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Tara Albrecht

Associate Professor in the School of Nursing
School of Nursing
307 Trent Dr, DUMC 3322, Durham, NC 27710
307 Trent Dr, DUMC 3322, Durham, NC 27710

Selected Publications


The association between the gut microbiome and fatigue in individuals living with cancer: a systematic review.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · April 2024 PurposeFatigue is the most distressing symptom for individuals with cancer. While numerous studies have investigated biological pathways that could underlie the mechanism of fatigue, the cause of fatigue remains unclear. This review aimed to inves ... Full text Cite

"I don't have a choice but to keep getting up and doing the things that protect her": The informal caregiver's adaptation to the cancer diagnosis.

Journal Article Journal of psychosocial oncology · February 2024 PurposePatients with hematologic malignancies (HM) typically rely on informal caregivers for support. Caregivers experience distress, poorer health, and lower quality of life. This study aimed to understand caregivers' experiences adapting to, and ... Full text Cite

Crossroads of parental decision making: Intersections of hope, communication, relationships, and emotions.

Journal Article Journal of child health care : for professionals working with children in the hospital and community · June 2023 Parents of children born with complex life-threatening chronic conditions (CLTCs) experience an uncertain trajectory that requires critical decision making. Along this trajectory, hope plays an influential but largely unexplored role; therefore, this quali ... Full text Cite

THE IMPORTANCE OF ENGAGING CLINIC NURSES IN NURSING RESEARCH

Conference ONCOLOGY NURSING FORUM · 2023 Cite

How Caregivers Cope and Adapt When a Family Member Is Diagnosed With a Hematologic Malignancy: Informing Supportive Care Needs.

Journal Article Cancer nursing · November 2022 BackgroundInformal family caregivers (FCs) of adults with various diseases including hematologic malignancy (HM) experience low quality of life and psychological well-being. Although HMs are life-threatening cancers associated with high mortality, ... Full text Cite

Impact of a Hematologic Malignancy Diagnosis and Treatment on Patients and Their Family Caregivers.

Journal Article Oncology nursing forum · August 2022 ObjectivesHematologic malignancies (HMs) are life-threatening cancers that frequently entail aggressive, long, inpatient treatment protocols. This can result in numerous concurrent symptoms and decreased quality of life for patients and can affect ... Full text Cite

The relationship between emotional well-being and understanding of prognosis in patients with acute myeloid leukemia (AML).

Journal Article Support Care Cancer · January 2022 PURPOSE: Adults with acute myeloid leukemia (AML) face considerable distress and often have a poor prognosis. However, little is known about these patients' perceptions of prognosis and how this relates to emotional well-being (EWB). METHODS: We conducted ... Full text Link to item Cite

Oral adherence in adults with acute myeloid leukemia (AML): results of a mixed methods study.

Journal Article Support Care Cancer · November 2020 INTRODUCTION: The incidence of AML is increasing, in part due to an aging population. Since 2017, eight novel agents have been introduced, 6 of which are oral: midostaurin, enasidenib, ivosidenib, gilteritinib, glasdegib, and venetoclax. With an increase i ... Full text Link to item Cite

Psychological and Financial Distress Management in Adults With Acute Leukemia.

Journal Article Seminars in oncology nursing · December 2019 ObjectivesTo review and summarize psychological and financial distress in adults with acute leukemia and provide evidence-based methods that nurses can apply to alleviate distress experienced by patients.Data sourcesOncology and palliativ ... Full text Cite

Cancer-Related Distress and Unmet Needs Among Acute Myeloid Leukemia Survivors

Conference Blood · November 13, 2019 Background: Individuals with acute myeloid leukemia (AML) are at risk for significant physical and psychological burden related to their illness. While overall survival rates are improving, treatments may be associated with lengthy hospitalizations ... Full text Cite

Oral Adherence in Adults with Acute Myeloid Leukemia: Results of a Mixed Methods Study

Conference Blood · November 13, 2019 BACKGROUND: The incidence of AML is increasing, in part due to the overall aging population; median age at presentation is 67 years. Overall 5-year survival rates are as low as 5%-10% in adults >60 years (Wang, 2014). While standard treatment fo ... Full text Cite

Oral adherence in adults with acute myeloid leukemia (AML): Results of a mixed methods study.

Conference Journal of Clinical Oncology · November 1, 2019 105 Background: The incidence of AML is increasing, in part due to an aging population. Amid established intravenous (IV) or subcutaneous chemotherapies , recent drug approvals have ushered in an era of oral medication (OM) appro ... Full text Cite

Psychosocial Experiences of Young Adults Diagnosed With Acute Leukemia During Hospitalization for Induction Chemotherapy Treatment.

Journal Article Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · April 2019 The diagnosis of cancer for anyone is a time of fear and uncertainty. For young adults (YAs) diagnosed with acute leukemia (AL), there are the additional challenges related to lengthy aggressive in-hospital treatment, multiple concurrent symptoms, and decr ... Full text Cite

Emerging Models of Providing Oncology Palliative Care.

Journal Article Seminars in oncology nursing · August 2018 ObjectiveTo describe palliative care integration into oncology, including several models that facilitate this integration, important considerations when initiating a program, special oncologic populations that would benefit from palliative care, a ... Full text Cite

Symptom Management and Psychosocial Needs of Adults With Acute Myeloid Leukemia During Induction Treatment: A Pilot Study.

Journal Article Cancer nursing · November 2017 BackgroundPatients with a new diagnosis of acute myeloid leukemia (AML) are at risk of experiencing a high symptom burden due to the disease and its treatment, which includes a long period of hospitalization.ObjectiveThe aim of this pilot ... Full text Cite

Social Media: Support for Survivors and Young Adults With Cancer

Journal Article Clinical journal of oncology nursing · October 2017 Social media use is ubiquitous among young adults. Young adults with cancer must make important decisions about where, what, and how to share information on social media. Oncology nurses are in a unique position to start conversations about the risks and b ... Full text Cite

Characteristics of palliative care consultation at an academic level one trauma center.

Journal Article American journal of surgery · October 2017 BackgroundThe current status of palliative care consultation for trauma patients has not been well characterized. We hypothesized that palliative care consultation currently is requested for patients too late to have any clinical significance. ... Full text Cite

Progressive Assessment and Competency Evaluation Framework for Integrating Simulation in Nurse Practitioner Education.

Journal Article The journal for nurse practitioners : JNP · July 2017 Competencies for nurse practitioner students have been published with the goal of preparing graduates who are ready to meet the challenges of an increasingly complex health care system. Standardized preclinical assessment of graduate-level competencies hav ... Full text Cite

The association between the gut microbiome and fatigue in individuals living with cancer: a systematic review.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · April 2024 PurposeFatigue is the most distressing symptom for individuals with cancer. While numerous studies have investigated biological pathways that could underlie the mechanism of fatigue, the cause of fatigue remains unclear. This review aimed to inves ... Full text Cite

"I don't have a choice but to keep getting up and doing the things that protect her": The informal caregiver's adaptation to the cancer diagnosis.

Journal Article Journal of psychosocial oncology · February 2024 PurposePatients with hematologic malignancies (HM) typically rely on informal caregivers for support. Caregivers experience distress, poorer health, and lower quality of life. This study aimed to understand caregivers' experiences adapting to, and ... Full text Cite

Crossroads of parental decision making: Intersections of hope, communication, relationships, and emotions.

Journal Article Journal of child health care : for professionals working with children in the hospital and community · June 2023 Parents of children born with complex life-threatening chronic conditions (CLTCs) experience an uncertain trajectory that requires critical decision making. Along this trajectory, hope plays an influential but largely unexplored role; therefore, this quali ... Full text Cite

THE IMPORTANCE OF ENGAGING CLINIC NURSES IN NURSING RESEARCH

Conference ONCOLOGY NURSING FORUM · 2023 Cite

How Caregivers Cope and Adapt When a Family Member Is Diagnosed With a Hematologic Malignancy: Informing Supportive Care Needs.

Journal Article Cancer nursing · November 2022 BackgroundInformal family caregivers (FCs) of adults with various diseases including hematologic malignancy (HM) experience low quality of life and psychological well-being. Although HMs are life-threatening cancers associated with high mortality, ... Full text Cite

Impact of a Hematologic Malignancy Diagnosis and Treatment on Patients and Their Family Caregivers.

Journal Article Oncology nursing forum · August 2022 ObjectivesHematologic malignancies (HMs) are life-threatening cancers that frequently entail aggressive, long, inpatient treatment protocols. This can result in numerous concurrent symptoms and decreased quality of life for patients and can affect ... Full text Cite

The relationship between emotional well-being and understanding of prognosis in patients with acute myeloid leukemia (AML).

Journal Article Support Care Cancer · January 2022 PURPOSE: Adults with acute myeloid leukemia (AML) face considerable distress and often have a poor prognosis. However, little is known about these patients' perceptions of prognosis and how this relates to emotional well-being (EWB). METHODS: We conducted ... Full text Link to item Cite

Oral adherence in adults with acute myeloid leukemia (AML): results of a mixed methods study.

Journal Article Support Care Cancer · November 2020 INTRODUCTION: The incidence of AML is increasing, in part due to an aging population. Since 2017, eight novel agents have been introduced, 6 of which are oral: midostaurin, enasidenib, ivosidenib, gilteritinib, glasdegib, and venetoclax. With an increase i ... Full text Link to item Cite

Psychological and Financial Distress Management in Adults With Acute Leukemia.

Journal Article Seminars in oncology nursing · December 2019 ObjectivesTo review and summarize psychological and financial distress in adults with acute leukemia and provide evidence-based methods that nurses can apply to alleviate distress experienced by patients.Data sourcesOncology and palliativ ... Full text Cite

Cancer-Related Distress and Unmet Needs Among Acute Myeloid Leukemia Survivors

Conference Blood · November 13, 2019 Background: Individuals with acute myeloid leukemia (AML) are at risk for significant physical and psychological burden related to their illness. While overall survival rates are improving, treatments may be associated with lengthy hospitalizations ... Full text Cite

Oral Adherence in Adults with Acute Myeloid Leukemia: Results of a Mixed Methods Study

Conference Blood · November 13, 2019 BACKGROUND: The incidence of AML is increasing, in part due to the overall aging population; median age at presentation is 67 years. Overall 5-year survival rates are as low as 5%-10% in adults >60 years (Wang, 2014). While standard treatment fo ... Full text Cite

Oral adherence in adults with acute myeloid leukemia (AML): Results of a mixed methods study.

Conference Journal of Clinical Oncology · November 1, 2019 105 Background: The incidence of AML is increasing, in part due to an aging population. Amid established intravenous (IV) or subcutaneous chemotherapies , recent drug approvals have ushered in an era of oral medication (OM) appro ... Full text Cite

Psychosocial Experiences of Young Adults Diagnosed With Acute Leukemia During Hospitalization for Induction Chemotherapy Treatment.

Journal Article Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · April 2019 The diagnosis of cancer for anyone is a time of fear and uncertainty. For young adults (YAs) diagnosed with acute leukemia (AL), there are the additional challenges related to lengthy aggressive in-hospital treatment, multiple concurrent symptoms, and decr ... Full text Cite

Emerging Models of Providing Oncology Palliative Care.

Journal Article Seminars in oncology nursing · August 2018 ObjectiveTo describe palliative care integration into oncology, including several models that facilitate this integration, important considerations when initiating a program, special oncologic populations that would benefit from palliative care, a ... Full text Cite

Symptom Management and Psychosocial Needs of Adults With Acute Myeloid Leukemia During Induction Treatment: A Pilot Study.

Journal Article Cancer nursing · November 2017 BackgroundPatients with a new diagnosis of acute myeloid leukemia (AML) are at risk of experiencing a high symptom burden due to the disease and its treatment, which includes a long period of hospitalization.ObjectiveThe aim of this pilot ... Full text Cite

Social Media: Support for Survivors and Young Adults With Cancer

Journal Article Clinical journal of oncology nursing · October 2017 Social media use is ubiquitous among young adults. Young adults with cancer must make important decisions about where, what, and how to share information on social media. Oncology nurses are in a unique position to start conversations about the risks and b ... Full text Cite

Characteristics of palliative care consultation at an academic level one trauma center.

Journal Article American journal of surgery · October 2017 BackgroundThe current status of palliative care consultation for trauma patients has not been well characterized. We hypothesized that palliative care consultation currently is requested for patients too late to have any clinical significance. ... Full text Cite

Progressive Assessment and Competency Evaluation Framework for Integrating Simulation in Nurse Practitioner Education.

Journal Article The journal for nurse practitioners : JNP · July 2017 Competencies for nurse practitioner students have been published with the goal of preparing graduates who are ready to meet the challenges of an increasingly complex health care system. Standardized preclinical assessment of graduate-level competencies hav ... Full text Cite

Perceived economic hardship and distress in acute myelogenous leukemia

Journal Article Journal of Oncology Navigation and Survivorship · 2017 Multiple studies have quantified the direct and indirect costs and related patient hardship and distress in general cancer care; however, little attention has been focused on a particular cancer with great potential for economic hardship, acute myeloid leu ... Cite

The unique supportive care needs of a mother with acute myeloid leukemia during treatment.

Journal Article Clinical journal of oncology nursing · February 2015 Acute myeloid leukemia (AML) is an aggressive cancer of the blood that is linked with poor survival. The disease requires immediate intensive chemotherapy treatment that leaves patients hospitalized for at least one month and often longer, depending on the ... Full text Cite

Management of febrile neutropenia in a patient with acute leukemia.

Journal Article Journal of emergency nursing · July 2014 Full text Cite

Distress in patients with acute leukemia: a concept analysis.

Journal Article Cancer nursing · May 2014 BackgroundPatients with acute leukemia (AL) require immediate and aggressive inpatient treatment that results in many weeks to months of hospitalization. Thus, it is not surprising that distress has been found in as many as 45.5% of patients. Alth ... Full text Cite

Physiologic and psychological symptoms experienced by adults with acute leukemia: an integrative literature review.

Journal Article Oncology nursing forum · May 2014 Purpose/objectivesTo evaluate the current knowledge of symptoms experienced by adults with acute leukemia (AL) and provide evidence to inform practice and research.Data sourcesLiterature review using an electronic search supplemented by a ... Full text Cite

No stone left unturned: challenges encountered during recruitment of women with advanced ovarian cancer for a phase I study.

Journal Article Applied nursing research : ANR · November 2013 The recruitment and accrual of participants for cancer clinical trial research is often challenging. Chronic low accrual rates negatively influence the findings and generalizability that can be drawn from the available pool of research. There is a need for ... Full text Cite

Young women's experiences with complementary therapies during cancer described through illness blogs.

Journal Article Western journal of nursing research · November 2013 Many young women with cancer have a high symptom burden and negative psychosocial consequences as a result of their disease. To offset some of these experiences, a growing number of young women with cancer are writing about their experience with complement ... Full text Cite

Striving to improve patient-reported outcomes for cancer survivors as the war wages on.

Journal Article Annals of oncology : official journal of the European Society for Medical Oncology · September 2013 Full text Cite

A complementary care study combining flaxseed oil, caffeine, fasting, and exercise in women diagnosed with advanced ovarian cancer: findings from a case study.

Journal Article Holistic nursing practice · November 2012 This article presents the experiences of 1 participant with advanced ovarian cancer enrolled in a proof of concept complementary therapy study evaluating the effects of a combined intervention of flaxseed oil, fasting, caffeine, and exercise. Improvements ... Full text Cite

Management of Cancer Related Distress in Patients with a Hematological Malignancy.

Journal Article Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · October 2012 Patients with hematologic malignancies often require urgent, aggressive, and lengthy chemotherapy treatment. These treatment regimens, divided into cycles, result in extended, often isolating periods of hospitalization where any direct clinical benefit for ... Full text Cite

Physical activity in patients with advanced-stage cancer: a systematic review of the literature.

Journal Article Clinical journal of oncology nursing · June 2012 The importance of physical activity for chronic disease prevention and management has become generally well accepted. The number of research interventions and publications examining the benefits of physical activity for patients with cancer has been rising ... Full text Cite

Promoting evidence-based management of anemia in cancer patients: concurrent and discriminant validity of RESPOND, a web-based clinical guidance system based on the EORTC guidelines for supportive care in cancer.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · July 2010 Goal of workThe goal of this study is to test the validity of RESPOND, a web-based decision support system to assess and manage anemia in cancer patients as per the European Organisation for Research and Treatment of Cancer (EORTC) guidelines. The ... Full text Cite

Modeling of treatment response to erythropoiesis-stimulating agents as a function of center- and patient-related variables: results from the Anemia Cancer Treatment (ACT) study.

Journal Article Annals of oncology : official journal of the European Society for Medical Oncology · October 2009 BackgroundIn anemic cancer patients treated with erythropoiesis-stimulating agent (ESA), (i) to examine the proportion of variance in hemoglobin (Hb) outcomes attributable to patients versus center, country, and region and (ii) to develop predicti ... Full text Cite

Treatment patterns and outcomes in the management of anaemia in cancer patients in Europe: findings from the Anaemia Cancer Treatment (ACT) study.

Journal Article European journal of cancer (Oxford, England : 1990) · June 2009 ObjectivesTo examine anaemia management in cancer patients treated with erythropoiesis-stimulating agents (ESAs) in Europe.MethodsRetrospective pharmacoepidemiologic study of 2192 patients from 307 centres. Minimum of 3 visits over 8-10 w ... Full text Cite

Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study.

Journal Article Blood · May 2009 Imatinib mesylate (imatinib) has been shown to be highly efficacious in the treatment of chronic myeloid leukemia (CML). Continuous and adequate dosing is essential for optimal outcomes and with imatinib treatment possibly being lifelong, patient adherence ... Full text Cite

Managing cancer-related anaemia in congruence with the EORTC guidelines is an independent predictor of haemoglobin outcome: initial evidence from the RESPOND study.

Journal Article European journal of cancer (Oxford, England : 1990) · January 2009 PurposeTo model the relationship between scores for practicing in congruence (CSs; 0-10) with EORTC guidelines for erythropoietic proteins (EPs) and haemoglobin (Hb) outcomes observed in the validation study of the RESPOND system.MethodsT ... Full text Cite