full text Link to item Cite

Effect of language interpretation modality on throughput and mortality for critical care patients: A retrospective observational study.

Journal Article J Am Coll Emerg Physicians Open · August 2021 OBJECTIVE: Limited data exist describing possible delays in patient transfer from the emergency department (ED) as a result of language barriers and the effects of interpretation services. We described the differences in ED length of stay (LOS) before inte ... Full text Open Access Link to item Cite

CPT to RVU conversion improves model performance in the prediction of surgical case length.

Journal Article Sci Rep · July 8, 2021 Methods used to predict surgical case time often rely upon the current procedural terminology (CPT) code as a nominal variable to train machine-learned models, however this limits the ability of the model to incorporate new procedures and adds complexity a ... Full text Open Access Link to item Cite

Touch-Point Detection Using Thermal Video With Applications to Prevent Indirect Virus Spread.

Journal Article IEEE J Transl Eng Health Med · 2021 Viral and bacterial pathogens can be transmitted through direct contact with contaminated surfaces. Efficient decontamination of contaminated surfaces could lead to decreased disease transmission, if optimized methods for detecting contaminated surfaces ca ... Full text Link to item Cite

Creation of an Automated Fluorescence Guided Tumor Ablation System.

Journal Article IEEE J Transl Eng Health Med · 2021 OBJECTIVE: Create a device that improves the identification and extent of resection at the interface between healthy and tumor tissue; ultimately, using this device would improve surgical outcomes for patients and increase survival. METHODS: We have create ... Full text Link to item Cite

A Novel Robotic System for Ultrasound-guided Peripheral Vascular Localization

Conference Proceedings - IEEE International Conference on Robotics and Automation · January 1, 2021 In this paper, we present an autonomous RGBD and 2D ultrasound-guided robotic system for collecting 3D localized volumes of peripheral vessels. This compact design, with available commercial components, lends itself to platform utility throughout the human ... Full text Cite

Abstract 231: Single Bystander CPR Performance During Drone AED Delivery for Simulated Out of Hospital Cardiac Arrest

Conference Circulation · November 17, 2020 Background: Drones have great potential to speed the delivery of AEDs in the critical first few minutes of OHCA. However, it is unclear whether bystanders can balance high-quality cardiopulmonary resu ... Full text Cite

BYSTANDER PERFORMANCE DURING SIMULATED DRONE DELIVERY OF AN AED FOR MOCK OUT-OF-HOSPITAL CARDIAC ARREST

Journal Article Journal of the American College of Cardiology · March 2020 Full text Cite

162 Optimizing a Drone Network to Deliver Naloxone

Conference Annals of Emergency Medicine · October 2019 Full text Cite

Engineering, Life Sciences, and Health/Medicine Synergy in Aerospace Human Systems Integration: The Rosetta Stone Project - An Executive Summary

Journal Article New Space · June 1, 2019 The successful design, development, and operation of human-rated and human-operated systems require the combined effort of engineering, science, and human health disciplines. This is extremely important to minimize risk and ensure safe operation of complex ... Full text Cite

Design Considerations for UAV-Delivered Opioid Overdose Interventions

Conference IEEE Aerospace Conference Proceedings · March 1, 2019 With recent regulatory changes that allow for commercial unmanned aerial vehicle (UAV)operations, there has been increasing interest in using UAVs, aka drones, for delivery of medical care, especially in rural areas. Previous work has focused on Automated ... Full text Cite

Ketamine in the Prehospital Environment: A National Survey of Paramedics in the United States.

Journal Article Prehosp Disaster Med · February 2018 BACKGROUND: Use of ketamine in the prehospital setting may be advantageous due to its potent analgesic and sedative properties and favorable risk profile. Use in the military setting has demonstrated both efficacy and safety for pain relief. The purpose of ... Full text Link to item Cite

Crew Recovery and Contingency Planning for a Manned Stratospheric Balloon Flight - the StratEx Program.

Journal Article Prehosp Disaster Med · October 2016 The StratEx program used a self-contained space suit and balloon system to loft pilot Alan Eustace to a record-breaking altitude and skydive from 135,897 feet (41,422 m). After releasing from the balloon and a stabilized freefall, the pilot safely landed u ... Full text Link to item Cite

Emergency Medical Considerations in a Space-Suited Patient.

Journal Article Aerosp Med Hum Perform · 2016 The Stratex Project is a high altitude balloon flight that culminated in a freefall from 41,422 m (135,890 ft), breaking the record for the highest freefall to date. Crew recovery operations required an innovative approach due to the unique nature of the e ... Full text Link to item Cite

Long-term biomechanical outcomes after Achilles tendon ruptures.

Journal Article Knee Surg Sports Traumatol Arthrosc · March 2015 PURPOSE: The ideal treatment for Achilles tendon ruptures is still unknown. Biomechanical were correlated to radiological and clinical parameters to study outcomes. METHODS: In this retrospective, assessor-blinded multi-centre cohort study, 52 patients wit ... Full text Link to item Cite

Meta-analysis on biomechanical properties of meniscus repairs: are devices better than sutures?

Journal Article Knee Surg Sports Traumatol Arthrosc · January 2015 PURPOSE: Meniscal repair devices have been extensively tested during the past decades as reported in the literature. Reviewing the different meniscal repair devices and sutures with their respective biomechanical properties. METHODS: For this meta-analysis ... Full text Link to item Cite

In vivo glenohumeral translation under anterior loading in an open-MRI set-up.

Journal Article J Biomech · November 28, 2014 The evaluation of the glenohumeral joint laxity requires the estimate of displacements of the humeral head centre (HHC) with respect to the glenoid. To the authors׳ knowledge, several studies have been conducted to estimate HHC translations in vivo but dat ... Full text Link to item Cite

Dynamic ultrasound imaging of cervical spine intervertebral discs

Conference IEEE International Ultrasonics Symposium, IUS · October 20, 2014 The health of the cervical spine is commonly evaluated by static X-Ray, CT or MRI images; however, they are unable to reveal its dynamic performance and functionality. Ultrasound is introduced as a non-invasive, real-time quantitative tool to assess the dy ... Full text Cite

All-inside meniscal repair devices compared with their matched inside-out vertical mattress suture repair: introducing 10,000 and 100,000 loading cycles.

Journal Article Am J Sports Med · September 2014 BACKGROUND: All-inside arthroscopic meniscal repairs are favored by most clinicians because of their lower complication rate and decreased morbidity compared with inside-out techniques. Until now, only 1000 cycles have been used for biomechanical testing. ... Full text Link to item Cite

Dynamic ultrasound imaging of cervical spine intervertebral discs

Conference IEEE International Ultrasonics Symposium, IUS · December 1, 2013 Ultrasound can provide a non-invasive quantitative tool to image acute and chronic cervical spine injury and disease. Our work demonstrates that ultrasound is able to quantify intervertebral disc(IVD) deformation of cervical spine functional spine units' a ... Full text Cite

Long-term outcomes of muscle volume and Achilles tendon length after Achilles tendon ruptures.

Journal Article Knee Surg Sports Traumatol Arthrosc · June 2013 PURPOSE: The best treatment for Achilles tendon (AT) ruptures remains controversial. Long-term follow-up with radiological and clinical measurements is needed. METHODS: In this retrospective multicentre cohort study, patients (n = 52) were assessed at a me ... Full text Link to item Cite

The use of an extended ventilation tube as a countermeasure for EVA-associated upper extremity medical issues

Journal Article Acta Astronautica · October 1, 2008 Introduction: Onycholysis due to repetitive activity in the space suit glove during Neutral Buoyancy Laboratory (NBL) training and during spaceflight extravehicular activity (EVA) is a common observation. Moisture accumulates in gloves during EVA task perf ... Full text Cite

Desktop-VR system for preflight 3D navigation training

Journal Article Acta Astronautica · October 1, 2008 Crews who inhabit spacecraft with complex 3D architecture frequently report inflight disorientation and navigation problems. Preflight virtual reality (VR) training may reduce those risks. Although immersive VR techniques may better support spatial orienta ... Full text Cite

Pharmaceutical Stability After Exposure To Vacuum

Conference To prepare for increasingly longer duration space missions during which evacuation to earth is not an option, greater emphasis is being placed on non-invasive and pharmaceutical management of medical emergencies. Early investigations have highlighted the ... Link to item Cite