Skip to main content

Aiping Ding

Assistant Professor of Radiology
Radiology
2424 Erwin Road, Suite 302 (DUMC 2731), Durham, NC 27705
2424 Erwin Road, Suite 302 (DUMC 2731), Durham, NC 27705

Selected Publications


Making CT Dose Monitoring Meaningful: Augmenting Dose with Imaging Quality.

Journal Article Tomography · April 7, 2023 Due to the concerns about radiation dose associated with medical imaging, radiation dose monitoring systems (RDMSs) are now utilized by many radiology providers to collect, process, analyze, and manage radiation dose-related information. Currently, most co ... Full text Open Access Link to item Cite

Key Performance Indicators for Quality Imaging Practice: Why, What, and How.

Journal Article J Am Coll Radiol · January 2022 A common trend across health care organizations is the development of key performance indicators (KPIs) for characterizing quality, identifying areas in need of change, and quantifying the impact of change. This article outlines a list of KPIs that can be ... Full text Link to item Cite

Patient-based Performance Assessment for Pediatric Abdominal CT: An Automated Monitoring System Based on Lesion Detectability and Radiation Dose.

Journal Article Acad Radiol · February 2021 RATIONALE AND OBJECTIVE: To deploy an automated tool for evaluating pediatric body computed tomography (CT) performance utilizing metrics of radiation dose and image quality for the task of liver lesion detection. MATERIALS AND METHODS: This IRB approved r ... Full text Link to item Cite

CT Practice Monitoring

Chapter · December 16, 2019 This book is an ideal resource for practitioners of CT applications in medicine, including physicians, trainees, engineers, and scientists. This book offers a comprehensive and topical depiction of advances in CT imaging. ... Link to item Cite

A Data-Centric Strategy for Developing CT Dose and Noise Reference Levels from Clinical Patient Populations

Conference · November 27, 2018 PURPOSE To develop a data-centric strategy solution for developing CT dose and noise reference levels across large clinical patient populations and in CT scanners. METHOD AND MATERIALS This IRB-exempt study evaluated CT abdominopelvic (AP)-related examin ... Cite

Robustness and Accuracy of An Automated Solution for Measuring Image Noise, Spatial Resolution, Contrast, and Dose in Clinical CT Images: Efforts Towards Patient-Specific Quantifications of CT Image Quality and Radiation Dose

Conference Medical Physics · June 30, 2017 Purpose: To develop a robust and accurate automated solution for measuring image noise, spatial resolution, contrast, and radiation dose using clinical patient CT images. Methods: An automated infrastructure has been developed to measure the image quality ... Cite

Image Quality Monitoring: Variability in Contrast Enhancement Across a Clinical Population

Conference Medical Physics · June 30, 2017 Purpose: Iodinated contrast agents are commonly used in computed tomography (CT) to delineate vasculature and blood perfusion by enhancement of Hounsfield unit values. Contrast-enhancement is affected by anatomical and physiological factors, and varies acr ... Cite

Pixel response-based EPID dosimetry for patient specific QA.

Journal Article Journal of applied clinical medical physics · January 2017 Increasing use of high dose rate, flattening filter free (FFF), and/or small-sized field beams presents a significant challenge to the medical physics community. In this work, we develop a strategy of using a high spatial resolution and high frame rate amo ... Full text Cite

Development of an accurate EPID-based output measurement and dosimetric verification tool for electron beam therapy.

Journal Article Medical physics · July 2015 PurposeTo develop an efficient and robust tool for output measurement and absolute dose verification of electron beam therapy by using a high spatial-resolution and high frame-rate amorphous silicon flat panel electronic portal imaging device (EPI ... Full text Cite

VirtualDose: a software for reporting organ doses from CT for adult and pediatric patients.

Journal Article Physics in medicine and biology · July 2015 Featured Publication This paper describes the development and testing of VirtualDose--a software for reporting organ doses for adult and pediatric patients who undergo x-ray computed tomography (CT) examinations. The software is based on a comprehensive database of organ doses ... Full text Cite

The profound effects of patient arm positioning on organ doses from CT procedures calculated using Monte Carlo simulations and deformable phantoms.

Journal Article Radiation protection dosimetry · April 2015 The purpose of this study was to evaluate the organ dose differences caused by the arms-raised and arms-lowered postures for multidetector computed tomography procedures. Organ doses were calculated using computational phantoms and Monte Carlo simulations. ... Full text Cite

Independent calculation of monitor units for VMAT and SPORT.

Journal Article Medical physics · February 2015 PurposeDose and monitor units (MUs) represent two important facets of a radiation therapy treatment. In current practice, verification of a treatment plan is commonly done in dose domain, in which a phantom measurement or forward dose calculation ... Full text Cite

A dose-reconstruction study of the 1997 Sarov criticality accident using animated dosimetry techniques.

Journal Article Health physics · May 2014 Most computational human phantoms are static, representing a standing individual. There are, however, cases when these phantoms fail to represent accurately the detailed effects on dose that result from considering varying human posture and even whole sequ ... Full text Cite

TU‐G‐103‐01: Monte Carlo Simulation and Dose Calculation of Chest CT Scan with Tube Current Modulation

Conference Medical Physics · January 1, 2013 Purpose: To establish the method of organ dose calculation through Monte Carlo simulations for patients taking CT scans with tube current modulation (TCM), and to give the dose results as well as the preliminary comparison of the dose with TCM and the dose ... Full text Cite

TU‐G‐103‐02: Clinical Evaluation of VirtualDose — a Software for Tracking and Reporting CTDI, DLP, Organ and Effective Dose for Adult and Pediatric Patient

Conference Medical Physics · January 1, 2013 Purpose: To update the development and clinical testing of a new Software as a Service (SaaS) ‐ VirtualDose for tracking and reporting CT doses. Methods: Incorporating SaaS technology and the comprehensive original dose data derived from Monte Carlo simula ... Full text Cite

SU-E-T-493: Accelerated Monte Carlo Methods for Photon Dosimetry Using a Dual-GPU System and CUDA.

Journal Article Medical physics · June 2012 PurposeTo develop a Graphics Processing Unit (GPU) based Monte Carlo (MC) code that accelerates dose calculations on a dual-GPU system.MethodsWe simulated a clinical case of prostate cancer treatment. A voxelized abdomen phantom derived f ... Full text Cite

Extension of RPI-adult male and female computational phantoms to obese patients and a Monte Carlo study of the effect on CT imaging dose.

Journal Article Physics in medicine and biology · May 2012 Featured Publication Although it is known that obesity has a profound effect on x-ray computed tomography (CT) image quality and patient organ dose, quantitative data describing this relationship are not currently available. This study examines the effect of obesity on the cal ... Full text Cite

WE‐A‐218‐09: A Comprehensive CT Organ Dose Database for Weight‐Specific Adult and Pediatric Patients

Conference Medical Physics · January 1, 2012 Purpose: To describe the joint effort to develop a comprehensive CT organ dose database for weight‐specific adult and pediatric patients. Methods: Two validated CT scanner models (GE LightSpeed Pro 16 and Siemens SOMATOM sensation 16) operated at different ... Full text Cite

MO‐F‐213CD‐03: Design and Testing of the VirtualDose Software Under the Software as a Service (SaaS) Platform for Tracking and Reporting CT Doses

Conference Medical Physics · January 1, 2012 Purpose: To report recent progress toward developing and testing the VirtualDose software under the ‘Software as a Service (SaaS)’ platform for tracking and reporting patient CT doses. Methods: Many of existing tools for reporting CT dose are based on data ... Full text Cite

MO‐F‐213CD‐01: GPU‐Based Monte Carlo Methods for Accelerating Radiographic and CT Imaging Dose Calculations: Feasibility and Scalability

Conference Medical Physics · January 1, 2012 Purpose: To develop a Graphics Processing Unit (GPU) based Monte Carlo (MC) code that uses a dual‐GPU system to accelerate radiographic simulation and CT imaging dose calculations. Methods: We considered two clinical cases, a chest x‐ray radiography and an ... Full text Cite

Making CT Dose Monitoring Meaningful: Augmenting Dose with Imaging Quality.

Journal Article Tomography · April 7, 2023 Due to the concerns about radiation dose associated with medical imaging, radiation dose monitoring systems (RDMSs) are now utilized by many radiology providers to collect, process, analyze, and manage radiation dose-related information. Currently, most co ... Full text Open Access Link to item Cite

Key Performance Indicators for Quality Imaging Practice: Why, What, and How.

Journal Article J Am Coll Radiol · January 2022 A common trend across health care organizations is the development of key performance indicators (KPIs) for characterizing quality, identifying areas in need of change, and quantifying the impact of change. This article outlines a list of KPIs that can be ... Full text Link to item Cite

Patient-based Performance Assessment for Pediatric Abdominal CT: An Automated Monitoring System Based on Lesion Detectability and Radiation Dose.

Journal Article Acad Radiol · February 2021 RATIONALE AND OBJECTIVE: To deploy an automated tool for evaluating pediatric body computed tomography (CT) performance utilizing metrics of radiation dose and image quality for the task of liver lesion detection. MATERIALS AND METHODS: This IRB approved r ... Full text Link to item Cite

CT Practice Monitoring

Chapter · December 16, 2019 This book is an ideal resource for practitioners of CT applications in medicine, including physicians, trainees, engineers, and scientists. This book offers a comprehensive and topical depiction of advances in CT imaging. ... Link to item Cite

A Data-Centric Strategy for Developing CT Dose and Noise Reference Levels from Clinical Patient Populations

Conference · November 27, 2018 PURPOSE To develop a data-centric strategy solution for developing CT dose and noise reference levels across large clinical patient populations and in CT scanners. METHOD AND MATERIALS This IRB-exempt study evaluated CT abdominopelvic (AP)-related examin ... Cite

Robustness and Accuracy of An Automated Solution for Measuring Image Noise, Spatial Resolution, Contrast, and Dose in Clinical CT Images: Efforts Towards Patient-Specific Quantifications of CT Image Quality and Radiation Dose

Conference Medical Physics · June 30, 2017 Purpose: To develop a robust and accurate automated solution for measuring image noise, spatial resolution, contrast, and radiation dose using clinical patient CT images. Methods: An automated infrastructure has been developed to measure the image quality ... Cite

Image Quality Monitoring: Variability in Contrast Enhancement Across a Clinical Population

Conference Medical Physics · June 30, 2017 Purpose: Iodinated contrast agents are commonly used in computed tomography (CT) to delineate vasculature and blood perfusion by enhancement of Hounsfield unit values. Contrast-enhancement is affected by anatomical and physiological factors, and varies acr ... Cite

Pixel response-based EPID dosimetry for patient specific QA.

Journal Article Journal of applied clinical medical physics · January 2017 Increasing use of high dose rate, flattening filter free (FFF), and/or small-sized field beams presents a significant challenge to the medical physics community. In this work, we develop a strategy of using a high spatial resolution and high frame rate amo ... Full text Cite

Development of an accurate EPID-based output measurement and dosimetric verification tool for electron beam therapy.

Journal Article Medical physics · July 2015 PurposeTo develop an efficient and robust tool for output measurement and absolute dose verification of electron beam therapy by using a high spatial-resolution and high frame-rate amorphous silicon flat panel electronic portal imaging device (EPI ... Full text Cite

VirtualDose: a software for reporting organ doses from CT for adult and pediatric patients.

Journal Article Physics in medicine and biology · July 2015 Featured Publication This paper describes the development and testing of VirtualDose--a software for reporting organ doses for adult and pediatric patients who undergo x-ray computed tomography (CT) examinations. The software is based on a comprehensive database of organ doses ... Full text Cite

The profound effects of patient arm positioning on organ doses from CT procedures calculated using Monte Carlo simulations and deformable phantoms.

Journal Article Radiation protection dosimetry · April 2015 The purpose of this study was to evaluate the organ dose differences caused by the arms-raised and arms-lowered postures for multidetector computed tomography procedures. Organ doses were calculated using computational phantoms and Monte Carlo simulations. ... Full text Cite

Independent calculation of monitor units for VMAT and SPORT.

Journal Article Medical physics · February 2015 PurposeDose and monitor units (MUs) represent two important facets of a radiation therapy treatment. In current practice, verification of a treatment plan is commonly done in dose domain, in which a phantom measurement or forward dose calculation ... Full text Cite

A dose-reconstruction study of the 1997 Sarov criticality accident using animated dosimetry techniques.

Journal Article Health physics · May 2014 Most computational human phantoms are static, representing a standing individual. There are, however, cases when these phantoms fail to represent accurately the detailed effects on dose that result from considering varying human posture and even whole sequ ... Full text Cite

TU‐G‐103‐01: Monte Carlo Simulation and Dose Calculation of Chest CT Scan with Tube Current Modulation

Conference Medical Physics · January 1, 2013 Purpose: To establish the method of organ dose calculation through Monte Carlo simulations for patients taking CT scans with tube current modulation (TCM), and to give the dose results as well as the preliminary comparison of the dose with TCM and the dose ... Full text Cite

TU‐G‐103‐02: Clinical Evaluation of VirtualDose — a Software for Tracking and Reporting CTDI, DLP, Organ and Effective Dose for Adult and Pediatric Patient

Conference Medical Physics · January 1, 2013 Purpose: To update the development and clinical testing of a new Software as a Service (SaaS) ‐ VirtualDose for tracking and reporting CT doses. Methods: Incorporating SaaS technology and the comprehensive original dose data derived from Monte Carlo simula ... Full text Cite

SU-E-T-493: Accelerated Monte Carlo Methods for Photon Dosimetry Using a Dual-GPU System and CUDA.

Journal Article Medical physics · June 2012 PurposeTo develop a Graphics Processing Unit (GPU) based Monte Carlo (MC) code that accelerates dose calculations on a dual-GPU system.MethodsWe simulated a clinical case of prostate cancer treatment. A voxelized abdomen phantom derived f ... Full text Cite

Extension of RPI-adult male and female computational phantoms to obese patients and a Monte Carlo study of the effect on CT imaging dose.

Journal Article Physics in medicine and biology · May 2012 Featured Publication Although it is known that obesity has a profound effect on x-ray computed tomography (CT) image quality and patient organ dose, quantitative data describing this relationship are not currently available. This study examines the effect of obesity on the cal ... Full text Cite

WE‐A‐218‐09: A Comprehensive CT Organ Dose Database for Weight‐Specific Adult and Pediatric Patients

Conference Medical Physics · January 1, 2012 Purpose: To describe the joint effort to develop a comprehensive CT organ dose database for weight‐specific adult and pediatric patients. Methods: Two validated CT scanner models (GE LightSpeed Pro 16 and Siemens SOMATOM sensation 16) operated at different ... Full text Cite

MO‐F‐213CD‐03: Design and Testing of the VirtualDose Software Under the Software as a Service (SaaS) Platform for Tracking and Reporting CT Doses

Conference Medical Physics · January 1, 2012 Purpose: To report recent progress toward developing and testing the VirtualDose software under the ‘Software as a Service (SaaS)’ platform for tracking and reporting patient CT doses. Methods: Many of existing tools for reporting CT dose are based on data ... Full text Cite

MO‐F‐213CD‐01: GPU‐Based Monte Carlo Methods for Accelerating Radiographic and CT Imaging Dose Calculations: Feasibility and Scalability

Conference Medical Physics · January 1, 2012 Purpose: To develop a Graphics Processing Unit (GPU) based Monte Carlo (MC) code that uses a dual‐GPU system to accelerate radiographic simulation and CT imaging dose calculations. Methods: We considered two clinical cases, a chest x‐ray radiography and an ... Full text Cite

SU‐C‐217A‐03: Position Sensitivity of Calculated Dose‐Length‐Product‐To‐Effective‐ Dose Conversion Factors in Computed Tomography Examination

Conference Medical Physics · January 1, 2012 Purpose: To quantify the sensitivity of Dose Length Product to Effective Dose conversion factors (k‐factors) to scan length and position. Methods: To convert the recorded Dose Length Product (DLP) to an estimate of Effective Dose (E), a set of conversion f ... Full text Cite

COMPARISON OF PARTICLE-TRACKING FEATURES IN GEANT4 AND MCNPX CODES FOR APPLICATIONS IN MAPPING OF PROTON RANGE UNCERTAINTY.

Conference Nuclear technology · July 2011 The accuracy of proton therapy is partially limited by uncertainties that result from changing pathological conditions in the patient such as tumor motion and shrinkage. These uncertainties can be minimized with the help of a time-resolved range telescope. ... Full text Cite

TH‐E‐211‐06: Further Development of VirtualDose Software for CT Dose Assessment: Realistic Phantoms and Smartphone User Interfaces

Conference Medical Physics · January 1, 2011 Purpose: To demonstrate the feasibility of a new software applications for both PC and smartphone users to easily track patient CT doses. Methods: Many of existing tools for reporting CT dose are based on data derived from stylistic phantoms. Based on exte ... Full text Cite

TH‐A‐214‐06: Organ Dose Weighting Methods for Tube Current Modulated CT Exams: Demonstration Using Adult Patient Phantoms

Conference Medical Physics · January 1, 2011 Purpose: To demonstrate a method to estimate organ doses from tube current modulated (TCM) CT examinations using angular organ dose weighting. Method and Materials: An extensive set of Monte Carlo dose calcualtions has become available in recent years usin ... Full text Cite

TH‐A‐214‐04: Impact of Body Size of Obese Patients on PET/CT Dose Estimates: Monte Carlo Calculations Using a Set of BMI‐Adjustable Phantoms

Conference Medical Physics · January 1, 2011 Purpose: To assess the effect of obese patient's body mass index (BMI) on organ doses from CT and PET exams. Methods: A set of 5 computational phantoms with different BMIs were created for PET and CT dose calculations using the Monte Carlo N‐Particle Exten ... Full text Cite

Monte Carlo calculation of imaging doses from diagnostic multidetector CT and kilovoltage cone-beam CT as part of prostate cancer treatment plans.

Journal Article Medical physics · December 2010 PurposeTo calculate imaging doses to the rectum, bladder, and femoral heads as part of a prostate cancer treatment plans, assuming an image guided radiation therapy (IGRT) procedure involving either the multidetector CT (MDCT) or kilovoltage cone- ... Full text Cite

TH‐C‐201B‐04: Methods to Account for Imaging Doses from Diagnostic MDCT or Kilovoltage CBCT in Prostate Treatment Planning: Monte Carlo Studies Using Scanner Models and Patient‐Specific Anatomy

Conference Medical Physics · January 1, 2010 Purpose: MDCT and kilovoltage CBCT are increasingly used in IGRT. AAPM TG‐75 has made a series of recommendations on imaging doses. Recent studies have focused on an inclusion of imaging doses using a radiation treatment planning (RTP) system. This paper d ... Full text Cite

SU‐GG‐J‐148: Evaluation of Performance of a Conceptual Time‐Resolved Proton Range Telescope for In‐Room Respiration Monitoring Using Monte Carlo Simulations and 4DCT Patient Data

Conference Medical Physics · January 1, 2010 Purpose: To demonstrate the feasibility to perform and optimize a time‐resolved proton range telescope (TRRT) in localization of moving lung tumors and quantification of proton range variations. Method: A TRRT is designed to detect transmission protons and ... Full text Cite

SU‐GG‐T‐404: Demonstration of the Ability to Morph an Existing Whole‐Body Phantom to a Different Individual

Conference Medical Physics · January 1, 2010 Purpose: Although patient‐specific partial‐body phantoms can be created from CT data, whole‐body phantoms are desired for the assessment of organ doses in CT, internal nuclear medicine and external‐beam radiation treatment procedures. This study proposes a ... Full text Cite

TH‐C‐201B‐10: Development and Testing of a CT Dose Software “VirtualDose” Using Anatomically Realistic Patient Phantoms: Preliminary Results for the Phase I of the Project

Conference Medical Physics · January 1, 2010 Purpose: To demonstrate the need and feasibility for developing a new software for reporting patient imaging dose who undergoing CT or PET/CT examinations. Method and Materials: Existing CT dose reporting software do not meet the need because of the simpli ... Full text Cite

Training software using virtual-reality technology and pre-calculated effective dose data.

Journal Article Health physics · May 2009 This paper describes the development of a software package, called VR Dose Simulator, which aims to provide interactive radiation safety and ALARA training to radiation workers using virtual-reality (VR) simulations. Combined with a pre-calculated effectiv ... Full text Cite

WE‐E‐BRD‐02: Development of a Software for Integrating the Medical Accelerator Model with Patient Phantoms Into Monte Carlo Based Dosimetry Platform

Conference Medical Physics · January 1, 2009 Purpose: To develop a new software package that integrates the detailed medical accelerator model with anatomically‐realistic phantoms in the Monte Carlo engine, MCNPX, for the determination of secondary organ doses from secondary photons and neutrons duri ... Full text Cite

TU‐C‐304A‐01: The Need and Feasibility of a Modern Software for Reporting Patient Doses From CT Scans

Conference Medical Physics · January 1, 2009 Purpose: To demonstrate the need and feasibility to develop a modern software tool for reporting the organ dose and effective dose for patients undergoing CT examinations. Method and Materials: Existing CT dose reporting software do not meet the need becau ... Full text Cite

Benchmarking of SNAM with the ITER 3D model

Conference Fusion Engineering and Design · October 1, 2007 The discrete ordinates particle transport codes (SN codes) are widely used in reactor design, radiation shielding, nuclear detection and other fields. SN automatic modeling system (SNAM) is an integrated interface program between CAD systems and SN codes, ... Full text Cite

Neutronics analysis for the test blanket modules proposed for EAST and ITER

Journal Article Nuclear Fusion · August 1, 2007 The dual-functional lithium lead-test blanket module (DFLL-TBM) system, which is designated to demonstrate the integrated technologies of both the He single coolant (SLL) blanket and the He-LiPb dual coolant (DLL) blanket, is proposed for testing in ITER t ... Full text Cite

Update of ITER 3D basic neutronics model with MCAM

Conference Fusion Engineering and Design · November 1, 2006 In order to conduct nuclear analyses on neutronics issues for the International Thermonuclear Experimental Reactor (ITER), a standard three-dimensional (3D) neutronics model of the ITER reactor has been developed. However, the model for the Monte Carlo neu ... Full text Cite

Sorption of 243Am(III) to multiwall carbon nanotubes.

Journal Article Environmental science & technology · April 2005 Carbon nanotubes have attracted great interest in multidisciplinary study since their discovery. Herein, radionuclide 243Am(III) sorption to uncapped multiwall carbon nanotubes (MWCNTs) was carried out at 20+/-2 degrees C in 0.01 and 0.1 M NaClO4 solutions ... Full text Cite