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Trey Carlton Mullikin

Assistant Professor of Radiation Oncology
Radiation Oncology

Current Appointments & Affiliations


Assistant Professor of Radiation Oncology · 2024 - Present Radiation Oncology, Clinical Science Departments
Member of the Duke Cancer Institute · 2022 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published July 10, 2025
How Duke is Transforming Care for Brain and Spine Metastasis

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Recent Publications


Knowledge-based deep residual U-Net (DRU) for synthetic CT generation using a single MR volume for frameless radiosurgery.

Journal Article J Appl Clin Med Phys · January 2026 PURPOSE: To develop a knowledge-based deep model for sCT generation from a single MR volume in LINAC-based frameless SRS, enabling the MR-only workflow without extra CT simulation. METHODS: A total of 139 patients were included in the study, with 120 used ... Full text Link to item Cite

Neurocognitive outcomes in patients with brain metastases: a systematic review.

Journal Article Lancet Oncol · December 2025 Multimodality therapy, including surgery, radiotherapy, and systemic therapy, has significantly improved overall survival for patients with brain metastases. However, treatment-related neurocognitive sequelae remain a major challenge in survivorship. Altho ... Full text Link to item Cite

Management outcomes for biopsy-proven radiation necrosis in patients with brain metastases in the era of immune-checkpoint blockade.

Journal Article J Neurooncol · October 2025 PURPOSE: Immunotherapy and stereotactic radiosurgery (SRS) are frequently combined in the management of brain metastases from non-small cell lung cancer (NSCLC) and melanoma. However, concurrent SRS and dual immune-checkpoint inhibition (ICPI) elevate the ... Full text Open Access Link to item Cite
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Education, Training & Certifications


Mayo Clinic, Alix School of Medicine · 2016 M.D.