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Tomokazu Souma

Associate Professor in Medicine
Medicine, Nephrology

Current Appointments & Affiliations


Associate Professor in Medicine · 2024 - Present Medicine, Nephrology, Medicine
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

In the News


Published November 15, 2022
Protected From a Form of Cell Death, Women are More Resilient to Kidney Disease

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Recent Publications


Ferroptosis and Its Survivors in Kidney Injury and Repair.

Journal Article J Am Soc Nephrol · December 23, 2025 Ferroptosis is a distinct necrotic form of regulated cell death caused by a breakdown in membrane redox homeostasis. Accumulating evidence highlights a central role for ferroptosis in both acute and chronic kidney diseases, with proximal tubule cells being ... Full text Link to item Cite

Altered renal vascular patterning reduces ischemic kidney injury and limits age-associated vascular loss.

Journal Article Am J Physiol Renal Physiol · June 1, 2025 The kidney vasculature has a complex arrangement, which runs in both series and parallel to perfuse the renal tissue and appropriately filter plasma. Recent studies have demonstrated that the development of this vascular pattern is dependent on netrin-1 se ... Full text Link to item Cite

Pax inhibition: stressing proximal tubule for successful repair.

Journal Article Am J Physiol Renal Physiol · February 1, 2025 Full text Link to item Cite
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Recent Grants


Molecular control of a novel transitional cell state in alveolar regeneration

ResearchInvestigator · Awarded by National Institutes of Health · 2020 - 2029

Identification of Host-Specific Determinants of APOL1-associated COVAN

ResearchCo-Mentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029

U2C/TL1 NC KUH TRIO Administrative Core

ResearchPreceptor · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028

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Education, Training & Certifications


Tohoku University (Japan) · 2012 Ph.D.
Shimane University (Japan) · 2004 M.D.