Current Duke Appointments & Affiliations
Assistant Research Professor in the Department of Biomedical Engineering
·
2026 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Scholarly Works
RYR1+ skeletal muscle-derived extracellular vesicles are exercise responsive and associated with insulin action.
Journal article J Transl Med · May 26, 2026 BACKGROUND: Skeletal muscle is a central regulator of insulin sensitivity and glucose homeostasis. The ryanodine receptor 1 (RYR1) is highly expressed in skeletal muscle and plays a key role in myogenic differentiation. We hypothesize that RYR1+ extracellu ... Full text Link to item CiteDevelopment and modeling of cardiac autonomic innervation.
Journal article Nature cardiovascular research · December 2025 Autonomic innervation is important for heart development and function, as well as for the response to injury and hemodynamic stress. However, the mechanisms underlying neurocardiac interactions are difficult to investigate in vivo, prompting the need for a ... Full text CiteHuman Myobundle Platform for Studying the Role of Notch Signaling in Satellite Cell Phenotype and Function.
Journal article Advanced healthcare materials · May 2025 Notch signaling plays a pivotal role in regulating satellite cell (SC) behavior during skeletal muscle development, homeostasis, and repair. While well-characterized in mouse models, the impact of Notch signaling in human muscle tissues remains largely und ... Full text CiteRecent Grants
Engineering a Human Skeletal Muscle Tissue Model of LGMD2B
ResearchCo Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028Development of 3-dimensional Human Skeletal Muscle Tissue Models of Limb-Girdle Muscular Dystrophy Type 2B
ResearchCo Investigator · Awarded by Jain Foundation · 2017 - 2026Microphysiological Human Tissue Systems for Monitoring of Genome Editing Outcomes
ResearchResearch Scientist · Awarded by National Institutes of Health · 2019 - 2024View All Grants
Education
University of Dundee (United Kingdom) ·
2011
Ph.D.