Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Yale University School of Medicine 1999
  • Ph.D., Yale University 1999
• 

  Duke Appointment History

  • Associate Director of the Center for Cognitive Neuroscience, Center for Cognitive Neuroscience, Duke Institute for Brain Sciences 2015 - 2018
  • Assistant Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Translational Neuroscience, Psychiatry & Behavioral Sciences 2007 - 2017
  • Assistant Professor of Neurobiology, Neurobiology, Basic Science Departments 2008 - 2017
  • Assistant Professor in the Department of Psychology & Neuroscience, Psychology and Neuroscience, Trinity College of Arts & Sciences 2011 - 2017
• Recognition
• 

  In the News

  • AUG 17, 2018

    Duke Institute for Brain Sciences

    Adcock to Direct Center for Cognitive Neuroscience

  • MAR 4, 2016

    NPR

    Could you hack your brain to get more motivated?

  • MAR 2, 2016

    Self-Motivation Can Help Tune Your Brain

  • JUN 26, 2015

    Allen Song Named Interim Director of Brain Institute

  • OCT 29, 2013

    WUNC Radio

    How a sugar pill can treat mental illness
• 

  Awards & Honors

  • Sloan Research Fellowship-Neuroscience. Alfred P. Sloan Foundation. 2008
• Research
• 

  Selected Grants

  • Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
  • Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
  • Targeting reward dysfunction as a mechanism to improve smoking cessation awarded by National Institutes of Health 2016 - 2021
  • Modeling the Neurobehavioral Basis of Extrinsic and Volitional Motivation in ADHD awarded by National Institutes of Health 2017 - 2020
  • Environment Cue-Reactivity: Brain, Behavior and Clinical Outcomes in Tobacco Use awarded by National Institutes of Health 2014 - 2020
  • Increasing Motivation in ADHD Via Self-activation of VTA awarded by National Institutes of Health 2016 - 2020
  • Characterizing Neural Mechanisms of Cognitive Control awarded by National Institutes of Health 2010 - 2019
  • Instructed Activation of the Human Dopaminergic Midbrain Using Real-Time fMRI in Nicotine-Dependent Individuals awarded by Brain and Behavior Research Foundation 2016 - 2019
  • Smoking/Nicotine Dependence in Attention Deficit Hyperactivity Disorder (ADHD) awarded by National Institutes of Health 2017 - 2019
  • Basic predoctoral training in neuroscience awarded by National Institutes of Health 1992 - 2018
  • Connectivity of the Dopaminergic Midbrain During Learned Regulation of Intrinsic Motivation awarded by Canadian Institutes of Health Research 2014 - 2017
  • BRAIN EAGER: Bayesian Models of Translational Neural Networks: Motivation and Reward awarded by  National Science Foundation 2014 - 2017
  • Acute and chronic nicotine modulation of reinforcement learning awarded by National Institutes of Health 2013 - 2017
  • A Compute Cluster for Brain Imaging and Analysis awarded by National Institutes of Health 2016 - 2017
  • Motivated Memory as Therapeutic Target awarded by National Institutes of Health 2011 - 2017
  • Instructed Activation of the Human Dopaminergic Midbrain using Real-Time fMRI awarded by National Institutes of Health 2014 - 2016
  • Training in Fundamental &Translational Neuroscience awarded by National Institutes of Health 2005 - 2016
  • Brain Imaging Studies of Negative Reinforcement in Humans awarded by National Institutes of Health 2009 - 2015
  • From Phenotype to Mechanism: Mapping the Pathways underlying Risky Choice awarded by National Institutes of Health 2009 - 2011
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Wang, Chenhao, Jimmy Lee, New Fei Ho, Joseph K. W. Lim, Joann S. Poh, Gurpreet Rekhi, Ranga Krishnan, et al. “Large-Scale Network Topology Reveals Heterogeneity in Individuals With at Risk Mental State for Psychosis: Findings From the Longitudinal Youth-at-Risk Study..” Cerebral Cortex (New York, N.Y. : 1991) 28, no. 12 (December 2018): 4234–43. https://doi.org/10.1093/cercor/bhx278.
       Full Text
    • Chiew, Kimberly S., Jordan Hashemi, Lee K. Gans, Laura Lerebours, Nathaniel J. Clement, Mai-Anh T. Vu, Guillermo Sapiro, Nicole E. Heller, and R Alison Adcock. “Motivational valence alters memory formation without altering exploration of a real-life spatial environment..” Plos One 13, no. 3 (January 2018). https://doi.org/10.1371/journal.pone.0193506.
       Full Text
    • MacDuffie, Katherine E., Jeff MacInnes, Kathryn C. Dickerson, Kari M. Eddington, Timothy J. Strauman, and R Alison Adcock. “Single session real-time fMRI neurofeedback has a lasting impact on cognitive behavioral therapy strategies..” Neuroimage. Clinical 19 (January 2018): 868–75. https://doi.org/10.1016/j.nicl.2018.06.009.
       Full Text
    • Scult, Matthew A., Annchen R. Knodt, Jamie L. Hanson, Minyoung Ryoo, R Alison Adcock, Ahmad R. Hariri, and Timothy J. Strauman. “Individual differences in regulatory focus predict neural response to reward..” Social Neuroscience 12, no. 4 (August 2017): 419–29. https://doi.org/10.1080/17470919.2016.1178170.
       Full Text  Open Access Copy
    • Murty, Vishnu P., Ian C. Ballard, and R Alison Adcock. “Hippocampus and Prefrontal Cortex Predict Distinct Timescales of Activation in the Human Ventral Tegmental Area..” Cerebral Cortex (New York, N.Y. : 1991) 27, no. 2 (February 2017): 1660–69. https://doi.org/10.1093/cercor/bhw005.
       Full Text
    • Murty, Vishnu P., Alexa Tompary, R Alison Adcock, and Lila Davachi. “Selectivity in Postencoding Connectivity with High-Level Visual Cortex Is Associated with Reward-Motivated Memory..” The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 37, no. 3 (January 2017): 537–45. https://doi.org/10.1523/JNEUROSCI.4032-15.2016.
       Full Text
    • Murty, Vishnu P., Alexa Tompary, R Alison Adcock, and Lila Davachi. “Selectivity in post-encoding connectivity with high-level visual cortex is associated with reward-motivated memory..” The Journal of Neuroscience, December 5, 2016.
    • Murty, Vishnu P., Kevin S. LaBar, and R Alison Adcock. “Distinct medial temporal networks encode surprise during motivation by reward versus punishment..” Neurobiology of Learning and Memory 134 Pt A (October 2016): 55–64. https://doi.org/10.1016/j.nlm.2016.01.018.
       Full Text
    • Wang, C., F. Ji, Z. Hong, J. S. Poh, R. Krishnan, J. Lee, G. Rekhi, et al. “Disrupted salience network functional connectivity and white-matter microstructure in persons at risk for psychosis: findings from the LYRIKS study..” Psychological Medicine 46, no. 13 (October 2016): 2771–83. https://doi.org/10.1017/S0033291716001410.
       Full Text
    • MacInnes, Jeff J., Kathryn C. Dickerson, Nan-Kuei Chen, and R Alison Adcock. “Cognitive Neurostimulation: Learning to Volitionally Sustain Ventral Tegmental Area Activation..” Neuron 89, no. 6 (March 3, 2016): 1331–42. https://doi.org/10.1016/j.neuron.2016.02.002.
       Full Text
    • McClernon, F Joseph, Cynthia A. Conklin, Rachel V. Kozink, R Alison Adcock, Maggie M. Sweitzer, Merideth A. Addicott, Ying-hui Chou, Nan-kuei Chen, Matthew B. Hallyburton, and Anthony M. DeVito. “Hippocampal and Insular Response to Smoking-Related Environments: Neuroimaging Evidence for Drug-Context Effects in Nicotine Dependence..” Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 41, no. 3 (February 2016): 877–85. https://doi.org/10.1038/npp.2015.214.
       Full Text
    • Chiew, Kimberly S., Jessica K. Stanek, and R Alison Adcock. “Reward Anticipation Dynamics during Cognitive Control and Episodic Encoding: Implications for Dopamine..” Front Hum Neurosci 10 (2016). https://doi.org/10.3389/fnhum.2016.00555.
       Full Text  Link to Item
    • Klauser, Paul, Juan Zhou, Joseph K. W. Lim, Joann S. Poh, Hui Zheng, Han Ying Tng, Ranga Krishnan, et al. “Lack of Evidence for Regional Brain Volume or Cortical Thickness Abnormalities in Youths at Clinical High Risk for Psychosis: Findings From the Longitudinal Youth at Risk Study..” Schizophrenia Bulletin 41, no. 6 (November 2015): 1285–93. https://doi.org/10.1093/schbul/sbv012.
       Full Text
    • Murty, Vishnu P., Maheen Shermohammed, David V. Smith, R McKell Carter, Scott A. Huettel, and R Alison Adcock. “Resting state networks distinguish human ventral tegmental area from substantia nigra..” Neuroimage 100 (October 15, 2014): 580–89. https://doi.org/10.1016/j.neuroimage.2014.06.047.
       Full Text  Link to Item
    • Murty, Vishnu P., and R Alison Adcock. “Enriched encoding: reward motivation organizes cortical networks for hippocampal detection of unexpected events..” Cereb Cortex 24, no. 8 (August 2014): 2160–68. https://doi.org/10.1093/cercor/bht063.
       Full Text  Link to Item
    • Kollins, S. H., and R. A. Adcock. “ADHD, altered dopamine neurotransmission, and disrupted reinforcement processes: Implications for smoking and nicotine dependence.” Progress in Neuro Psychopharmacology and Biological Psychiatry 52 (July 3, 2014): 70–78. https://doi.org/10.1016/j.pnpbp.2014.02.002.
       Full Text
    • Dandash, Orwa, Alex Fornito, Jimmy Lee, Richard S. E. Keefe, Michael W. L. Chee, R Alison Adcock, Christos Pantelis, Stephen J. Wood, and Ben J. Harrison. “Altered striatal functional connectivity in subjects with an at-risk mental state for psychosis..” Schizophrenia Bulletin 40, no. 4 (July 2014): 904–13. https://doi.org/10.1093/schbul/sbt093.
       Full Text
    • Kollins, Scott H., and R Alison Adcock. “ADHD, altered dopamine neurotransmission, and disrupted reinforcement processes: implications for smoking and nicotine dependence..” Progress in Neuro Psychopharmacology & Biological Psychiatry 52 (July 2014): 70–78. https://doi.org/10.1016/j.pnpbp.2014.02.002.
       Full Text
    • Braver, Todd S., Marie K. Krug, Kimberly S. Chiew, Wouter Kool, J Andrew Westbrook, Nathan J. Clement, R Alison Adcock, et al. “Mechanisms of motivation-cognition interaction: challenges and opportunities..” Cognitive, Affective & Behavioral Neuroscience 14, no. 2 (June 2014): 443–72. https://doi.org/10.3758/s13415-014-0300-0.
       Full Text
    • Clark, Kait, Matthew S. Cain, R Alison Adcock, and Stephen R. Mitroff. “Context matters: the structure of task goals affects accuracy in multiple-target visual search..” Applied Ergonomics 45, no. 3 (May 2014): 528–33. https://doi.org/10.1016/j.apergo.2013.07.008.
       Full Text
    • Braver, T. S., M. K. Krug, K. S. Chiew, W. Kool, J. A. Westbrook, N. J. Clement, R. A. Adcock, et al. “Mechanisms of motivation-cognition interaction: Challenges and opportunities.” Cognitive, Affective and Behavioral Neuroscience 14, no. 2 (2014): 443–72. https://doi.org/10.3758/s13415-014-0300-0.
       Full Text
    • Clark, K., M. S. Cain, R. A. Adcock, and S. R. Mitroff. “Context matters: The structure of task goals affects accuracy in multiple-target visual search.” Applied Ergonomics 45, no. 3 (January 1, 2014): 528–33. https://doi.org/10.1016/j.apergo.2013.07.008.
       Full Text
    • Yaakub, Siti N., Kavitha Dorairaj, Joann S. Poh, Christopher L. Asplund, Ranga Krishnan, Jimmy Lee, Richard S. E. Keefe, R Alison Adcock, Stephen J. Wood, and Michael W. L. Chee. “Preserved working memory and altered brain activation in persons at risk for psychosis..” The American Journal of Psychiatry 170, no. 11 (November 2013): 1297–1307. https://doi.org/10.1176/appi.ajp.2013.12081135.
       Full Text
    • Libertus, Klaus, Jennifer Gibson, Nadia Z. Hidayatallah, Jane Hirtle, R Alison Adcock, and Amy Needham. “Size matters: how age and reaching experiences shape infants' preferences for different sized objects..” Infant Behavior & Development 36, no. 2 (April 2013): 189–98. https://doi.org/10.1016/j.infbeh.2013.01.006.
       Full Text
    • Murty, Vishnu P., Ian C. Ballard, Katherine E. Macduffie, Ruth M. Krebs, and R Alison Adcock. “Hippocampal networks habituate as novelty accumulates..” Learning & Memory (Cold Spring Harbor, N.Y.) 20, no. 4 (March 19, 2013): 229–35. https://doi.org/10.1101/lm.029728.112.
       Full Text
    • Murty, Vishnu P., Kevin S. Labar, and R Alison Adcock. “Threat of punishment motivates memory encoding via amygdala, not midbrain, interactions with the medial temporal lobe..” The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 32, no. 26 (June 2012): 8969–76. https://doi.org/10.1523/JNEUROSCI.0094-12.2012.
       Full Text
    • Ballard, Ian C., Vishnu P. Murty, R McKell Carter, Jeffrey J. MacInnes, Scott A. Huettel, and R Alison Adcock. “Dorsolateral prefrontal cortex drives mesolimbic dopaminergic regions to initiate motivated behavior..” The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 31, no. 28 (July 2011): 10340–46. https://doi.org/10.1523/JNEUROSCI.0895-11.2011.
       Full Text
    • Whitford, T. J., D. H. Mathalon, M. E. Shenton, B. J. Roach, R. Bammer, R. A. Adcock, S. Bouix, et al. “Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia..” Psychological Medicine 41, no. 5 (May 2011): 959–69. https://doi.org/10.1017/S0033291710001376.
       Full Text
    • Murty, Vishnu P., Maureen Ritchey, R Alison Adcock, and Kevin S. LaBar. “Reprint of: fMRI studies of successful emotional memory encoding: a quantitative meta-analysis..” Neuropsychologia 49, no. 4 (March 2011): 695–705. https://doi.org/10.1016/j.neuropsychologia.2011.02.031.
       Full Text
    • Murty, Vishnu P., Kevin S. LaBar, Derek A. Hamilton, and R Alison Adcock. “Is all motivation good for learning? Dissociable influences of approach and avoidance motivation in declarative memory..” Learn Mem 18, no. 11 (2011): 712–17. https://doi.org/10.1101/lm.023549.111.
       Full Text  Link to Item
    • Murty, Vishnu P., Maureen Ritchey, R Alison Adcock, and Kevin S. LaBar. “fMRI studies of successful emotional memory encoding: A quantitative meta-analysis..” Neuropsychologia 48, no. 12 (October 2010): 3459–69. https://doi.org/10.1016/j.neuropsychologia.2010.07.030.
       Full Text  Link to Item
    • Shohamy, Daphna, and R Alison Adcock. “Dopamine and adaptive memory..” Trends Cogn Sci 14, no. 10 (October 2010): 464–72. https://doi.org/10.1016/j.tics.2010.08.002.
       Full Text  Link to Item
    • Han, Sanghoon, Scott A. Huettel, Ana Raposo, R Alison Adcock, and Ian G. Dobbins. “Functional significance of striatal responses during episodic decisions: recovery or goal attainment?.” The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 30, no. 13 (March 2010): 4767–75. https://doi.org/10.1523/JNEUROSCI.3077-09.2010.
       Full Text
    • Dale, Corby L., Anne M. Findlay, R Alison Adcock, Mary Vertinski, Melissa Fisher, Alexander Genevsky, Stephanie Aldebot, et al. “Timing is everything: neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects..” International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology 75, no. 2 (February 2010): 183–93. https://doi.org/10.1016/j.ijpsycho.2009.10.009.
       Full Text
    • Adcock, R Alison, Corby Dale, Melissa Fisher, Stephanie Aldebot, Alexander Genevsky, Gregory V. Simpson, Srikantan Nagarajan, and Sophia Vinogradov. “When top-down meets bottom-up: auditory training enhances verbal memory in schizophrenia..” Schizophrenia Bulletin 35, no. 6 (November 2009): 1132–41. https://doi.org/10.1093/schbul/sbp068.
       Full Text
    • Carter, R McKell, Jeff J. Macinnes, Scott A. Huettel, and R Alison Adcock. “Activation in the VTA and nucleus accumbens increases in anticipation of both gains and losses..” Frontiers in Behavioral Neuroscience 3 (January 2009). https://doi.org/10.3389/neuro.08.021.2009.
       Full Text
    • Adcock, R Alison, Arul Thangavel, Susan Whitfield-Gabrieli, Brian Knutson, and John D. E. Gabrieli. “Reward-motivated learning: mesolimbic activation precedes memory formation..” Neuron 50, no. 3 (May 2006): 507–17. https://doi.org/10.1016/j.neuron.2006.03.036.
       Full Text
    • Knutson, Brian, and R Alison Adcock. “Remembrance of rewards past..” Neuron 45, no. 3 (February 2005): 331–32. https://doi.org/10.1016/j.neuron.2005.01.020.
       Full Text
    • Adcock, R. A., R. T. Constable, J. C. Gore, and P. S. Goldman-Rakic. “Functional neuroanatomy of executive processes involved in dual-task performance..” Proceedings of the National Academy of Sciences of the United States of America 97, no. 7 (March 2000): 3567–72. https://doi.org/10.1073/pnas.060588897.
       Full Text
    • Lane, J. D., R. A. Adcock, and R. E. Burnett. “Respiratory sinus arrhythmia and cardiovascular responses to stress..” Psychophysiology 29, no. 4 (July 1992): 461–70. https://doi.org/10.1111/j.1469-8986.1992.tb01720.x.
       Full Text
    • Lane, J. D., R. A. Adcock, R. B. Williams, and C. M. Kuhn. “Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption..” Psychosomatic Medicine 52, no. 3 (May 1990): 320–36. https://doi.org/10.1097/00006842-199005000-00006.
       Full Text

  • Book Sections

    • Murty, V. P., and R. A. Adcock. “Distinct medial temporal lobe network states as neural contexts for motivated memory formation.” In The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition, 467–501, 2017. https://doi.org/10.1007/978-3-319-50406-3_15.
       Full Text

  • Conference Papers

    • Clement, Nathan, and R Alison Adcock. “MOVE FASTER TO LEARN BETTER: EXPLORATION SPEED IMPACTS LEARNING ABOUT OBJECTS AND THEIR LOCATIONS.” In Journal of Cognitive Neuroscience, 79–80. MIT PRESS, 2013.
       Link to Item
    • Murty, Vishnu, Kevin LaBar, and R Alison Adcock. “THE ACTIVE AVOIDANCE OF THREAT ENHANCES NEURAL SENSITIVITY TO EXPECTANCY VIOLATION..” In Journal of Cognitive Neuroscience, 183–183. MIT PRESS, 2013.
       Link to Item
    • Sumner, Elizabeth, Kristin Duffy, and R Alison Adcock. “DOPAMINERGIC MODULATION OF REWARD-MOTIVATED MEMORY.” In Journal of Cognitive Neuroscience, 227–28. MIT PRESS, 2013.
       Link to Item
    • Johnson, Elizabeth B., Jessica Wilson, Joann Poh, Siti Yaakub, Kavitha Dorairaj, Attillio Rapisarda, Michael Chee, et al. “Midbrain Modulation of Hippocampus Dependent Learning in Singaporeans at Ultra High Risk for the Development of Schizophrenia.” In Biological Psychiatry, 71:254S-254S. ELSEVIER SCIENCE INC, 2012.
       Link to Item
    • Murty, Vishnu P., Siow A. Chong, Mythily Subramaniam, Richard Keefe, Michael Kraus, Joann Poh, Kavitha Dorairaj, Jamie Thong, Yioe L. Bong, and R Alison Adcock. “Amygdala Reactivity in Singaporeans at Ultra High Risk for the Development of Schizophrenia.” In Biological Psychiatry, 69:235S-235S. ELSEVIER SCIENCE INC, 2011.
       Link to Item
    • Johnson, Elizabeth B., and R Alison Adcock. “Generalized Enhancement of Episodic Memory by Prior Reward Experience.” In Biological Psychiatry, 67:85S-85S. ELSEVIER SCIENCE INC, 2010.
       Link to Item
• Teaching & Mentoring
• 

  Recent Courses

  • NEUROBIO 393: Research Independent Study 2019
  • NEUROBIO 793: Research in Neurobiology 2019
  • NEUROSCI 755: Interdisciplinary Program in Cognitive Neuroscience (IPCN) Independent Research Rotation 2019
  • PSY 394: Research Independent Study 2019
  • NEUROSCI 493: Research Independent Study 1 2018
  • NEUROSCI 494: Research Independent Study 2 2018
  • NEUROSCI 150: Research Practicum 2017
  • NEUROSCI 495: Research Independent Study 3 2017
• Scholarly, Clinical, & Service Activities
• 

  Outreach & Engaged Scholarship

  • Bass Connections Faculty Team Member . The Construction of Memory at Duke and in Durham: Using Memory Studies. August 2016 - May 2017  2016 - 2017
  • Bass Connections Faculty Team Member. The Construction of Memory at Duke and in Durham: Using Memory Studies. August 2016 - May 2017  2016 - 2017

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.