Allison Elizabeth Ashley-Koch

Allison Elizabeth Ashley-Koch
Professor in Medicine

One of my major research foci is in the genetic basis of psychiatric and neurological disorders. I am currently involved in studies to dissect the genetic etiology of attention deficit hyperactivity disorder (ADHD), autism, chiari type I malformations, essential tremor, and neural tube defects. Additional research foci include genetic modifiers of sickle cell disease, and genetic contributions to birth outcomes, particularly among African American women.

Current Appointments & Affiliations

Professor in Medicine, Medicine, Nephrology, Medicine 2014
Professor in Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2013
Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2014
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2009
Affiliate of the Center for Child and Family Policy, Center for Child and Family Policy, Sanford School of Public Policy 2015
Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2016

Contact Information

300 N Duke St., Durham, NC 27701
Duke Box 104775, Durham, NC 27701
allison.ashleykoch@duke.edu (919) 684-1805

Background
Education, Training, & Certifications
- Ph.D., Emory University 1997
Duke Appointment History
- Faculty Fellow in the Center for Child and Family Policy, Center for Child and Family Policy, Sanford School of Public Policy 2015
- Professor in Medicine, Medicine, Medical Genetics, Medicine 2013 - 2014
- Assistant Professor in Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2007 - 2013
- Associate Professor in Medicine, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2007 - 2013
- Assistant Professor in Medicine, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2006 - 2007
- Assistant Research Professor in Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2001 - 2007
- Assistant Research Professor in Medicine, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2001 - 2006
- Instructor, Temporary of Medicine, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2001
Recognition
In the News
- DEC 14, 2015 Seattle Times
  
  How the state is missing chances to find deadly birth defect’s cause
Expertise
Global Scholarship
- Expertise
  - United States of America (Country)
- Research
  - Guatemala (Country)
  - United States of America (Country)
Research
Selected Grants
- Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders awarded by National Institutes of Health 2017 - 2021
- Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2021
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Transcriptomic, therapeutic and genetic investigations of sickle cell nephropathy awarded by National Institutes of Health 2016 - 2019
- Decoding schizophrenia-From GWAS to functional regulatory variants awarded by National Institutes of Health 2014 - 2019
- Duke-UNC Clinical Hematology and Transfusion Research Career Development Program awarded by National Institutes of Health 2006 - 2019
- Genetic and Functional Studies of Human Ciliary Syndromes awarded by National Institutes of Health 2005 - 2019
- High-throughput Metabolite Profiling and Genetic Analyses awarded by Doris Duke Charitable Foundation 2015 - 2018
- Behavioral and genetic mechanisms of smoking risk in individuals with ADHD awarded by National Institutes of Health 2012 - 2018
- IPA - Allison Ashley-Koch awarded by Durham Veterans Affairs Medical Center 2016 - 2018
- Identification of Susceptibility Genes for Essential Tremor awarded by Columbia University 2015 - 2018
- Linking ciliary biology to the functional annotation of psychiatric disorders awarded by National Institutes of Health 2016 - 2017
- Genome-wide Association Analysis in the Neurocognitive Outcomes of Depression in the Elderly (NCODE) data set. awarded by University of Connecticut 2017
- Genetic and Environmental Predictors of Combat-Related PTSD awarded by University of Texas Health Science Center at San Antonio 2015 - 2016
- Extension of Hematologic & Clinical Genotype-Phenotype Associations in SCD Using Exome Chip & Metabolomic Analysis awarded by Doris Duke Charitable Foundation 2013 - 2015
- Biorepository Core Lab for the PTSD-TBI Clinical Consortium awarded by University of California - San Diego 2009 - 2015
- Imaging Genetic Predictors of Psychotherapy Outcomes in Unipolar Depression awarded by National Institutes of Health 2012 - 2015
- Linkage and candidate gene analysis in non-syndromic Chiari type I awarded by National Institutes of Health 2009 - 2015
- IPA - Allison Ashley-Koch awarded by Durham Veterans Affairs Medical Center 2012 - 2014
- Neuropharmacology of Response Inhibition in Comorbid ADHD and Nicotine Dependence awarded by National Institutes of Health 2009 - 2014
- Elucidating Outcome and Risk from Improved Exposure Assessment and Mechanistic Studies awarded by University of North Carolina - Chapel Hill 2011 - 2014
- Admixture Mapping of Glaucoma Genes in African Americans awarded by National Institutes of Health 2008 - 2013
- Genes and Alterations in Brain Structure and Function in Depression awarded by National Institutes of Health 2008 - 2012
- Genetic basis of smoking abstinence, smoking reinforcement, and inhibitory control awarded by National Institutes of Health 2009 - 2012
- Recovery Act Funds for Administrative Supplements for Conte Center grant programs awarded by National Institutes of Health 2010 - 2011
- Pulmonary Hypertension in SCD awarded by National Institutes of Health 2005 - 2011
- Candidate Gene Analysis of Persistent AD/HD awarded by National Institutes of Health 2004 - 2010
- Hereditary basis of neural tube defects awarded by National Institutes of Health 1999 - 2010
- Outcome Modifying Genes in Sickle Cell Diseases awarded by National Institutes of Health 2001 - 2008
- Molecular and Genetic Epidemiology of Autism awarded by National Institutes of Health 1997 - 2007
- Molecular and genetic epidemiology of autism awarded by National Institutes of Health 1997 - 2007
- Genetics and epidemiology of essential tremor awarded by National Institutes of Health 2002 - 2007
- Stress, Serotonin Genes, & Health Disparities awarded by National Institute of Environmental Health Science 2000 - 2006
Publications & Artistic Works
Selected Publications
- Book Sections
  - Markunas, CA, Ashley-Koch, AE, Gregory, SG, Markunas, CA, Ashley-Koch, AE, and Gregory, SG. "Genetics of the Chiari i and II malformationsGenetics of the Chiari i and II malformations (PublishedPublished)." In The Chiari Malformations, 93-101. March 1, 2013. Full Text
- Conference Papers
  - Smith, A, Ratanatharathorn, A, Boks, M, Logue, M, Maihofer, A, Kilaru, V, Stein, M, Vermetten, E, Koenen, K, Aiello, A, Baker, D, Hauser, M, Kimbrel, N, Ashley-Koch, A, Luft, B, Bromet, E, Miller, M, Ressler, K, Uddin, M, and Nievergelt, C. "Meta-Analysis of DNA Methylation and PTSD in the Psychiatric Genomics Consortium PTSD Epigenetics Workgroup." November 2017. Link to Item
  - Grotegut, CA, Ngan, E, Garrett, ME, Ashley-Koch, AE, and Swamy, GK. "Single nucleotide polymorphisms in the oxytocin receptor and GRK6 are associated with oxytocin dosing requirements and labor outcomes." January 2017. Link to Item
  - Anderson, BR, Garrett, ME, Soldano, KL, Orringer, EP, Eckman, JR, Francescatto, L, Davis, EE, Gladwin, MT, Gordeuk, VR, Telen, MJ, and Ashley-Koch, AE. "GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes." December 2, 2016. Link to Item
  - Jacob, SA, Novelli, EM, Isenberg, JS, Garrett, ME, Chu, Y, Soldano, KL, Ataga, KI, Telen, MJ, Ashley-Koch, AE, Zhang, Y, and Kato, GJ. "Thrombospondin-1 Polymorphisms Are Associated with Chronic Kidney Disease in Sickle Cell Anemia." December 2, 2016. Link to Item
  - Xu, JZ, Garrett, ME, Soldano, KL, Chen, ST, Ashley-Koch, AE, and Telen, MJ. "Factors Related to the Progression of Sickle Cell Disease Nephropathy." December 2, 2016. Link to Item
  - Garrett, ME, Soldano, KL, Anderson, BR, Telen, MJ, and Ashley-Koch, AE. "Genome-Wide Evaluation of Epistasis with APOL1 Risk Variants in Sickle Cell Disease Nephropathy." December 3, 2015. Link to Item
  - Lancaster, S, Garrett, M, Haswell, C, Marx, C, Hauser, M, Ashley-Koch, A, Morey, R, and Workgrp, M-AMIRECC. "Posttraumatic Stress Disorder and Common Genetic Variants Affect Subcortical Brain Volumes in Recent Military Veterans." December 2015. Link to Item
  - Geisert, EE, Struebing, FL, King, R, Pasquale, LR, Ashley-Koch, AE, Hauser, MA, Allingham, RR, and Wiggs, JL. "GENOMIC LOCI MODULATING GANGLION CELL DEATH FOLLOWING ELEVATED IOP IN THE MOUSE." June 2015. Link to Item
  - King, R, Hauser, MA, Pasquale, LR, Wiggs, JL, Ashley-Koch, AE, Allingham, RR, and Geisert, EE. "Mouse Genomic Loci Modulating Corneal Thickness." June 2015. Link to Item
  - Struebing, FL, King, R, Ashley-Koch, A, Hauser, MA, Allingham, RR, and Geisert, EE. "Interval mapping reveals a quantitative trait locus controlling retinal ganglion cell number in mice." June 2015. Link to Item
  - Kousa, YA, Roushangar, RR, Zhu, H, Lei, Y, Finnell, RH, Fakhouri, WD, Busch, TD, Murray, JC, Bassuk, A, Shaw, GM, Ashley-Koch, A, Gregory, S, Patel, N, Schutte, BC, Leslie, EJ, Williams, TJ, and Chai, Y. "A GENE REGULATORY NETWORK SHARED BETWEEN NEURULATION AND OROFACIAL DEVELOPMENT." April 2015. Link to Item
  - Anderson, BR, Davis, EE, Telen, MJ, and Ashley-Koch, AE. "Evidence for a Dominant Negative Effect Conferred By the APOL1 G2 Sickle Cell Nephropathy Risk Allele in an in Vivo Model." December 6, 2014. Link to Item
  - Elmariah, H, Garrett, ME, Soldano, KL, Ataga, KI, Eckman, JR, Telen, MJ, and Ashley-Koch, AE. "Genes Associated with Survival in Adult Sickle Cell Disease." December 6, 2014. Link to Item
  - Garrett, ME, Soldano, KL, Anderson, BR, Orringer, EP, Eckman, JR, Telen, MJ, and Ashley-Koch, AE. "Genome-Wide Association Study of Glomerular Filtration Rate in a Cohort of Sickle Cell Disease Patients." December 6, 2014. Link to Item
  - Milton, JN, Ashley-Koch, AE, Garrett, ME, Soldano, KL, Orringer, EP, Sebastiani, P, Dworkis, DA, Quillen, K, Steinberg, MH, and Telen, MJ. "Genes Associated with Alloimmunization to Blood Group Antigens in Sickle Cell Disease." December 6, 2014. Link to Item
  - Taylor, W, Saleh, A, Potter, G, Boyd, B, McQuoid, D, Kudra, K, Ashley-Koch, A, and MacFall, J. "The Influence of APOE Genotype on Aging's Effect on Brain Structure and Cognition in Younger Adults with and without Depression." December 2014. Link to Item
  - Kimbrel, N, Hauser, M, Garrett, M, Ashley-Koch, A, Liu, Y, Dennis, M, Klein, R, Knopik, V, and Beckham, J. "Effect of the APOE epsilon 4 allele and combat exposure on PTSD and psychiatric comorbidity." November 2014. Link to Item
  - Anderson, BR, Davis, EE, Telen, MJ, and Ashley-Koch, AE. "In Vivo Modeling Of Genetic Mechanisms Associated With Sickle Cell Disease Nephropathy." November 15, 2013. Link to Item
  - Babyak, MA, Becker, RC, Helms, MJ, Jiang, R, Singh, A, Brummett, BH, Siegler, IC, Ashley-Koch, A, Ortel, T, and Williams, RB. "ADRENERGIC GENE VARIANTS ARE ASSOCIATED WITH PLATELET AGGREGATION TO EPINEPHRINE." April 2013. Link to Item
  - Napier, MD, Poole, C, Satten, GA, Ashley-Koch, A, Marrie, RA, and Williamson, DM. "Heavy Metals, Organic Solvents and Multiple Sclerosis: An Exploratory Analysis of Gene-environment Interactions." November 2012. Link to Item
  - Garrett, ME, Moylan, CA, Gibson, J, Yang, H, Pang, H, Dellinger, A, Suzuki, A, Tillmann, HL, Guy, CD, Abdelmalek, MF, Murphy, SK, Diehl, AM, Hauser, M, and Ashley-Koch, AE. "Expression QTL analysis of a gene expression signature which predicts advanced non-alcoholic fatty liver disease." October 2012. Link to Item
  - Moylan, CA, Yang, H, Pang, H, Dellinger, A, Suzuki, A, Tillmann, HL, Guy, CD, Ashley-Koch, AE, Garrett, ME, Abdelmalek, MF, Hauser, MA, Murphy, SK, and Diehl, AM. "Epigenetic Regulation of Gene Expression in NAFLD." May 2012. Link to Item
  - Bae, HT, Baldwin, CT, Gladwin, MT, Ashley-Koch, AE, Garrett, M, Soldano, K, Taylor, JG, Kato, GJ, Telen, MJ, Sebastiani, P, Steinberg, MH, and Klings, ES. "An Elevated Tricuspid Regurgitant Jet Velocity in Sickle Cell Disease Is Associated with Polymorphisms in Genes Impacting Innate Immunity." November 18, 2011. Link to Item
  - Barber, LA, Soldano, K, Garrett, M, Orringer, EP, Eckman, JR, Telen, MJ, and Ashley-Koch, AE. "Inflammatory Polymorphisms Link the Risk of Acute Chest Syndrome with Asthma in Adults with Sickle Cell Disease." November 18, 2011. Link to Item
  - Bidwell, LC, Garrett, ME, McClernon, FJ, Fuemmeler, BF, Williams, RB, Ashley-Koch, AE, and Kollins, SH. "Genotype and ADHD symptoms interact to predict adolescents' early smoking experiences in an epidemiological sample." November 2011. Link to Item
  - van Waes, JG, Maddox, J, Ashley-Koch, A, Gregory, S, Torres de Matute, O, Voss, KA, and Riley, RT. "Evaluating human exposure to fumonisins in Guatemala and its possible role as a contributing factor to neural tube defects." June 2011. Link to Item
  - Taylor, WD, Ashley-Koch, A, Benjamin, S, McQuoid, D, Steffens, DC, Krishnan, RR, and Hauser, E. "Genotypic Differences in Angiotensin Receptor Genes in Late-Life Depression." May 1, 2011. Link to Item
  - Benjamin, S, Payne, M, Ashley-Koch, A, McQuoid, D, MacFall, J, and Taylor, WD. "Variation in the AGTR1 Gene and Altered Frontotemporal Structural Connectivity in Late-Life Depression." March 2011. Link to Item
  - Ashley-Koch, AE, Garrett, M, Soldano, K, Barber, LA, and Telen, MJ. "Hydroxyurea Induces Genome-Wide Epigenetic Changes In Sickle Cell Disease." November 19, 2010. Link to Item
  - Barber, LA, Garrett, M, Soldano, K, Orringer, EP, Eckman, JR, Telen, MJ, and Ashley-Koch, AE. "Anti-Inflammatory Markers Are Associated with Glomerular Filtration Rate In Adults with Sickle Cell Disease." November 19, 2010. Link to Item
  - Okocha, E, Garrett, M, Soldano, K, De Castro, LM, Jonassaint, J, Orringer, EP, Eckman, JR, telen, MJ, and Ashley-Koch, AE. "Genetic Variation In MYH9 Is Associated with Sickle Cell Disease Nephropathy." November 19, 2010. Link to Item
  - Swamy, GK, Garrett, ME, Ashley-Koch, AE, and Miranda, ML. "Genetic variation in G-protein coupled receptor kinase-5 and preeclampsia." December 2009. Full Text Link to Item
  - Barber, LA, Ashley-Koch, AE, Garrett, ME, Soldano, KL, and Telen, MJ. "Polymorphisms in TNF alpha Are Associated with Cerebrovascular Events in Sickle Cell Disease." November 20, 2009. Link to Item
  - Timofeev, N, Milton, JN, Hartley, SW, Sherva, R, Sebastiani, P, Dworkis, DA, Klings, ES, Farrer, L, Telen, MJ, Ashley-Koch, AE, Garrett, ME, Chui, DHK, Baldwin, CT, and Steinberg, MH. "Genome-Wide Studies in Sickle Cell Anemia Show Associations Between SNPs in the Olfactory Receptor Gene Cluster and Fetal Hemoglobin Concentration." November 20, 2009. Link to Item
  - El Khatib, A, Ashley-Koch, A, Kail, M, Collins, A, Jonassaint, J, Adam, SS, Ataga, KI, Eckman, JR, Orringer, EP, Greenberg, CS, and Telen, MJ. "Further investigation of the role of factor XIII in priapism associated with SCD." November 16, 2007. Link to Item
  - Jonassaint, CR, Jonassaint, JC, Ashley-Koch, A, Adam, SS, Telen, MJ, and De Castro, LM. "The effects of chronic opiates pain therapy in sickle cell anemia." November 16, 2007. Link to Item
  - Ashley-Koch, A, Cuccaro, M, Tran-Viet, KN, Cope, H, Krishnan, R, Pericak-Vance, M, Wright, H, and Zuchner, S. "Trichotillomania is associated with mutations in SLITRK1." October 5, 2006. Link to Item
  - Cuccaro, M, Collins, S, Anastopoulos, A, Lachiewicz, A, Kane, E, FitzGerald, D, Kail, M, Exelbierd, L, Gilbert, J, and Ashley-Koch, A. "Polymorphisms in DRD2 are associated with AD/HD." October 5, 2006. Link to Item
  - Kollins, S, Epstein, J, Tonev, S, Anastopoulos, A, Lachiewicz, A, Fitzgerald, D, Kane, E, Kail, M, Cuccaro, M, Exelbierd, L, Gilbert, J, and Ashley-Koch, A. "Genetic associations with reaction time variability in AD/HD." October 5, 2006. Link to Item
  - Afenyi-Annan, AN, Graham, FL, Galloway, J, Price, J, Combs, MR, Vance, JM, Ashley-Koch, A, and Telen, MJ. "Allolimmunization and clinical disease severity in sickle cell disease." September 2006. Link to Item
  - Afenyi-Annan, AN, Graham, FL, Galloway, J, Price, J, Combs, MR, Vance, JM, Ashley-Koch, A, and Telen, MJ. "Duffy genotype is associated with sickle cell nephropathy." September 2006. Link to Item
  - Zuchner, S, Wang, G, Nance, MA, Ashley-Koch, AE, and Pericak-Vance, MA. "Hereditary spastic paraplegia is caused by mutations in the novel mitochondrial protein REEP1." 2006. Link to Item
  - Brummett, B, Ashley-Koch, A, Kuhn, C, Kail, M, Vance, J, Zuchner, S, Siegler, I, Barefoot, J, and Williams, R. "5HTTLPR genotypes and environmental stress interact to affect sleep quality." December 2005. Link to Item
  - Williams, R, Kail, M, Speer, M, Brummett, B, Zuchner, S, Siegler, I, Barefoot, J, Swamy, G, Brown, H, Miranda, ML, and Ashley-Koch, A. "Candidate gene polymorphisms and birth weight (BW) in the national longitudinal study of adolescent health (add health)." December 2005. Link to Item
  - Ashley-Koch, AE, De Castro, LM, Lennon-Graham, F, Jonassaint, J, Jackson, TL, Price, J, Galloway, J, Jones, S, Randall, E, Packman, C, Knupp, C, Eckman, JR, Orringer, EP, Vance, JM, and Telen, MJ. "Clinical and genetic profiles of the aging sickle cell patient." November 16, 2005. Link to Item
  - Ashley-Koch, AE, De Castro, LM, Lennon-Graham, F, Jonassaint, J, Jackson, TL, Price, J, Galloway, J, Jones, S, Randall, E, Packman, C, Knupp, C, Eckman, JR, Redding-Lallinger, R, Orringer, EP, Vance, JM, and Telen, MJ. "Priapism in SCD: Clinical and genetic correlations." November 16, 2005. Link to Item
  - Ashley-Koch, AE, Zhang, L, Knauer, S, Haynes, C, Salzman, C, and Menold, MM. "Results from 10k SNP genomic screen provide further evidence for genetic heterogeneity in essential tremor." 2005. Link to Item
  - Ashley-Koch, AE, De Castro, L, Lennon-Graham, F, Jonassaint, J, Jackson, TL, Price, J, Galloway, J, Ataga, KI, Orringer, EP, Vance, JM, and Telen, MJ. "Genetic polymorphisms associated with risk for pulmonary hypertension and proteinuria in sickle cell disease." November 16, 2004. Link to Item
  - De Castro, LM, Jonassaint, JC, Graham, FL, Ashley-Koch, A, and Telen, MJ. "Pulmonary hypertension in SS, SC and so thalassemia: Prevalence, associated clinical syndromes, and mortality." November 16, 2004. Link to Item
  - Eyler, CE, Jackson, TL, De Castro, LM, Zennadi, R, Vance, JM, Ashley-Koch, A, and Telen, MJ. "Effects of single nucleotide polymorphisms of the beta(2) adrenergic receptor and of adenylate cyclase on sickle red cell adhesion to laminin." November 16, 2004. Link to Item
  - Ashley-Koch, AE, Jaworski, J, Mei, H, Menold, M, Rabionet, R, Skaar, D, Ritchie, M, Abramson, RK, Wright, HH, Delong, GR, Cuccaro, ML, Gilbert, JR, Martin, ER, and Pericak-Vance, MA. "Evidence for gene-gene interactions influencing susceptibility to autistic disorder." September 15, 2004. Link to Item
  - Menold, MM, Jaworski, JM, Dementieva, Y, Wolpert, CM, Donnelly, S, Abramson, RK, Wright, HH, Ashley-Koch, A, Cuccaro, ML, Pericak-Vance, MA, and Gilbert, JR. "Mutation screening and SNP analysis of GABRB3 in a subset of autistic individuals." September 15, 2004. Link to Item
  - Schug, MD, Anastopoulos, A, Kollins, S, Hennis, L, Nelson, S, Mehltretter, L, Gilbert, J, Cuccaro, M, and Ashley-Koch, A. "The genetics of AD/HD: Subtyping, comorbidity and developmental considerations." September 15, 2004. Link to Item
  - Ashley-Koch, AE, Zhang, L, Stajich, JM, West, S, Pericak-Vance, MA, and Gilbert, JR. "A genomic screen for a novel essential tremor locus." 2004. Link to Item
  - Gilbert, JR, Stajich, JM, Knauer, S, Scott, B, Vance, JM, and Ashley-Koch, AE. "Prevalence and severity of tremor in familial essential tremor." 2004. Link to Item
  - Stajich, JM, Knauer, S, Scott, B, Vance, JM, Ashley-Koch, AE, and Gilbert, JR. "Prevalence of tandem gait and intention tremor in familial essential tremor." 2004. Link to Item
  - De Castro, LM, Jonassaint, JC, Rainey, S, Motley, R, Jones, S, Galloway, J, Zhang, L, Uchiyama, T, Eckman, JR, Orringer, EP, Ashley-Koch, AE, Vance, JM, and Telen, MJ. "B-CAM/LU polymorphisms: Effect on sickle cell disease outcomes and cell adhesion." November 16, 2003. Link to Item
  - Telen, MJ, Ashley-Koch, AE, Zhang, L, Jonassaint, J, Rainey, S, Motley, R, Jones, S, Galloway, J, Uchiyama, T, Eckman, JR, Orringer, EP, and Vance, JM. "Examination of a VCAM1 polymorphism as a risk modifier for clinical outcomes in sickle cell disease." November 16, 2003. Link to Item
  - Ashley-Koch, AE, Martin, ER, Jaworski, J, Menold, MM, Haynes, CA, Cuccaro, ML, Gilbert, JR, and Pericak-Vance, MA. "Examination of multilocus association of the GABAA receptor subunit genes in multiplex autism families." November 2003. Link to Item
  - De Castro, LM, Jonassaint, J, Rainey, S, Motley, R, Jones, S, Galloway, J, Zhang, L, Uchiyama, T, Eckman, JR, Orringer, EP, Ashley-Koch, AE, Vance, JM, and Telen, MJ. "B-CAM/LU modifies sickle cell disease severity." November 2003. Link to Item
  - Jaworski, J, Ashley-Koch, AE, Menold, M, Abramson, RK, DeLong, GR, Wright, HH, Cuccaro, ML, Gilbert, JR, and Pericak-Vancl, MA. "Investigation of parent of origin effects for Autism susceptibility loci on chromosomes 2, 7 and 15." November 2003. Link to Item
  - Svenson, IK, Kloos, MT, Gaskell, PC, Nance, MA, Garbern, JY, Pericak-Vance, MA, Ashley-Koch, AE, and Marchuk, DA. "An intragenic modifier of hereditary spastic paraplegia due to spastin gene mutation suggests a role for cyclin-dependent kinase 5 in HSP pathogenesis." November 2003. Link to Item
  - Telen, MJ, Ashley-Koch, AE, Zhang, L, Jonassaint, J, Rainey, S, Motley, R, Jones, S, Galloway, J, Uchiyama, T, Eckman, JR, Orringer, EP, and Vance, JM. "Examination of VCAM1 as a modulator of stroke risk in sickle cell disease." November 2003. Link to Item
  - Zhang, F, Stajich, J, West, S, Smith, R, Vance, J, Pericak-Vance, M, Ashley-Koch, A, and John, J. "A genomic screen of essential tremor." November 2003. Link to Item
  - Zhang, L, Kloos, MT, West, S, Gaskell, PC, Svenson, IK, Pericak-Vance, MA, Marchuk, DA, and Ashley-Koch, AE. "A Genomic screen reveals evidence for novel SPG loci." November 2003. Link to Item
  - Kloos, MT, Reid, E, Ashley-Koch, A, Hughes, L, Bevan, S, Svenson, I, Gaskell, PC, Dearlove, A, Pericak-Vance, MA, Rubinsztein, DC, and Marchuk, DA. "A kinesin heavy chain (KIF5A) mutation in Hereditary Spastic Paraplegia (SPG10)." October 2002. Link to Item
  - Haines, J, Crunk, A, McFarland, L, Scott, W, Gaskell, PC, Shao, YJ, Ashley-Koch, A, and Pericak-Vance, M. "Examination of dementia of the Alzheimer type in the Amish." 2002. Link to Item
  - Ashley-Koch, A, Agusti, A, Calverley, P, Coxon, H, Donner, C, Make, B, Muller, N, Pare, P, Rennard, S, Vestbo, J, Wouters, E, Franklin, A, Hall, M, Haynes, C, Butrim, J, Pericak-Vance, MA, Middleton, LT, Foster, C, Silverman, EK, Lomas, DA, and Pulmon, GCO. "International network to investigate the genetics of Chronic Obstructive Pulmonary Disease." October 2001. Link to Item
  - Abuya, P, Ashley-Koch, A, Wolpert, CM, Menold, MM, Matsumoto, N, Basu, S, Greenblatt, DM, Powell, CM, Cuccaro, ML, Ledbetter, DH, Green, ED, Vance, JM, Pericak-Vance, MA, and Gilbert, JR. "Isolation and analysis of Autism candidate genes on 7q." October 2000. Link to Item
  - Ashley-Koch, A, Menold, M, Joyner, K, Mason, S, Poole, C, Donnelly, S, Wolpert, C, Ravan, S, Abramson, RK, DeLong, GR, Cuccaro, ML, Von Wendt, L, McClain, C, Wright, HH, Vance, JM, Gilbert, JG, and Pericak-Vance, MA. "Examination of epigenetic factors and gene-gene interactions influencing genetic susceptibility at chromosomes 7 and 15 for autistic disorder." October 2000. Link to Item
  - Gaskell, PC, Ashley-Koch, A, Bonner, ER, West, SG, Wolpert, CM, Warner, C, Farrell, CD, Svenson, IK, Marchuk, DA, Tim, RW, Boustany, RM, Vance, JM, Scott, WK, and Pericak-Vance, MA. "Fine mapping and genetic heterogeneity in autosomal dominant familial spastic paraplegia." October 2000. Link to Item
  - Haines, JL, Ashley-Koch, A, Jackson, CE, Booze, M, Ribble, RC, Rimmler, JB, Garcia, ME, Vance, JM, Barcellos, L, Lincoln, R, Hauser, SL, Oksenberg, JR, and Pericak-Vance, MA. "A genomic screen for multiple sclerosis loci in a San Marino population supports the presence of a locus on 19q." October 2000. Link to Item
  - Hall, JL, Ashley-Koch, A, Gaskell, PC, Jackson, CE, Bailey, LR, Scott, WK, Haines, JL, and Pericak-Vance, MA. "A genomic screen for dementia in an extended Amish family." October 2000. Link to Item
  - Kim, SJ, Menold, MM, Zaeem, L, Ashley-Koch, A, Bass, MP, Vance, JM, Pericak-Vance, MA, and Gilbert, JR. "CpG island and gene mapping in the Austistic Disorder region on chromosome 15q11-13." October 2000. Link to Item
  - Santangelo, SL, Buxbaum, J, Silverman, J, Pericak-Vance, M, Ashley-Koch, A, and Autism, CLS. "Confirmatory evidence of linkage for autism to 7q based on combined analysis of three independent data sets." October 2000. Link to Item
  - Ashley-Koch, A, Wolpert, CM, Menold, MM, Zaeem, L, Basu, S, Donnelly, SL, Ravan, SA, Powell, CM, Qumsiyeh, MB, Alysworth, AS, Vance, JM, Gilbert, JG, Wright, HH, Abramson, RK, DeLong, GR, Cuccaro, ML, and Pericak-Vance, MA. "Evidence for a paternal effect on chromosome 7 in Autistic Disorder." October 1999. Link to Item
  - Basu, S, Ashley-Koch, A, Wolpert, CM, Menold, MM, Matsumoto, N, Powell, CM, Qumsiyeh, MB, Cuccaro, ML, Ledbetter, DH, Green, ED, Vance, JM, Pericak-Vance, MA, and Gilbert, JR. "Autistic Disorder and chromosome 7: Analysis of an inversion breakpoint in a multiplex family." October 1999. Link to Item
  - Ashley-Koch, A, Wolpert, CM, Zaeem, L, Menold, MM, Basu, S, Donnelly, SL, Ravan, SA, Powell, CM, Qumsiyeh, MB, Aylsworth, AS, Vance, JM, Gilbert, JG, Wright, HH, Abramson, RK, DeLong, GR, Cuccaro, ML, and Pericak-Vance, MA. "Autistic disorder and chromosome 7: Evidence for a paternal effect." September 1999. Link to Item
  - Basu, S, Ashley-Koch, A, Wolpert, C, Menold, M, Matsumoto, N, Powell, C, Qumsiyeh, MB, Cuccaro, M, Scherer, S, Ledbetter, DH, Green, E, Vance, JM, Pericak-Vance, MA, and Gilbert, R. "Characterization of an inversion breakpoint in a multiplex autistic disorder family: Defining the candidate region on chromosome 7q." September 1999. Link to Item
  - Savage, A, Sun, F, Crawford, DC, Ashley, AE, Yang, Q, and Sherman, SL. "Sequential sib-pair and association studies to detect genes in quantitative traits." December 1, 1997. Full Text
- Journal Articles
  - Nievergelt, CM, Ashley-Koch, AE, Dalvie, S, Hauser, MA, Morey, RA, Smith, AK, and Uddin, M. "Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative. (Accepted)" Biological psychiatry 83, no. 10 (May 2018): 831-839. (Review) Full Text
  - Duncan, LE, Ratanatharathorn, A, Aiello, AE, Almli, LM, Amstadter, AB, Ashley-Koch, AE, Baker, DG, Beckham, JC, Bierut, LJ, Bisson, J, Bradley, B, Chen, C-Y, Dalvie, S, Farrer, LA, Galea, S, Garrett, ME, Gelernter, JE, Guffanti, G, Hauser, MA, Johnson, EO, Kessler, RC, Kimbrel, NA, King, A, Koen, N, Kranzler, HR, Logue, MW, Maihofer, AX, Martin, AR, Miller, MW, Morey, RA, Nugent, NR, Rice, JP, Ripke, S, Roberts, AL, Saccone, NL, Smoller, JW, Stein, DJ, Stein, MB, Sumner, JA, and Uddin, M et al. "Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability." Molecular psychiatry 23, no. 3 (March 2018): 666-673. Full Text Open Access Copy
  - Bailey, JNC, Gharahkhani, P, Kang, JH, Butkiewicz, M, Sullivan, DA, Weinreb, RN, Aschard, H, Allingham, RR, Ashley-Koch, A, Lee, RK, Moroi, SE, Brilliant, MH, Wollstein, G, Schuman, JS, Fingert, JH, Budenz, DL, Realini, T, Gaasterland, T, Scott, WK, Singh, K, Sit, AJ, Igo, RP, Song, YE, Hark, L, Ritch, R, Rhee, DJ, Vollrath, D, Zack, DJ, Medeiros, F, Vajaranant, TS, Chasman, DI, Christen, WG, Pericak-Vance, MA, Liu, Y, Kraft, P, Richards, JE, Rosner, BA, Hauser, MA, Craig, JE, and Burdon, KP et al. "Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets." Investigative ophthalmology & visual science 59, no. 2 (February 2018): 629-636. Full Text
  - Wolf, EJ, Maniates, H, Nugent, N, Maihofer, AX, Armstrong, D, Ratanatharathorn, A, Ashley-Koch, AE, Garrett, M, Kimbrel, NA, Lori, A, Va Mid-Atlantic Mirecc Workgroup, , Aiello, AE, Baker, DG, Beckham, JC, Boks, MP, Galea, S, Geuze, E, Hauser, MA, Kessler, RC, Koenen, KC, Miller, MW, Ressler, KJ, Risbrough, V, Rutten, BPF, Stein, MB, Ursano, RJ, Vermetten, E, Vinkers, CH, Uddin, M, Smith, AK, Nievergelt, CM, and Logue, MW. "Traumatic stress and accelerated DNA methylation age: A meta-analysis." Psychoneuroendocrinology (December 27, 2017). Full Text
  - Morey, RA, Davis, SL, Garrett, ME, Haswell, CC, Mid-Atlantic MIRECC Workgroup, , Marx, CE, Beckham, JC, McCarthy, G, Hauser, MA, and Ashley-Koch, AE. "Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls." Translational psychiatry 7, no. 11 (November 30, 2017): 1265-. Full Text
  - Polimanti, R, Amstadter, AB, Stein, MB, Almli, LM, Baker, DG, Bierut, LJ, Bradley, B, Farrer, LA, Johnson, EO, King, A, Kranzler, HR, Maihofer, AX, Rice, JP, Roberts, AL, Saccone, NL, Zhao, H, Liberzon, I, Nievergelt, CM, Koenen, KC, Gelernter, J, Duncan, LE, Chen, CY, Ratanatharathorn, A, Aiello, AE, Ashley-Koch, AE, Garrett, ME, Hauser, MA, Beckham, JC, Kimbrel, NA, Bisson, J, Dalvie, S, Galea, S, Gelernter, JE, Guffanti, G, Ressler, KJ, Kessler, RC, Koen, N, Stein, DJ, Logue, MW, and Miller, MW et al. "A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder." Genome Medicine 9, no. 1 (November 27, 2017). Full Text
  - Aschard, H, Kang, JH, Iglesias, AI, Hysi, P, Cooke Bailey, JN, Khawaja, AP, Allingham, RR, Ashley-Koch, A, Lee, RK, Moroi, SE, Brilliant, MH, Wollstein, G, Schuman, JS, Fingert, JH, Budenz, DL, Realini, T, Gaasterland, T, Scott, WK, Singh, K, Sit, AJ, Igo, RP, Song, YE, Hark, L, Ritch, R, Rhee, DJ, Gulati, V, Haven, S, Vollrath, D, Zack, DJ, Medeiros, F, Weinreb, RN, Cheng, C-Y, Chasman, DI, Christen, WG, Pericak-Vance, MA, Liu, Y, Kraft, P, Richards, JE, Rosner, BA, and Hauser, MA et al. "Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis." European journal of human genetics : EJHG 25, no. 11 (November 2017): 1261-1267. Full Text
  - Grotegut, CA, Ngan, E, Garrett, ME, Miranda, ML, Ashley-Koch, AE, and Swamy, GK. "The association of single-nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes." American journal of obstetrics and gynecology 217, no. 3 (September 2017): 367.e1-367.e9. Full Text
  - Ratanatharathorn, A, Boks, MP, Maihofer, AX, Aiello, AE, Amstadter, AB, Ashley-Koch, AE, Baker, DG, Beckham, JC, Bromet, E, Dennis, M, Garrett, ME, Geuze, E, Guffanti, G, Hauser, MA, Kilaru, V, Kimbrel, NA, Koenen, KC, Kuan, P-F, Logue, MW, Luft, BJ, Miller, MW, Mitchell, C, Nugent, NR, Ressler, KJ, Rutten, BPF, Stein, MB, Vermetten, E, Vinkers, CH, Youssef, NA, VA Mid-Atlantic MIRECC Workgroup, , PGC PTSD Epigenetics Workgroup, , Uddin, M, Nievergelt, CM, and Smith, AK. "Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline." American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 174, no. 6 (September 2017): 619-630. Full Text
  - Jacob, SA, Novelli, EM, Isenberg, JS, Garrett, ME, Chu, Y, Soldano, K, Ataga, KI, Telen, MJ, Ashley-Koch, A, Gladwin, MT, Zhang, Y, and Kato, GJ. "Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia." American journal of hematology 92, no. 3 (March 2017): E31-E34. (Letter) Full Text
  - Tan, PL, Garrett, ME, Willer, JR, Campochiaro, PA, Campochiaro, B, Zack, DJ, Ashley-Koch, AE, and Katsanis, N. "Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration." Investigative ophthalmology & visual science 58, no. 3 (March 2017): 1570-1576. Full Text
  - Pasquale, LR, Aschard, H, Kang, JH, Bailey, JNC, Lindström, S, Chasman, DI, Christen, WG, Allingham, RR, Ashley-Koch, A, Lee, RK, Moroi, SE, Brilliant, MH, Wollstein, G, Schuman, JS, Fingert, J, Budenz, DL, Realini, T, Gaasterland, T, Gaasterland, D, Scott, WK, Singh, K, Sit, AJ, Igo, RP, Song, YE, Hark, L, Ritch, R, Rhee, DJ, Gulati, V, Havens, S, Vollrath, D, Zack, DJ, Medeiros, F, Weinreb, RN, Pericak-Vance, MA, Liu, Y, Kraft, P, Richards, JE, Rosner, BA, Hauser, MA, Haines, JL, and Wiggs, JL. "Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample." Menopause (New York, N.Y.) 24, no. 2 (February 2017): 150-156. Full Text
  - Taylor, WD, Boyd, B, Turner, R, McQuoid, DR, Ashley-Koch, A, MacFall, JR, Saleh, A, and Potter, GG. "APOE ε4 associated with preserved executive function performance and maintenance of temporal and cingulate brain volumes in younger adults." Brain imaging and behavior 11, no. 1 (February 2017): 194-204. Full Text
  - Hauser, MA, Garrett, ME, Liu, Y, Dennis, MF, Kimbrel, NA, Veterans Affairs Mid-Atlantic Mental Illness Research Education And Clinical Center Workgroup, , Beckham, JC, and Ashley-Koch, AE. "Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder." Journal of psychiatric research 84 (January 2017): 59-61. Full Text
  - Carnes, MU, Allingham, RR, Ashley-Koch, A, and Hauser, MA. "Transcriptome analysis of adult and fetal trabecular meshwork, cornea, and ciliary body tissues by RNA sequencing." Experimental eye research 167 (November 30, 2016): 91-99. Full Text
  - Hicks, JE, Konidari, I, Scott, BL, Stajich, JM, Ashley-Koch, AE, Gilbert, JR, and Scott, WK. "Linkage of familial essential tremor to chromosome 5q35." Movement disorders : official journal of the Movement Disorder Society 31, no. 7 (July 2016): 1059-1062. Full Text
  - Bailey, JNC, Loomis, SJ, Kang, JH, Allingham, RR, Gharahkhani, P, Khor, CC, Burdon, KP, Aschard, H, Chasman, DI, Igo, RP, Hysi, PG, Glastonbury, CA, Ashley-Koch, A, Brilliant, M, Brown, AA, Budenz, DL, Buil, A, Cheng, C-Y, Choi, H, Christen, WG, Curhan, G, De Vivo, I, Fingert, JH, Foster, PJ, Fuchs, C, Gaasterland, D, Gaasterland, T, Hewitt, AW, Hu, F, Hunter, DJ, Khawaja, AP, Lee, RK, Li, Z, Lichter, PR, Mackey, DA, McGuffin, P, Mitchell, P, Moroi, SE, Perera, SA, Pepper, KW, Qi, Q, and Realini, T et al. "Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma." Nature genetics 48, no. 2 (February 2016): 189-194. Full Text
  - Doss, JF, Jonassaint, JC, Garrett, ME, Ashley-Koch, AE, Telen, MJ, and Chi, J-T. "Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease." PloS one 11, no. 4 (January 2016): e0152895-. Full Text
  - Napier, MD, Poole, C, Satten, GA, Ashley-Koch, A, Marrie, RA, and Williamson, DM. "Heavy metals, organic solvents, and multiple sclerosis: An exploratory look at gene-environment interactions." Archives of environmental & occupational health 71, no. 1 (January 2016): 26-34. Full Text
  - PsychENCODE Consortium, , Akbarian, S, Liu, C, Knowles, JA, Vaccarino, FM, Farnham, PJ, Crawford, GE, Jaffe, AE, Pinto, D, Dracheva, S, Geschwind, DH, Mill, J, Nairn, AC, Abyzov, A, Pochareddy, S, Prabhakar, S, Weissman, S, Sullivan, PF, State, MW, Weng, Z, Peters, MA, White, KP, Gerstein, MB, Amiri, A, Armoskus, C, Ashley-Koch, AE, Bae, T, Beckel-Mitchener, A, Berman, BP, Coetzee, GA, Coppola, G, Francoeur, N, Fromer, M, Gao, R, Grennan, K, Herstein, J, Kavanagh, DH, Ivanov, NA, and Jiang, Y et al. "The PsychENCODE project." Nature neuroscience 18, no. 12 (December 2015): 1707-1712. (Review) Full Text Open Access Copy
  - Hauser, MA, Aboobakar, IF, Liu, Y, Miura, S, Whigham, BT, Challa, P, Wheeler, J, Williams, A, Santiago-Turla, C, Qin, X, Rautenbach, RM, Ziskind, A, Ramsay, M, Uebe, S, Song, L, Safi, A, Vithana, EN, Mizoguchi, T, Nakano, S, Kubota, T, Hayashi, K, Manabe, S-I, Kazama, S, Mori, Y, Miyata, K, Yoshimura, N, Reis, A, Crawford, GE, Pasutto, F, Carmichael, TR, Williams, SEI, Ozaki, M, Aung, T, Khor, C-C, Stamer, WD, Ashley-Koch, AE, and Allingham, RR. "Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus." Human molecular genetics 24, no. 22 (November 2015): 6552-6563. Full Text
  - Riley, RT, Torres, O, Matute, J, Gregory, SG, Ashley-Koch, AE, Showker, JL, Mitchell, T, Voss, KA, Maddox, JR, and Gelineau-van Waes, JB. "Evidence for fumonisin inhibition of ceramide synthase in humans consuming maize-based foods and living in high exposure communities in Guatemala." Molecular nutrition & food research 59, no. 11 (November 2015): 2209-2224. Full Text
  - Anderson, BR, Howell, DN, Soldano, K, Garrett, ME, Katsanis, N, Telen, MJ, Davis, EE, and Ashley-Koch, AE. "Correction: In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress." PLoS genetics 11, no. 9 (September 17, 2015): e1005459-. Full Text
  - Ashley-Koch, AE, Garrett, ME, Gibson, J, Liu, Y, Dennis, MF, Kimbrel, NA, Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, , Beckham, JC, and Hauser, MA. "Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans." Journal of affective disorders 184 (September 2015): 225-234. Full Text
  - Kimbrel, NA, Garrett, ME, Dennis, MF, Liu, Y, Patanam, I, Workgroup, VM-AM, Ashley-Koch, AE, Hauser, MA, and Beckham, JC. "Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder." Psychiatry research 229, no. 1-2 (September 2015): 326-331. Full Text
  - Cope, H, Garrett, ME, Gregory, S, and Ashley-Koch, A. "Pregnancy continuation and organizational religious activity following prenatal diagnosis of a lethal fetal defect are associated with improved psychological outcome." Prenatal diagnosis 35, no. 8 (August 2015): 761-768. Full Text
  - Anderson, BR, Howell, DN, Soldano, K, Garrett, ME, Katsanis, N, Telen, MJ, Davis, EE, and Ashley-Koch, AE. "In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress." PLoS genetics 11, no. 7 (July 6, 2015): e1005349-. Full Text Open Access Copy
  - Li, Z, Allingham, RR, Nakano, M, Jia, L, Chen, Y, Ikeda, Y, Mani, B, Chen, L-J, Kee, C, Garway-Heath, DF, Sripriya, S, Fuse, N, Abu-Amero, KK, Huang, C, Namburi, P, Burdon, K, Perera, SA, Gharahkhani, P, Lin, Y, Ueno, M, Ozaki, M, Mizoguchi, T, Krishnadas, SR, Osman, EA, Lee, MC, Chan, ASY, Tajudin, L-SA, Do, T, Goncalves, A, Reynier, P, Zhang, H, Bourne, R, Goh, D, Broadway, D, Husain, R, Negi, AK, Su, DH, Ho, C-L, Blanco, AA, Leung, CKS, Wong, TT, Yakub, A, Liu, Y, Nongpiur, ME, and Han, JC et al. "A common variant near TGFBR3 is associated with primary open angle glaucoma." Human molecular genetics 24, no. 13 (July 2015): 3880-3892. Full Text
  - Riley, RT, Showker, JL, Lee, CM, Zipperer, CE, Mitchell, TR, Voss, KA, Zitomer, NC, Torres, O, Matute, J, Gregory, SG, Ashley-Koch, AE, Maddox, JR, Gardner, N, and Gelineau-Van Waes, JB. "A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans." Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 32, no. 6 (June 3, 2015): 934-949. Full Text
  - Telen, MJ, Afenyi-Annan, A, Garrett, ME, Combs, MR, Orringer, EP, and Ashley-Koch, AE. "Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival." Transfusion 55, no. 6 Pt 2 (June 2015): 1378-1387. Full Text
  - Telen, MJ, Afenyi-Annan, A, Garrett, ME, Combs, MR, Orringer, EP, and Ashley-Koch, AE. "Alloimmunization in sickle cell disease: Changing antibody specificities and association with chronic pain and decreased survival." Transfusion 55, no. 6 (June 1, 2015): 1378-1387. Full Text
  - Kimbrel, NA, Hauser, MA, Garrett, M, Ashley-Koch, A, Liu, Y, Dennis, MF, Klein, RC, Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, , and Beckham, JC. "EFFECT OF THE APOE ε4 ALLELE AND COMBAT EXPOSURE ON PTSD AMONG IRAQ/AFGHANISTAN-ERA VETERANS." Depression and anxiety 32, no. 5 (May 2015): 307-315. Full Text
  - Roberson, EC, Dowdle, WE, Ozanturk, A, Garcia-Gonzalo, FR, Li, C, Halbritter, J, Elkhartoufi, N, Porath, JD, Cope, H, Ashley-Koch, A, Gregory, S, Thomas, S, Sayer, JA, Saunier, S, Otto, EA, Katsanis, N, Davis, EE, Attié-Bitach, T, Hildebrandt, F, Leroux, MR, and Reiter, JF. "TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone." The Journal of cell biology 209, no. 1 (April 2015): 129-142. Full Text
  - Lock, EF, Soldano, KL, Garrett, ME, Cope, H, Markunas, CA, Fuchs, H, Grant, G, Dunson, DB, Gregory, SG, and Ashley-Koch, AE. "Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation." BMC genomics 16 (January 22, 2015): 11-. Full Text Open Access Copy
  - Liu, Y, Garrett, ME, Dennis, MF, Green, KT, VA Mid-Atlantic MIRECC Registry Workgroup, , Ashley-Koch, AE, Hauser, MA, Beckham, JC, and Kimbrel, NA. "An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. veterans." PloS one 10, no. 3 (January 2015): e0119998-. Full Text
  - Riley, RT, Showker, JL, Lee, CM, Zipperer, CE, Mitchell, TR, Voss, KA, Zitomer, NC, Torres, O, Matute, J, Gregory, SG, Ashley-Koch, AE, Maddox, JR, Gardner, N, and Gelineau-Van Waes, JB. "A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans." Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 32, no. 6 (January 2015): 934-949. Full Text
  - Torres, O, Matute, J, Gelineau-van Waes, J, Maddox, J, Gregory, S, Ashley-Koch, A, Showker, J, Voss, K, and Riley, R. "Human health implications from co-exposure to aflatoxins and fumonisins in maize-based foods in Latin America: Guatemala as a case study." World Mycotoxin Journal 8, no. 2 (January 2015): 143-159. Full Text
  - Smith, TF, Anastopoulos, AD, Garrett, ME, Arias-Vasquez, A, Franke, B, Oades, RD, Sonuga-Barke, E, Asherson, P, Gill, M, Buitelaar, JK, Sergeant, JA, Kollins, SH, Faraone, SV, Ashley-Koch, A, and IMAGE Consortium, . "Angiogenic, neurotrophic, and inflammatory system SNPs moderate the association between birth weight and ADHD symptom severity." American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 165B, no. 8 (December 2014): 691-704. Full Text
  - Liu, Y, Garrett, ME, Yaspan, BL, Bailey, JC, Loomis, SJ, Brilliant, M, Budenz, DL, Christen, WG, Fingert, JH, Gaasterland, D, Gaasterland, T, Kang, JH, Lee, RK, Lichter, P, Moroi, SE, Realini, A, Richards, JE, Schuman, JS, Scott, WK, Singh, K, Sit, AJ, Vollrath, D, Weinreb, R, Wollstein, G, Zack, DJ, Zhang, K, Pericak-Vance, MA, Haines, JL, Pasquale, LR, Wiggs, JL, Allingham, RR, Ashley-Koch, AE, and Hauser, MA. "DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma." Investigative ophthalmology & visual science 55, no. 12 (November 20, 2014): 8251-8258. Full Text
  - Zannas, AS, McQuoid, DR, Payne, ME, MacFall, JR, Ashley-Koch, A, Steffens, DC, Potter, GG, and Taylor, WD. "Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age." The American journal of psychiatry 171, no. 11 (November 2014): 1214-1221. Full Text
  - Guffanti, G, Ashley-Koch, AE, Roberts, AL, Garrett, ME, Solovieff, N, Ratanatharathorn, A, De Vivo, I, Dennis, M, Ranu, H, Smoller, JW, Liu, Y, Purcell, SM, Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, , Beckham, J, Hauser, MA, and Koenen, KC. "No association between RORA polymorphisms and PTSD in two independent samples." Molecular psychiatry 19, no. 10 (October 2014): 1056-1057. Full Text
  - Krupp, DR, Soldano, KL, Garrett, ME, Cope, H, Ashley-Koch, AE, and Gregory, SG. "Missing genetic risk in neural tube defects: can exome sequencing yield an insight?." Birth defects research. Part A, Clinical and molecular teratology 100, no. 8 (August 2014): 642-646. Full Text
  - Markunas, CA, Lock, E, Soldano, K, Cope, H, Ding, C-KC, Enterline, DS, Grant, G, Fuchs, H, Ashley-Koch, AE, and Gregory, SG. "Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics." BMC medical genomics 7 (June 25, 2014): 39-. Full Text
  - Elmariah, H, Garrett, ME, De Castro, LM, Jonassaint, JC, Ataga, KI, Eckman, JR, Ashley-Koch, AE, and Telen, MJ. "Factors associated with survival in a contemporary adult sickle cell disease cohort." American journal of hematology 89, no. 5 (May 2014): 530-535. Full Text
  - Torres, O, Matute, J, Gelineau-van Waes, J, Maddox, JR, Gregory, SG, Ashley-Koch, AE, Showker, JL, Zitomer, NC, Voss, KA, and Riley, RT. "Urinary fumonisin B1 and estimated fumonisin intake in women from high- and low-exposure communities in Guatemala." Mol Nutr Food Res 58, no. 5 (May 2014): 973-983. Full Text Link to Item
  - Moylan, CA, Pang, H, Dellinger, A, Suzuki, A, Garrett, ME, Guy, CD, Murphy, SK, Ashley-Koch, AE, Choi, SS, Michelotti, GA, Hampton, DD, Chen, Y, Tillmann, HL, Hauser, MA, Abdelmalek, MF, and Diehl, AM. "Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease." Hepatology 59, no. 2 (February 2014): 471-482. Full Text Link to Item
  - Sanders, AP, Smeester, L, Rojas, D, DeBussycher, T, Wu, MC, Wright, FA, Zhou, Y-H, Laine, JE, Rager, JE, Swamy, GK, Ashley-Koch, A, Lynn Miranda, M, and Fry, RC. "Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs." Epigenetics 9, no. 2 (February 2014): 212-221. Full Text Link to Item
  - Damiano, CR, Aloi, J, Dunlap, K, Burrus, CJ, Mosner, MG, Kozink, RV, McLaurin, RE, Mullette-Gillman, OA, Carter, RM, Huettel, SA, McClernon, FJ, Ashley-Koch, A, and Dichter, GS. "Association between the oxytocin receptor (OXTR) gene and mesolimbic responses to rewards." Molecular autism 5, no. 1 (January 31, 2014): 7-. Full Text Open Access Copy
  - Carnes, MU, Liu, YP, Allingham, RR, Whigham, BT, Havens, S, Garrett, ME, Qiao, C, NEIGHBORHOOD Consortium Investigators, , Katsanis, N, Wiggs, JL, Pasquale, LR, Ashley-Koch, A, Oh, EC, and Hauser, MA. "Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma." PLoS genetics 10, no. 5 (January 2014): e1004372-. Full Text
  - Elmariah, H, Garrett, ME, De Castro, LM, Jonassaint, JC, Ataga, KI, Eckman, JR, Ashley-Koch, AE, and Telen, MJ. "Factors associated with survival in a contemporary adult sickle cell disease cohort." American Journal of Hematology 89, no. 5 (January 1, 2014): 530-535. Full Text
  - Krupp, DR, Soldano, KL, Garrett, ME, Cope, H, Ashley-Koch, AE, and Gregory, SG. "Missing genetic risk in neural tube defects: Can exome sequencing yield an insight?." Birth Defects Research Part A - Clinical and Molecular Teratology 100, no. 8 (January 1, 2014): 642-646. Full Text
  - Markunas, CA, Enterline, DS, Dunlap, K, Soldano, K, Cope, H, Stajich, J, Grant, G, Fuchs, H, Gregory, SG, and Ashley-Koch, AE. "Genetic evaluation and application of posterior cranial fossa traits as endophenotypes for Chiari type I malformation." Ann Hum Genet 78, no. 1 (January 2014): 1-12. Full Text Link to Item
  - Meltzer, EB, Barry, WT, Yang, IV, Brown, KK, Schwarz, MI, Patel, H, Ashley, A, Noble, PW, Schwartz, DA, and Steele, MP. "Familial and sporadic idiopathic pulmonary fibrosis: making the diagnosis from peripheral blood." BMC Genomics 15, no. 1 (2014): 902-902. Full Text
  - Ozel, AB, Moroi, SE, Reed, DM, Nika, M, Schmidt, CM, Akbari, S, Scott, K, Rozsa, F, Pawar, H, Musch, DC, Lichter, PR, Gaasterland, D, Branham, K, Gilbert, J, Garnai, SJ, Chen, W, Othman, M, Heckenlively, J, Swaroop, A, Abecasis, G, Friedman, DS, Zack, D, Ashley-Koch, A, Ulmer, M, Kang, JH, Liu, Y, Yaspan, BL, Haines, J, Allingham, RR, Hauser, MA, Pasquale, L, Wiggs, J, Richards, JE, and Li, JZ. "Genome-wide association study and meta-analysis of intraocular pressure." Human Genetics 133, no. 1 (January 1, 2014): 41-57. Full Text
  - Ozel, AB, Moroi, SE, Reed, DM, Nika, M, Schmidt, CM, Akbari, S, Scott, K, Rozsa, F, Pawar, H, Musch, DC, Lichter, PR, Gaasterland, D, Branham, K, Gilbert, J, Garnai, SJ, Chen, W, Othman, M, Heckenlively, J, Swaroop, A, Abecasis, G, Friedman, DS, Zack, D, Ashley-Koch, A, Ulmer, M, Kang, JH, NEIGHBOR Consortium, , Liu, Y, Yaspan, BL, Haines, J, Allingham, RR, Hauser, MA, Pasquale, L, Wiggs, J, Richards, JE, and Li, JZ. "Genome-wide association study and meta-analysis of intraocular pressure." Hum Genet 133, no. 1 (January 2014): 41-57. Full Text Link to Item
  - Sanders, AP, Smeester, L, Rojas, D, DeBussycher, T, Wu, MC, Wright, FA, Zhou, YH, Laine, JE, Rager, JE, Swamy, GK, Ashley-Koch, A, Lynn Miranda, M, and Fry, RC. "Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs." Epigenetics : official journal of the DNA Methylation Society 9, no. 2 (January 1, 2014): 212-221. Full Text
  - Lee, C-T, Fuemmeler, BF, McClernon, FJ, Ashley-Koch, A, and Kollins, SH. "Nicotinic receptor gene variants interact with attention deficient hyperactive disorder symptoms to predict smoking trajectories from early adolescence to adulthood." Addict Behav 38, no. 11 (November 2013): 2683-2689. Full Text Link to Item
  - Murphy, SK, Yang, H, Moylan, CA, Pang, H, Dellinger, A, Abdelmalek, MF, Garrett, ME, Ashley-Koch, A, Suzuki, A, Tillmann, HL, Hauser, MA, and Diehl, AM. "Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease." Gastroenterology 145, no. 5 (November 2013): 1076-1087. Full Text Link to Item
  - Soldano, KL, Garrett, ME, Cope, HL, Rusnak, JM, Ellis, NJ, Dunlap, KL, Speer, MC, Gregory, SG, and Ashley-Koch, AE. "Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype." Birth Defects Res B Dev Reprod Toxicol 98, no. 5 (October 2013): 365-373. Full Text Link to Item
  - Liu, Y, Allingham, RR, Qin, X, Layfield, D, Dellinger, AE, Gibson, J, Wheeler, J, Ashley-Koch, AE, Stamer, WD, and Hauser, MA. "Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. (Published online)" Invest Ophthalmol Vis Sci 54, no. 9 (September 27, 2013): 6382-6389. Full Text Link to Item
  - Liu, Y, Hauser, MA, Akafo, SK, Qin, X, Miura, S, Gibson, JR, Wheeler, J, Gaasterland, DE, Challa, P, Herndon, LW, International Consortium of African Ancestry REsearch in Glaucoma, , Ritch, R, Moroi, SE, Pasquale, LR, Girkin, CA, Budenz, DL, Wiggs, JL, Richards, JE, Ashley-Koch, AE, and Allingham, RR. "Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. (Published online)" Invest Ophthalmol Vis Sci 54, no. 9 (September 17, 2013): 6248-6254. Full Text Link to Item
  - Jamerson, BD, Payne, ME, Garrett, ME, Ashley-Koch, AE, Speer, MC, and Steffens, DC. "Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression." Int J Geriatr Psychiatry 28, no. 9 (September 2013): 925-932. Full Text Link to Item
  - Williamson, DM, Marrie, RA, Ashley-Koch, A, and Satten, GA. "Interaction of HLA-DRB1*1501 and TNF-Alpha in a Population-based Case-control Study of Multiple Sclerosis." Immunology and infectious diseases 1, no. 1 (September 2013): 10-17. Full Text
  - Galarneau, G, Coady, S, Garrett, ME, Jeffries, N, Puggal, M, Paltoo, D, Soldano, K, Guasch, A, Ashley-Koch, AE, Telen, MJ, Kutlar, A, Lettre, G, and Papanicolaou, GJ. "Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients." Blood 122, no. 3 (July 18, 2013): 434-442. Full Text Link to Item
  - Zhu, B, Ashley-Koch, AE, and Dunson, DB. "Generalized admixture mapping for complex traits. (Published online)" G3 (Bethesda) 3, no. 7 (July 8, 2013): 1165-1175. Full Text Open Access Copy Link to Item
  - Liu, Y, Rimmler, J, Dennis, MF, Ashley-Koch, AE, Hauser, MA, Mid-Atlantic Mental Illness Research Education and Clinical Center Workgroup, , and Beckham, JC. "Association of Variant rs4790904 in Protein Kinase C Alpha with Posttraumatic Stress Disorder in a U.S. Caucasian and African-American Veteran Sample." Journal of depression & anxiety 2, no. 1 (June 2013): S4001-. Full Text
  - Zannas, AS, McQuoid, DR, Payne, ME, Steffens, DC, MacFall, JR, Ashley-Koch, A, and Taylor, WD. "Negative life stress and longitudinal hippocampal volume changes in older adults with and without depression." J Psychiatr Res 47, no. 6 (June 2013): 829-834. Full Text Link to Item
  - Garrett, ME, Abdelmalek, MF, Ashley-Koch, A, Hauser, MA, Moylan, CA, Pang, H, Diehl, AM, and Tillmann, HL. "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients." J Hepatol 58, no. 2 (February 2013): 402-403. (Letter) Full Text Link to Item
  - Lu, Y, Vitart, V, Burdon, KP, Khor, CC, Bykhovskaya, Y, Mirshahi, A, Hewitt, AW, Koehn, D, Hysi, PG, Ramdas, WD, Zeller, T, Vithana, EN, Cornes, BK, Tay, W-T, Tai, ES, Cheng, C-Y, Liu, J, Foo, J-N, Saw, SM, Thorleifsson, G, Stefansson, K, Dimasi, DP, Mills, RA, Mountain, J, Ang, W, Hoehn, R, Verhoeven, VJM, Grus, F, Wolfs, R, Castagne, R, Lackner, KJ, Springelkamp, H, Yang, J, Jonasson, F, Leung, DYL, Chen, LJ, Tham, CCY, Rudan, I, Vatavuk, Z, Hayward, C, Gibson, J, Cree, AJ, and MacLeod, A et al. "Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus." Nat Genet 45, no. 2 (February 2013): 155-163. Full Text Link to Item
  - Taylor, WD, Zhao, Z, Ashley-Koch, A, Payne, ME, Steffens, DC, Krishnan, RR, Hauser, E, and MacFall, JR. "Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype." Hum Brain Mapp 34, no. 2 (February 2013): 295-303. Full Text Link to Item
  - Cope, H, McMahon, K, Heise, E, Eubanks, S, Garrett, M, Gregory, S, and Ashley-Koch, A. "Outcome and life satisfaction of adults with myelomeningocele." Disability and Health Journal (2013). Full Text
  - Cope, H, McMahon, K, Heise, E, Eubanks, S, Garrett, M, Gregory, S, and Ashley-Koch, A. "Outcome and life satisfaction of adults with myelomeningocele." Disability and Health Journal 6, no. 3 (2013): 236-243. Full Text
  - Garrett, ME, Abdelmalek, MF, Ashley-Koch, A, Hauser, MA, Moylan, CA, Pang, H, Diehl, AM, and Tillmann, HL. "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients." Journal of Hepatology 58, no. 2 (2013): 402-403. Full Text
  - Horstick, EJ, Linsley, JW, Dowling, JJ, Hauser, MA, McDonald, KK, Ashley-Koch, A, Saint-Amant, L, Satish, A, Cui, WW, Zhou, W, Sprague, SM, Stamm, DS, Powell, CM, Speer, MC, Franzini-Armstrong, C, Hirata, H, and Kuwada, JY. "Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy." Nature communications 4 (January 2013): 1952-. Full Text
  - Jamerson, BD, Payne, ME, Garrett, ME, Ashley-Koch, AE, Speer, MC, and Steffens, DC. "Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression." International Journal of Geriatric Psychiatry 28, no. 9 (2013): 925-932. Full Text
  - Markunas, CA, Soldano, K, Dunlap, K, Cope, H, Asiimwe, E, Stajich, J, Enterline, D, Grant, G, Fuchs, H, Gregory, SG, and Ashley-Koch, AE. "Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates. (Published online)" PLoS One 8, no. 4 (2013): e61521-. Full Text Link to Item
  - Taylor, WD, Zhao, Z, Ashley-Koch, A, Payne, ME, Steffens, DC, Krishnan, RR, Hauser, E, and Macfall, JR. "Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype." Human Brain Mapping 34, no. 2 (2013): 295-303. Full Text
  - Zannas, AS, McQuoid, DR, Payne, ME, Steffens, DC, MacFall, JR, Ashley-Koch, A, and Taylor, WD. "Negative life stress and longitudinal hippocampal volume changes in older adults with and without depression." Journal of Psychiatric Research 47, no. 6 (2013): 829-834. Full Text
  - Zhu, B, Dunson, DB, and Ashley-Koch, AE. "Adverse subpopulation regression for multivariate outcomes with high-dimensional predictors." Stat Med 31, no. 29 (December 20, 2012): 4102-4113. Full Text Link to Item
  - Jonassaint, CR, Ashley-Koch, A, Whitfield, KE, Hoyle, RH, Richman, LS, Siegler, IC, Royal, CD, and Williams, R. "The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach." Biol Psychol 91, no. 1 (September 2012): 111-119. Full Text Open Access Copy Link to Item
  - Krupp, DR, Xu, P-T, Thomas, S, Dellinger, A, Etchevers, HC, Vekemans, M, Gilbert, JR, Speer, MC, Ashley-Koch, AE, Gregory, SG, and National Birth Defects Prevention Study, . "Transcriptome profiling of genes involved in neural tube closure during human embryonic development using long serial analysis of gene expression (long-SAGE)." Birth Defects Res A Clin Mol Teratol 94, no. 9 (September 2012): 683-692. Full Text Link to Item
  - Riley, RT, Torres, O, Showker, JL, Zitomer, NC, Matute, J, Voss, KA, Gelineau-van Waes, J, Maddox, JR, Gregory, SG, and Ashley-Koch, AE. "The kinetics of urinary fumonisin B1 excretion in humans consuming maize-based diets." Mol Nutr Food Res 56, no. 9 (September 2012): 1445-1455. Full Text Link to Item
  - Bae, HT, Baldwin, CT, Sebastiani, P, Telen, MJ, Ashley-Koch, A, Garrett, M, Hooper, WC, Bean, CJ, Debaun, MR, Arking, DE, Bhatnagar, P, Casella, JF, Keefer, JR, Barron-Casella, E, Gordeuk, V, Kato, GJ, Minniti, C, Taylor, J, Campbell, A, Luchtman-Jones, L, Hoppe, C, Gladwin, MT, Zhang, Y, and Steinberg, MH. "Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans." Blood 120, no. 9 (August 30, 2012): 1961-1962. (Letter) Full Text Link to Item
  - Ulmer, M, Li, J, Yaspan, BL, Ozel, AB, Richards, JE, Moroi, SE, Hawthorne, F, Budenz, DL, Friedman, DS, Gaasterland, D, Haines, J, Kang, JH, Lee, R, Lichter, P, Liu, Y, Pasquale, LR, Pericak-Vance, M, Realini, A, Schuman, JS, Singh, K, Vollrath, D, Weinreb, R, Wollstein, G, Zack, DJ, Zhang, K, Young, T, Allingham, RR, Wiggs, JL, Ashley-Koch, A, and Hauser, MA. "Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. (Published online)" Invest Ophthalmol Vis Sci 53, no. 8 (July 3, 2012): 4468-4474. Full Text Link to Item
  - Taylor, WD, Benjamin, S, McQuoid, DR, Payne, ME, Krishnan, RR, MacFall, JR, and Ashley-Koch, A. "AGTR1 gene variation: association with depression and frontotemporal morphology." Psychiatry Res 202, no. 2 (May 31, 2012): 104-109. Full Text Link to Item
  - Markunas, CA, Tubbs, RS, Moftakhar, R, Ashley-Koch, AE, Gregory, SG, Oakes, WJ, Speer, MC, and Iskandar, BJ. "Clinical, radiological, and genetic similarities between patients with Chiari Type I and Type 0 malformations." J Neurosurg Pediatr 9, no. 4 (April 2012): 372-378. Full Text Link to Item
  - Wang, L, Ashley-Koch, A, Steffens, DC, Krishnan, KRR, and Taylor, WD. "Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function." Genes Brain Behav 11, no. 3 (April 2012): 352-359. Full Text Link to Item
  - Bidwell, LC, Garrett, ME, McClernon, FJ, Fuemmeler, BF, Williams, RB, Ashley-Koch, AE, and Kollins, SH. "A preliminary analysis of interactions between genotype, retrospective ADHD symptoms, and initial reactions to smoking in a sample of young adults." Nicotine Tob Res 14, no. 2 (February 2012): 229-233. Full Text Link to Item
  - Liu, Y, Whigham, BT, Wheeler, J, Williams, SEI, Rautenbach, RM, Ziskind, A, Ramsay, M, Carmichael, TR, Ashley-Koch, AE, Allingham, RR, and Hauser, MA. "The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma." Mol Vis 18 (2012): 2976-2981. Link to Item
  - McDonald, KK, Stajich, J, Blach, C, Ashley-Koch, AE, and Hauser, MA. "Exome analysis of two limb-girdle muscular dystrophy families: mutations identified and challenges encountered." PLoS One 7, no. 11 (2012): e48864-. Full Text Link to Item
  - Milton, JN, Sebastiani, P, Solovieff, N, Hartley, SW, Bhatnagar, P, Arking, DE, Dworkis, DA, Casella, JF, Barron-Casella, E, Bean, CJ, Hooper, WC, DeBaun, MR, Garrett, ME, Soldano, K, Telen, MJ, Ashley-Koch, A, Gladwin, MT, Baldwin, CT, Steinberg, MH, and Klings, ES. "A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia." PLoS One 7, no. 4 (2012): e34741-. Full Text Link to Item
  - Sullivan, P. "Don't give up on GWAS." Molecular Psychiatry 17, no. 1 (January 2012): 2-3. Full Text
  - Teh, CA, Lee, T-S, Kuchibhatla, M, Ashley-Koch, A, Macfall, J, Krishnan, R, and Beyer, J. "Bipolar disorder, brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and brain morphology." PLoS One 7, no. 7 (2012): e38469-. Full Text Link to Item
  - Williamson, DM, Marrie, RA, Ashley-Koch, A, Schiffer, R, Trottier, J, and Wagner, L. "Design, methodological issues and participation in a multiple sclerosis case-control study." Acta Neurologica Scandinavica 126, no. 3 (2012): 197-204. Full Text
  - Ashley-Koch, AE, Okocha, EC, Garrett, ME, Soldano, K, De Castro, LM, Jonassaint, JC, Orringer, EP, Eckman, JR, and Telen, MJ. "MYH9 and APOL1 are both associated with sickle cell disease nephropathy." Br J Haematol 155, no. 3 (November 2011): 386-394. Full Text Link to Item
  - Anastopoulos, AD, Smith, TF, Garrett, ME, Morrissey-Kane, E, Schatz, NK, Sommer, JL, Kollins, SH, and Ashley-Koch, A. "Self-Regulation of Emotion, Functional Impairment, and Comorbidity Among ChildrenWith AD/HD." J Atten Disord 15, no. 7 (October 2011): 583-592. Full Text Link to Item
  - Swamy, GK, Garrett, ME, Miranda, ML, and Ashley-Koch, AE. "Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers." Am J Med Genet A 155A, no. 6 (June 2011): 1264-1271. Full Text Link to Item
  - Brummett, BH, Siegler, IC, Ashley-Koch, A, and Williams, RB. "Effects of 5HTTLPR on cardiovascular response to an emotional stressor." Psychosom Med 73, no. 4 (May 2011): 318-322. Full Text Link to Item
  - Taylor, WD, McQuoid, DR, Ashley-Koch, A, MacFall, JR, Bridgers, J, Krishnan, RR, and Steffens, DC. "BDNF Val66Met genotype and 6-month remission rates in late-life depression." Pharmacogenomics J 11, no. 2 (April 2011): 146-154. Full Text Link to Item
  - Rizzi, TS, Arias-Vasquez, A, Rommelse, N, Kuntsi, J, Anney, R, Asherson, P, Buitelaar, J, Banaschewski, T, Ebstein, R, Ruano, D, Van der Sluis, S, Markunas, CA, Garrett, ME, Ashley-Koch, AE, Kollins, SH, Anastopoulos, AD, Hansell, NK, Wright, MJ, Montgomery, GW, Martin, NG, Harris, SE, Davies, G, Tenesa, A, Porteous, DJ, Starr, JM, Deary, IJ, St Pourcain, B, Davey Smith, G, Timpson, NJ, Evans, DM, Gill, M, Miranda, A, Mulas, F, Oades, RD, Roeyers, H, Rothenberger, A, and Sergeant, J et al. "The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects." Am J Med Genet B Neuropsychiatr Genet 156, no. 2 (March 2011): 145-157. Full Text Link to Item
  - Williams, RB, Surwit, RS, Siegler, IC, Ashley-Koch, AE, Collins, AL, Helms, MJ, Georgiades, A, Boyle, SH, Brummett, BH, Barefoot, JC, Grichnik, K, Stafford-Smith, M, and Kuhn, CM. "Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men." Psychosom Med 72, no. 7 (September 2010): 601-607. Full Text Link to Item
  - Taylor, WD, Steffens, DC, Ashley-Koch, A, Payne, ME, MacFall, JR, Potocky, CF, and Krishnan, KRR. "Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men." Mol Psychiatry 15, no. 8 (August 2010): 816-822. Full Text Link to Item
  - Kring, SII, Brummett, BH, Barefoot, J, Garrett, ME, Ashley-Koch, AE, Boyle, SH, Siegler, IC, Sørensen, TIA, and Williams, RB. "Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls." Psychosom Med 72, no. 5 (June 2010): 427-433. Full Text Link to Item
  - Markunas, CA, Quinn, KS, Collins, AL, Garrett, ME, Lachiewicz, AM, Sommer, JL, Morrissey-Kane, E, Kollins, SH, Anastopoulos, AD, and Ashley-Koch, AE. "Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families." Psychiatr Genet 20, no. 2 (April 2010): 73-81. Full Text Link to Item
  - Solovieff, N, Milton, JN, Hartley, SW, Sherva, R, Sebastiani, P, Dworkis, DA, Klings, ES, Farrer, LA, Garrett, ME, Ashley-Koch, A, Telen, MJ, Fucharoen, S, Ha, SY, Li, C-K, Chui, DHK, Baldwin, CT, and Steinberg, MH. "Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster." Blood 115, no. 9 (March 4, 2010): 1815-1822. Full Text Link to Item
  - Au, KS, Ashley-Koch, A, and Northrup, H. "Epidemiologic and genetic aspects of spina bifida and other neural tube defects." Dev Disabil Res Rev 16, no. 1 (2010): 6-15. (Review) Full Text Link to Item
  - Sebastiani, P, Solovieff, N, Hartley, SW, Milton, JN, Riva, A, Dworkis, DA, Melista, E, Klings, ES, Garrett, ME, Telen, MJ, Ashley-Koch, A, Baldwin, CT, and Steinberg, MH. "Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study." Am J Hematol 85, no. 1 (January 2010): 29-35. Full Text Link to Item
  - Hong, ED, Taylor, WD, McQuoid, DR, Potter, GG, Payne, ME, Ashley-Koch, A, and Steffens, DC. "Influence of the MTHFR C677T polymorphism on magnetic resonance imaging hyperintensity volume and cognition in geriatric depression." Am J Geriatr Psychiatry 17, no. 10 (October 2009): 847-855. Full Text Link to Item
  - Payne, ME, Jamerson, BD, Potocky, CF, Ashley-Koch, AE, Speer, MC, and Steffens, DC. "Natural food folate and late-life depression." J Nutr Elder 28, no. 4 (October 2009): 348-358. Full Text Link to Item
  - Pan, C-C, McQuoid, DR, Taylor, WD, Payne, ME, Ashley-Koch, A, and Steffens, DC. "Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen." Int J Geriatr Psychiatry 24, no. 8 (August 2009): 847-855. Full Text Link to Item
  - Kollins, SH, Garrett, ME, McClernon, FJ, Lachiewicz, AM, Morrissey-Kane, E, FitzGerald, D, Collins, AL, Anastopoulos, AD, and Ashley-Koch, AE. "Effects of postnatal parental smoking on parent and teacher ratings of ADHD and oppositional symptoms." J Nerv Ment Dis 197, no. 6 (June 2009): 442-449. Full Text Link to Item
  - Fuemmeler, BF, Agurs-Collins, T, McClernon, FJ, Kollins, SH, Garrett, ME, and Ashley-Koch, AE. "Interactions between genotype and depressive symptoms on obesity." Behav Genet 39, no. 3 (May 2009): 296-305. Full Text Link to Item
  - Afenyi-Annan, A, Ashley-Koch, A, and Telen, MJ. "Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean." Br J Haematol 145, no. 2 (April 2009): 266-267. (Letter) Full Text Link to Item
  - Züchner, S, Wendland, JR, Ashley-Koch, AE, Collins, AL, Tran-Viet, KN, Quinn, K, Timpano, KC, Cuccaro, ML, Pericak-Vance, MA, Steffens, DC, Krishnan, KR, Feng, G, and Murphy, DL. "Multiple rare SAPAP3 missense variants in trichotillomania and OCD." Mol Psychiatry 14, no. 1 (January 2009): 6-9. (Letter, Review) Full Text Link to Item
  - Kollins, SH, Anastopoulos, AD, Lachiewicz, AM, FitzGerald, D, Morrissey-Kane, E, Garrett, ME, Keatts, SL, and Ashley-Koch, AE. "SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families." Am J Med Genet B Neuropsychiatr Genet 147B, no. 8 (December 5, 2008): 1580-1588. Full Text Link to Item
  - Silbermins, D, De Castro, LM, Ashley-Koch, AE, Jonassaint, JC, Garrett, ME, Eckman, JR, Orringer, EP, and Telen, MJ. "Prolonged Survival despite High Disease Burden in Elderly (>= 55) Patients with Hb SS or Hb S beta 0 Thalassemia." BLOOD 112, no. 11 (November 16, 2008): 264-264. Link to Item
  - Adam, S, Jonassaint, J, Kruger, H, Kail, M, Orringer, EP, Eckman, JR, Ashley-Koch, A, Telen, MJ, and De Castro, LM. "Surgical and obstetric outcomes in adults with sickle cell disease." Am J Med 121, no. 10 (October 2008): 916-921. Full Text Link to Item
  - Brummett, BH, Boyle, SH, Siegler, IC, Kuhn, CM, Surwit, RS, Garrett, ME, Collins, A, Ashley-Koch, A, and Williams, RB. "HPA axis function in male caregivers: effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR)." Biol Psychol 79, no. 2 (October 2008): 250-255. Full Text Link to Item
  - Deak, KL, Siegel, DG, George, TM, Gregory, S, Ashley-Koch, A, Speer, MC, and NTD Collaborative Group, . "Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects." Birth Defects Res A Clin Mol Teratol 82, no. 10 (October 2008): 662-669. Full Text Link to Item
  - Brummett, BH, Muller, CL, Collins, AL, Boyle, SH, Kuhn, CM, Siegler, IC, Williams, RB, and Ashley-Koch, A. "5-HTTLPR and gender moderate changes in negative affect responses to tryptophan infusion." Behav Genet 38, no. 5 (September 2008): 476-483. Full Text Link to Item
  - Ashley-Koch, AE, Elliott, L, Kail, ME, De Castro, LM, Jonassaint, J, Jackson, TL, Price, J, Ataga, KI, Levesque, MC, Weinberg, JB, Orringer, EP, Collins, A, Vance, JM, and Telen, MJ. "Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease." Blood 111, no. 12 (June 15, 2008): 5721-5726. Full Text Link to Item
  - Stamm, DS, Siegel, DG, Mehltretter, L, Connelly, JJ, Trott, A, Ellis, N, Zismann, V, Stephan, DA, George, TM, Vekemans, M, Ashley-Koch, A, Gilbert, JR, Gregory, SG, Speer, MC, and NTD Collaborative Group, . "Refinement of 2q and 7p loci in a large multiplex NTD family." Birth Defects Res A Clin Mol Teratol 82, no. 6 (June 2008): 441-452. Full Text Link to Item
  - Afenyi-Annan, A, Kail, M, Combs, MR, Orringer, EP, Ashley-Koch, A, and Telen, MJ. "Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease." Transfusion 48, no. 5 (May 2008): 917-924. Full Text Link to Item
  - Eyler, CE, Jackson, T, Elliott, LE, De Castro, LM, Jonassaint, J, Ashley-Koch, A, and Telen, MJ. "beta(2)-Adrenergic receptor and adenylate cyclase gene polymorphisms affect sickle red cell adhesion." Br J Haematol 141, no. 1 (April 2008): 105-108. Full Text Link to Item
  - Eyler, CE, Jackson, T, Elliott, LE, De Castro, LM, Jonassaint, J, Ashley-Koch, A, and Telen, MJ. "β2-Adrenergic receptor and adenylate cyclase gene polymorphisms affect sickle red cell adhesion." British Journal of Haematology 141, no. 1 (April 1, 2008): 105-108. Full Text
  - Brummett, BH, Boyle, SH, Siegler, IC, Zuchner, S, Ashley-Koch, A, and Williams, RB. "Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR)." Med Sci Monit 14, no. 2 (February 2008): CR57-CR61. Link to Item
  - Fuemmeler, BF, Agurs-Collins, TD, McClernon, FJ, Kollins, SH, Kail, ME, Bergen, AW, and Ashley-Koch, AE. "Genes implicated in serotonergic and dopaminergic functioning predict BMI categories." Obesity (Silver Spring) 16, no. 2 (February 2008): 348-355. Full Text Link to Item
  - Brummett, BH, Boyle, SH, Siegler, IC, Kuhn, CM, Ashley-Koch, A, Jonassaint, CR, Züchner, S, Collins, A, and Williams, RB. "Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR)." Behav Genet 38, no. 1 (January 2008): 34-43. Full Text Link to Item
  - De Castro, LM, Jonassaint, JC, Graham, FL, Ashley-Koch, A, and Telen, MJ. "Pulmonary hypertension associated with sickle cell disease: clinical and laboratory endpoints and disease outcomes." Am J Hematol 83, no. 1 (January 2008): 19-25. Full Text Link to Item
  - McClernon, FJ, Fuemmeler, BF, Kollins, SH, Kail, ME, and Ashley-Koch, AE. "Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults." Nicotine Tob Res 10, no. 1 (January 2008): 117-127. Full Text Link to Item
  - Williams, RB, Marchuk, DA, Siegler, IC, Barefoot, JC, Helms, MJ, Brummett, BH, Surwit, RS, Lane, JD, Kuhn, CM, Gadde, KM, Ashley-Koch, A, Svenson, IK, and Schanberg, SM. "Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress." Psychosom Med 70, no. 1 (January 2008): 32-39. Full Text Link to Item
  - Brummett, BH, Krystal, AD, Ashley-Koch, A, Kuhn, CM, Züchner, S, Siegler, IC, Barefoot, JC, Ballard, EL, Gwyther, LP, and Williams, RB. "Sleep quality varies as a function of 5-HTTLPR genotype and stress." Psychosom Med 69, no. 7 (September 2007): 621-624. Full Text Link to Item
  - Ashley-Koch, AE, Jaworski, J, Ma, DQ, Mei, H, Ritchie, MD, Skaar, DA, Robert Delong, G, Worley, G, Abramson, RK, Wright, HH, Cuccaro, ML, Gilbert, JR, Martin, ER, and Pericak-Vance, MA. "Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk." Psychiatr Genet 17, no. 4 (August 2007): 221-226. Full Text Link to Item
  - Beetz, C, Zuchner, S, Ashley-Koch, A, Auer-Grumbach, M, Byrne, P, Chinnery, PF, Hutchinson, M, McDermott, CJ, Meijer, IA, Nygren, AOH, Pericak-Vance, M, Pyle, A, Rouleau, GA, Schickel, J, Shaw, PJ, and Deufel, T. "Linkage to a known gene but no mutation identified: comprehensive reanalysis of SPG4 HSP pedigrees reveals large deletions as the sole cause." Hum Mutat 28, no. 7 (July 2007): 739-740. (Letter) Full Text Link to Item
  - Brummett, BH, Krystal, AD, Siegler, IC, Kuhn, C, Surwit, RS, Züchner, S, Ashley-Koch, A, Barefoot, JC, and Williams, RB. "Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality." Psychosom Med 69, no. 5 (June 2007): 396-401. Full Text Link to Item
  - Schmidt, H, Williamson, D, and Ashley-Koch, A. "HLA-DR15 haplotype and multiple sclerosis: a HuGE review." Am J Epidemiol 165, no. 10 (May 15, 2007): 1097-1109. (Review) Full Text Link to Item
  - Elliott, L, Ashley-Koch, AE, De Castro, L, Jonassaint, J, Price, J, Ataga, KI, Levesque, MC, Brice Weinberg, J, Eckman, JR, Orringer, EP, Vance, JM, and Telen, MJ. "Genetic polymorphisms associated with priapism in sickle cell disease." Br J Haematol 137, no. 3 (May 2007): 262-267. Full Text Link to Item
  - Elliott, L, Ashley-Koch, AE, Jonassaint, J, Price, J, Galloway, J, Ataga, KI, Levesque, MC, Weinberg, JB, Eckman, JR, Orringer, EP, Vance, JM, and Telen, MJ. "Genetic polymorphisms associated with priapism in sickle cell disease." BLOOD 108, no. 11 (November 16, 2006): 236A-237A. Link to Item
  - Zuchner, S, Cuccaro, ML, Tran-Viet, KN, Cope, H, Krishnan, RR, Pericak-Vance, MA, Wright, HH, and Ashley-Koch, A. "SLITRK1 mutations in trichotillomania." Mol Psychiatry 11, no. 10 (October 2006): 887-889. (Letter) Full Text Link to Item
  - Züchner, S, Wang, G, Tran-Viet, K-N, Nance, MA, Gaskell, PC, Vance, JM, Ashley-Koch, AE, and Pericak-Vance, MA. "Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31." Am J Hum Genet 79, no. 2 (August 2006): 365-369. Full Text Link to Item
  - Ashley-Koch, AE, Mei, H, Jaworski, J, Ma, DQ, Ritchie, MD, Menold, MM, Delong, GR, Abramson, RK, Wright, HH, Hussman, JP, Cuccaro, ML, Gilbert, JR, Martin, ER, and Pericak-Vance, MA. "An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder." Ann Hum Genet 70, no. Pt 3 (May 2006): 281-292. Full Text Link to Item
  - Rabionet, R, McCauley, JL, Jaworski, JM, Ashley-Koch, AE, Martin, ER, Sutcliffe, JS, Haines, JL, DeLong, GR, Abramson, RK, Wright, HH, Cuccaro, ML, Gilbert, JR, and Pericak-Vance, MA. "Lack of association between autism and SLC25A12." Am J Psychiatry 163, no. 5 (May 2006): 929-931. Full Text Link to Item
  - Züchner, S, Kail, ME, Nance, MA, Gaskell, PC, Svenson, IK, Marchuk, DA, Pericak-Vance, MA, and Ashley-Koch, AE. "A new locus for dominant hereditary spastic paraplegia maps to chromosome 2p12." Neurogenetics 7, no. 2 (May 2006): 127-129. (Letter) Full Text Link to Item
  - ASHLEY-KOCH, A. "An analysis paradigm for investigating multi-locus effects in complex disease : examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder." Ann Hum Genet 70 (2006): 281-292. Full Text
  - Züchner, S, Cuccaro, ML, Tran-Viet, KN, Cope, H, Krishnan, RR, Pericak-Vance, MA, Wright, HH, and Ashley-Koch, A. "SLITRK1 mutations in trichotillomania." Molecular Psychiatry 11, no. 10 (2006): 887--. Full Text
  - Mei, H, Ma, D, Ashley-Koch, A, and Martin, ER. "Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data. (Published online)" BMC Genet 6 Suppl 1 (December 30, 2005): S145-. Full Text Link to Item
  - Ashley-Koch, A. "Determining Genetic Component of a Disease." (October 7, 2005): 91-115. (Chapter) Full Text
  - Ma, DQ, Whitehead, PL, Menold, MM, Martin, ER, Ashley-Koch, AE, Mei, H, Ritchie, MD, Delong, GR, Abramson, RK, Wright, HH, Cuccaro, ML, Hussman, JP, Gilbert, JR, and Pericak-Vance, MA. "Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism." Am J Hum Genet 77, no. 3 (September 2005): 377-388. Full Text Link to Item
  - Skaar, DA, Shao, Y, Haines, JL, Stenger, JE, Jaworski, J, Martin, ER, DeLong, GR, Moore, JH, McCauley, JL, Sutcliffe, JS, Ashley-Koch, AE, Cuccaro, ML, Folstein, SE, Gilbert, JR, and Pericak-Vance, MA. "Analysis of the RELN gene as a genetic risk factor for autism." Mol Psychiatry 10, no. 6 (June 2005): 563-571. Full Text Link to Item
  - Ashley-Koch, AE, Shao, Y, Rimmler, JB, Gaskell, PC, Welsh-Bohmer, KA, Jackson, CE, Scott, WK, Haines, JL, and Pericak-Vance, MA. "An autosomal genomic screen for dementia in an extended Amish family." Neurosci Lett 379, no. 3 (May 13, 2005): 199-204. Full Text Link to Item
  - Boyles, AL, Scott, WK, Martin, ER, Schmidt, S, Li, Y-J, Ashley-Koch, A, Bass, MP, Schmidt, M, Pericak-Vance, MA, Speer, MC, and Hauser, ER. "Linkage disequilibrium inflates type I error rates in multipoint linkage analysis when parental genotypes are missing." Hum Hered 59, no. 4 (2005): 220-227. Full Text Link to Item
  - Rabionet, R, Jaworski, JM, Ashley-Koch, AE, Martin, ER, Sutcliffe, JS, Haines, JL, Delong, GR, Abramson, RK, Wright, HH, Cuccaro, ML, Gilbert, JR, and Pericak-Vance, MA. "Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes." Neurosci Lett 372, no. 3 (December 6, 2004): 209-214. Full Text Link to Item
  - Svenson, IK, Kloos, MT, Gaskell, PC, Nance, MA, Garbern, JY, Hisanaga, S-I, Pericak-Vance, MA, Ashley-Koch, AE, and Marchuk, DA. "Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations." Neurogenetics 5, no. 3 (September 2004): 157-164. Full Text Link to Item
  - Yip, AG, Dürr, A, Marchuk, DA, Ashley-Koch, A, Hentati, A, Rubinsztein, DC, and Reid, E. "Meta-analysis of age at onset in spastin-associated hereditary spastic paraplegia provides no evidence for a correlation with mutational class." J Med Genet 40, no. 9 (September 2003): e106-. Link to Item
  - Carney, RM, Wolpert, CM, Ravan, SA, Shahbazian, M, Ashley-Koch, A, Cuccaro, ML, Vance, JM, and Pericak-Vance, MA. "Identification of MeCP2 mutations in a series of females with autistic disorder." Pediatr Neurol 28, no. 3 (March 2003): 205-211. Link to Item
  - Rampersaud, E, Allen, A, Li, YJ, Shao, Y, Bass, M, Haynes, C, Ashley Koch, A, Martin, ER, Schmidt, S, and Hauser, ER. "Adjusting for covariates on a slippery slope: linkage analysis of change over time." BMC genetics 4 Suppl 1 (2003): S50-. (Academic Article)
  - Reid, E, Kloos, M, Ashley-Koch, A, Hughes, L, Bevan, S, Svenson, IK, Graham, FL, Gaskell, PC, Dearlove, A, Pericak-Vance, MA, Rubinsztein, DC, and Marchuk, DA. "A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10)." Am J Hum Genet 71, no. 5 (November 2002): 1189-1194. Full Text Link to Item
  - Lamb, SE, Bartlett, HP, Ashley, A, and Bird, W. "Can lay-led walking programmes increase physical activity in middle aged adults? A randomised controlled trial." J Epidemiol Community Health 56, no. 4 (April 2002): 246-252. Link to Item
  - Shao, Y, Raiford, KL, Wolpert, CM, Cope, HA, Ravan, SA, Ashley-Koch, AA, Abramson, RK, Wright, HH, DeLong, RG, Gilbert, JR, Cuccaro, ML, and Pericak-Vance, MA. "Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder." Am J Hum Genet 70, no. 4 (April 2002): 1058-1061. Full Text Link to Item
  - McCoy, PA, Shao, Y, Wolpert, CM, Donnelly, SL, Ashley-Koch, A, Abel, HL, Ravan, SA, Abramson, RK, Wright, HH, DeLong, GR, Cuccaro, ML, Gilbert, JR, and Pericak-Vance, MA. "No association between the WNT2 gene and autistic disorder." Am J Med Genet 114, no. 1 (January 8, 2002): 106-109. Link to Item
  - Shao, Y, Wolpert, CM, Raiford, KL, Menold, MM, Donnelly, SL, Ravan, SA, Bass, MP, McClain, C, von Wendt, L, Vance, JM, Abramson, RH, Wright, HH, Ashley-Koch, A, Gilbert, JR, DeLong, RG, Cuccaro, ML, and Pericak-Vance, MA. "Genomic screen and follow-up analysis for autistic disorder." Am J Med Genet 114, no. 1 (January 8, 2002): 99-105. Link to Item
  - Svenson, IK, Ashley-Koch, AE, Pericak-Vance, MA, and Marchuk, DA. "A second leaky splice-site mutation in the spastin gene." Am J Hum Genet 69, no. 6 (December 2001): 1407-1409. (Letter) Full Text Link to Item
  - Ashley-Koch, A, Murphy, CC, Khoury, MJ, and Boyle, CA. "Contribution of sickle cell disease to the occurrence of developmental disabilities: a population-based study." Genet Med 3, no. 3 (May 2001): 181-186. Link to Item
  - Svenson, IK, Ashley-Koch, AE, Gaskell, PC, Riney, TJ, Cumming, WJ, Kingston, HM, Hogan, EL, Boustany, RM, Vance, JM, Nance, MA, Pericak-Vance, MA, and Marchuk, DA. "Identification and expression analysis of spastin gene mutations in hereditary spastic paraplegia." Am J Hum Genet 68, no. 5 (May 2001): 1077-1085. Full Text Link to Item
  - Ashley-Koch, A, Bonner, ER, Gaskell, PC, West, SG, Tim, R, Wolpert, CM, Jones, R, Farrell, CD, Nance, M, Svenson, IK, Marchuk, DA, Boustany, RM, Vance, JM, Scott, WK, and Pericak-Vance, MA. "Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia." Neurogenetics 3, no. 2 (March 2001): 91-97. Link to Item
  - Ashley-Koch, AE, Carney, RJ, Wolpert, CM, Cuccaro, ML, Gilbert, JR, Vance, JM, and Pericak-Vance, MA. "Screening for MECP2 mutations in females with autistic disorder." American Journal of Medical Genetics - Neuropsychiatric Genetics 105, no. 7 (2001): 632--.
  - McCoy, PA, Shao, S, Wolpert, CM, Donnelly, SL, Ashley-Koch, A, Gilbert, JR, and Pericak-Vance, MA. "Analysis of genetic risk factors for autistic disorder on Chromosome 7." American Journal of Medical Genetics - Neuropsychiatric Genetics 105, no. 7 (2001): 631-632.
  - Shao, Y, Raiford, K, Wolpert, CM, Ashley-Koch, A, Cuccaro, ML, Gilbert, JR, and Pericak-Vance, MA. "Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder." American Journal of Medical Genetics - Neuropsychiatric Genetics 105, no. 7 (2001): 594--.
  - Svenson, IK, Ashley-Koch, AE, Gaskell, PC, Riney, TJ, Warner, C, Farrell, CD, Boustany, RMN, Haines, JL, Nance, MA, Pericak-Vance, MA, and Marchuk, DA. "Mutation analysis of the spastin gene in hereditary spastic paraplegia type 4 - evidence of aberrant transcript splicing caused by mutations in noncanonical splice site sequences." AMERICAN JOURNAL OF HUMAN GENETICS 67, no. 4 (October 2000): 375-375. Link to Item
  - Ashley-Koch, A, Yang, Q, and Olney, RS. "Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review." Am J Epidemiol 151, no. 9 (May 1, 2000): 839-845. (Review) Link to Item
  - Basu, S, Ashley-Koch, A, Wolpert, CM, Menold, MM, Matsumoto, N, Basu, S, Ashley-Koch, A, Wolpert, CM, Menold, MM, Matsumoto, N, Greenblatt, DM, Powell, CM, Qumsiyeh, MB, Cuccaro, ML, Ledbetter, DH, Green, ED, Vance, JM, Pericak-Vance, MA, and Gilbert, JR. "Identification of autism susceptibility candidates on 7q." American Journal of Medical Genetics - Neuropsychiatric Genetics 96, no. 4 (2000): 479--.
  - Santangelo, S, Ashley-Koch, A, Pericak-Vance, M, Silverman, J, Smith, CJ, and Buxbaum, J. "Combined analysis of data on chromosome 7q from three autism genome scans." American Journal of Medical Genetics - Neuropsychiatric Genetics 96, no. 4 (2000): 480--.
  - Ashley-Koch, A, Wolpert, CM, Menold, MM, Zaeem, L, Basu, S, Donnelly, SL, Ravan, SA, Powell, CM, Qumsiyeh, MB, Aylsworth, AS, Vance, JM, Gilbert, JR, Wright, HH, Abramson, RK, DeLong, GR, Cuccaro, ML, and Pericak-Vance, MA. "Genetic studies of autistic disorder and chromosome 7." Genomics 61, no. 3 (November 1, 1999): 227-236. Full Text Link to Item
  - Hauser, ER, Ashley-Koch, A, Pericak-Vance, MA, and Boehnke, M. "Affected sibpair analysis: Exploring the efficiency of fine mapping in the presence of genotyping error." AMERICAN JOURNAL OF HUMAN GENETICS 65, no. 4 (October 1999): A99-A99. Link to Item
  - Anderson, JL, Hauser, ER, Martin, ER, Scott, WK, Ashley-Koch, A, Kim, KJ, Monks, SA, Haynes, CS, Speer, MC, and Pericak-Vance, MA. "Complete genomic screen for disease susceptibility loci in nuclear families." Genet Epidemiol 17 Suppl 1 (1999): S473-S478. Link to Item
  - Ashley-Koch, AE, Robinson, H, Glicksman, AE, Nolin, SL, Schwartz, CE, Brown, WT, Turner, G, and Sherman, SL. "Examination of factors associated with instability of the FMR1 CGG repeat." Am J Hum Genet 63, no. 3 (September 1998): 776-785. Full Text Link to Item
  - Sun, F, Ashley-Koch, AE, Durham, LK, Feingold, E, Halloran, ME, Manatunga, AK, and Sherman, SL. "Testing for contributions of mitochondrial DNA mutations to complex diseases." Genet Epidemiol 15, no. 5 (1998): 451-469. Full Text Link to Item
  - Savage, A, Sun, F, Crawford, DC, Ashley, AE, Yang, Q, and Sherman, SL. "Sequential sib-pair and association studies to detect genes in quantitative traits." Genet Epidemiol 14, no. 6 (1997): 885-890. Full Text Link to Item
  - Nolin, SL, Lewis, FA, Ye, LL, Houck, GE, Glicksman, AE, Limprasert, P, Li, SY, Zhong, N, Ashley, AE, Feingold, E, Sherman, SL, and Brown, WT. "Familial transmission of the FMR1 CGG repeat." Am J Hum Genet 59, no. 6 (December 1996): 1252-1261. Link to Item
  - Meadows, KL, Pettay, D, Newman, J, Hersey, J, Ashley, AE, and Sherman, SL. "Survey of the fragile X syndrome and the fragile X E syndrome in a special education needs population." American Journal of Medical Genetics 64, no. 2 (August 9, 1996): 428-433. Full Text
  - Meadows, KL, Pettay, D, Newman, J, Hersey, J, Ashley, AE, and Sherman, SL. "Survey of the fragile X syndrome and the fragile X E syndrome in a special education needs population." Am J Med Genet 64, no. 2 (August 9, 1996): 428-433. Full Text Link to Item
  - Sherman, SL, Meadows, KL, and Ashley, AE. "Examination of factors that influence the expansion of the fragile X mutation in a sample of conceptuses from known carrier females." American Journal of Medical Genetics 64, no. 2 (August 9, 1996): 256-260. Full Text
  - Sherman, SL, Meadows, KL, and Ashley, AE. "Examination of factors that influence the expansion of the fragile X mutation in a sample of conceptuses from known carrier females." Am J Med Genet 64, no. 2 (August 9, 1996): 256-260. Full Text Link to Item
  - Ashley, AE, and Sherman, SL. "Population dynamics of a meiotic/mitotic expansion model for the fragile X syndrome." Am J Hum Genet 57, no. 6 (December 1995): 1414-1425. Link to Item
  - Falk, CT, Ashley, A, Lamb, N, and Sherman, SL. "Identification of susceptibility loci contributing to a complex disease using conventional segregation, linkage, and association methods." Genet Epidemiol 12, no. 6 (1995): 601-606. Full Text Link to Item
  - Speer, MC, Pericak-Vance, MA, Yamaoka, L, Hung, WY, Ashley, A, Stajich, JM, and Roses, AD. "Presymptomatic and prenatal diagnosis in myotonic dystrophy by genetic linkage studies." Neurology 40, no. 4 (April 1990): 671-676. Link to Item
- Other Articles
  - Aung, T, Ozaki, M, Mizoguchi, T, Allingham, RR, Li, Z, Haripriya, A, Nakano, S, Uebe, S, Harder, JM, Chan, ASY, Lee, MC, Burdon, KP, Astakhov, YS, Abu-Amero, KK, Zenteno, JC, Nilgün, Y, Zarnowski, T, Pakravan, M, Safieh, LA, Jia, L, Wang, YX, Williams, S, Paoli, D, Schlottmann, PG, Huang, L, Sim, KS, Foo, JN, Nakano, M, Ikeda, Y, Kumar, RS, Ueno, M, Manabe, S-I, Hayashi, K, Kazama, S, Ideta, R, Mori, Y, Miyata, K, Sugiyama, K, Higashide, T, Chihara, E, Inoue, K, Ishiko, S, Yoshida, A, and Yanagi, M et al. "Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome." Nature genetics 47, no. 6 (June 2015): 689-. Full Text
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