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Daniel Gonzalez

Associate Professor in Medicine
Medicine, Clinical Pharmacology
P.O. Box 17969, Duke Clinical Reserach Institute, Durham, NC 27715
300 W. Morgan Street, Durham, NC 27701

Overview


Dr. Daniel Gonzalez is an Associate Professor in the Division of Clinical Pharmacology of the Department of Medicine at the Duke University School of Medicine, and a member of the Duke Clinical Research Institute. He also has a secondary appointment in the Department of Pharmacology and Cancer Biology. Dr. Gonzalez received his PharmD and PhD from the University of Florida College of Pharmacy in 2008 and 2012, respectively. He then completed a postdoctoral fellowship through the UNC-Duke Collaborative Clinical Pharmacology T32 Postdoctoral Training Program. Following completion of his post-doctoral training, Dr. Gonzalez served as a faculty member at the UNC Eshelman School of Pharmacy between 2014 and 2023 and moved to Duke University in 2023. 

Dr. Gonzalez’s experiences have afforded a highly collaborative and multidisciplinary research program focused on advancing public health by promoting the safe, effective, and individualized use of drugs, with an emphasis on pediatric populations. His research interests include clinical pharmacology and applying mathematical modeling and simulation techniques to characterize the pharmacokinetics and pharmacodynamics of drugs, guide drug dosage selection, and improve drug safety. Dr. Gonzalez’s research program is funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and he has published >115 peer-reviewed publications and >40 abstracts. He has been the major advisor for 8 PhD students (5 completed, 3 in training) and 15 postdoctoral fellows.

Current Appointments & Affiliations


Associate Professor in Medicine · 2024 - Present Medicine, Clinical Pharmacology, Medicine
Associate Professor in Pharmacology and Cancer Biology · 2024 - Present Pharmacology & Cancer Biology, Basic Science Departments
Member in the Duke Clinical Research Institute · 2023 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children.

Journal Article J Clin Pharmacol · January 2026 Methadone is used in hospitalized children to treat pain and iatrogenic opiate withdrawal. Optimal pediatric dosing for both enteral and intravenous methadone is unknown. We conducted two prospective, multi-center, open-label studies to characterize the ph ... Full text Link to item Cite
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Recent Grants


Best Pharmaceuticals for Children Act Pediatric Trials Network

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2032

PTN 3.0 Task Order #2_ BPCA Pediatric Drug Development Clinical Trial Infrastructure

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030

iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030

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Education, Training & Certifications


University of Florida · 2012 Ph.D.
University of Florida · 2008 Pharm.D.