Recent Publications
A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death.
Journal Article J Vis Exp · June 6, 2025 The number of advanced heart failure patients who can receive a heart transplant is limited by a shortage of suitable organ donors. In efforts to expand the donor pool, alternative donation and procurement methods have been developed, including heart trans ... Full text Link to item CiteEarly U.S. Heart Transplant Experience With Normothermic Regional Perfusion Following Donation After Circulatory Death.
Journal Article JACC Heart Fail · December 2024 BACKGROUND: Heart transplantation following donation after circulatory death (DCD HT) has short-term survival outcomes comparable to donation after brain death and has led to a significant increase in transplantation volume. The U.S. experience with the no ... Full text Link to item CiteCapsid-mediated control of adeno-associated viral transcription determines host range.
Journal Article Cell Rep · March 26, 2024 Adeno-associated virus (AAV) is a member of the genus Dependoparvovirus, which infects a wide range of vertebrate species. Here, we observe that, unlike most primate AAV isolates, avian AAV is transcriptionally silenced in human cells. By swapping the VP1 ... Full text Link to item CiteRecent Grants
Evaluation of adeno-associated viral (AAV) mediated gene replacement therapy as a therapeutic option for SLC25A4 deficiency
FellowshipPI-Fellow · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2025View All Grants