Current Appointments & Affiliations
Assistant Professor in Surgery
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Recent Publications
CD27 agonism enhances long-lived CD4 T cell vaccine responses critical for antitumor immunity.
Journal Article Sci Immunol · December 19, 2025 Tumor antigen vaccination represents an appealing approach for cancer but has failed to materialize as oncologic standard of care. To understand long-term vaccine efficacy, we conducted a retrospective analysis of patients with human epidermal growth recep ... Full text Link to item CiteClinical impact of concurrent autologous adoptive T cells immunotherapy in active COVID-19 infected cancer patients for chemotherapy.
Journal Article Infect Agent Cancer · April 9, 2025 BACKGROUND: The concurrent presence of COVID-19 infection in advanced cancer patients has increased the mortality since the compromised immunity was inevitably worsen. The role and clinical impact of autologous adoptive T cell immunotherapy (ACT) designed ... Full text Link to item CiteVaccines targeting ESR1 activating mutations elicit anti-tumor immune responses and suppress estrogen signaling in therapy resistant ER+ breast cancer.
Journal Article Hum Vaccin Immunother · December 31, 2024 ER+ breast cancers (BC) are characterized by the elevated expression and signaling of estrogen receptor alpha (ESR1), which renders them sensitive to anti-endocrine therapy. While these therapies are clinically effective, prolonged treatment inevitably res ... Full text Link to item CiteRecent Grants
Single Cell and Spatial Analysis of Lethal Breast Cancers
ResearchCo Investigator · Awarded by Department of Defense · 2024 - 2028Therapeutic targeting of breast cancer and host immune responses at inflection points in the disease trajectory
ResearchCo Investigator · Awarded by Department of Defense · 2021 - 2026Beyond PD1: An immunotherapeutic strategy to stimulate and enable both T-cell and B-cell responses in immunosuppressive and non-mutated metastatic breast cancer
ResearchCo Investigator · Awarded by Department of Defense · 2020 - 2026View All Grants
Education, Training & Certifications
University of Florida ·
1997
Ph.D.