Current Appointments & Affiliations
Research Associate, Senior
Neurobiology,
Basic Science Departments
Recent Publications
Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling.
Journal Article Dev Cell · October 23, 2023 During nervous system development, neurons choose synaptic partners with remarkable specificity; however, the cell-cell recognition mechanisms governing rejection of inappropriate partners remain enigmatic. Here, we show that mouse retinal neurons avoid in ... Full text Link to item CiteCiliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses.
Journal Article International journal of molecular sciences · June 2022 The Unc119 protein mediates transport of myristoylated proteins to the photoreceptor outer segment, a specialized primary cilium. This transport activity is regulated by the GTPase Arl3 as well as by Arl13b and Rp2 that control Arl3 activation/inactivation ... Full text CiteEarly Changes in Exo- and Endocytosis in the EAE Mouse Model of Multiple Sclerosis Correlate with Decreased Synaptic Ribbon Size and Reduced Ribbon-Associated Vesicle Pools in Rod Photoreceptor Synapses.
Journal Article International journal of molecular sciences · October 2021 Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that finally leads to demyelination. Demyelinating optic neuritis is a frequent symptom in MS. Recent studies also revealed synapse dysfunctions in MS patients and MS mouse mo ... Full text CiteRecent Grants
Molecular and cellular requirements for Crb1 gene function in the onset and therapeutic rescue of an inherited retinal degeneration
ResearchSenior Research Associate · Awarded by National Eye Institute · 2024 - 2028Precise assembly of retinal circuitry through rejection of inappropriate synaptic partners
ResearchPostdoctoral Associate · Awarded by National Eye Institute · 2021 - 2025View All Grants