Scholars@Duke
Eric McAdams Wilson

Eric McAdams Wilson

Clinical Associate in the Department of Surgery
Community General Surgery
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Selected Publications

Duality of innate stress responses in cardiac injury, repair, and remodeling.

Journal Article J Mol Cell Cardiol · October 2004 The ability of the myocardium to successfully adapt to cardiac injury ultimately determines whether the heart will decompensate and fail, or whether instead it will maintain preserved function. Despite the importance of the myocardial response to cardiac i ... Full text Link to item Cite

Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes.

Journal Article Circulation · January 20, 2004 BACKGROUND: Recent studies suggest that posttranslation processing or "shedding" (ie, secretion) of tumor necrosis factor (TNF) by tumor necrosis factor-alpha converting enzyme (TACE) may contribute to the left ventricular (LV) remodeling that occurs in th ... Full text Link to item Cite

Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling.

Journal Article Circulation · June 10, 2003 BACKGROUND: Induction of matrix metalloproteinases (MMPs) contributes to adverse remodeling after myocardial infarction (MI). Whether a region- and type-specific distribution of MMPs occurs within the post-MI myocardium remained unknown. METHODS AND RESULT ... Full text Link to item Cite

Plasma matrix metalloproteinase and inhibitor profiles in patients with heart failure.

Journal Article J Card Fail · December 2002 BACKGROUND: Changes in myocardial matrix metalloproteinases (MMPs) and the inhibitors of MMPs (TIMPs) have been demonstrated in congestive heart failure (CHF). The first objective of this study was to measure plasma profiles of MMPs and TIMPs in CHF patien ... Full text Link to item Cite

Myocardial remodelling and matrix metalloproteinases in heart failure: turmoil within the interstitium.

Journal Article Ann Med · December 2001 The progression of left ventricular (LV) dysfunction is often accompanied by changes in LV geometry and myocardial architecture that can be defined as LV myocardial remodelling. An important event in LV myocardial remodelling is alterations in the extracel ... Full text Link to item Cite