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Research Interests

My primary research interest is (and has been for a number of years) developmental neuroscience—I find fascinating the orchestration of cell divisions, fate decisions, and transcriptional/translational programming in order to form arguably the most complex and least understood organ. In the Silver lab, I’ll be investigating how missense mutations in the X-linked RNA helicase DDX3X affect radial glial biology in an effort to better understand DDX3X syndrome, a recently characterized neurodevelopmental disorder that accounts for 1-3% of female intellectual disability.