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Amanda Van Swearingen

Research Program Leader, Sr
Medicine
232 Baker House, Trent Drive, Box #3381, Durham, NC 27710
20 Sydenham Road, Durham, NC 27713

Overview


Education and Training

Postdoctoral Research Associate, UNC-Chapel Hill, 01/2013-02/2017

PhD, Molecular Cancer Biology, Duke University, 2012

BS, Biology, Wake Forest University, 2007

Current Appointments & Affiliations


Research Program Leader, Sr Medicine, Clinical Science Departments

Recent Publications


A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases.

Journal Article Acta Neuropathol Commun · June 2, 2025 BACKGROUND: Melanoma brain metastases (MBM) have a unique molecular profile compared to extracranial metastases (ECM). Description of the biological features and clinical outcomes of MBM will facilitate the design of rational therapies. METHODS: We examine ... Full text Link to item Cite

Genomic and immune profiling of breast cancer brain metastases.

Journal Article Acta Neuropathol Commun · May 12, 2025 BACKGROUND: Brain metastases (BrM) arising from breast cancer (BC) are an increasing consequence of advanced disease, with up to half of patients with metastatic HER2 + or triple negative BC experiencing central nervous system (CNS) recurrence. The genomic ... Full text Link to item Cite
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Recent Grants


CNS PATTERN: CNS Progression After Targeted Therapy and Effect of Radiation in NSCLC

FellowshipData Manager · Awarded by Lung Cancer Initiative of North Carolina · 2025 - 2026

Ancestry-related RNA splicing and immune expression in metastatic breast cancer

ResearchResearch Associate · Awarded by Susan G. Komen Breast Cancer Foundation · 2022 - 2026

Breast Cancer Brain Metastases: Integrating Immunogenomic and Phenotypic Vulnerabilities to Improve Outcomes

ResearchProject Planner · Awarded by Department of Defense · 2025 - 2026

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