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Tomokazu Souma

Associate Professor in Medicine
Medicine, Nephrology

Current Appointments & Affiliations


Associate Professor in Medicine · 2024 - Present Medicine, Nephrology, Medicine
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

In the News


Published November 15, 2022
Protected From a Form of Cell Death, Women are More Resilient to Kidney Disease

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Recent Publications


Pax inhibition: stressing proximal tubule for successful repair.

Journal Article Am J Physiol Renal Physiol · February 1, 2025 Full text Link to item Cite

Targeting allograft inflammatory factor 1 reprograms kidney macrophages to enhance repair.

Journal Article J Clin Invest · January 21, 2025 The role of macrophages (MΦs) remains incompletely understood in kidney injury and repair. The plasticity of MΦs offers an opportunity to polarize them toward mediating injury resolution in both native and transplanted kidneys undergoing ischemia and/or re ... Full text Link to item Cite

Intestinal Cyp24a1 regulates vitamin D locally independent of systemic regulation by renal Cyp24a1 in mice.

Journal Article J Clin Invest · December 17, 2024 Vitamin D regulates mineral homeostasis. The most biologically active form of vitamin D, 1,25-dihydroxyvitamin D (1,25D), is synthesized by CYP27B1 from 25-dihydroxyvitamin D (25D) and is inactivated by CYP24A1. Human monogenic diseases and genome-wide ass ... Full text Link to item Cite
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Recent Grants


Identification of Host-Specific Determinants of APOL1-associated COVAN

ResearchCo-Mentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029

U2C/TL1 NC KUH TRIO Administrative Core

ResearchPreceptor · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028

TRIO NRSA Training Core-Pre Doc Trainee

Inst. Training Prgm or CMEPreceptor · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028

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Education, Training & Certifications


Tohoku University (Japan) · 2012 Ph.D.
Shimane University (Japan) · 2004 M.D.