Recent Publications
JAK-STAT activation contributes to cytotoxic T cell-mediated basal cell death in human chronic lung allograft dysfunction.
Journal Article JCI Insight · March 22, 2023 Chronic lung allograft dysfunction (CLAD) is the leading cause of death in lung transplant recipients. CLAD is characterized clinically by a persistent decline in pulmonary function and histologically by the development of airway-centered fibrosis known as ... Full text Link to item CiteABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain.
Journal Article Cell Rep · August 30, 2022 Patients with human epidermal growth factor receptor 2-positive (HER2+/ERBB2) breast cancer often present with brain metastasis. HER2-targeted therapies have not been successful to treat brain metastases in part due to poor blood-brain barrier (BBB) penetr ... Full text Link to item CiteABL kinase inhibition sensitizes primary lung adenocarcinomas to chemotherapy by promoting tumor cell differentiation.
Journal Article Oncotarget · March 8, 2019 Lung cancer is the leading cause of cancer mortality in the United States, with an overall five-year survival rate of ~16%. Non-small cell lung cancer (NSCLC) accounts for ~80% of all lung cancer cases, and the majority (40%) of these are adenocarcinomas. ... Full text Link to item CiteRecent Grants
Regulation of cell permeability by Abl kinases and implications for the treating of acute lung injury
FellowshipPI-Fellow · Awarded by National Institutes of Health · 2015 - 2018Targeting Integrator Kinases in Lung Cancer Metastasis
ResearchGraduate Student · Awarded by Free to Breathe · 2015 - 2018Role of Abl Kinases in immune cell signaling
ResearchGraduate Student · Awarded by National Institutes of Health · 2004 - 2017View All Grants