Scholars@Duke
Alireza Ghoreifi

Alireza Ghoreifi

House Staff
Urology

Selected Publications

Can Urinary Diversion Type Affect Postoperative Complications Following Radical Cystectomy in Female Patients?

Journal Article International journal of urology : official journal of the Japanese Urological Association · December 2025 PurposeTo assess the impact of urinary diversion (UD) type on complications following radical cystectomy (RC) in female patients.MethodsWe retrospectively reviewed our RC database for all female RCs between 2003 and 2024. Patients were ca ... Full text Cite

Does Cardiopulmonary Bypass Affect Outcomes in Nephrectomy with Level III/IV Caval Thrombectomy for Renal Cell Carcinoma?

Journal Article Curr Oncol · November 29, 2025 Radical nephrectomy with inferior vena cava (IVC) thrombectomy is a technically complex procedure. Cardiopulmonary bypass (CPB) is frequently employed for managing high-level thrombi, yet its impact on surgical outcomes remains uncertain. This study evalua ... Full text Link to item Cite

Small Renal Mass Cryoablation: Trifecta Outcomes of a Single-Institution Experience with a 20-Year Follow-Up.

Journal Article Cancers (Basel) · September 10, 2025 BACKGROUND/OBJECTIVES: Cryoablation is a minimally invasive treatment option for patients with a small renal mass (SRM). We aimed to present the long-term functional and oncologic outcomes of cryoablation for SRMs. METHODS: We retrospectively reviewed pati ... Full text Link to item Cite

Identifying the best candidate for focal therapy: a comprehensive review.

Journal Article Prostate cancer and prostatic diseases · September 2025 BackgroundDespite the evidence supporting the use of focal therapy (FT) in patients with localized prostate cancer (PCa), considerable variability exists in the patient selection criteria across current studies. This study aims to review the most ... Full text Cite

Comparative Economic Evaluation of Radical Prostatectomy, Radiation, and Ablative Techniques in the Management of Localized Prostate Cancer.

Journal Article Cancers (Basel) · August 28, 2025 Background: To compare the costs of open retropubic radical prostatectomy (RRP), robotic-assisted radical prostatectomy (RALP), intensity-modulated radiation therapy (IMRT), low-dose brachytherapy (LDBT), stereotactic body radiotherapy (SBRT), cryotherapy ... Full text Link to item Cite

Editorial Comment.

Journal Article The Journal of urology · June 2025 Full text Cite

Prognostic Impact of Adjuvant Immunotherapy in Patients with High-Risk Upper Tract Urothelial Cancer: Results from the ROBUUST 2.0 Collaborative Group.

Journal Article Cancers · June 2025 Background/Objective: The impact of adjuvant immunotherapy (IO) on the prognosis of patients with upper tract urothelial carcinoma (UTUC) remains unclear. This study examines the association of adjuvant IO with oncologic outcomes in patients with hi ... Full text Cite

The outcomes of salvage robotic radical prostatectomy following radiation versus focal therapy: Does the primary treatment modality matter?

Journal Article BJUI compass · May 2025 ObjectivesWe aim to compare salvage robotic radical prostatectomy (sRRP) for recurrent prostate cancer (PCa) after primary radiation (RT) versus focal therapy (FT).Materials and methodsPatients who underwent sRRP following primary local t ... Full text Cite

New Insights into Upper Tract Urothelial Carcinoma: Lessons Learned from the ROBUUST Collaborative Study.

Journal Article Cancers · May 2025 Upper tract urothelial carcinoma (UTUC) is a rare malignancy, representing only 5-10% of urothelial carcinoma. The mainstay of treatment for high-risk patients is radical nephroureterectomy. Given the aggressive behavior of this disease, additional treatme ... Full text Cite

Surveillance of non-muscle-invasive bladder cancer with blue-light cystoscopy: a meta-analysis.

Journal Article BJU Int · October 2024 OBJECTIVE: To compare the value of flexible blue-light cystoscopy (BLC) vs flexible white-light cystoscopy (WLC) in the surveillance setting of non-muscle-invasive bladder cancer (NMIBC). METHODS: All major databases were searched for articles published be ... Full text Link to item Cite

Reply by Authors.

Journal Article The Journal of urology · June 2024 Full text Cite

Salvage High-Intensity Focused Ultrasound for Prostate Cancer after Radiation Failure: A Narrative Review.

Journal Article Current oncology (Toronto, Ont.) · June 2024 For patients diagnosed with localized prostate cancer, there are multiple treatment options available. The traditional treatment modalities include radical prostatectomy and radiotherapy. Nevertheless, focal therapy, including high-intensity focused ultras ... Full text Cite

Reply by Authors.

Journal Article The Journal of urology · June 2024 Full text Cite

Prophylactic Use of Biologic Mesh in Ileal Conduit (PUBMIC): A Randomized Clinical Trial.

Journal Article The Journal of urology · June 2024 PurposeWe assessed the effect of prophylactic biologic mesh on parastomal hernia (PSH) development in patients undergoing cystectomy and ileal conduit (IC).Materials and methodsThis phase 3, randomized, controlled trial (NCT02439060) incl ... Full text Cite

Blood-based liquid biopsy: A promising noninvasive test in diagnosis, surveillance, and prognosis of patients with upper tract urothelial carcinoma.

Journal Article Urologic oncology · April 2024 ObjectivesTo assess the efficacy of blood-based liquid biopsy in the diagnosis, surveillance, and prognosis of upper tract urothelial carcinoma (UTUC).Methods and materialsIn this prospective study, peripheral blood samples were collected ... Full text Cite

A Comprehensive Review on Upper Tract Urothelial Carcinoma: An Update in 2023.

Journal Article Cancers · April 2024 It is our pleasure to serve as the guest editors for the Cancers journal for this Special Issue, titled "Comprehensive Review on Upper Tract Urothelial Carcinoma: An Update in 2023" [...]. ... Full text Cite

Racial Differences in the Detection Rate of Bladder Cancer Using Blue Light Cystoscopy: Insights from a Multicenter Registry.

Journal Article Cancers · March 2024 The use of blue light cystoscopy (BLC) has been shown to improve bladder tumor detection. However, data demonstrating the efficacy of BLC across different races are limited. Herein, we aim to evaluate heterogeneity in the characteristics of BLC for the det ... Full text Cite

Impact of Variant Histology on Oncological Outcomes in Upper Tract Urothelial Carcinoma: Results From the ROBUUST Collaborative Group.

Journal Article Clinical genitourinary cancer · October 2023 IntroductionOncologic implications of variant histology (VH) have been extensively studied in bladder cancer; however, further investigation is needed in upper tract urothelial carcinoma (UTUC). Our study aims to evaluate the impact of VH on oncol ... Full text Cite

Modern Kidney-Sparing Management of Upper Tract Urothelial Carcinoma.

Journal Article Cancers · September 2023 PurposeTo review the latest evidence on the modern techniques and outcomes of kidney-sparing surgeries (KSS) in patients with upper tract urothelial carcinoma (UTUC).MethodsA comprehensive literature search on the study topic was conducte ... Full text Cite

Perioperative mortality for radical cystectomy in the modern Era: experience from a tertiary referral center.

Journal Article International braz j urol : official journal of the Brazilian Society of Urology · May 2023 PurposeTo evaluate the perioperative mortality and contributing variables among patients who underwent radical cystectomy (RC) for bladder cancer in recent decades, with comparison between modern (after 2010) and premodern (before 2010) eras.M ... Full text Cite

A Urine-based DNA Methylation Marker Test to Detect Upper Tract Urothelial Carcinoma: A Prospective Cohort Study.

Journal Article The Journal of urology · May 2023 PurposeWe explored the accuracy of a urine-based epigenetic test for detecting upper tract urothelial carcinoma.Materials and methodsUnder an Institutional Review Board-approved protocol, urine samples were prospectively collected from pr ... Full text Cite

Reply by Authors.

Journal Article The Journal of urology · May 2023 Full text Cite

Robotic post-chemotherapy retroperitoneal lymph node dissection for testicular cancer: A multicenter collaborative study.

Journal Article Urologic oncology · February 2023 ObjectivesTo evaluate the perioperative and oncological/functional outcomes of robotic post-chemotherapy retroperitoneal lymph node dissection for testicular cancer.Methods and materialsIn this retrospective study, we included patients wh ... Full text Cite

Comparing Oncological and Perioperative Outcomes of Open versus Laparoscopic versus Robotic Radical Nephroureterectomy for the Treatment of Upper Tract Urothelial Carcinoma: A Multicenter, Multinational, Propensity Score-Matched Analysis.

Journal Article Cancers · February 2023 ObjectivesTo identify correlates of survival and perioperative outcomes of upper tract urothelial carcinoma (UTUC) patients undergoing open (ORNU), laparoscopic (LRNU), and robotic (RRNU) radical nephroureterectomy (RNU).MethodsWe conduct ... Full text Cite

Therapeutic Effects of Low-Level Laser on Male Infertility: A Systematic Review.

Journal Article Journal of lasers in medical sciences · January 2023 Introduction: The objective of this study was to assess the effectiveness and safety of photobiomodulation (PBM) in the treatment of male infertility. Methods: We searched Google Scholar, PubMed, and the reference sections of relevant papers ... Full text Cite

Biological and prognostic implications of biopsy upgrading for high-grade upper tract urothelial carcinoma at nephroureterectomy.

Journal Article International journal of urology : official journal of the Japanese Urological Association · January 2023 ObjectivesTechnical limitations of ureteroscopic (URS) biopsy has been considered responsible for substantial upgrading rate in upper tract urothelial carcinoma (UTUC). However, the impact of tumor specific factors for upgrading remain uninvestiga ... Full text Cite

Risk factors and natural history of parastomal hernia after radical cystectomy and ileal conduit.

Journal Article BJU international · September 2022 ObjectiveTo investigate the incidence, risk factors and natural history of parastomal hernia (PSH).Materials and methodsWe reviewed the records of patients who underwent radical cystectomy (RC) and ileal conduit (IC) procedure between 200 ... Full text Cite

Long-term renal function in patients with chronic kidney disease following radical cystectomy and orthotopic neobladder.

Journal Article BJU international · August 2022 ObjectiveTo evaluate long-term renal function in patients with chronic kidney disease (CKD) Stage IIIa who underwent radical cystectomy and orthotopic neobladder (RC/ONB) compared to matched controls.Patients and methodsUsing our Institut ... Full text Cite

Liquid Biopsy Landscape in Patients with Primary Upper Tract Urothelial Carcinoma.

Journal Article Cancers · June 2022 Urothelial carcinomas (UCs) are a broad and heterogeneous group of malignancies, with the prevalence of upper tract urothelial carcinoma (UTUC) being rare, accounting for only 5-10% of total malignancies. There is a need for additional toolsets to assist t ... Full text Cite

Single-stage Xi® robotic radical nephroureterectomy for upper tract urothelial carcinoma: surgical technique and outcomes.

Journal Article Minerva urology and nephrology · April 2022 BackgroundRadical nephroureterectomy (RNU) represents the standard of care for high grade upper tract urothelial carcinoma (UTUC). Open and laparoscopic approaches are well-established treatments, but evidence regarding robotic RNU is growing. The ... Full text Cite

Pentafecta for Radical Nephroureterectomy in Patients with High-Risk Upper Tract Urothelial Carcinoma: A Proposal for Standardization of Quality Care Metrics.

Journal Article Cancers · March 2022 Background: Measuring quality of care indicators is important for clinicians and decision making in health care to improve patient outcomes. Objective: The primary objective was to identify quality of care indicators for patients with upper tract urothelia ... Full text Cite

Bladder Recurrence Following Diagnostic Ureteroscopy in Patients Undergoing Nephroureterectomy for Upper Tract Urothelial Cancer: Is Ureteral Access Sheath Protective?

Journal Article Urology · February 2022 ObjectiveTo examine the effect of diagnostic ureteroscopy (URS) and ureteral access sheath usage on bladder recurrence following radical nephroureterectomy (RNU).MethodsWe retrospectively reviewed the records of patients who underwent RNU ... Full text Cite

A Preoperative Nomogram to Predict Renal Function Insufficiency for Cisplatin-based Adjuvant Chemotherapy Following Minimally Invasive Radical Nephroureterectomy (ROBUUST Collaborative Group).

Journal Article European urology focus · January 2022 BackgroundPostoperative renal function impairment represents a main limitation for delivering adjuvant chemotherapy after radical nephroureterectomy (RNU).ObjectiveTo create a model predicting renal function decline after minimally invasi ... Full text Cite

Enhanced recovery after cystectomy in patients with preoperative narcotic use.

Journal Article Canadian Urological Association journal = Journal de l'Association des urologues du Canada · October 2021 IntroductionThe aim of this study was to evaluate the outcomes of radical cystectomy with an enhanced recovery after surgery (ERAS) protocol in patients with a history of chronic preoperative narcotic use compared to narcotic-naive patients.Me ... Full text Cite

Risk Factors for Intravesical Recurrence after Minimally Invasive Nephroureterectomy for Upper Tract Urothelial Cancer (ROBUUST Collaboration).

Journal Article The Journal of urology · September 2021 PurposeIntravesical recurrence (IVR) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) has an incidence of approximately 20%-50%. Studies to date have been composed of mixed treatment cohorts-open, laparoscopic and ... Full text Cite

Quality assessment of case reports in high-impact urology journals using SCARE guideline.

Journal Article Health science reports · September 2021 Background and aimsThe usefulness of case reports is dependent on the complete, consistent, and rigorous reporting of these cases. In order to provide a standard guideline for reporting surgical case reports, the SCARE (Surgical CAse REport) guide ... Full text Cite

Development and validation of an objective scoring tool to evaluate surgical dissection: Dissection Assessment for Robotic Technique (DART).

Journal Article Urology practice · September 2021 PurposeEvaluation of surgical competency has important implications for training new surgeons, accreditation, and improving patient outcomes. A method to specifically evaluate dissection performance does not yet exist. This project aimed to design ... Full text Cite

Perioperative outcomes of goal-directed versus conventional fluid therapy in radical cystectomy with enhanced recovery protocol.

Journal Article International urology and nephrology · September 2021 PurposeThe aim of this study is to evaluate the intra/perioperative fluid management and early postoperative outcomes of patients who underwent radical cystectomy with Enhanced Recovery After Surgery protocol, using goal-directed fluid therapy com ... Full text Cite

Reply by Authors.

Journal Article Urology practice · September 2021 Full text Cite

Stoma complications and quality of life in patients with Indiana pouch versus appendico/neo-appendico-umbilicostomy urinary diversions.

Journal Article World J Urol · May 2021 OBJECTIVES: To evaluate three subtypes of continent-cutaneous urinary diversion (CCUD); Indiana pouch (IP), right colon pouch with appendico-umbilicostomy (AU), and right colon pouch with neo-appendico-umbilicostomy (NAU), by investigating diversion-specif ... Full text Link to item Cite

Surgical Tips for Inferior Vena Cava Thrombectomy.

Journal Article Current urology reports · October 2020 Purpose of reviewThe aim of this review is to describe the preoperative evaluation, surgical techniques, and postoperative management of patients with renal cell carcinoma (RCC) undergoing radical nephrectomy (RN) and inferior vena cava (IVC) thro ... Full text Cite

Perioperative complications and oncological outcomes following radical cystectomy among different racial groups: A long-term, single-center study.

Journal Article Canadian Urological Association journal = Journal de l'Association des urologues du Canada · October 2020 IntroductionCurrent literature on perioperative and oncological outcomes following radical cystectomy among different racial groups is limited, especially among Hispanics and Asians. The objective of this study was to assess the impact of racial d ... Full text Cite

Natural History of Radiologic Incisional Hernia Following Robotic Nephrectomy.

Journal Article Journal of endourology · September 2020 Objective: To evaluate the incidence and natural history of radiologic incisional hernia (IH) in patients who underwent robotic partial or radical nephrectomy. Materials and Methods: We retrospectively reviewed the records of pa ... Full text Cite

Perioperative Outcome of Suprarenal Resection of Vena Cava Without Reconstruction in Urologic Malignancies: A Case Series and Review of the Literature.

Journal Article Urology · August 2020 ObjectiveTo describe the feasibility and perioperative outcome of suprarenal resection of inferior vena cava (IVC) in urologic neoplasms without reconstruction.MethodsWe retrospectively reviewed the patients who underwent suprarenal resec ... Full text Cite

Testicular Carcinoid Tumor in a Patient With Contralateral Classic Seminoma.

Journal Article Urology · July 2020 Testicular neuroendocrine tumors, commonly called carcinoid, are extremely rare and account for less than 1% of all testicular neoplasms. The most common type is primary carcinoid followed by testicular metastasis from another primary and rarely carcinoid ... Full text Cite

Urinary tract infections following radical cystectomy with enhanced recovery protocol: A prospective study.

Journal Article Urologic oncology · March 2020 ObjectivesUrinary tract infection (UTI) following radical cystectomy (RC) is a common complication associated with significant morbidity and risk of readmission. Recent literature has assessed the effect of perioperative antibiotic regimens on the ... Full text Cite

Management of Primary Testicular Tumor.

Journal Article The Urologic clinics of North America · August 2019 In any man with a solid testicular mass, cancer should be considered until proven otherwise. Radical inguinal orchiectomy is the treatment of choice in patients with testis mass. Placement of a testicular prosthesis is safe with a very low complication rat ... Full text Cite

Immediate Vascular Complications After Kidney Transplant: Experience from 2100 Recipients.

Journal Article Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation · October 2017 ObjectivesVascular complications, especially immediate events during kidney transplant, are the major cause of graft loss, and prompt surgical intervention is important for salvage of the graft and recipient. In this study, our aim was to show our ... Full text Cite

Penile metastasis originating from prostate adenocarcinoma: An unusual presentation with penile curvature

Journal Article Nephro Urology Monthly · January 1, 2017 Despite the high rate of prostate cancer, the incidence of penile metastasis originating from prostate cancer is extremely rare, especially in the form of Peyronie’s disease. Moreover, brain metastasis, which is caused by prostate cancer, is not a common p ... Full text Cite

Metabolic syndrome in patients with prostate cancer undergoing intermittent androgen-deprivation therapy.

Journal Article Canadian Urological Association journal = Journal de l'Association des urologues du Canada · September 2016 IntroductionThe presence of metabolic syndrome in men with prostate cancer (PCa) undergoing androgen-deprivation therapy (ADT), especially intermittent type, has not been completely evaluated. The aim of this study is to evaluate metabolic syndrom ... Full text Cite

Nonocclusive mesenteric ischemia after renal transplantation: A case report and literature review.

Journal Article Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia · May 2016 Nonocclusive mesenteric ischemia (NOMI) is a very rare occurrence after renal transplantation. This disorder is difficult to diagnose and can even be fatal. We describe a 51- year-old man with end-stage renal disease who developed intestinal ischemia and i ... Full text Cite

Fold-back perineoscrotal flap plus penile inversion vaginoplasty for male-to-female gender reassignment surgery in circumcised subjects

Journal Article European Journal of Plastic Surgery · February 1, 2015 Background: The use of the penile skin for vaginoplasty is a common method in male-to-female (MTF) transsexual surgery. We aim to describe the results of a one-stage vaginoplasty in previously circumcised sex reassignment surgery using fold-back perineoscr ... Full text Cite

Inflammatory myofibroblastic tumour in a female urethra: A rare benign lesion that mimics malignancy.

Journal Article Canadian Urological Association journal = Journal de l'Association des urologues du Canada · November 2014 Inflammatory myofibroblastic tumour (IMT) is a rare spindle tumour that mimics malignant processes. It can affect any part of the body, but rarely occurs in the genitourinary tract. We report a case of urethral IMT in a 31-year-old female. The diagnosis wa ... Full text Cite

Minimally invasive procedures for treatment of urolithiasis in transplanted kidneys.

Journal Article Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation · June 2014 ObjectivesTo assess the safety and efficacy of minimally invasive procedures for urolithiasis in transplanted kidneys.Materials and methodsA retrospective study was done on kidney transplant patients who had urolithiasis treated with mini ... Full text Cite

Pulmonary and chest wall metastasectomy in urogenital tumors: a single center experience and review of literature.

Journal Article Nephro-urology monthly · May 2014 BackgroundPulmonary metastases are often found in advanced malignancies. Urogenital malignancies originating from kidney, prostate, testes, and bladder all metastasize preferentially to the lungs.ObjectivesThis retrospective study aimed t ... Full text Cite

Recurrent Spontaneous Rupture of the Urinary Bladder in a Patient With Human T-lymphotropic Virus Type 1-Associated Myelopathy: A Case Report and Literature Review.

Journal Article Nephro-urology monthly · March 2014 Recurrent spontaneous rupture of the urinary bladder has rarely been reported in English articles. This condition may be difficult to diagnosis before a laparotomy due to acute peritonitis. Herein we describe a case of recurrent spontaneous rupture of the ... Full text Cite

Effect of kidney transplantation on early and late post-transplant prostate-specific antigen levels.

Journal Article Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia · March 2014 The aim of this study was to determine the effect of kidney transplantation on serum prostate-specific antigen (PSA) levels. Forty patients who were on peritoneal dialysis or hemodialysis underwent kidney transplantation at our department. The immunosuppre ... Full text Cite

Dorsally Placed Buccal Mucosal Graft Urethroplasty in Treatment of Long Urethral Strictures Using One-Stage Transperineal Approach.

Journal Article International scholarly research notices · January 2014 Objectives. To evaluate the results of one-stage buccal mucosal urethroplasty in treatment of long urethral strictures. Methods. This retrospective study was carried out on 117 patients with long urethral strictures who underwent one-stage transperineal ur ... Full text Cite

Large vaginal and bladder calculi in a woman with previous operation of bladder exstrophy: a case report.

Journal Article Nephro-urology monthly · January 2014 This is to report the case of a huge vaginal stone, and bladder calculi in a 26-year-old woman with previous operation of bladder exstrophy. It seems that the vaginal stone was secondary to the remaining wire used in her previous reconstructive surgery for ... Full text Cite

S227 Ureteroscopy and tranureteral lithotripsy in pregnancy, is it safe?

Journal Article European Urology Supplements · October 2013 Full text Cite

S231 Percutaneous nephrolithotripsy (PCNL) in children

Journal Article European Urology Supplements · October 2013 Full text Cite

A novel method for iatrogenic vesicovaginal fistula treatment: autologous platelet rich plasma injection and platelet rich fibrin glue interposition.

Journal Article The Journal of urology · June 2013 PurposeVesicovaginal fistula remains a challenge in surgical therapy. In this study autologous platelet rich plasma and platelet rich fibrin glue were used as a minimally invasive approach for vesicovaginal fistula closure.Materials and method ... Full text Cite