Richard Harry Weisler

Journal Article CNS Drugs · August 2017 OBJECTIVE: The objective of this randomized, double-blind, placebo-controlled study was to evaluate the efficacy and safety of SHP465 mixed amphetamine salts (MAS) in adults with attention-deficit/hyperactivity disorder (ADHD). METHODS: Eligible adults [ag ... Full text Link to item Cite

Brexpiprazole as an adjunctive treatment in young adults with major depressive disorder who are in a school or work environment.

Journal Article J Affect Disord · November 1, 2016 BACKGROUND: Major depressive disorder (MDD) is a common, debilitating disorder with substantial socioeconomic burden. Many patients with MDD experience symptoms that impair functioning and productivity, often negatively affecting work or educational pursui ... Full text Link to item Cite

Efficacy of extended release quetiapine fumarate monotherapy in patients with major depressive disorder: a pooled analysis of two 6-week, double-blind, placebo-controlled studies.

Journal Article Int Clin Psychopharmacol · January 2012 Prospectively planned pooled analysis evaluating the efficacy of quetiapine extended release (XR) monotherapy in major depressive disorder (MDD). Data were pooled from two 6-week, randomized, double-blind, placebo-controlled studies of quetiapine XR in out ... Full text Link to item Cite

Discovery and development of lamotrigine for bipolar disorder: a story of serendipity, clinical observations, risk taking, and persistence.

Journal Article J Affect Disord · May 2008 This paper briefly reviews and comments on the development of lamotrigine as a treatment for bipolar disorder. The events described include astute clinical observations by epileptologists, serendipitous coupling of the drug's clinical profile to unmet need ... Full text Link to item Cite

Emerging drugs for attention-deficit/hyperactivity disorder.

Journal Article Expert Opin Emerg Drugs · September 2007 Symptoms of attention-deficit/hyperactivity disorder (ADHD) are heterogeneous and often accompanied by comorbid psychiatric disorders. Although symptoms tend to lessen with age, many patients continue to be affected by the disorder into adulthood. Although ... Full text Link to item Cite

Review of long-acting stimulants in the treatment of attention deficit hyperactivity disorder.

Journal Article Expert Opin Pharmacother · April 2007 A number of long-acting medications for the treatment of attention deficit hyperactivity disorder (ADHD) have recently been developed and approved for use in the US. These compounds are intended to optimize and maintain ADHD symptom control throughout the ... Full text Link to item Cite

The use of antiepileptic drugs in bipolar disorders: a review based on evidence from controlled trials.

Journal Article CNS Spectr · October 2006 Antiepileptic drugs (AEDs) have diverse psychotropic profiles. Some AEDs have proven to be efficacious in the treatment of mood disorders, especially bipolar disorder. Others are ineffective as primary treatments but may be useful adjuncts for mood disorde ... Full text Link to item Cite

Mental health and recovery in the Gulf Coast after Hurricanes Katrina and Rita.

Journal Article JAMA · August 2, 2006 Full text Link to item Cite

Mixed amphetamine salts extended-release in the treatment of adult ADHD: a randomized, controlled trial.

Journal Article CNS Spectr · August 2006 INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is a serious neurobehavioral disorder of childhood onset that often persists into adolescence and adulthood. Functional impairments, underachievement, and difficult interpersonal relationships i ... Full text Link to item Cite

Carbamazepine extended-release capsules in bipolar disorder.

Journal Article Neuropsychiatr Dis Treat · March 2006 Carbamazepine (CBZ) has long been a therapeutic option for bipolar disorder. Carbamazepine extended-release capsules (CBZ-ERC) are a recent formulation of CBZ approved by the US Food and Drug Administration in 2004 for the treatment of acute manic and mixe ... Link to item Cite

Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials.

Journal Article CNS Drugs · 2006 OBJECTIVES: Recently, two large, 3-week, randomised, double-blind, placebo-controlled trials using nearly identical protocols demonstrated that monotherapy with carbamazepine extended-release capsules (CBZ-ERC) was effective for the treatment of acute mani ... Full text Link to item Cite

Long-term cardiovascular effects of mixed amphetamine salts extended release in adults with ADHD.

Journal Article CNS Spectr · December 2005 OBJECTIVE: To assess long-term cardiovascular effects of mixed amphetamine salts extended release (MAS XR) in adults with attention-deficit/hyperactivity disorder (ADHD) combined subtype. METHODS: 223 otherwise healthy adults (>or=18 years of age) with ADH ... Full text Link to item Cite

Carbamazepine extended-release capsules: a new treatment option for bipolar I disorder.

Journal Article Expert Rev Neurother · September 2005 Carbamazepine has a long history in psychiatry and neurology. More recently, carbamazepine extended-release capsules have been approved by the US Food and Drug Administration for the treatment of manic and mixed episodes associated with bipolar I disorder. ... Full text Link to item Cite

Safety, efficacy and extended duration of action of mixed amphetamine salts extended-release capsules for the treatment of ADHD.

Journal Article Expert Opin Pharmacother · June 2005 Stimulant medications have proven to be effective in reducing the core symptoms of hyperactivity, impulsivity and inattention and are considered the first line of therapy for patients with attention-deficit/hyperactivity disorder (ADHD). Mixed amphetamine ... Full text Link to item Cite

Extended-release carbamazepine capsules as monotherapy for acute mania in bipolar disorder: a multicenter, randomized, double-blind, placebo-controlled trial.

Journal Article J Clin Psychiatry · March 2005 BACKGROUND: Although carbamazepine has long been used for the treatment of acute mania, only recently was its efficacy confirmed in a large, multicenter, parallel-group, placebo-controlled, randomized trial. In the present study, we further evaluated the e ... Full text Link to item Cite

A multicenter, randomized, double-blind, placebo-controlled trial of extended-release carbamazepine capsules as monotherapy for bipolar disorder patients with manic or mixed episodes.

Journal Article J Clin Psychiatry · April 2004 BACKGROUND: Carbamazepine has been used to treat mania for over 2 decades. Most evaluations of carbamazepine have had important limitations, such as absence of a parallel placebo group, small sample size, or the confounding influence of concomitant treatme ... Full text Link to item Cite