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Alexandra Thomas

Professor of Medicine
Medicine, Medical Oncology
40 Duke Medicine Circle, Clinic 2-2, Durham, NC 27710
40 Duke Medicine Circle, Clinic 2-2, Durham, NC 27710

Current Appointments & Affiliations


Professor of Medicine · 2024 - Present Medicine, Medical Oncology, Medicine
Member of the Duke Cancer Institute · 2024 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published March 10, 2025
Targeted Therapies Improve Outcomes for Some Breast Cancers

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Recent Publications


Climate Therapy: Sustainability Solutions for Breast Cancer Care in the Anthropocene Era.

Journal Article Clin Breast Cancer · April 2025 Climate change is the greatest threat to human existence. Currently it impacts breast cancer care by disrupting treatment, by food poverty and economic hardship and through fossil fuel pollution which increases breast cancer incidence. These impacts are gr ... Full text Link to item Cite

Further Optimizing Care of Patients With Operable Hormone Receptor-Sensitive Breast Cancer.

Journal Article J Clin Oncol · February 10, 2025 Harmonized global collaborations are crucial to improving outcomes in hormone sensitive operable breast cancer. ... Full text Link to item Cite

Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.

Journal Article Ann Oncol · February 2025 BACKGROUND: Hormone receptor-positive (HR+), human epidermal growth factor receptor 2 (HER2)-negative early-stage breast cancer (EBC) is a heterogenous disease. Identification of better clinical and molecular biomarkers is essential to guide optimal therap ... Full text Link to item Cite
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Recent Grants


A single shot therapy will accelerate the elimination of breast cancer

ResearchResearch Professional · Awarded by United States Army Medical Research Acquisition Activity · 2024 - 2028

Cardiovascular Impact of Near-complete Estrogen Deprivation for Breast Cancer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027

NRG ONCOLOGY NETWORK GROUP OPERATIONS CENTER

ResearchPrincipal Investigator · Awarded by NRG Oncology · 2023 - 2025

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Education, Training & Certifications


Johns Hopkins University, School of Medicine · 1995 M.D.