Scholars@Duke
Aimee Byonghee Chung

Aimee Byonghee Chung

Associate Professor of Pediatrics
Pediatrics, Medicine/Pediatrics
3116 N Duke Street, Durham, NC 27704
3116 N Duke Street, Durham, NC 27704
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Selected Publications

Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells.

Journal Article Mol Cancer Ther · November 2001 O6-Benzylguanine (BG) inactivates O6-alkylguanine-DNA alkyltransferase (AGT), resulting in an increase in the sensitivity of cells to the toxic effects of O6-alkylating agents. BG significantly enhances the cytotoxicity and decreases the mutagenicity of ni ... Link to item Cite