Scholars@Duke
Grant Hiura

Grant Hiura

House Staff
Medicine

Selected Publications

The association of area deprivation index and blood pressure control and therapeutic inertia among older adults with hypertension.

Journal Article Journal of human hypertension · November 2025 Neighborhood characteristics may influence patient and clinician management of blood pressure (BP) control. This study examined the association of the Area Deprivation Index (ADI) with uncontrolled BP ( ≥ 140/90 mmHg) at primary care visits and therapeutic ... Full text Cite

Association of Questionnaire-Assessed Fall Risk With Uncontrolled Blood Pressure and Therapeutic Inertia Among Older Adults.

Journal Article Journal of clinical hypertension (Greenwich, Conn.) · January 2025 Therapeutic inertia (TI), or failure to escalate or initiate BP lowering medications when BP is uncontrolled, increases with advancing age and may in part be due to perceived fall risk. This study examined the association of a fall risk assessment, based o ... Full text Cite

Age and sex disparities in blood pressure control and therapeutic inertia: Impact of a quality improvement program.

Journal Article American journal of preventive cardiology · March 2024 ObjectiveHypertension quality improvement programs reduce uncontrolled blood pressure (BP) but impact may differ by sex and age.MethodsThis study examined uncontrolled BP, defined as a BP ≥ 140/90 mmHg, and therapeutic inertia, defined as ... Full text Cite

Age and Comorbidities Are Associated With Therapeutic Inertia Among Older Adults With Uncontrolled Blood Pressure.

Journal Article American journal of hypertension · March 2024 BackgroundLack of initiation or escalation of blood pressure (BP) lowering medication when BP is uncontrolled, termed therapeutic inertia (TI), increases with age and may be influenced by comorbidities.MethodsWe examined the association o ... Full text Cite

Associations of hiatus hernia with CT-based interstitial lung changes: the MESA Lung Study.

Journal Article The European respiratory journal · January 2023 BackgroundHiatus hernia (HH) is prevalent in adults with pulmonary fibrosis. We hypothesised that HH would be associated with markers of lung inflammation and fibrosis among community-dwelling adults and stronger among MUC5B (rs35705950) ri ... Full text Cite

Quantification of lung ventilation defects on hyperpolarized MRI: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study.

Journal Article Magnetic resonance imaging · October 2022 PurposeTo develop an end-to-end deep learning (DL) framework to segment ventilation defects on pulmonary hyperpolarized MRI.Materials and methodsThe Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease (COPD) study ... Full text Cite

Mapping Alveolar Oxygen Partial Pressure in COPD Using Hyperpolarized Helium-3: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study.

Journal Article Tomography (Ann Arbor, Mich.) · September 2022 Chronic obstructive pulmonary disease (COPD) and emphysema are characterized by functional and structural damage which increases the spaces for gaseous diffusion and impairs oxygen exchange. Here we explore the potential for hyperpolarized (HP) 3He MRI to ... Full text Cite

Pulmonary Blood Volume Among Older Adults in the Community: The MESA Lung Study.

Journal Article Circulation. Cardiovascular imaging · August 2022 BackgroundThe pulmonary vasculature is essential for gas exchange and impacts both pulmonary and cardiac function. However, it is difficult to assess and its characteristics in the general population are unknown. We measured pulmonary blood volume ... Full text Cite

Selective serotonin reuptake inhibitors and lung function in the multi-ethnic study of atherosclerosis lung study.

Journal Article Respiratory medicine · May 2022 ObjectiveDepression in patients with Chronic Obstructive Pulmonary Disease (COPD) has been shown to be chronic and potentially increase the burden of symptoms. Selective serotonin reuptake inhibitors (SSRIs) have anti-inflammatory and serotonergic ... Full text Cite

Aortic enlargement in chronic obstructive pulmonary disease (COPD) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study.

Journal Article International journal of cardiology · May 2021 BackgroundThe prevalence of abdominal aortic aneurysm is high in chronic obstructive pulmonary disease (COPD) population. Emphysema involves proteolytic destruction of elastic fibers. Therefore, emphysema may also contribute to thoracic aorta dila ... Full text Cite

UNSUPERVISED CLUSTERING OF AIRWAY TREE STRUCTURES ON HIGH-RESOLUTION CT: THE MESA LUNG STUDY.

Conference Proceedings. IEEE International Symposium on Biomedical Imaging · April 2021 The morphology of the proximal human airway tree is highly variable in the general population, and known variants in airway branching patterns are associated with increased risk of COPD and with polymorphisms in growth factors involved in pulmonary develop ... Full text Cite

Hospital Readmissions After Implementation of a Discharge Care Program for Patients with COVID-19 Illness.

Journal Article Journal of general internal medicine · March 2021 BackgroundThe surge of coronavirus 2019 (COVID-19) hospitalizations in New York City required rapid discharges to maintain hospital capacity.ObjectiveTo determine whether lenient provisional discharge guidelines with remote monitoring aft ... Full text Cite

Hiatal hernia prevalence and natural history on non-contrast CT in the Multi-Ethnic Study of Atherosclerosis (MESA).

Journal Article BMJ open gastroenterology · March 2021 ObjectiveTo determine the prevalence, risk factors and natural history of hiatal hernia (HH) on CT in the general population.Materials and methodsThe Multi-Ethnic Study of Atherosclerosis (MESA) acquired full-lung CT on 3200 subjects, age ... Full text Cite

Malnutrition Diagnosis in Critically Ill Patients Using 2012 Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition Standardized Diagnostic Characteristics Is Associated With Longer Hospital and Intensive Care Unit Length of Stay and Increased In-Hospital Mortality.

Journal Article JPEN. Journal of parenteral and enteral nutrition · February 2020 BackgroundStandardized diagnostic criteria for malnutrition were developed by the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition (AND/ASPEN) in 2012. The criteria as a whole has had little validation, and ... Full text Cite

Unmet needs in the transition to adulthood: 18- to 30-year-old people with hemophilia.

Journal Article American journal of hematology · December 2015 Young adults with hemophilia face unique challenges during the transition to adulthood, including issues associated with switching from pediatric to adult hematology care, building mature interpersonal relationships, and establishing an independent career ... Full text Cite