https://orcid.org/0000-0001-5409-9155
Overview
My work focuses on the dissection of human traits using multi-omic technologies (genetics, epigenetics, metabolomics and proteomics). I am investigating the basis of several neurological and psychiatric conditions such as neural tube defects and post-traumatic stress disorder. I also study modifiers of sickle cell disease.
Current Duke Appointments & Affiliations
Professor in Medicine
·
2021 - Present
Medicine, Nephrology,
Medicine
Research Professor in Molecular Genetics and Microbiology
·
2014 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Professor in Biostatistics and Bioinformatics
·
2022 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Faculty Network Member of the Duke Institute for Brain Sciences
·
2009 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Member of Duke Molecular Physiology Institute
·
2016 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Scholarly Works
Toxic exposure and rates of suicidal thoughts and behaviors among U.S. military veterans.
Journal article Psychiatry Res · August 2026 Exposure to toxic substances has been linked to poorer mental health among U.S. military veterans broadly, but less is known about specific psychiatric outcomes, such as suicidal thoughts and behaviors (STBs). In the current observational cohort study, we ... Full text Link to item CiteDissecting the pleiotropic genetic architecture of suicide attempt, suicidal ideation, and thirteen correlated traits.
Journal article Eur Neuropsychopharmacol · July 2026 Suicide attempts (SA) and suicidal ideation (SI) are major public health concerns with incompletely understood underlying genetic and molecular mechanisms. We investigated the shared genetic architecture of SA and SI with 13 genetically correlated psychiat ... Full text Link to item CiteDNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.
Journal article EBioMedicine · June 2026 BACKGROUND: Bipolar disorder (BD) is a major mood disorder influenced by both genetic and environmental factors. While DNA methylation from peripheral tissues can reflect both genetic and environmental influences and reveal insights into disease biology, i ... Full text Link to item CiteRecent Grants
Genetics and Genomics Training Grant
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2031Computational Biology and Bioinformatics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031Hematology & Transfusion Medicine
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2031View All Grants
Education
Emory University ·
1997
Ph.D.