Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Research Associate, Pharmacology, University of North Carolina at Chapel Hill 2013 - 2018
  • Ph.D., University of Washington 2011
• Research
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  Selected Grants

  • Immunogen Design Strategies To Direct Hiv-1 Broadly Neutralizing Antibody Maturation By Probability-Based Targeting Of Critical Mutations awarded by National Institutes of Health 2019 - 2020
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Azoitei, Mihai L., Jungsik Noh, Daniel J. Marston, Philippe Roudot, Christopher B. Marshall, Timothy A. Daugird, Sidney L. Lisanza, et al. “Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways.” J Cell Biol 218, no. 9 (September 2, 2019): 3077–97. https://doi.org/10.1083/jcb.201812073.
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    • O’Shaughnessy, Ellen C., Orrin J. Stone, Paul K. LaFosse, Mihai L. Azoitei, Denis Tsygankov, John M. Heddleston, Wesley R. Legant, et al. “Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor.” J Cell Biol 218, no. 9 (September 2, 2019): 3153–60. https://doi.org/10.1083/jcb.201903019.
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    • Azoitei, M. L., Y. A. Ban, O. Kalyuzhny, J. Guenaga, A. Schroeter, J. Porter, R. Wyatt, and William R. Schief. “Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5.” Proteins 82, no. 10 (October 2014): 2770–82. https://doi.org/10.1002/prot.24641.
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    • Azoitei, Mihai L., Yih-En Andrew Ban, Jean-Philippe Julien, Steve Bryson, Alexandria Schroeter, Oleksandr Kalyuzhniy, Justin R. Porter, et al. “Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.” J Mol Biol 415, no. 1 (January 6, 2012): 175–92. https://doi.org/10.1016/j.jmb.2011.10.003.
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    • Azoitei, Mihai L., Bruno E. Correia, Yih-En Andrew Ban, Chris Carrico, Oleksandr Kalyuzhniy, Lei Chen, Alexandria Schroeter, et al. “Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.” Science 334, no. 6054 (October 21, 2011): 373–76. https://doi.org/10.1126/science.1209368.
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    • Carter, Laura L., Michael W. Leach, Mihai L. Azoitei, Junqing Cui, Jeffrey W. Pelker, Jason Jussif, Steve Benoit, et al. “PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.” J Neuroimmunol 182, no. 1–2 (January 2007): 124–34. https://doi.org/10.1016/j.jneuroim.2006.10.006.
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    • Marusic, Suzana, Michael W. Leach, Jeffrey W. Pelker, Mihai L. Azoitei, Naonori Uozumi, Junqing Cui, Marina W. H. Shen, et al. “Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.” J Exp Med 202, no. 6 (September 19, 2005): 841–51. https://doi.org/10.1084/jem.20050665.
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  • Conference Papers

    • Azoitei, M. L., J. Noh, M. J. Sandi, P. Roudot, R. K. Rottapel, G. Danuser, and K. M. Hahn. “Novel biosensor reveals the regulation and coordination of GEF-H1 with protrusion machinery.” In Molecular Biology of the Cell, Vol. 28. AMER SOC CELL BIOLOGY, 2017.
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