Overview
I am interested in developing Bayesian statistical methods for comparative effectiveness research, network meta-analysis, causal inference, measurement error, and generalizability. A flexible Bayesian modeling framework enables us to easily integrate different data sources and borrow information adaptively across them. The ultimate goal of my research is to provide comprehensive evidence from multiple data sources for answering clinical and scientific questions in public health and medicine.
Current Appointments & Affiliations
Associate Professor of Biostatistics & Bioinformatics
·
2023 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute
·
2018 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Biomarker-guided adaptive enrichment design with threshold detection for clinical trials with time-to-event outcome.
Journal Article J Biopharm Stat · April 20, 2025 Biomarker-guided designs are increasingly used to evaluate personalized treatments based on patients' biomarker status in Phase II and III clinical trials. With adaptive enrichment, these designs can improve the efficiency of evaluating the treatment effec ... Full text Link to item CiteNetwork Meta-Analysis With Individual Participant-Level Data of Time-to-Event Outcomes Using Cox Regression.
Journal Article Stat Med · February 28, 2025 The accessibility of individual participant-level data (IPD) enhances the evaluation of moderation effects of patient covariates. It facilitates the provision of accurate estimation of intervention effects and confidence intervals by incorporating covariat ... Full text Link to item CiteUsing Parks and Recreation Providers to Enhance Obesity Treatment: A Randomized Controlled Trial.
Journal Article Pediatrics · February 10, 2025 OBJECTIVE: Intensive health behavior and lifestyle treatment (IHBLT) is recommended for children aged 6-18 years with obesity. The objective was to evaluate the effectiveness of Fit Together, a health care and parks and recreation partnership to deliver IH ... Full text Link to item CiteRecent Grants
Hospital-to-Home Care Coordination for Children and Youth with Special Health Care Needs
Clinical TrialCo Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2024 - 2030Trial of Sequential Medications AfteR TNF failure in JIA (SMART-JIA)
ResearchStatistical Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2024 - 2030Impact of Integrated Pet Care on Glycemic Control and Diabetes Responsibility
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2027View All Grants
Education, Training & Certifications
University of Minnesota, Twin Cities ·
2013
Ph.D.
Harvard University ·
2010
M.S.