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James Topping

Bioinformatician, Senior
Duke Clinical Research Institute
Box 3850 Med Ctr, Durham, NC
300 W Morgan St, Suite 800, Durham, NC 27701

Current Duke Appointments & Affiliations


Recent Scholarly Works


Standardizing, harmonizing, and protecting data collection to broaden the impact of COVID-19 research: the rapid acceleration of diagnostics-underserved populations (RADx-UP) initiative.

Journal article J Am Med Inform Assoc · August 16, 2022 OBJECTIVE: The Rapid Acceleration of Diagnostics-Underserved Populations (RADx-UP) program is a consortium of community-engaged research projects with the goal of increasing access to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests in un ... Full text Link to item Cite

Improving and sustaining the site investigator community: Recommendations from the Clinical Trials Transformation Initiative.

Journal article Contemp Clin Trials Commun · December 2019 The Clinical Trials Transformation Initiative (CTTI) Strengthening the Investigator Community Project was prompted by the need to understand the reasons for high rates of turnover among investigators who lead US Food and Administration-regulated clinical t ... Full text Link to item Cite

Trends in clinical trial investigator workforce and turnover: An analysis of the U.S. FDA 1572 BMIS database.

Journal article Contemp Clin Trials Commun · September 2019 BACKGROUND: High turnover rates among clinical trial investigators contribute to inefficiency, instability, and increased costs for the clinical research enterprise; however, factors contributing to investigator turnover have not been well characterized. M ... Full text Link to item Cite
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Recent Grants


PTN LAP01 Registry

ResearchInformatics Analyst · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2021 - 2026

RADx-UP CDCC

ResearchInformatics Analyst · Awarded by National Institutes of Health · 2020 - 2025

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