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Selected Publications

Effect of adrenocorticotropic hormone infusion on circulating sclerostin levels.

Journal Article Endocr Connect · December 14, 2021 Glucocorticoid use is the most common cause of secondary osteoporosis. Poor skeletal health related to glucocorticoid use is thought to involve inhibition of the Wnt/β-catenin signaling pathway, a key pathway in osteoblastogenesis. Sclerostin, a peptide pr ... Full text Link to item Cite

Disentangling the Relationships Between the Renin-Angiotensin-Aldosterone System, Calcium Physiology, and Risk for Kidney Stones.

Journal Article J Clin Endocrinol Metab · June 1, 2020 CONTEXT: Complex relationships between aldosterone and calcium homeostasis have been proposed. OBJECTIVE: To disentangle the influence of aldosterone and intravascular volume on calcium physiology. DESIGN: Patient-oriented and epidemiology studies. SETTING ... Full text Link to item Cite

A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes.

Journal Article J Renin Angiotensin Aldosterone Syst · 2018 BACKGROUND: Prior studies suggest that vitamin D therapy may decrease cardiovascular disease risk in type 2 diabetes (T2DM) by lowering renin-angiotensin system (RAS) activity. However, randomized human intervention studies to evaluate the effect of vitami ... Full text Link to item Cite

Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney Function.

Journal Article J Clin Endocrinol Metab · April 1, 2017 CONTEXT: Obesity is associated with poor bone mineralization and quality. Fibroblast growth factor 23 (FGF23) plays an important role in skeletal physiology. OBJECTIVE: To test hypothesis that greater adiposity results in higher FGF23 levels among individu ... Full text Link to item Cite

Angiotensin-Converting Enzyme Inhibition and Parathyroid Hormone Secretion.

Journal Article Int J Endocrinol · 2017 BACKGROUND: Prior studies suggest that renin-angiotensin-aldosterone system (RAAS) inhibitors decrease parathyroid hormone (PTH) secretion. OBJECTIVE: To evaluate the effect of angiotensin-converting enzyme inhibitors (ACEi) on serum PTH in participants wi ... Full text Link to item Cite

Parathyroid Hormone and the Use of Diuretics and Calcium-Channel Blockers: The Multi-Ethnic Study of Atherosclerosis.

Journal Article J Bone Miner Res · June 2016 Thiazide diuretic (TZ) use is associated with higher bone mineral density, whereas loop diuretic (LD) use is associated with lower bone density and incident fracture. Dihydropyridine-sensitive calcium channels are expressed on parathyroid cells and may pla ... Full text Link to item Cite

Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome.

Journal Article Cardiovasc Intervent Radiol · October 2015 Bilateral adrenalectomy is currently the only available treatment for adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome (ectopic ACTH syndrome) that is refractory to pharmacologic therapy. We describe two patients with refractory ectopic ACTH ... Full text Link to item Cite

Denosumab for the treatment of osteoporosis.

Journal Article Expert Opin Drug Metab Toxicol · March 2015 INTRODUCTION: Low trauma fractures due to osteoporosis are a major health concern worldwide. Despite the availability of many therapeutic compounds to reduce fracture risk, osteoporosis remains undertreated and the burden of osteoporotic fractures remains ... Full text Link to item Cite