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John J. Strouse

Associate Professor of Medicine
Medicine, Hematology

Overview


My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults and the functional evaluation of adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

Current Appointments & Affiliations


Associate Professor of Medicine · 2025 - Present Medicine, Hematology, Medicine
Associate Professor in the Department of Pediatrics · 2018 - Present Pediatrics, Hematology-Oncology, Pediatrics

In the News


Published April 25, 2024
How Climate Change Is Affecting Health

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Recent Publications


Hydroxyurea for Children with Sickle Cell Disease: A Practical Guide for Pediatric Clinicians.

Journal Article Pediatr Clin North Am · February 2026 Hydroxyurea is the cornerstone therapy for children with sickle cell disease (SCD). Children with sickle cell anemia (SCA; ∼64% of children with SCD) should be started on hydroxyurea as infants and continue treatment throughout childhood. Hydroxyurea reduc ... Full text Link to item Cite

Role of Menstrual Bleeding Assessments in Sickle Cell Clinics.

Journal Article JAMA Netw Open · December 1, 2025 IMPORTANCE: The interplay between sickle cell disease (SCD) and reproductive health remains understudied. Menstruation is particularly complex in individuals with SCD, who may have delayed puberty, early menopause, abnormal uterine bleeding, and overlappin ... Full text Link to item Cite

Enhancing Communication and Trust in Advance Care Planning for Older Adults with Sickle Cell Disease

Conference Innovation in Aging · December 1, 2025 AbstractDespite advancements in treatments, life expectancy for sickle cell disease (SCD) remains 20 years shorter than people without SCD, making advance care planning (ACP) important. There is a gap in ... Full text Cite
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Recent Grants


DISC 3405-102

Clinical TrialPrincipal Investigator · Awarded by Disc Medicine Inc. · 2026 - 2030

Advancing a Holistic Understanding of Variability in Lived Experience with Sickle Cell Pain

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2030

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Education


Johns Hopkins University · 2009 Ph.D.
Johns Hopkins University, School of Medicine · 1996 M.D.