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Darin Lyn Dufault

Associate Professor of Medicine
Medicine, Gastroenterology

Overview


My work is focused on the management of complex lesions of the GI tract, including advanced adenomas, dysplasia, and early cancers.  This is done through the use of advanced luminal endoscopic techniques such as endoscopic submucosal dissection, mucosal resection, full thickness resection, and endoscopic suturing.  Additionally, I treat motility disorders of the esophagus and stomach through the use of per oral endoscopic myotomy, as well as gastroesophageal reflux with transoral incisionless fundoplication. 

My research interest focuses mainly in the development of novel devices and technology to make endoscopic procedures safer and more effective for patients.  



keywords: submucosal dissection, mucosal resection, per oral endoscopic myotomy, ESD, EMR, POEM, endoscopic suturing, achalasia, jackhammer esophagus, pyloromyotomy, colon polyp, gastric polyp, dysplasia, esophageal cancer, gastric cancer, colon cancer, rectal cancer, Barrett's esophagus

Current Appointments & Affiliations


Associate Professor of Medicine · 2024 - Present Medicine, Gastroenterology, Medicine
Director of Third Space Endoscopy · 2019 - Present Medicine, Gastroenterology, Medicine

Recent Publications


Deep learning classification of ex vivo human colon tissues using spectroscopic optical coherence tomography.

Journal Article J Biophotonics · September 2024 Screening for colorectal cancer (CRC) with colonoscopy has improved patient outcomes; however, it remains the third leading cause of cancer-related mortality, novel strategies to improve screening are needed. Here, we propose an optical biopsy technique ba ... Full text Link to item Cite
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Recent Grants


TRX-2021-05 North Carolina Blue Cross Blue Shield Esophageal Therapeutics (NC BEST) Registry

Clinical TrialPrincipal Investigator · Awarded by Ethicon Endo-Surgery, Inc. · 2022 - 2025

Evaluation of Duodenoscope Contamination Following Implementation of Disposable Heads at Duke Hospital and Duke GI Endoscopy Clinics

ResearchPrincipal Investigator · Awarded by North Carolina Society for Gastroenterology · 2021 - 2023

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Education


Wake Forest University, School of Medicine · 2010 M.D.