Alexandra Stefanovic | Scholars@Duke

Alexandra Stefanovic
Associate Professor of Medicine

I am convinced that caring for patients with malignant hematologic diseases requires not only up-to-date medical knowledge, but also an understanding of the individual patient's needs and circumstances. I encourage patients to take an active role in their treatment and recovery and I work with them to develop an individualized treatment plan that includes the most advanced therapies available today. My practice focuses primarily on disorders of the lymphatic system (Hodgkin and non-Hodgkin lymphoma and chronic lymphocytic leukemia). As an integral part of my clinical activities, I am dedicated to teaching young physicians at all levels of training and educating the next generation of hematologists.

Current Research Interests

My research focuses on lymphomas and related disorders through clinical trials and collaborative research projects. It is my goal to provide patients, whenever possible, access to carefully selected clinical trials with novel therapies that may help them live longer or improve their quality of life.

Current Appointments & Affiliations

Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2018

Contact Information

2400 Pratt St, Suite 9000, Durham, NC 27705
alexandra.stefanovic@duke.edu (919) 684-8964
Duke Health Profile
Duke Medicine Profile

Background
Education, Training, & Certifications
- Fellowship in Hematology/Oncology, Jackson Memorial Hospital, Miami, Florida 2005 - 2008
- Internal Medicine Residency, Western Pennsylvania Hospital 2002 - 2005
- M.D., University of Cologne (Germany 1999
Duke Appointment History
- Instructor in the Department of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2017 - 2018
Academic Positions Outside Duke
- Assistant Professor of Medicine, University of Miami. 2008 - 2017
Expertise
Subject Headings
Global Scholarship
- Expertise
  - Germany (Country)
  - United States of America (Country)
- Research
  - United States of America (Country)
- Teaching
  - United States of America (Country)
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Kelly, KR, Friedberg, JW, Park, SI, McDonagh, K, Hayslip, J, Persky, D, Ruan, J, Puvvada, S, Rosen, P, Iyer, SP, Stefanovic, A, Bernstein, SH, Weitman, S, Karnad, A, Monohan, G, VanderWalde, A, Mena, R, Schmelz, M, Spier, C, Groshen, S, Venkatakrishnan, K, Zhou, X, Sheldon-Waniga, E, Leonard, EJ, and Mahadevan, D. "Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 24, no. 24 (December 2018): 6150-6159. Full Text
  - Alderuccio, JP, Stefanovic, A, Dammrich, D, Chapman, JR, Vega, F, Selvaggi, G, Tzakis, A, and Lossos, IS. "Decreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy." Leukemia & Lymphoma 59, no. 9 (September 2018): 2096-2104. Full Text
  - Dejman, A, Alavi, SN, Thomas, DB, Stefanovic, A, Asif, A, and Nayer, A. "The potential role of complements in cocaine-induced thrombotic microangiopathy." Clinical kidney journal 11, no. 1 (February 2018): 26-28. Full Text
  - Hosein, PJ, Sandoval-Sus, JD, Goodman, D, Arteaga, AG, Reis, I, Hoffman, J, Stefanovic, A, Rosenblatt, JD, and Lossos, IS. "Updated survival analysis of two sequential prospective trials of R-MACLO-IVAM followed by maintenance for newly diagnosed mantle cell lymphoma." American Journal of Hematology 90, no. 6 (June 2015): E111-E116. Full Text
  - Lossos, IS, Fabregas, JC, Koru-Sengul, T, Miao, F, Goodman, D, Serafini, AN, Hosein, PJ, Stefanovic, A, Rosenblatt, JD, and Hoffman, JE. "Phase II study of (90)Y Ibritumomab tiuxetan (Zevalin) in patients with previously untreated marginal zone lymphoma." Leukemia & lymphoma 56, no. 6 (June 2015): 1750-1755. Full Text
  - Talebi, TN, Stefanovic, A, Merchan, J, Lian, E, and Silva, O. "Sunitinib-induced microangiopathic hemolytic anemia with fatal outcome." American Journal of Therapeutics 19, no. 4 (July 2012): e143-e145. Full Text
  - Joo, SH, Acun, Z, Stefanovic, A, Blieden, CR, Ikpatt, OF, and Moon, J. "Post-transplant lymphoproliferative disorder presented as small bowel intussusception in adult liver transplant patient." Journal of the Korean Surgical Society 82, no. 1 (January 2012): 50-53. Full Text Open Access Copy
  - Talebi, T, Fernandez-Castro, G, Montero, AJ, Stefanovic, A, and Lian, E. "A case of severe thrombotic thrombocytopenic purpura with concomitant Legionella pneumonia: review of pathogenesis and treatment." American journal of therapeutics 18, no. 5 (September 2011): e180-e185. Full Text
  - Bayraktar, S, Bayraktar, UD, Ramos, JC, Stefanovic, A, and Lossos, IS. "Primary CNS lymphoma in HIV positive and negative patients: comparison of clinical characteristics, outcome and prognostic factors." Journal of neuro-oncology 101, no. 2 (January 2011): 257-265. Full Text
  - Bayraktar, S, Bayraktar, UD, Stefanovic, A, and Lossos, IS. "Primary ocular adnexal mucosa-associated lymphoid tissue lymphoma (MALT): single institution experience in a large cohort of patients." British journal of haematology 152, no. 1 (January 2011): 72-80. Full Text
  - Hansra, D, Montague, N, Stefanovic, A, Akunyili, I, Harzand, A, Natkunam, Y, de la Ossa, M, Byrne, GE, and Lossos, IS. "Oral and extraoral plasmablastic lymphoma: similarities and differences in clinicopathologic characteristics." American Journal of Clinical Pathology 134, no. 5 (November 2010): 710-719. Full Text
  - Bayraktar, S, Stefanovic, A, Montague, N, Davis, J, Murray, T, and Lossos, IS. "Central nervous system manifestations of marginal zone B-cell lymphoma." Annals of hematology 89, no. 10 (October 2010): 1003-1009. Full Text
  - Stefanovic, A, Davis, J, Murray, T, Markoe, A, and Lossos, IS. "Treatment of isolated primary intraocular lymphoma with high-dose methotrexate-based chemotherapy and binocular radiation therapy: a single-institution experience." British journal of haematology 151, no. 1 (October 2010): 103-106. (Letter) Full Text
  - Stefanovic, A, and Lossos, IS. "Primary testicular lymphoma: the site matters." Leukemia & lymphoma 51, no. 7 (July 2010): 1159-1160. Full Text
  - Stefanovic, A, and Lossos, IS. "Rare PTCLs: treatment lagging behind pathobiologic advances." Oncology (Williston Park, N.Y.) 24, no. 1 (January 2010): 101-102. (Review)
  - Stefanovic, A, and Lossos, IS. "Response: Variability in the prevalence of Chlamydophila psittaci infection in patients with OAML." Blood 114, no. 16 (October 15, 2009): 3499-3500. Full Text
  - Escalón, MP, Stefanovic, A, Venkatraman, A, Pereira, D, Santos, ES, Goodman, M, Byrnes, JJ, and Fernandez, HF. "Autologous transplantation for relapsed non-Hodgkin's lymphoma using intravenous busulfan and cyclophosphamide as conditioning regimen: a single center experience." Bone marrow transplantation 44, no. 2 (July 2009): 89-96. Full Text
  - Stefanovic, A, and Lossos, IS. "Extranodal marginal zone lymphoma of the ocular adnexa." Blood 114, no. 3 (July 2009): 501-510. (Review) Full Text
  - Kalkanis, D, Stefanovic, A, Paes, F, Escalon, MP, Serafini, A, and Lossos, IS. "[18F]-fluorodeoxyglucose positron emission tomography combined with computed tomography detection of asymptomatic late pulmonary toxicity in patients with non-Hodgkin lymphoma treated with rituximab-containing chemotherapy." Leukemia & Lymphoma 50, no. 6 (June 2009): 904-911. Full Text
  - Stefanovic, A, Morgensztern, D, Fong, T, and Lossos, IS. "Pulmonary marginal zone lymphoma: a single centre experience and review of the SEER database." Leukemia & Lymphoma 49, no. 7 (July 2008): 1311-1320. Full Text
  - Baldus, SE, Wickenhauser, C, Dittmar, E, Stefanovic, A, and Thiele, J. "Visualization of carbohydrate-binding molecules expressed by myelomono- and erythropoietic cells derived from human bone marrow: an immunoenzymatic double-staining study." The Histochemical journal 32, no. 1 (January 2000): 27-32. Full Text
  - Baldus, SE, Wickenhauser, C, Stefanovic, A, Schmitz, B, Thiele, J, and Fischer, R. "Enrichment of human bone marrow mononuclear phagocytes and characterization of macrophage subpopulations by immunoenzymatic double staining." The Histochemical journal 30, no. 4 (April 1998): 285-291. Full Text
- Conference Papers
  - Fabregas, JC, Hoffman, JE, Koru-Sengul, T, Feng, M, Goodman, D, Serafini, A, Hosein, PJ, Stefanovic, A, Rosenblatt, JD, and Lossos, IS. "Phase II study of (90)y Ibritumomab Tiuxetan (Zevalin) in Patients with Previously Untreated Marginal Zone Lymphoma." December 6, 2014. Link to Item
  - Deutsch, YE, Dammrich, DJ, Fabregas, JC, Pirnentel, A, Stefanovic, A, and Hoffman, JE. "Clinical Experience Of Lenalidomide Plus Low Dose Dexamethasone As First-Line Therapy For Multiple Myeloma At a Large County Hospital Caring For An Indigent Population." November 15, 2013. Link to Item
  - Kelly, KR, Persky, DO, Mahadevan, D, Miller, TP, Puvvada, SD, McDonagh, K, Hayslip, J, Park, SI, Ruan, J, Rosen, PJ, Iyer, SP, Stefanovic, A, Zhang, B, Zhou, X, Ullmann, CD, Leonard, EJ, and Friedberg, JW. "Phase 1 Study Of Investigational Agent MLN8237 (Alisertib) plus Rituximab +/- Vincristine In Patients (Pts) With Relapsed/Refractory (Rel/Ref) Aggressive B-Cell Lymphomas." November 15, 2013. Link to Item
  - Sandoval-Sus, JD, Hosein, PJ, Goodman, D, Stefanovic, A, Rosenblatt, JD, and Lossos, IS. "Updated Analysis of a Prospective Phase II Trial of R-MACLO-IVAM Followed by Maintenance for Mantle Cell Lymphoma." November 16, 2012. Link to Item
  - Stefanovic, A, Dammrich, D, Tzakis, A, and Lossos, IS. "Post-Transplant Lymphoproliferative Disease In Liver Transplant Recipients: A Single Institution Experience." November 19, 2010. Link to Item
  - Bayraktar, S, Bayraktar, UD, Stefanovic, A, and Lossos, IS. "Primary CNS lymphoma in HIV-positive and -negative patients: Comparison of clinical characteristics, outcome, and prognostic factors." May 20, 2010. Full Text
  - Stefanovic, A, Hansra, DM, Montague, N, Akunyili, I, Harzand, A, Natkunam, Y, de la Ossa, M, Byrne, GE, and Lossos, IS. "Oral and extraoral plasmablastic lymphoma: Similarities and differences in clinicopathological characteristics." May 20, 2010. Full Text
  - Stefanovic, A, Morgensztern, D, Fong, TH, and Lossos, IS. "Pulmonary marginal zone lymphoma: A single center experience and review of the SEER database." May 20, 2008. Full Text

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Education, Training, & Certifications

Duke Appointment History

Academic Positions Outside Duke

Subject Headings

Global Scholarship

Expertise

Research

Teaching

Selected Publications

Academic Articles

Conference Papers