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Rana K. Gupta

W. David and Sarah W. Stedman Distinguished Professor
Medicine, Endocrinology, Metabolism, and Nutrition

Current Appointments & Affiliations


W. David and Sarah W. Stedman Distinguished Professor · 2023 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Professor in Medicine · 2022 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Professor in Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Member of Duke Molecular Physiology Institute · 2022 - Present Duke Molecular Physiology Institute, Institutes and Centers

In the News


Published May 4, 2023
Duke Awards 44 Distinguished Professorships
Published December 7, 2022
Listening in on the Conversations of Fat Cells

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Recent Publications


The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.

Journal Article Diabetes · May 2024 Body fat distribution is a predictor of metabolic health in obesity. In this Classics in Diabetes article, we revisit a 1985 Diabetes article by Swedish investigators Ohlson et al. This work was one of the first prospective population-based studies that es ... Full text Cite

GPR84-mediated signal transduction affects metabolic function by promoting brown adipocyte activity.

Journal Article J Clin Invest · December 15, 2023 The G protein-coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has garnered attention because of its potential involvement in a range of metabolic conditions. However, the precise mechanisms underlying this effect remain elusive. Our study ... Full text Link to item Cite

Protocol for quantitative proteomic analysis of heterogeneous adipose tissue-residing progenitor subpopulations in mice.

Journal Article STAR Protoc · December 15, 2023 Recent studies have revealed cellular heterogeneity of mesenchymal stromal cells and immune cells in adipose tissue and emphasized the need for quantitative analysis of small numbers of functionally distinct cells using state-of-the-art "omics" technologie ... Full text Link to item Cite
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Recent Grants


Endocrinology and Metabolism Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

Elucidating the Transcriptional Brakes on Adipocyte Thermogenesis

FellowshipPrincipal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2023 - 2028

Adaptations of the Adipose Tissue Mesothelium in Diet-Induced Obesity

FellowshipPrincipal Investigator · Awarded by American Diabetes Association · 2025 - 2027

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Education, Training & Certifications


University of Pennsylvania · 2006 Ph.D.