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Julia Dawn Visgauss

Assistant Professor of Orthopaedic Surgery
Orthopaedic Surgery

Overview


I specialize in pelvic resection and reconstructive surgery.  I have a special interest in researching and understanding how people’s gait is affected by pelvic surgery, and how we can improve reconstructive techniques in order to optimally balance restoration of anatomy and function.

My translational research is focused on understanding what drives disease progression and treatment resistance in sarcoma.  Currently my focus is in chondrosarcoma, a subtype of bone sarcoma that produces cartilage, and has extremely limited treatment options beyond surgery.  My lab is working to uncover the cellular derangements and immune interactions that allow these cells to metastasize, and develop targeted systemic therapies to improve patient outcomes.

Current Appointments & Affiliations


Assistant Professor of Orthopaedic Surgery · 2021 - Present Orthopaedic Surgery, Clinical Science Departments
Member of the Duke Cancer Institute · 2019 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Novel niclosamide stearate prodrug therapeutic shows potential efficacy against naturally occurring canine osteosarcoma in a clinical feasibility study.

Journal Article Am J Vet Res · January 1, 2026 OBJECTIVE: To manufacture and characterize a modified niclosamide stearate (NS) prodrug therapeutic (mNSPT) for use in a small clinical trial in a metastatic canine osteosarcoma (OS) model. ANIMALS: 10 dogs that presented for treatment of nondetectable met ... Full text Link to item Cite

The impact of preoperative bone mineral density on outcomes following lower extremity megaprosthetic reconstruction for oncologic resections.

Journal Article Bone · January 2026 BACKGROUND: While megaprosthetic reconstructions have been instrumental in restoring patients' functional abilities, surgeons remain cautious of revision risk. This is the first study to assess the impacts of preoperative bone mineral density (BMD) on outc ... Full text Link to item Cite

Financial Toxicity among Survivors of Extremity and Pelvic Sarcoma: A Retrospective Study.

Journal Article Ann Surg Oncol · November 13, 2025 BACKGROUND: Financial toxicity in oncology, defined as the economic burden and psychosocial distress of cancer care, has been associated with poor clinical outcomes. Despite high projected treatment costs, data on financial toxicity in patients with sarcom ... Full text Link to item Cite
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Recent Grants


Defining and targeting CIC::DUX4-dependent survival in fusion-positive sarcomas

FellowshipCollaborator · Awarded by National Institutes of Health · 2025 - 2028

Investigating drivers and therapeutic approaches for LCP1 overexpression in chondrosarcoma

ResearchPrincipal Investigator · Awarded by The Musculoskeletal Tumor Society · 2024 - 2026

Fresh Tissue Lab

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Onkos Surgical, Inc · 2025 - 2025

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Education, Training & Certifications


Johns Hopkins University, School of Medicine · 2012 M.D.