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Alastair Khodabukus

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering

Current Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2026 - Present Biomedical Engineering, Pratt School of Engineering

Recent Publications


Development and modeling of cardiac autonomic innervation.

Journal Article Nature cardiovascular research · December 2025 Autonomic innervation is important for heart development and function, as well as for the response to injury and hemodynamic stress. However, the mechanisms underlying neurocardiac interactions are difficult to investigate in vivo, prompting the need for a ... Full text Cite

Human Myobundle Platform for Studying the Role of Notch Signaling in Satellite Cell Phenotype and Function.

Journal Article Advanced healthcare materials · May 2025 Notch signaling plays a pivotal role in regulating satellite cell (SC) behavior during skeletal muscle development, homeostasis, and repair. While well-characterized in mouse models, the impact of Notch signaling in human muscle tissues remains largely und ... Full text Cite

Engineered myovascular tissues for studies of endothelial/satellite cell interactions.

Journal Article Acta biomaterialia · October 2024 In native skeletal muscle, capillaries reside in close proximity to muscle stem cells (satellite cells, SCs) and regulate SC numbers and quiescence through partially understood mechanisms that are difficult to study in vivo. This challenge could be address ... Full text Cite
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Recent Grants


Engineering Heterocellular Human Skeletal Muscle Tissues to Recreate and Study Native Stem Cell Niche Function

ResearchResearch Scientist · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2024 - 2029

Engineering a Human Skeletal Muscle Tissue Model of LGMD2B

ResearchCo Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028

Development of 3-dimensional Human Skeletal Muscle Tissue Models of Limb-Girdle Muscular Dystrophy Type 2B

ResearchCo Investigator · Awarded by Jain Foundation · 2017 - 2026

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Education, Training & Certifications


University of Dundee (United Kingdom) · 2011 Ph.D.