Scholars@Duke
Alyssa Soskis

Selected Publications

Association of Anti-Ro52 Seropositive Interstitial Lung Disease With a Higher Risk of Disease Progression and Mortality.

Journal Article Chest · October 2025 BACKGROUND: Identifying biomarkers is vital for interstitial lung disease (ILD) management and prognostication. Although anti-Ro52 antibodies frequently are detected in autoimmune diseases, their significance in ILD remains unclear. RESEARCH QUESTION: What ... Full text Link to item Cite

An App Platform-Facilitated Collaborative Palliative Care Intervention for Outpatients With Interstitial Lung Disease: A Pilot Randomized Trial.

Journal Article Am J Hosp Palliat Care · July 2025 Rationale: Outpatients with interstitial lung disease often experience serious symptoms, yet infrequently receive palliative care. Objective: To determine the feasibility and clinical impact of a mobile application (PCplanner) in an outpatient setting. Met ... Full text Link to item Cite

Multidisciplinary Approach to Familial Pulmonary Fibrosis.

Journal Article Radiographics · July 2025 Familial pulmonary fibrosis (FPF) represents a subset of patients with interstitial lung disease that can be a diagnostic dilemma for the clinician and radiologist. Diagnosis can be challenging, as the age at presentation and penetrance can vary even among ... Full text Link to item Cite

Characterizing Progressive Pulmonary Fibrosis in a Multi-center Real World Cohort

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2024 Cite

E-Cigarette Use, Small Airway Fibrosis, and Constrictive Bronchiolitis.

Journal Article NEJM Evid · June 2022 BACKGROUND: Vaping, including the use of electronic cigarettes (e-cigarettes), has become increasingly prevalent, yet the associated long-term health risks are largely unknown. Given the prevalence of use, particularly among adolescents early in their life ... Full text Link to item Cite

Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza: A Systematic Review.

Journal Article Chest · January 2021 BACKGROUND: Patients with severe coronavirus disease 2019 (COVID-19) have respiratory failure with hypoxemia and acute bilateral pulmonary infiltrates, consistent with ARDS. Respiratory failure in COVID-19 might represent a novel pathologic entity. RESEARC ... Full text Link to item Cite

Antifibrotic Therapy: Is There a Role in Myositis-Interstitial Lung Disease?

Journal Article Respiration · 2021 Interstitial lung disease (ILD) is a cause of substantial morbidity and mortality amongst autoimmune diseases, including myositis. Despite first-line therapy with immunosuppression, many inflammatory ILDs advance to a fibrotic stage. In such patients, prog ... Full text Link to item Cite

Delayed Cardiotoxicity From a Massive Nortriptyline Overdose Requiring Prolonged Treatment.

Journal Article J Pharm Pract · August 2020 PURPOSE: A case of a nortriptyline overdose complicated by delayed ventricular arrhythmias necessitating prolonged sodium bicarbonate infusion is presented, along with a review of tricyclic antidepressant (TCA) toxicology and key concepts for massive overd ... Full text Link to item Cite

Presentations and outcomes of interstitial lung disease and the anti-Ro52 autoantibody.

Journal Article Respir Res · November 12, 2019 BACKGROUND: Distinct clinical presentations of interstitial lung disease (ILD) with the myositis-specific antibodies, including anti-synthetase antibodies, are well-recognized. However, the association between ILD and the myositis-associated antibodies, in ... Full text Link to item Cite

Advances in Interstitial Lung Disease Genetics.

Journal Article Am J Respir Crit Care Med · July 15, 2019 Full text Link to item Cite

Internal Medicine Residents' Exposure to and Confidence in Managing Hospital Acute Clinical Events.

Journal Article J Hosp Med · April 2019 BACKGROUND: Internal Medicine (IM) residency graduates should be able to manage hospital emergencies, but the rare and critical nature of such events poses an educational challenge. IM residents' exposure to inpatient acute clinical events is currently unk ... Full text Link to item Cite

Lymphangioleiomyomatosis.

Journal Article N Engl J Med · June 7, 2018 Full text Link to item Cite