Overview
I am interested in developing Bayesian statistical methods for comparative effectiveness research, network meta-analysis, causal inference, measurement error, and generalizability. A flexible Bayesian modeling framework enables us to easily integrate different data sources and borrow information adaptively across them. The ultimate goal of my research is to provide comprehensive evidence from multiple data sources for answering clinical and scientific questions in public health and medicine.
Current Appointments & Affiliations
Associate Professor of Biostatistics & Bioinformatics
·
2023 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute
·
2018 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Large Language Models to Estimate CGI-S From Clinical Notes as a Measure of Depression Severity (Preprint)
Preprint · November 2, 2025 Full text CiteBiomarker-guided adaptive enrichment design with threshold detection for clinical trials with time-to-event outcome.
Journal Article J Biopharm Stat · October 2025 Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effec ... Full text Link to item CiteA Bayesian re-analysis of the STRESS trial.
Journal Article Am Heart J · September 25, 2025 BACKGROUND: Prophylactic steroids are often used to reduce the systemic inflammatory response to cardiopulmonary bypass in infants undergoing heart surgery. The STRESS trial found that the odds of a worse outcome did not differ between infants randomized t ... Full text Link to item CiteRecent Grants
Trial of Sequential Medications AfteR TNF failure in JIA (SMART-JIA)
ResearchStatistical Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2024 - 2031Hospital-to-Home Care Coordination for Children and Youth with Special Health Care Needs
Clinical TrialCo Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2024 - 2030Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
ResearchBiostatistician · Awarded by National Institutes of Health · 2025 - 2030View All Grants
Education, Training & Certifications
University of Minnesota, Twin Cities ·
2013
Ph.D.
Harvard University ·
2010
M.S.