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Saratchandra Singh Khumukcham

Postdoctoral Associate
Medicine, Gastroenterology

Current Duke Appointments & Affiliations


Postdoctoral Associate Medicine, Gastroenterology, Medicine

Recent News Items


Published March 18, 2026
Duke GI Researcher Included in Video Featuring Immunotherapy Clinical Tria

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Recent Scholarly Works


Aging restricts colorectal tumor growth by epigenetically silencing developmental gene programs

Preprint · June 15, 2026 The incidence of early-onset colorectal cancer (CRC) has risen sharply in recent decades1, yet the biological basis underlying the distinct behavior of tumors arising in young versus aged tissues remains poorly understood. Here we show that aging r ... Full text Cite

Abstract 2799: Tumoral IL-33/ST2 signaling drives immune escape through reduced antigen presentation

Conference Cancer Research · April 3, 2026 AbstractThe majority (up to 85%) of colorectal cancer (CRC) patients have a microsatellite stable (MSS) tumor phenotype, which is a poor responder to immune checkpoint blockade (ICB). Therefore, there is ... Full text Cite

Decoding Rho GTPase signalling networks in directed cell migration.

Journal article Frontiers in cell and developmental biology · January 2026 Small G proteins are molecular switches in the realm of cell biology, switching from the GTP-bound active form to the GDP-bound inactive form. They participate in controlling various essential cellular functions, one of which is cell migration. Cell migrat ... Full text Cite
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Recent Grants


Role and regulation of asparagine in colorectal cancer

ResearchPostdoctoral Associate · Awarded by Yale University · 2025 - 2029

Mitigation of gastrointestinal acute radiation syndrome by promoting clusterin-mediated intestinal regeneration

ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

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