Scholars@Duke
Sonya Mansukhlal Kothadia

Sonya Mansukhlal Kothadia

Assistant Professor of Medicine
Medicine, Infectious Diseases
sk141@duke.edu
2424 Erwin Road, BOX_2714 Med Ctr, Durham, NC 27705

Selected Publications

Application of plasma cell-free metagenomic next-generation sequencing for the identification of Aspergillus fumigatus donor-derived infections among solid organ transplant recipients.

Journal Article Med Mycol Case Rep · December 2025 A cluster of Aspergillus fumigatus donor-derived infections (DDI) was rapidly diagnosed using plasma metagenomic next-generation sequencing (mNGS) among solid organ transplant recipients. The heart recipient, experiencing marginal hemodynamics, underwent a ... Full text Link to item Cite

Impact of HeartMate 3 left ventricular assist device infection on outcomes following heart transplant.

Journal Article J Heart Lung Transplant · November 13, 2025 BACKGROUND: Infectious complications are common in patients implanted with HeartMate 3 (HM3) left ventricular assist devices (LVAD). Despite these issues, some patients with LVAD-specific infection are ultimately considered for heart transplant (HT). The i ... Full text Link to item Cite

Outcomes of lung transplantation from SARS-CoV-2 positive donors during the Omicron wave.

Journal Article JHLT Open · May 2025 Early observations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) transmission via lung transplantation have led to frequent discard of lungs from donors with positive SARS-CoV-2 tests. We compared survival between lung transplant recipien ... Full text Link to item Cite

Outcomes of CMV infection in the setting of gastrointestinal graft-vs.-host disease in the era of pre-emptive and prophylactic antiviral therapy.

Journal Article Transpl Immunol · May 2025 BACKGROUND: Concurrent cytomegalovirus infection (CMVi) and gastrointestinal graft-versus-host disease (GI-GVHD) poses significant risks for increased morbidity and mortality in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). ... Full text Link to item Cite

Clinical outcomes of lung transplant recipients with pre-transplant Mycobacterium avium complex infection

Conference Transplant Infectious Disease · October 1, 2024 Background: Lung transplant recipients (LTRs) are at risk for Mycobacterium avium complex (MAC) infections, in part due to the presence of structural lung disease pre-transplant and relatively higher levels of immunosuppression post-transplant. There is a ... Full text Cite

Clinical outcomes of lung transplant recipients with pre-transplant Mycobacterium avium complex infection.

Journal Article Transpl Infect Dis · October 2024 BACKGROUND: Lung transplant recipients (LTRs) are at risk for Mycobacterium avium complex (MAC) infections, in part due to the presence of structural lung disease pre-transplant and relatively higher levels of immunosuppression post-transplant. There is a ... Full text Link to item Cite

Impact of Mandatory Infectious Disease Specialist Approval on Hospital-Onset Clostridioides difficile Infection Rates and Testing Appropriateness.

Journal Article Clin Infect Dis · August 14, 2023 BACKGROUND: Inappropriate Clostridioides difficile testing is common in the hospital setting, leading to potential overdiagnosis of infection when single-step nucleic acid amplification testing is used. The potential role of infectious diseases (ID) specia ... Full text Link to item Cite

Neither Race nor Ethnicity Impact the Mortality of Residents of Veterans Affairs Community Living Center With COVID-19.

Journal Article J Am Med Dir Assoc · January 2023 OBJECTIVES: COVID-19 disproportionately affected nursing home residents and people from racial and ethnic minorities in the United States. Nursing homes in the Veterans Affairs (VA) system, termed Community Living Centers (CLCs), belong to a national manag ... Full text Link to item Cite

Impact of fever thresholds in detection of COVID-19 in Department of Veterans Affairs Community Living Center residents.

Journal Article J Am Geriatr Soc · November 2021 BACKGROUND: Among nursing home residents, for whom age and frailty can blunt febrile responses to illness, the temperature used to define fever can influence the clinical recognition of COVID-19 symptoms. To assess the potential for differences in the defi ... Full text Link to item Cite

Appropriateness of C. difficile Testing With Clinical Support Tool Versus Mandatory Infectious Diseases Attending Approval

Conference Infection Control & Hospital Epidemiology · October 2020 Background: In an effort to reduce inappropriate testing of hospital-onset Clostridioides difficile infection (HO-CDI), we sequentially implemented 2 strategies: an electronic health record-based cl ... Full text Cite

Photoactivated phytochromes interact with HEMERA and promote its accumulation to establish photomorphogenesis in Arabidopsis.

Journal Article Genes Dev · August 15, 2012 Plant development is profoundly regulated by ambient light cues through the red/far-red photoreceptors, the phytochromes. Early phytochrome signaling events include the translocation of phytochromes from the cytoplasm to subnuclear domains called photobodi ... Full text Link to item Cite