Scholars@Duke
Richa Agarwal

Richa Agarwal

Associate Professor of Medicine
Medicine, Cardiology
richa.agarwal@duke.edu
2301 Erwin Rd, DUMC Box 3126, Durham, NC 27710

Selected Publications

Pre-operative atrial fibrillation and early right ventricular failure after left ventricular assist device implantation: a systematic review and meta-analysis.

Journal Article Am Heart J · September 2021 BACKGROUND: Right ventricular failure (RVF) remains a major cause of morbidity and mortality after left ventricular assist device (LVAD). Atrial fibrillation (AF) is known for its deleterious effects on cardiac function and hemodynamics. The association of ... Full text Link to item Cite

Phosphodiesterase-5 Inhibitors and Outcomes During Left Ventricular Assist Device Support: A Systematic Review and Meta-Analysis.

Journal Article J Card Fail · April 2021 BACKGROUND: Phosphodiesterase-5 inhibitors (PDE5i) have been used to treat pulmonary hypertension and right ventricular failure in patients with left ventricular assist devices (LVAD). The effects of PDE5i on post-LVAD outcomes including hemocompatibility- ... Full text Open Access Link to item Cite

Biomarkers in Advanced Heart Failure: Implications for Managing Patients With Mechanical Circulatory Support and Cardiac Transplantation.

Journal Article Circ Heart Fail · July 2020 Biomarkers have a well-defined role in the diagnosis and management of chronic heart failure, but their role in patients with left ventricular assist devices and cardiac transplant is uncertain. In this review, we summarize the available literature in this ... Full text Link to item Cite

Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.

Journal Article Circ Heart Fail · April 2020 BACKGROUND: Palliative care improves quality of life in patients with heart failure. Whether men and women with heart failure derive similar benefit from palliative care interventions remains unknown. METHODS: In a secondary analysis of the PAL-HF trial (P ... Full text Link to item Cite

Predictors and Outcomes of Hemodynamic and Functional LVAD Non-Responders: An Analysis of the INTERMACS Registry

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Despite recent advancements in left ventricular assist device (LVAD) technology, there remains a population of patients who experience ongoing signs and symptoms of heart failure during LVAD support. We sought to describe risk factors and outcomes ... Full text Cite

Impact of Pulse Pressure on Hemocompatibility Related Adverse Events during Support with Continuous Flow Left Ventricular Assist Devices: An Analysis of the INTERMACS Registry

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: While the impact of mean arterial pressure (MAP) on adverse events during left ventricular assist device (LVAD) support has been well established, there remains significant controversy regarding the impact of pulse pressure (PP) on clinical outcom ... Full text Cite

Bloodstream Infections in Continuous Flow Left Ventricular Assist Device Recipients: Diagnostic and Clinical Implications

Journal Article ASAIO Journal · November 2019 Bloodstream infection (BSI) is a common complication of left ventricular assist device (LVAD) support and particularly difficult to treat. The presentation is often variable because of altered physiology and augmentation of cardiac output by the de ... Full text Cite

Clinical Experience of HeartMate II to HeartWare Left Ventricular Assist Device Exchange: A Multicenter Experience.

Journal Article Ann Thorac Surg · October 2019 BACKGROUND: Despite improvements in pump design and durability, left ventricular assist device patients still suffer from life-threatening complications such as pump thrombosis (PT) and infection, often necessitating device exchange. Surgical exchange from ... Full text Link to item Cite

Early intervention for lactate dehydrogenase elevation improves clinical outcomes in patients with the HeartMate II left ventricular assist device: Insights from the PREVENT study.

Journal Article J Heart Lung Transplant · January 2018 BACKGROUND: Hemolysis, assessed by elevated serum lactate dehydrogenase (LDH), is strongly associated with HeartMate II pump thrombosis (PT). However, it is unknown whether early intervention for elevated LDH circumvents the risk of serious PT requiring pu ... Full text Link to item Cite

Hemodynamic Response to Treatment of Iron Deficiency Anemia in Pulmonary Arterial Hypertension: Longitudinal Insights from an Implantable Hemodynamic Monitor

Journal Article Pulmonary Circulation · December 2016 Despite new therapeutic options, pulmonary arterial hypertension (PAH) remains a progressive disease associated with substantial morbidity and mortality. As such, additional strategies for monitoring and adjunctive management of this disease are im ... Full text Open Access Cite

Macitentan (Opsumit) for the treatment of pulmonary arterial hypertension

Journal Article Expert Review of Clinical Pharmacology · July 2014 Full text Open Access Cite

Prognostication in Pulmonary Arterial Hypertension

Journal Article Heart Failure Clinics · July 2012 Full text Open Access Cite