Aimee Kirsch Zaas
Professor of Medicine
Medical education
Genomic applications for diagnosis of infectious diseases
Genomic applications for prediction of infectious diseases
Genomic applications for diagnosis of infectious diseases
Genomic applications for prediction of infectious diseases
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Infectious Diseases, Medicine 2020
Contact Information
- 2301 Erwin Rd, Box 3182, Durham, NC 27710
- Duke Box 3182, DUMC, Durham, NC 27710
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aimee.zaas@duke.edu
(919) 681-1464
- Background
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Education, Training, & Certifications
- Fellow in Infectious Diseases, Medicine, Duke University 2003 - 2004
- Fellow in Infectious Diseases, Medicine, Duke University 2001 - 2002
- Medical Resident, Medicine, Johns Hopkins University 1998 - 2001
- M.D., Northwestern University 1998
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2015 - 2020
- Assistant Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2010 - 2019
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2015
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2005 - 2010
- Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2004 - 2005
- Instructor, Temporary in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2004
- Recognition
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In the News
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MAY 24, 2023 School of Medicine -
SEP 19, 2013 CBS News
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- Research
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Selected Grants
- Duke Civility Champions awarded by Josiah Macy, Jr. Foundation 2023 - 2024
- Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG) awarded by National Institutes of Health 2018 - 2023
- Acute Lower Respirator Tract with Lung Ultrasound awarded by Thrasher Research Fund 2018 - 2020
- Bridging the Treatment Gap: Improving Time to Cure of Hepatitis C in North Carolina awarded by American College of Physicians 2018 - 2019
- Learning Health System Research Champion Award awarded by Association of American Medical Colleges 2015 - 2017
- Mid-Career Investigator Award: Preventing and Diagnosing Fungal Disease in Transplantation awarded by National Institutes of Health 2007 - 2013
- Genetic Determinants of A. Fumigatus Susceptibility awarded by National Institutes of Health 2005 - 2009
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External Relationships
- Up To Date Inc/Wolters Kluwer Health
- UpToDate, Inc
- Weill Cornell Medical College-Qatar
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Martin, Shannon K., Kathleen M. Finn, Michael Kisielewski, Rachel Simmons, and Aimee K. Zaas. “Residency Program Responses to Early COVID-19 Surges Highlight Tension as to Whether Residents Are Learners or Essential Workers.” Acad Med 97, no. 11 (November 1, 2022): 1683–90. https://doi.org/10.1097/ACM.0000000000004800.Full Text Link to Item
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Windish, Donna M., Jillian S. Catalanotti, Aimee Zaas, Michael Kisielewski, and John P. Moriarty. “Training in Safe Opioid Prescribing and Treatment of Opioid Use Disorder in Internal Medicine Residencies: a National Survey of Program Directors.” J Gen Intern Med 37, no. 11 (August 2022): 2650–60. https://doi.org/10.1007/s11606-021-07102-y.Full Text Link to Item
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Holcomb, Zachary E., Julie M. Steinbrink, Aimee K. Zaas, Marisol Betancourt, Jennifer L. Tenor, Dena L. Toffaletti, J Andrew Alspaugh, John R. Perfect, and Micah T. McClain. “Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii.” J Fungi (Basel) 8, no. 5 (April 22, 2022). https://doi.org/10.3390/jof8050430.Full Text Link to Item
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Finn, Kathleen M., Alec B. O’Connor, Kelly McGarry, Linda Harris, and Aimee Zaas. “Prevalence and Sources of Mistreatment Experienced by Internal Medicine Residents.” Jama Intern Med 182, no. 4 (April 1, 2022): 448–50. https://doi.org/10.1001/jamainternmed.2022.0051.Full Text Link to Item
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O’Connor, Alec B., Jillian S. Catalanotti, Sanjay V. Desai, MaryGrace Zetkulic, Michael Kisielewski, Lisa L. Willett, and Aimee K. Zaas. “Internal Medicine Residency Program Director Support and Burnout During the COVID-19 Pandemic: Results of a National Survey.” Journal of Graduate Medical Education 14, no. 2 (April 2022): 218–23. https://doi.org/10.4300/jgme-d-21-00804.1.Full Text
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Simmons, Rachel P., Jordan Ortiz, Michael Kisielewski, Aimee Zaas, and Kathleen M. Finn. “Virtual Recruitment: Experiences and Perspectives of Internal Medicine Program Directors.” Am J Med 135, no. 2 (February 2022): 258-263.e1. https://doi.org/10.1016/j.amjmed.2021.10.017.Full Text Link to Item
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Harris, Rachel, Kyle Covington, Cristin Colford, Nancy Denizard-Thompson, Michael Contarino, Kimberley Evans, Aimee Zaas, M Suzanne Kraemer, and Diana McNeill. “Focusing on Diversity: A Regional Internal Medicine Residency Viewpoint on Underrepresented Minority Support, Retention, and Mentoring.” J Grad Med Educ 13, no. 2 (April 2021): 181–88. https://doi.org/10.4300/JGME-D-20-00729.1.Full Text Link to Item
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Finn, Kathleen M., Andrew J. Halvorsen, Saima Chaudhry, Sanjay Desai, Denise Dupras, Shalini Reddy, Sandhya Wahi-Gururaj, Lisa Willett, and Aimee K. Zaas. “Does Increased Schedule Flexibility Lead to Change? A National Survey of Program Directors on 2017 Work Hours Requirements.” J Gen Intern Med 35, no. 11 (November 2020): 3205–9. https://doi.org/10.1007/s11606-020-06109-1.Full Text Link to Item
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Steinbrink, Julie M., Aimee K. Zaas, Marisol Betancourt, Jennifer L. Modliszewski, David L. Corcoran, and Micah T. McClain. “A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states.” Transl Res 219 (May 2020): 1–12. https://doi.org/10.1016/j.trsl.2020.02.005.Full Text Link to Item
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Finn, Kathleen M., Aimee K. Zaas, Furman S. McDonald, Michael Melfe, Michael Kisielewski, and Lisa L. Willett. “Misinterpretation of the American Board of Internal Medicine Leave Policies for Resident Physicians Around Parental Leave.” Ann Intern Med 172, no. 8 (April 21, 2020): 570–72. https://doi.org/10.7326/M19-2490.Full Text Link to Item
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Nimmagadda, Sai N., Firas S. Midani, Heather Durand, Aspen T. Reese, Caitlin C. Murdoch, Bradley P. Nicholson, Timothy Veldman, et al. “Nasal microbiota exhibit neither reproducible nor orderly dynamics following rhinoviral infection,” April 17, 2020. https://doi.org/10.1101/2020.04.11.20061911.Full Text
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Ryskina, Kira L., Cynthia D. Smith, Vineet M. Arora, Aimee K. Zaas, Andrew J. Halvorsen, Arlene Weissman, and Sandhya Wahi-Gururaj. “Relationship Between Institutional Investment in High-Value Care (HVC) Performance Improvement and Internal Medicine Residents' Perceptions of HVC Training.” Acad Med 93, no. 10 (October 2018): 1517–23. https://doi.org/10.1097/ACM.0000000000002257.Full Text Link to Item
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Vidyarthi, Arpana R., Gurpreet Dhaliwal, Bradley Monash, Koin Lon Shum, Joanne Lee, and Aimee K. Zaas. “Hot in the Tropics.” J Hosp Med 12, no. 6 (June 2017): 462–66. https://doi.org/10.12788/jhm.2753.Full Text Link to Item
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Boggan, Joel C., Aparna Swaminathan, Samantha Thomas, David L. Simel, Aimee K. Zaas, and Jonathan G. Bae. “Improving Timely Resident Follow-Up and Communication of Results in Ambulatory Clinics Utilizing a Web-Based Audit and Feedback Module.” J Grad Med Educ 9, no. 2 (April 2017): 195–200. https://doi.org/10.4300/JGME-D-16-00460.1.Full Text Open Access Copy Link to Item
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Campbell, Elizabeth A., Matthew J. Crowley, Benjamin J. Powers, Linda L. Sanders, Maren K. Olsen, Susanne Danus, Diana B. McNeill, and Aimee K. Zaas. “Diabetes Quality of Care Before and After Implementation of a Resident Clinic Practice Partnership System.” Am J Med Qual 32, no. 1 (2017): 66–72. https://doi.org/10.1177/1062860615615210.Full Text Link to Item
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Elmariah, Hany, Samantha Thomas, Joel C. Boggan, Aimee Zaas, and Jonathan Bae. “The Burden of Burnout.” Am J Med Qual 32, no. 2 (2017): 156–62. https://doi.org/10.1177/1062860615625802.Full Text Open Access Copy Link to Item
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Meade, Lauren B., Kathleen Heist Suddarth, Ronald R. Jones, Aimee K. Zaas, Terry Albanese, Kenji Yamazaki, and Cheryl W. O’Malley. “Patients, Nurses, and Physicians Working Together to Develop a Discharge Entrustable Professional Activity Assessment Tool.” Acad Med 91, no. 10 (October 2016): 1388–91. https://doi.org/10.1097/ACM.0000000000001189.Full Text Link to Item
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Willett, Lisa L., Andrew J. Halvorsen, Michael Adams, Karen M. Chacko, Saima Chaudhry, Furman S. McDonald, Amy S. Oxentenko, Sara L. Swenson, Aimee Zaas, and Vineet M. Arora. “Factors Associated with Declining Residency Program Pass Rates on the ABIM Certification Examination.” Am J Med 129, no. 7 (July 2016): 759–65. https://doi.org/10.1016/j.amjmed.2016.03.020.Full Text Link to Item
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Dotters-Katz, Sarah, Charles W. Hargett, Aimee K. Zaas, and Lisa G. Criscione-Schreiber. “What motivates residents to teach? The Attitudes in Clinical Teaching study.” Med Educ 50, no. 7 (July 2016): 768–77. https://doi.org/10.1111/medu.13075.Full Text Link to Item
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Suddarth, Kathleen Heist, Ronald R. Jones, Cheryl W. O’Malley, David Paje, Kenji Yamazaki, Aimee K. Zaas, and Lauren B. Meade. “Implementation of Milestones-Based Assessment for a Safe and Effective Discharge.” Am J Med 129, no. 6 (June 2016): 640–46. https://doi.org/10.1016/j.amjmed.2016.02.005.Full Text Link to Item
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Broderick-Forsgren, Kathleen, Wynn G. Hunter, Ryan D. Schulteis, Wen-Wei Liu, Joel C. Boggan, Poonam Sharma, Steven Thomas, Aimee Zaas, and Jonathan Bae. “Doctor Who? A Quality Improvement Project to Assess and Improve Patients' Knowledge of Their Inpatient Physicians.” J Grad Med Educ 8, no. 2 (May 2016): 197–201. https://doi.org/10.4300/JGME-D-15-00067.1.Full Text Open Access Copy Link to Item
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Husain, Shahid, Amparo Sole, Barbara D. Alexander, Saima Aslam, Robin Avery, Christian Benden, Eliane M. Billaud, et al. “The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary.” J Heart Lung Transplant 35, no. 3 (March 2016): 261–82. https://doi.org/10.1016/j.healun.2016.01.007.Full Text Link to Item
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Liu, Tzu-Yu, Thomas Burke, Lawrence P. Park, Christopher W. Woods, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “An individualized predictor of health and disease using paired reference and target samples.” Bmc Bioinformatics 17 (January 22, 2016): 47. https://doi.org/10.1186/s12859-016-0889-9.Full Text Link to Item
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Tsalik, Ephraim L., Ricardo Henao, Marshall Nichols, Thomas Burke, Emily R. Ko, Micah T. McClain, Lori L. Hudson, et al. “Host gene expression classifiers diagnose acute respiratory illness etiology.” Sci Transl Med 8, no. 322 (January 20, 2016): 322ra11. https://doi.org/10.1126/scitranslmed.aad6873.Full Text Open Access Copy Link to Item
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McClain, Micah T., Bradly P. Nicholson, Lawrence P. Park, Tzu-Yu Liu, Alfred O. Hero, Ephraim L. Tsalik, Aimee K. Zaas, et al. “A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses.” Open Forum Infect Dis 3, no. 1 (January 2016): ofw007. https://doi.org/10.1093/ofid/ofw007.Full Text Open Access Copy Link to Item
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Wysham, Nicholas G., Lynn Howie, Krish Patel, C Blake Cameron, Gregory P. Samsa, Laura Roe, Amy P. Abernethy, and Aimee Zaas. “Development and Refinement of a Learning Health Systems Training Program.” Egems (Wash Dc) 4, no. 1 (2016): 1236. https://doi.org/10.13063/2327-9214.1236.Full Text Open Access Copy Link to Item
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Tsalik, Ephraim L., Micah McClain, and Aimee K. Zaas. “Moving toward prime time: host signatures for diagnosis of respiratory infections.” J Infect Dis 212, no. 2 (July 15, 2015): 173–75. https://doi.org/10.1093/infdis/jiv032.Full Text Link to Item
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Rose, Jason J., Deepak Voora, Derek D. Cyr, Joseph E. Lucas, Aimee K. Zaas, Christopher W. Woods, L Kristin Newby, William E. Kraus, and Geoffrey S. Ginsburg. “Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.” Plos One 10, no. 7 (2015): e0132259. https://doi.org/10.1371/journal.pone.0132259.Full Text Open Access Copy Link to Item
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Zaas, Aimee K., Bronwen H. Garner, Ephraim L. Tsalik, Thomas Burke, Christopher W. Woods, and Geoffrey S. Ginsburg. “The current epidemiology and clinical decisions surrounding acute respiratory infections.” Trends Mol Med 20, no. 10 (October 2014): 579–88. https://doi.org/10.1016/j.molmed.2014.08.001.Full Text Link to Item
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Boggan, Joel C., George Cheely, Bimal R. Shah, Randy Heffelfinger, Deanna Springall, Samantha M. Thomas, Aimee Zaas, and Jonathan Bae. “A Novel Approach to Practice-Based Learning and Improvement Using a Web-Based Audit and Feedback Module.” J Grad Med Educ 6, no. 3 (September 2014): 541–46. https://doi.org/10.4300/JGME-D-14-00016.1.Full Text Open Access Copy Link to Item
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Kraft, Bryan D., Claude A. Piantadosi, Ashlee M. Benjamin, Joseph E. Lucas, Aimee K. Zaas, Marisol Betancourt-Quiroz, Christopher W. Woods, et al. “Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates.” Am J Respir Cell Mol Biol 50, no. 5 (May 2014): 995–1004. https://doi.org/10.1165/rcmb.2013-0340OC.Full Text Link to Item
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Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics 41, no. 6 (January 1, 2014): 1358–82. https://doi.org/10.1080/02664763.2013.870138.Full Text
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McClain, Micah T., Lawrence P. Park, Bradly Nicholson, Timothy Veldman, Aimee K. Zaas, Ron Turner, Robert Lambkin-Williams, Anthony S. Gilbert, Geoffrey S. Ginsburg, and Christopher W. Woods. “Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections.” J Clin Virol 58, no. 4 (December 2013): 689–95. https://doi.org/10.1016/j.jcv.2013.09.015.Full Text Link to Item
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Zaas, Aimee K., Thomas Burke, Minhua Chen, Micah McClain, Bradly Nicholson, Timothy Veldman, Ephraim L. Tsalik, et al. “A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.” Sci Transl Med 5, no. 203 (September 18, 2013): 203ra126. https://doi.org/10.1126/scitranslmed.3006280.Full Text Link to Item
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Meade, Lauren B., Kelly J. Caverzagie, Susan R. Swing, Ron R. Jones, Cheryl W. O’Malley, Kenji Yamazaki, and Aimee K. Zaas. “Playing with curricular milestones in the educational sandbox: Q-sort results from an internal medicine educational collaborative.” Acad Med 88, no. 8 (August 2013): 1142–48. https://doi.org/10.1097/ACM.0b013e31829a3967.Full Text Link to Item
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Wang, Hsin-Neng, Andrew M. Fales, Aimee K. Zaas, Christopher W. Woods, Thomas Burke, Geoffrey S. Ginsburg, and Tuan Vo-Dinh. “Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics.” Anal Chim Acta 786 (July 5, 2013): 153–58. https://doi.org/10.1016/j.aca.2013.05.017.Full Text Link to Item
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Desai, Sanjay V., Aimee Zaas, and Joel T. Katz. “Professionalism in graduate medical education.” Jama 309, no. 11 (March 20, 2013): 1110–11. https://doi.org/10.1001/jama.2013.1672.Full Text Link to Item
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Bazot, Cécile, Nicolas Dobigeon, Jean-Yves Tourneret, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “Unsupervised Bayesian linear unmixing of gene expression microarrays.” Bmc Bioinformatics 14 (March 19, 2013): 99. https://doi.org/10.1186/1471-2105-14-99.Full Text Link to Item
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Rose, J. J., D. Voora, D. D. Cyr, J. E. Lucas, A. K. Zaas, L. K. Newby, W. E. Kraus, and G. S. Ginsburg. “Blood Gene Expression Profiling Reveals An Association Between Viral Infection, Platelet Function, And Acute Myocardial Infarction.” American Journal of Respiratory and Critical Care Medicine 187 (January 1, 2013).Link to Item
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Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics, 2013.
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Ahn, Sun Hee, Ephraim L. Tsalik, Derek D. Cyr, Yurong Zhang, Jennifer C. van Velkinburgh, Raymond J. Langley, Seth W. Glickman, et al. “Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.” Plos One 8, no. 1 (2013): e48979. https://doi.org/10.1371/journal.pone.0048979.Full Text Open Access Copy Link to Item
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Woods, Christopher W., Micah T. McClain, Minhua Chen, Aimee K. Zaas, Bradly P. Nicholson, Jay Varkey, Timothy Veldman, et al. “A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.” Plos One 8, no. 1 (2013): e52198. https://doi.org/10.1371/journal.pone.0052198.Full Text Open Access Copy Link to Item
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Biggs, H. M., S. M. Chudgar, C. D. Pfeiffer, K. R. Rice, A. K. Zaas, and C. R. Wolfe. “Disseminated Mycobacterium immunogenum infection presenting with septic shock and skin lesions in a renal transplant recipient.” Transpl Infect Dis 14, no. 4 (August 2012): 415–21. https://doi.org/10.1111/j.1399-3062.2012.00730.x.Full Text Link to Item
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Carin, Lawrence, Alfred Hero, Joseph Lucas, David Dunson, Minhua Chen, Ricardo Heñao, Arnau Tibau-Puig, Aimee Zaas, Christopher W. Woods, and Geoffrey S. Ginsburg. “High-Dimensional Longitudinal Genomic Data: An analysis used for monitoring viral infections.” Ieee Signal Process Mag 29, no. 1 (January 1, 2012): 108–23. https://doi.org/10.1109/MSP.2011.943009.Full Text Link to Item
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Shapiro, Rebecca S., Aimee K. Zaas, Marisol Betancourt-Quiroz, John R. Perfect, and Leah E. Cowen. “The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance.” Plos One 7, no. 9 (2012): e44734. https://doi.org/10.1371/journal.pone.0044734.Full Text Open Access Copy Link to Item
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Hanson, Kimberly E., Christopher D. Pfeiffer, Erika D. Lease, Alfred H. Balch, Aimee K. Zaas, John R. Perfect, and Barbara D. Alexander. “β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study.” Plos One 7, no. 8 (2012): e42282. https://doi.org/10.1371/journal.pone.0042282.Full Text Open Access Copy Link to Item
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Peltz, Gary, Aimee K. Zaas, Ming Zheng, Norma V. Solis, Mason X. Zhang, Hong-Hsing Liu, Yajing Hu, et al. “Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.” Infect Immun 79, no. 11 (November 2011): 4472–79. https://doi.org/10.1128/IAI.05666-11.Full Text Link to Item
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Huang, Yongsheng, Aimee K. Zaas, Arvind Rao, Nicolas Dobigeon, Peter J. Woolf, Timothy Veldman, N Christine Øien, et al. “Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection.” Plos Genet 7, no. 8 (August 2011): e1002234. https://doi.org/10.1371/journal.pgen.1002234.Full Text Open Access Copy Link to Item
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Chen, Minhua, David Carlson, Aimee Zaas, Christopher W. Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, and Lawrence Carin. “Detection of viruses via statistical gene expression analysis.” Ieee Trans Biomed Eng 58, no. 3 (March 2011): 468–79. https://doi.org/10.1109/TBME.2010.2059702.Full Text Link to Item
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Chen, Minhua, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Joseph Lucas, David Dunson, and Lawrence Carin. “Predicting Viral Infection From High-Dimensional Biomarker Trajectories.” J Am Stat Assoc 106, no. 496 (January 1, 2011): 1259–79. https://doi.org/10.1198/jasa.2011.ap10611.Full Text Link to Item
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Puig, A. T., A. Wiesel, A. K. Zaas, C. W. Woods, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor analysis-application to longitudinal gene expression.” Ieee Transactions on Signal Processing 59, no. 9 (January 1, 2011): 4447–58. https://doi.org/10.1109/TSP.2011.2157146.Full Text
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Puig, A. T., A. Wiesel, A. Zaas, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor discovery from misaligned data.” 2010 Ieee Sensor Array and Multichannel Signal Processing Workshop, Sam 2010, December 20, 2010, 209–12. https://doi.org/10.1109/SAM.2010.5606736.Full Text
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Chen, Bo, Minhua Chen, John Paisley, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, David Dunson, and Lawrence Carin. “Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies.” Bmc Bioinformatics 11 (November 9, 2010): 552. https://doi.org/10.1186/1471-2105-11-552.Full Text Open Access Copy Link to Item
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Paisley, J., A. Zaas, C. W. Woods, G. S. Ginsburg, and L. Carin. “A stick-breaking construction of the beta process.” Icml 2010 Proceedings, 27th International Conference on Machine Learning, September 17, 2010, 847–54.
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Ahn, Sun-Hee, Hitesh Deshmukh, Nicole Johnson, Lindsay G. Cowell, Thomas H. Rude, William K. Scott, Charlotte L. Nelson, et al. “Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.” Plos Pathog 6, no. 9 (September 2, 2010): e1001088. https://doi.org/10.1371/journal.ppat.1001088.Full Text Open Access Copy Link to Item
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LaFayette, Shantelle L., Cathy Collins, Aimee K. Zaas, Wiley A. Schell, Marisol Betancourt-Quiroz, AA Leslie Gunatilaka, John R. Perfect, and Leah E. Cowen. “PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.” Plos Pathog 6, no. 8 (August 26, 2010): e1001069. https://doi.org/10.1371/journal.ppat.1001069.Full Text Open Access Copy Link to Item
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Pfeiffer, Christopher D., Guillermo Garcia-Effron, Aimee K. Zaas, John R. Perfect, David S. Perlin, and Barbara D. Alexander. “Breakthrough invasive candidiasis in patients on micafungin.” J Clin Microbiol 48, no. 7 (July 2010): 2373–80. https://doi.org/10.1128/JCM.02390-09.Full Text Link to Item
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Zaas, Aimee K., Hamza Aziz, Joseph Lucas, John R. Perfect, and Geoffrey S. Ginsburg. “Blood gene expression signatures predict invasive candidiasis.” Sci Transl Med 2, no. 21 (March 3, 2010): 21ra17. https://doi.org/10.1126/scitranslmed.3000715.Full Text Link to Item
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Zaas, A. K., M. Chen, A. O. Hero, J. Lucas, L. Carin, and G. S. Ginsburg. “Response: Improving Development of the Molecular Signature for Diagnosis of Acute Respiratory Viral Infections.” Cell Host and Microbe 7, no. 2 (February 18, 2010): 102. https://doi.org/10.1016/j.chom.2010.02.002.Full Text
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Zaas, Aimee K., Minhua Chen, Jay Varkey, Timothy Veldman, Alfred O. Hero, Joseph Lucas, Yongsheng Huang, et al. “Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.” Cell Host Microbe 6, no. 3 (September 17, 2009): 207–17. https://doi.org/10.1016/j.chom.2009.07.006.Full Text Link to Item
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Singh, Sheena D., Nicole Robbins, Aimee K. Zaas, Wiley A. Schell, John R. Perfect, and Leah E. Cowen. “Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.” Plos Pathog 5, no. 7 (July 2009): e1000532. https://doi.org/10.1371/journal.ppat.1000532.Full Text Link to Item
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Shapiro, Rebecca S., Priya Uppuluri, Aimee K. Zaas, Cathy Collins, Heather Senn, John R. Perfect, Joseph Heitman, and Leah E. Cowen. “Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling.” Curr Biol 19, no. 8 (April 28, 2009): 621–29. https://doi.org/10.1016/j.cub.2009.03.017.Full Text Link to Item
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Cowen, Leah E., Sheena D. Singh, Julia R. Köhler, Cathy Collins, Aimee K. Zaas, Wiley A. Schell, Hamza Aziz, et al. “Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.” Proc Natl Acad Sci U S A 106, no. 8 (February 24, 2009): 2818–23. https://doi.org/10.1073/pnas.0813394106.Full Text Link to Item
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Baddley, J. W., J. R. Perfect, R. A. Oster, R. A. Larsen, G. A. Pankey, H. Henderson, D. W. Haas, et al. “Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease.” Eur J Clin Microbiol Infect Dis 27, no. 10 (October 2008): 937–43. https://doi.org/10.1007/s10096-008-0529-z.Full Text Link to Item
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Zaas, Aimee K. “Echinocandins: a wealth of choice--how clinically different are they?” Curr Opin Infect Dis 21, no. 4 (August 2008): 426–32. https://doi.org/10.1097/QCO.0b013e328307c79c.Full Text Link to Item
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Zaas, Aimee K., Guochun Liao, Jason W. Chien, Clarice Weinberg, David Shore, Steven S. Giles, Kieren A. Marr, et al. “Plasminogen alleles influence susceptibility to invasive aspergillosis.” Plos Genet 4, no. 6 (June 20, 2008): e1000101. https://doi.org/10.1371/journal.pgen.1000101.Full Text Link to Item
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Garantziotis, Stavros, John W. Hollingsworth, Aimee K. Zaas, and David A. Schwartz. “The effect of toll-like receptors and toll-like receptor genetics in human disease.” Annu Rev Med 59 (2008): 343–59. https://doi.org/10.1146/annurev.med.59.061206.112455.Full Text Link to Item
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Giles, Steven S., Aimee K. Zaas, Mike F. Reidy, John R. Perfect, and Jo Rae Wright. “Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.” Plos One 2, no. 12 (December 26, 2007): e1370. https://doi.org/10.1371/journal.pone.0001370.Full Text Link to Item
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Reddy, Anita J., Aimee K. Zaas, Kimberly E. Hanson, and Scott M. Palmer. “A single-center experience with ganciclovir-resistant cytomegalovirus in lung transplant recipients: treatment and outcome.” J Heart Lung Transplant 26, no. 12 (December 2007): 1286–92. https://doi.org/10.1016/j.healun.2007.09.012.Full Text Link to Item
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Hollingsworth, J. W., S. Shofer, and A. Zaas. “Successful treatment of Ochroconis gallopavum infection in an immunocompetent host.” Infection 35, no. 5 (October 2007): 367–69. https://doi.org/10.1007/s15010-007-6054-7.Full Text Link to Item
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Zaas, A. K., and J. R. Perfect. “Pulmonary fungal infections: Making the diagnosis.” Infections in Medicine 24, no. 4 (April 1, 2007): 156–68.
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Dodds Ashley, E. S., A. K. Zaas, A. F. Fang, B. Damle, and J. R. Perfect. “Comparative pharmacokinetics of voriconazole administered orally as either crushed or whole tablets.” Antimicrob Agents Chemother 51, no. 3 (March 2007): 877–80. https://doi.org/10.1128/AAC.01263-06.Full Text Link to Item
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Aziz, Hamza, Aimee Zaas, and Geoffrey S. Ginsburg. “Peripheral blood gene expression profiling for cardiovascular disease assessment.” Genomic Med 1, no. 3–4 (2007): 105–12. https://doi.org/10.1007/s11568-008-9017-x.Full Text Link to Item
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Zaas, Aimee K., Elizabeth S. Dodds Ashley, Barbara D. Alexander, Melissa D. Johnson, and John R. Perfect. “Caspofungin for invasive candidiasis at a tertiary care medical center.” Am J Med 119, no. 11 (November 2006): 993.e1-993.e6. https://doi.org/10.1016/j.amjmed.2006.02.029.Full Text Link to Item
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Zaas, Aimee K. “Host genetics affect susceptibility to invasive aspergillosis.” Med Mycol 44, no. Supplement_1 (September 1, 2006): S55–60. https://doi.org/10.1080/13693780600865481.Full Text Link to Item
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Zaas, A. K., and B. D. Alexander. “Galactomannan and advances in fungal diagnostics.” Current Opinion in Organ Transplantation 10, no. 4 (December 1, 2005): 307–11. https://doi.org/10.1097/01.mot.0000187102.18780.b0.Full Text
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Steinbach, William J., John R. Perfect, Christopher H. Cabell, Vance G. Fowler, G Ralph Corey, Jennifer S. Li, Aimee K. Zaas, and Daniel K. Benjamin. “A meta-analysis of medical versus surgical therapy for Candida endocarditis.” J Infect 51, no. 3 (October 2005): 230–47. https://doi.org/10.1016/j.jinf.2004.10.016.Full Text Link to Item
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Zaas, Aimee K., and David A. Schwartz. “Innate immunity and the lung: defense at the interface between host and environment.” Trends Cardiovasc Med 15, no. 6 (August 2005): 195–202. https://doi.org/10.1016/j.tcm.2005.07.001.Full Text Link to Item
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Zaas, Aimee K., and Barbara D. Alexander. “Echinocandins: role in antifungal therapy, 2005.” Expert Opin Pharmacother 6, no. 10 (August 2005): 1657–68. https://doi.org/10.1517/14656566.6.10.1657.Full Text Link to Item
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Zaas, Aimee K., and William J. Steinbach. “Micafungin: the US perspective.” Expert Rev Anti Infect Ther 3, no. 2 (April 2005): 183–90. https://doi.org/10.1586/14787210.3.2.183.Full Text Link to Item
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Zaas, Aimee K., and Barbara D. Alexander. “New developments in the diagnosis and treatment of infections in lung transplant recipients.” Respir Care Clin N Am 10, no. 4 (December 2004): 531–47. https://doi.org/10.1016/j.rcc.2004.06.001.Full Text Link to Item
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Steinbach, William J., Daniel K. Benjamin, Scott A. Trasi, Jackie L. Miller, Wiley A. Schell, Aimee K. Zaas, W Michael Foster, and John R. Perfect. “Value of an inhalational model of invasive aspergillosis.” Med Mycol 42, no. 5 (October 2004): 417–25. https://doi.org/10.1080/13693780410001712034.Full Text Link to Item
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Steinbach, W. J., and A. K. Zaas. “Newer animal models of Aspergillus and Candida infections.” Drug Discovery Today: Disease Models 1, no. 1 (January 1, 2004): 87–93. https://doi.org/10.1016/j.ddmod.2004.03.001.Full Text
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Zaas, Aimee K., Molly Boyce, Wiley Schell, Barbara Alexander Lodge, Jackie L. Miller, and John R. Perfect. “Risk of fungemia due to Rhodotorula and antifungal susceptibility testing of Rhodotorula isolates.” J Clin Microbiol 41, no. 11 (November 2003): 5233–35. https://doi.org/10.1128/JCM.41.11.5233-5235.2003.Full Text Link to Item
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Toonkel, Rebecca, and Aimee Zaas. “Cases from the Osler Medical Service at Johns Hopkins University.” Am J Med 115, no. 6 (October 15, 2003): 497–500. https://doi.org/10.1016/j.amjmed.2003.08.005.Full Text Link to Item
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Zaas, A. K., and J. R. Perfect. “Pulmonary fungal infections: Making the diagnosis.” Journal of Respiratory Diseases 24, no. 10 (October 1, 2003): 433–44.
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Piccini, Jonathan, and Aimee Zaas. “Cases from the Osler Medical Service at Johns Hopkins University. Diffuse colonic angiodysplasia with chronic iron deficiency anemia.” Am J Med 115, no. 3 (August 15, 2003): 245–48. https://doi.org/10.1016/s0002-9343(03)00369-3.Full Text Link to Item
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Piccini, Jonathan, and Aimee Zaas. “Cases from the Osler Medical Service at Johns Hopkins University. Digitalis toxicity with bidirectional ventricular tachycardia.” Am J Med 115, no. 1 (July 2003): 70–71. https://doi.org/10.1016/s0002-9343(03)00331-0.Full Text Link to Item
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Passaretti, Catherine, and Aimee Zaas. “Cases from the Osler medical service at Johns Hopkins University.” Am J Med 114, no. 7 (May 2003): 613–16. https://doi.org/10.1016/s0002-9343(03)00162-1.Full Text Link to Item
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McGirt, Matthew J., Aimee Zaas, Herbert E. Fuchs, Timothy M. George, Keith Kaye, and Daniel J. Sexton. “Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens.” Clin Infect Dis 36, no. 7 (April 1, 2003): 858–62. https://doi.org/10.1086/368191.Full Text Link to Item
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Grow, Robert W., and Aimee Zaas. “Cases from the Osler Medical Service at Johns Hopkins University.” Am J Med 114, no. 2 (February 1, 2003): 153–55. https://doi.org/10.1016/s0002-9343(03)00009-3.Full Text Link to Item
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Le, Dung, and Aimee Zaas. “Cases from the Osler Medical Service at Johns Hopkins University. Left atrial myxoma.” Am J Med 113, no. 8 (December 1, 2002): 694–96. https://doi.org/10.1016/s0002-9343(02)01442-0.Full Text Link to Item
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Zaas, Aimee K., Xiaoyan Song, Pamela Tucker, and Trish M. Perl. “Risk factors for development of vancomycin-resistant enterococcal bloodstream infection in patients with cancer who are colonized with vancomycin-resistant enterococci.” Clin Infect Dis 35, no. 10 (November 15, 2002): 1139–46. https://doi.org/10.1086/342904.Full Text Link to Item
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Zaas, A., P. Scheel, A. Venbrux, and D. B. Hellmann. “Large artery vasculitis following recombinant hepatitis B vaccination: 2 cases.” J Rheumatol 28, no. 5 (May 2001): 1116–20.Link to Item
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Zaas, A. K., X. Y. Song, T. M. Perl, and P. C. Tucker. “Nosocomial vancomycin-resistant enterococcal blood stream infection (VRE-BSI) development in oncology patients colonized with vancomycin-resistant Enterococci(VRE-C).” Clinical Infectious Diseases 31, no. 1 (July 1, 2000): 278–278.Link to Item
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Book Sections
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Steinbach, W. J. “Clinical aspects of the genus aspergillus.” In The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods, 359–75, 2007. https://doi.org/10.1201/9781420008517.Full Text
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Conference Papers
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Boggan, Joel C., Vaishali A. Patel, and Aimee K. Zaas. “A BLAST FROM THE PAST: RESIDENT AND FACULTY ATTITUDES WITH RE-INSTITUTION OF 24+4-HOUR CALL AT ONE MEDICAL CENTER.” In Journal of General Internal Medicine, 30:S482–S482. SPRINGER, 2015.Link to Item
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Willett, Lisa L., Andrew J. Halvorsen, Michael Adams, Vineet M. Arora, Karen Chacko, Furman S. McDonald, Amy Oxentenko, Sara L. Swenson, Aimee K. Zaas, and Saima Chaudhry. “DECLINING PASS RATES OF THE AMERICAN BOARD OF INTERNAL MEDICINE CERTIFICATION EXAMINATION: PROGRAM DIRECTORS' PERSPECTIVES.” In Journal of General Internal Medicine, 30:S131–32. SPRINGER, 2015.Link to Item
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Meade, Lauren B., Kathleen A. Heist, Ron Jones, Cheryl O’Malley, Kenji Yamazaki, and Aimee K. Zaas. “A SAFE AND EFFECTIVE DISCHARGE CURRICULUM IMPLEMENTED IN ELEVEN INTERNAL MEDICINE PROGRAMS OF THE EDUCATIONAL RESEARCH OUTCOMES COLLABORATIVE.” In Journal of General Internal Medicine, 30:S486–S486. SPRINGER, 2015.Link to Item
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Cho, Alex H., Mark Dakkak, Adia K. Ross, Wei Duan-Porter, Lynn Bowlby, Daniella A. Zipkin, Lawrence Greenblatt, et al. “REDESIGNTNG A RESIDENT CONTINUITY CLINIC TO PROVIDE EFFECTIVE POPULATION HEALTH MANAGEMENT.” In Journal of General Internal Medicine, 29:S494–S494. SPRINGER, 2014.Link to Item
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Boole, Lindsay, Jessica Seidelman, Aimee Zaas, George Cheely, Saumil Chudgar, Jeffrey Clarke, David Gallagher, et al. “Residents Finding Their Roots: Resident Workshops to Improve Patient Safety on the Wards while Teaching Residents Root Cause Analysis,” 2014.Open Access Copy
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Broderick-Forsgren, K., W. Hunter, P. Sharma, R. Schulteis, A. Zaas, and J. G. Bae. “Doctor Who? A Study of Patient Provider Awareness.” In Journal of Hospital Medicine, Vol. 9. John Wiley & Sons Inc., n.d.
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- Teaching & Mentoring
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Recent Courses
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